Thyrotoxic autoimmune encephalopathy in a female patient: Only partial response to typical immunosuppressant treatment and remission after thyroidectomy

Clinical Neurology and Neurosurgery

Volumn 109, Issue 5, 2007, Pages 458-462

  Yuceyar, Nur ^a   Karadeniz, Muammer ^a   Erdogan, Mehmet ^a   Copur, Asli ^a   Akgun, Aysegul ^a   Kumral, Emre ^a   Ozgen, Gokhan ^a  

^a EGE UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

Author keywords

Autoimmune; Encephalopathy; Family history; Genetic; Hashimoto's; Thyroiditis; Thyrotoxicosis

Indexed keywords

AZATHIOPRINE; IMMUNOGLOBULIN; LEVOTHYROXINE; METHYLPREDNISOLONE; METOPROLOL; PREDNISOLONE; PROPYLTHIOURACIL; THYROID ANTIBODY;

ADULT; ANTIBODY BLOOD LEVEL; ARTICLE; AUTOIMMUNE DISEASE; CASE REPORT; ECHOGRAPHY; FEMALE; GENETIC TRAIT; HASHIMOTO DISEASE; HASHIMOTO ENCEPHALOPATHY; HUMAN; PLASMAPHERESIS; REMISSION; THYROIDECTOMY;

ADULT; AUTOANTIBODIES; AUTOANTIGENS; BRAIN DISEASES; DIAGNOSIS, DIFFERENTIAL; FEMALE; HASHIMOTO DISEASE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INFUSIONS, INTRAVENOUS; IODIDE PEROXIDASE; IRON-BINDING PROTEINS; METHYLPREDNISOLONE; RECURRENCE; THYROGLOBULIN; THYROIDECTOMY; THYROTOXICOSIS;

EID: 34247500895     PISSN: 03038467     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clineuro.2007.02.006     Document Type: Article

References (18)

1. Shaw P.J., Walls T.J., Newman P.K., et al. Hashimoto's encephalopathy: a steroid responsive disorder associated with high anti-thyroid antibody titers-report of 5 cases. Neurology 41 (1991) 228-233
2. Chong J.Y., Rowland L.P., and Utiger R.D. Hashimoto's encephalopathy: syndrome or myth?. Arch Neurol 60 2 (2003) 164-171
3. Ferracci F., and Carnevale A. The neurological disorder associated with thyroid autoimmunity. J Neurol 253 8 (2006) 975-984
4. Castillo P., Woodruff B., Caselli R., et al. Steroid responsive encephalopathy associated with autoimmune thyroiditis. Arch Neurol 63 2 (2006) 175-176
5. Ochi H., Horiuchi I., Araki N., et al. Proteomic analysis of human brain identifies α-enolase as a novel autoantigen in Hashimoto's encephalopathy. FEBS Lett. 528 (2002) 197-202
6. Forchetti C., Katsamakis G., and Garron D.C. Autoimmune thyroiditis and rapidly progressive dementia: global hypoperfusion on SPECT scanning suggests a possible mechanism. Neurology 49 2 (1997) 623-626
7. Oide T., Tokuda T., Yazaki M., et al. Anti-neuronal autoantibody in Hashimoto's encephalopathy: neuropathological, immunohistochemical, and biochemical analysis of two patients. J Neurol Sci 217 (2004) 7-12
8. Barker R., Zajicek J., and Wilkinson I. Thyrotoxic Hashimoto's encephalopathy. J Neurol Neurosurg Psychiatry 60 (1996) 234
9. Canton A., de Fabregas O., Tintore M., et al. Encephalopathy associated to autoimmune thyroid disease: a more appropriate term for an underestimated condition?. J Neurol Sci 176 (2000) 65-69
10. Seo S.W., Lee B.I., Lee J.D., et al. Thyrotoxic autoimmune encephalopathy: a repeat positron emission tomography study. J Neurol Neurosurg Psychiatry 74 (2003) 504-506
11. Primavera A., Brusa G., and Novello P. Thyrotoxic encephalopathy and recurrent seizures. Eur Neurol 30 (1990) 186-188
12. Jabbari B., and Huott A.D. Seizures in thyrotoxicosis. Epilepsia 21 1 (1980) 91-96
13. Li Voon Chong J.S., Lecky B.R., and Macfarlane I.A. Recurrent encephalopathy and generalized seizures associated with relapses of thyrotoxicosis. Int J Clin Pract 54 9 (2000) 621-622
14. Smith D.L., and Looney T.J. Seizures secondary to thyrotoxicosis and high dose propronolol therapy. Arch Neurol 40 (1983) 457-458
15. Takahashi S., Mitamura R., Itoh Y., et al. Hashimoto's encephalopathy: etiologic considerations. Pediatr Neurol 11 4 (1994) 328-331
16. Dittmar M., and Kahaly G.J. Immunregulatory and susceptibility genes in thyroid and polyglandular autoimmunity. Thyroid 15 3 (2005) 239-250
17. Levin L., Ban Y., Concepsion E., et al. Analysis of HLA genes in families with autoimmune diabetes and thyroiditis. Hum Immunol 65 6 (2004) 640-647
18. Segni M., Wood J., Pucarelli I., et al. Clustering of autoimmune thyroid disease in children and adolescents: a study of 66 families. J Pediatr Endocrinol Metab 14 Suppl. 5 (2001) 1271-1275