Malignant lymphomas in the elderly: A single institute experience highlights future directions

Archives of Gerontology and Geriatrics

Volumn 45, Issue 1, 2007, Pages 43-53

  Váróczy, László ^a   Dankó, Alpár ^a   Simon, Zsófia ^a   Gergely, Lajos ^a   Ress, Zsuzsa ^a   Illés, Árpád ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

Chemotherapy; Comorbidity; Hodgkin's lymphoma; Non Hodgkin's lymphoma; Remission results; Survival rates

Indexed keywords

AGED; ARTICLE; B CELL LYMPHOMA; CANCER PATIENT; CANCER REGRESSION; CANCER STAGING; CANCER SURVIVAL; COMORBIDITY; CONTROLLED STUDY; ELDERLY CARE; FEMALE; GERIATRIC PATIENT; HODGKIN DISEASE; HUMAN; MAJOR CLINICAL STUDY; MALE; NONHODGKIN LYMPHOMA; OVERALL SURVIVAL; PRIORITY JOURNAL; SURVIVAL RATE;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGE FACTORS; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; CHILD; DIAGNOSIS, DIFFERENTIAL; DISEASE PROGRESSION; FEMALE; HUMANS; HUNGARY; INCIDENCE; LYMPHOMA; MALE; MIDDLE AGED; PRACTICE GUIDELINES; REMISSION INDUCTION; RETROSPECTIVE STUDIES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SURVIVAL RATE;

EID: 34247523830     PISSN: 01674943     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.archger.2006.08.001     Document Type: Article

References (36)

1. Ania B.J., Suman V.J., Fairbanks V.F., Rademacher D.M., and Melton L.J. Incidence of anaemia in older people: an epidemiologic study in a well defined population. J. Am. Geriatr. Soc. 45 (1997) 825-831
2. Baker S.D., and Grochow L.B. Pharmacology of cancer chemotherapy in the older person. Clin. Geriatr. Med. 13 (1997) 169-183
3. Balducci L., and Extremann M. Management of cancer in the older person: a practical approach. Oncologist 5 (2000) 224-237
4. Balducci L., and Repetto L. Increased risk of myelotoxicity in elderly patients with non-Hodgkin lymphoma. Cancer 100 (2004) 6-11
5. Balducci L., and Yates J. General guidelines for the management of older patients with cancer. Oncology 14 (2000) 221-227
6. Baris D., and Zahm S.H. Epidemiology of lymphomas. Curr. Opin. Oncol. 12 (2000) 383-394
7. Chen-Hardee S., Chrischilles E.A., Voelker M.D., Brooks J.M., Scott S., Link B.K., and Delgado D. Population-based assessment of hospitalizations for neutropenia from chemotherapy in older adults with non-Hodgkin's lymphoma (United States). Cancer Causes Control 17 (2006) 647-654
8. Cordoba S., Romero J., De la Torre A., Valcarcel F., Magallan R., Regueiro C.A., and Garcia-Berrocal M.I. Early stage infradiaphragmatic Hodgkin's disease: results of radiotherapy and review of the literature. Radiother. Oncol. 67 (2003) 259-263
9. Engert A., Ballova V., Haverkamp H., Pfistner B., Josting A., Duhmke E., Müller-Hermelink K., and Diehl V. Hodgkin's lymphoma in elderly patients: a comprehensive retrospective analysis from the German Hodgkin's Study Group. J. Clin. Oncol. 23 (2005) 5052-5060
10. Epelbaum R., Faragi D., and Ben-Arie Y. Survival of diffuse large cell lymphoma. A multivariate analysis including dose intensity variables. Cancer 66 (1990) 1124-1129
11. Extermann M., Overcash J., Lyman G.H., Parr J., and Balducci L. Comorbidity and functional status are independent in older cancer patients. J. Clin. Oncol. 16 (1998) 1582-1588
12. Fried L.P., Tangen C.M., Walston J., Newman A.B., Hirsch C., Gottdiener J., Seeman T., Tracy R., Kop W.J., Burke G., and McBurnie M.A. Frailty in older adults: evidence for a phenotype. J. Gerontol. A Biol. Sci. Med. Sci. 56 (2001) M146-M156
13. Gutman J.A., Bearman S.I., Nieto Y., Sweetenham J.W., Jones R.B., Shapall E.J., Zeng C., Baron A., and McSweeney P.A. Autologous transplantation followed closely by reduced-intensity allogeneic transplantation as consolidative immunotherapy in advenced lymphoma patients: a feasibility study. Bone Marrow Transplant. 36 (2005) 443-451
14. Harousseau J.L., Shaugnessy J., and Richardson P. Multiple myeloma. Hematology (2004) 237-256
15. Harris N.L., Jaffe E.S., and Stein H. A revised European-American classification of lymphoid neoplasms. A proposal from the International Lymphoma Study Group. Blood 84 (1994) 1361-1392
16. Harris N.L., Jaffe E.S., and Diebold J. The World Health Organization Classification of Neoplastic Diseases of the Haematopoietic and Lymphoid Tissues: Report of the Clinical Advisory Committee Meeting. Airlie House, Virginia, November 1997. Histopathology 36 (2000) 69-89
17. Heinrich B. Therapeutic outcomes in systemic lymphatic diseases and plasmocytoma. New hope for palliative patients. M. M. W. Fortschr. Med. 147 (2005) 23
18. Hiddemann W., Buske C., Dreyling M., Weigert O., Lenz G., Forstpointner R., Nickenig C., and Unterhalt M. Treatment strategies in follicular lymphomas: current status and future perspectives. J. Clin. Oncol. 23 (2005) 6394-6399
19. Illés A., Vadász G., Gergely L., and Szegedi G. Hodgkin's disease in the elderly: a single institution retrospective study of 40 patients aged 65 or over. Haematologia 30 (2000) 263-269
20. Italiano A., Jardin F., Peyrade F., Saudes S., Tilly H., and Thyss A. Adopted CHOP plus rituximab in non Hodgkin's lymphoma in patients over 80 years old. Haematologica 90 (2005) 1281-1283
21. Jabbour E., Chalhoub B., Suzan F., Aloulou S., Cainap C., Toumi N., Fermé C., Carde P., and Ribrag V. Outcome of elderly patients with agressive non-Hodgkin's lymphoma refractory to or relapsing after first line CHOP or CHOP-like chemotherapy: a low probability of cure. Leuk. Lymphoma 45 (2004) 1391-1394
22. Kourokis C.T., Browman G.P., Esmail R., and Meyer R.M. Chemotherapy for older patients with newly diagnosed, advenced-stage, agressive-histology non-Hodgkin lymphoma: a systemic review. Ann. Intern. Med. 136 (2002) 144-152
23. Lee K.W., Kim D.Y., Yun T., Kim D.W., Kim T.Y., Yoon S.S., Heo D.S., Bang Y.J., Park S., Kim B.K., and Kim N.K. Doxorubicin-based chemotherapy for diffuse large B-cell lymphoma in elderly patients. Cancer 98 (2003) 2651-2656
24. Levis A., Anselmo A.P., and Ambrosetti A. VEPEMB chemotherapy in elderly Hodgkin's disease patients. Leuk. Lymphoma 42 (2001) 104
25. Maartense E., Kluin-Nelemans H.C., le Cessie S., Kluin P.M., Snijder S., and Noordijk E.M. Different age limits for elderly patients with indolent and aggressive non-Hodgkin lymphoma and the role of relative survival with increasing age. Cancer 89 (2000) 2667-2676
26. Maartense K., Kluin-Nelemans H.C., and Noordijk E.M. Non-Hodgkin's lymphoma of the elderly. Ann. Hematol. 82 (2003) 661-670
27. Osterborg A., Brandberg Y., Molostava G., Iosava G., Abdulkadyrov K., Hedenus M., Messinger D., and Epoetin Beta Hematology Study Group. Randomized, double-blind, placebo controlled trial of recombinant human erythropoetin, epoetin beta, in hematologic malignancies. J. Clin. Oncol. 20 (2002) 2486-2494
28. Peters F.P., Fickers M.M., Erdkamp F.L., Wals J., Wils J.A., and Schouten H.C. The effect of optimal treatment on elderly patients with aggressive non-Hodgkin's lymphoma: more patients treated with unaffected response rates. Ann. Hematol. 80 (2001) 406-410
29. Polliack A. Hairy cell leukaemia and allied chronic lymphoid leukaemias: current knowledge and new therapeutic options. Leuk. Lymphoma 26 (1997) 41-51
30. Proctor S.J., Rueffer J.U., Angus B., Breuer K., Flechtner H., Jarret R., Levis A., Taylor P., and Tirelli U. Hodgkin's disease in the elderly: current status and future directions. Ann. Oncol. 13 (2002) 133-137
31. Proctor S.J., White J., and Jones G.L. An international approach to the treatment of Hodgkin's disease in the elderly: launch of the SHIELD study programme. Eur. J. Hematol. Suppl. 66 (2005) 63-67
32. Rao A.V., Akabani G., and Rizziera D.A. Radioimmunotherapy for non-Hodgkin's lymphoma. Clin. Med. Res. 3 (2005) 157-165
33. Robak T. Therapy of chronic lymphocytic leukaemia with purine nucleoside analogues: facts and contoversies. Drugs Aging 22 (2005) 983-1012
34. Tirelli U., Carbone A., Monfardini S., and Zagonel V. A 20-year experience on malignant lymphomas in patients aged 70 and older at a single institute. Crit. Rev. Oncol. Hematol. 37 (2001) 153-158
35. Wasil T., and Lichtman S.M. Clinical pharmacology issues relevant to the dosing and toxicity of chemotherapy drugs in the elderly. Oncologist 10 (2005) 602-612
36. Zacchariah B., Balducci L., Venkattaramanabalaji G.V., Casey L., Greenberg H.M., and DelRegato J.A. Radiotherapy for cancer patients aged 80 and older: a study of effectiveness and side effects. Int. J. Radiat. Oncol. Biol. Phys. 39 (1997) 1125-1129