Immunotherapy of human neuroblastoma using umbilical cord blood-derived effector cells

Journal of Neuroimmune Pharmacology

Volumn 2, Issue 2, 2007, Pages 202-212

  Joshi, Avadhut D ^a   Clark, Erin M ^a   Wang, Peng ^a   Munger, Corey M ^a   Hegde, Ganapati V ^a   Sanderson, Sam ^a   Dave, Harish P G ^b   Joshi, Shantaram S ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Cord blood; Cytotoxic T lymphocytes; Dendritic cells (DCs); LAK cells; Neuroblastoma

Indexed keywords

ANIMAL; ARTICLE; CELL CULTURE; CYTOLOGY; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; FETUS BLOOD; GLIOBLASTOMA; HUMAN; IMMUNOLOGY; IMMUNOTHERAPY; LYMPHOKINE ACTIVATED KILLER CELL; METHODOLOGY; MONONUCLEAR CELL; MOUSE; MOUSE MUTANT; NEUROBLASTOMA; TRANSPLANTATION; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CELLS, CULTURED; CYTOTOXICITY, IMMUNOLOGIC; FETAL BLOOD; GLIOBLASTOMA; HUMANS; IMMUNOTHERAPY; KILLER CELLS, LYMPHOKINE-ACTIVATED; LEUKOCYTES, MONONUCLEAR; MICE; MICE, SCID; NEUROBLASTOMA; T-LYMPHOCYTES, CYTOTOXIC;

EID: 34247534140     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-006-9038-y     Document Type: Article

References (45)

1. Apperley JF (1994) Umbilical cord blood progenitor cell transplantation, The International Conference Workshop on Cord Blood Transplantation, Indianapolis, November 1993. Bone Marrow Transplant 14:187-196
2. Azuma E, Hanada M, Masuda SI, Komada Y, Sakurai M (1990) Autologous tumor-specific cytotoxic T-lymphocytes in a child with neuroblastoma. Biomed Pharmacother 44:487-493
3. Bill AH (1969) The implications of immune reactions to neuroblastoma. Surgery 66:415-418
4. Bill AH, Morgan A (1970) Evidence for immune reactions to neuroblastoma and future possibilities for investigation. J Pediatr Surg 5:111-116
5. Bordow SB, Norris MD, Haber PS, Marshall GM, Haber M (1998) Prognostic significance of MYCN oncogene expression in childhood neuroblastoma. J Clin Oncol 16:3286-3294
6. Brodeur GM (2003) Neuroblastoma: biological insights into a clinical enigma. Nat Rev Cancer 3:203-216
7. Brodeur GM, Seeger RC, Schwab M, Varmus HE, Bishop JM (1984) Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science 224: 1121-1124
8. Broxmeyer HE, Gluckman E, Auerbach A, Douglas GW, Friedman H, Cooper S, Hangoc G, Kurtzberg J, Bard J, Boyse E A (1990) Human umbilical cord blood: a clinically useful source of transplantable hematopoietic stem/progenitor cells. Int J Cell Cloning 8(Suppl 1):76-89; discussion 89-91
9. Cairo MS, Wagner .IE (1997) Placental and/or umbilical cord blood: an alternative source of hematopoietic stem cells for transplantation. Blood 90:4665-4678
10. Foreman NK, Rill DR, Coustan-Smith E, Douglass EC, Brenner MK (1993) Mechanisms of selective killing of neuroblastoma cells by natural killer cells and lymphokine activated killer cells. Potential for residual disease eradication. Br .1 Cancer 67:933-938
11. Gardner JD, Liechty KW, Christensen RD (1990) Effects of interleukin-6 on fetal hematopoietic progenitors. Blood 75: 2150-2155
12. Gluckman E, Broxmeyer HA, Auerbach AD, Friedman HS, Douglas GW, Devergie A, Esperou H, Thierry D, Socie G, Lehn P (1989) Hematopoietic reconstitution in a patient with Fanconi's anemia by means of umbilical-cord blood from an HLA-identical sibling. N Engl J Med 321:1174-1178
13. Grovas A, Fremgen A, Rauck A, Ruymann FB, Hutchinson CL, Winchester DP, Menck HR (1997) The National Cancer Data Base report on patterns of childhood cancers in the United States. Cancer 80:2321-2332
14. Gurney JG, Ross JA, Wall DA, Bleyer WA, Severson RK, Robison LL (1997) Infant cancer in the US: histology-specific incidence and trends, 1973 to 1992. J Pediatr Hematol Oncol 19: 428-432
15. Harris DT (1995) In vitro and In vivo assessment of the graft-versusleukemia activity of cord blood. Bone Marrow Transplant 15:17-23
16. Harris DT, Schumacher MJ, LoCascio J, Booth A, Bard J, Boyse EA (1994) Immunoreactivity of umbilical cord blood and post-partum maternal peripheral blood with regard to HLA-haploidentical transplantation. Bone Marrow Transplant 14:63-68
17. Hellstrom IE, Hellstrom KE, Pierce GE, Bill AH (1968) Demonstration of cell-bound and humoral immunity against neuroblastoma cells. Proc Natl Acad Sci USA 60:1231-1238
18. Inoue M, Nakano T, Yoneda A, Nishikawa M, Nakayama M, YumuraYagi K., Sakata N, Yasui M, Okamura T, Kawa K (2003) Graftversus-tumor effect in a patient with advanced neuroblastoma who received HLA haplo-identical bone marrow transplantation. Bone Marrow Transplant 32:103-106
19. Jarnjak-Jankovic S, Pettersen RD, Saeboe-Larssen S, Wesenberg F, Olafsen MR, Gaudernack G (2005) Preclinical evaluation of autologous dendritic cells transfected with mRNA or loaded with apoptotic cells for immunotherapy of high-risk neuroblastoma. Cancer Gene Ther 12:699-707
20. Joshi SS, Babushkina-Patz NN, Verbik DJ, Gross TG, Tarantolo SR, Kuszynski CA, Pirruccello SJ, Bishop MR, Kessinger A (1998) Antitumor activity of human umbilical cord blood cells: a comparative analysis with peripheral blood and bone marrow cells. Int J Oncol 13:791-799
21. Joshi SS, Tarantolo SR, Kuszynski CA, Kessinger A (2000) Antitumor therapeutic potential of activated human umbilical cord blood cells against leukemia and breast cancer. Clin Cancer Res 6:4351-4358
22. Joshi SS, Vu UE, Lovgren TR, Lorkovic M, Patel W, Todd GL, Kuszynski C, Joshi BJ, Dave HP (2002) Comparison of phenotypic and functional dendritic cells derived from human umbilical cord blood and peripheral blood mononuclear cells. J Hematother Stem Cell Res 11:337-347
23. Katzenstein HM, Bowman LC, Brodeur GM, Thorner PS, Joshi VV, Smith El, Look AT, Rowe ST, Nash MB, Holbrook T, Alvarado C, Rao PV, Castleberry RP, Cohn SL (1998) Prognostic significance of age, MYCN oncogene amplification, tumor cell ploidy, and histology in 110 infants with stage D(S) neuroblastoma: the pediatric oncology group experience - a pediatric oncology group study. J Clin Oncol 16:2007-2017
24. Kessinger A, Armitage JO (1991) The evolving role of autologous peripheral stem cell transplantation following high-dose therapy for malignancies. Blood 77:211-213
25. Maher EA, Furnari FB, Bachoo RM, Rowitch DH, Louis DN, Cavenee WK, DePinho RA (2001) Malignant glioma: genetics and biology of a grave matter. Genes Dev 15:1311-1333
26. Main EK, Lampson LA, Hart MK, Kornbluth J, Wilson DB (1985) Human neuroblastoma cell lines are susceptible to lysis by natural killer cells but not by cytotoxic T lymphocytes. J Immunol 135:242-246
27. Main EK, Monos DS, Lampson LA (1988) IFN-treated neuroblastoma cell lines remain resistant to T cell-mediated allo-killing, and susceptible to non-MHC-restricted cytotoxicity. J Immunol 141:2943-2950
28. Maris JM, Matthay KK (1999) Molecular biology of neuroblastoma. J Clin Oncol 17:2264-2279
29. Negrier S, Michon J, Floret D, Bouffet E, Gentet JC, Philip I, Cochat P, Stamm D, Costil J, Gaspard M (1991) lnterleukin-2 and lymphokine-activated killer cells in 15 children with advanced metastatic neuroblastoma. J Clin Oncol 9:1363-1370
30. Piacibello W, Ferrero D, Sanavio F, Badoni R, Stacchini A, Severino A, Aglietta M (1991) Responsiveness of highly enriched CFU-GM subpopulations from bone marrow, peripheral blood, and cord blood to hemopoietic growth inhibitors. Exp Hematol 19:1084-1089
31. Riley RD, Heney D, Jones DR, Sutton AJ, Lambert PC, Abrams KR, Young B, Wailoo AJ, Burchill SA (2004) A systematic review of molecular and biological tumor markers in neuroblastoma. Clin Cancer Res 10:4-12
32. Rossi AR, Pericle F, Rashleigh S, Janiec J, Djeu JY (1994) Lysis of neuroblastoma cell lines by human natural killer cells activated by interleukin-2 and interleukin-12. Blood 83:1323-1328
33. Schoemans H, Theunissen K, Maertens J, Boogaerts M, Verfaillie C, Wagner J (2006) Adult umbilical cord blood transplantation: a comprehensive review. Bone Marrow Transplant 38:83-93
34. Schwab M (2004) MYCN in neuronal tumours. Cancer Lett 204:179-187
35. Seeger RC, Brodeur GM, Sather H, Dalton A, Siegel SE, Wong KY, Hammond D (1985) Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas. N Engl J Med 313:1111-1116
36. Sivori S, Parolini S, Marcenaro E, Castriconi R, Pende D, Millo R, Moretta A (2000) Involvement of natural cytotoxicity receptors in human natural killer cell-mediated lysis of neuroblastoma and glioblastoma cell lines. .1 Neuroimmunol 107:220-225
37. Stram DO, Matthay KK, O'Leary M, Reynolds CP, Haase QM, Atkinson JB, Brodeur GM, Seeger RC (1996) Consolidation chemoradiotherapy and autologous bone marrow transplantation versus continued chemotherapy for metastatic neuroblastoma: a report of two concurrent Children's Cancer Group studies. J Clin Oncol 14:2417-2426
38. Tanaka T, Iehara T, Sugimoto T, Hamasaki M, Teramukai S, Tsuchida Y, Kaneko M, Sawada T (2005) Diversity in neuroblastomas and discrimination of the risk to progress. Cancer Lett 228:267-270
39. Valteau-Couanet D, Leboulaire C, Maincent K, Toumier M, Hartmann O, Benard J, Beaujean F, Boccaccio C, Zitvogel L, Angevin E (2002) Dendritic cells for NK/LAK activation: rationale for multicellular immunotherapy in neuroblastoma patients. Blood 100:2554-2561
40. Verbik DJ, Jackson JD, Pirruccello SJ, Patil KD, Kessinger A, Joshi SS (1995) Functional and phenotypic characterization of human peripheral blood stem cell harvests: a comparative analysis of cells from consecutive collections. Blood 85:1964-1970
41. Verneris MR, Brunstein C, DeFor TE, Barker J, Weisdorf DJ, Blazar BR, Miller JS, Wagner JE (2005) Risk of relapse (REL) after umbilical cord blood transplantation (UCBT) in patients with acute leukemia: marked reduction in recipients of two units. Blood (ASH Annual Meeting Abstracts) 106:305
42. Wagner JE, Broxmeyer HE, Byrd RL, Zehnbauer B, Schmeckpeper B, Shah N, Griffin C, Emanuel PD, Zuckerman KS, Cooper S (1992) Transplantation of umbilical cord blood after myeloablative therapy: analysis of engraftment. Blood 79:1874-1881
43. Wang P, Munger CM, Joshi AD, Pirruccello SJ, Joshi SS (2004) Cytotoxicity of cord blood derived Her2/neu-specific cytotoxic T lymphocytes against human breast cancer in vitro and in vivo. Breast Cancer Res Treat 83:15-23
44. Weinstein JL, Katzenstein HM, Cohn SL (2003) Advances in the diagnosis and treatment of neuroblastoma. Oncologist 8:278-292
45. Wiktor-Jedrzejczak W, Rokicka M, Urbanowska E, Torosjan T, Gronkowska A, Graczyk-Pol E, Tomaszewska A, Paluszewska M, Tormanowska M, Krol M, Krol M, Jolkowska J, Witt M (2005) Simultaneous transplantation of three cord blood units in adults with high risk acute leukemia. Blood (ASH Annual Meeting Abstracts) 106:5457