Expression and clinicopathological significance of OPN and CD44v6 in lung cancer

Chinese Journal of Lung Cancer

Volumn 10, Issue 2, 2007, Pages 98-101

  Yang, Yanjuan ^a   Cheng, Deyun ^a   Li, Xixia ^a   Fang, Xun ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

CD44v6; Immunohistochemistry; Lung neoplasms; OPN

Indexed keywords

CD44V6 ANTIGEN; OSTEOPONTIN;

ARTICLE; CANCER STAGING; CELL DIFFERENTIATION; CORRELATION ANALYSIS; IMMUNOHISTOCHEMISTRY; LUNG NON SMALL CELL CANCER; PROTEIN EXPRESSION;

EID: 34247545233     PISSN: 10093419     EISSN: 19996187     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Shijubo N, Uede T, Kon S, et al. Vascular endothelial growth factor and osteopontin in stage I lung adenocarcinoma. Am J Respir Crit Care Med,1999,160(4):1269-1273.
2. Zhang J, Takahashi K, Takahashi F, et al. Differential osteopontin expression in lung cancer. Cancer Lett,2001,171(2):215-222.
3. Zuo WL, Li HG. Relationship of the expression of CD44v6 and paxillin to the prognosis of non-small cell lung carcinoma. J SichuanUniv(MedSciEdit),2003, 34(3):484-485,488.
4. Wang FL, Wei LX. Expression of CD44 variant exon 6 in lung cancers. Acta Acad Med Sin,2001,23(4):401-402.
5. Yu J, Pan TC, Li J, et al. Expression and clinicopathologic significance of OPN, CD44v6 and MMP-2 in squamous cell carcinoma and adenocarcinoma of the lung. Chin J Lung Cancer,2006,9(4):325-328.
6. Kondo K, Miyoshi T, Hino N, et al. High frequency expressions of CD44 standard and variant forms in non-small cell lung cancers, but not in small cell lung cancers. J Surg Oncol, 1998,69(3):128-136.
7. Nguyen VN, Mirejovsky T, Melinova L, et al. CD44 and its v6 spliced variant in lung carcinomas: relation to NCAM, CEA, EMA and UP1 and prognostic significance. Neoplasma,2000,47(6): 400-408.
8. Shimbori M, Kijima H, Sato S, et al. Expression of CD44 in primary lung carcinomas using histological and cytological analyses. Anticancer Res,2003,23(1A):115-121.
9. Li YH, Gui SY, Zhou Q, et al. Relationship between osteopontin and CD44v6 expression and lung cancer metastasis. Tumor,2006, 26(1):55-58.
10. Fedarko NS, Jain A, Karadag A, et al. Elevated serum bone sialoprotein and osteopontin in colon, breast, prostate, and lung cancer. Clin Cancer Res,2001,7(12):4060-4066.
11. Katagiri YU, Sleeman J, Fujii H, et al. CD44 variants but not CD44s cooperate with beta1-containing integrins to permit cells to bind to osteopontin independently of arginine-glycine-aspartic acid, thereby stimulating cell motility and chemotaxis. Cancer Res, 1999,59(1):219-226.
12. Zohar R, Suzuki N, Suzuki K, et al. Intracellular osteopontin is an integral component of the CD44-ERM complex involved in cell migration. J Cell Physiol,2000,184(1):118-130.