Synthesis, characterization and in vitro cytotoxicity studies of a macromolecular conjugate of paclitaxel bearing oxytocin as targeting moiety

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 66, Issue 2, 2007, Pages 182-192

  Cavallaro, Gennara ^a   Maniscalco, Laura ^a   Campisi, Monica ^a   Schillaci, Domenico ^a   Giammona, Gaetano ^a  

^a UNIVERSITY OF PALERMO   (Italy)

Author keywords

Bioconjugate; Drug targeting; Oxytocin; Paclitaxel; Polyaspartamide

Indexed keywords

AMIDE; OXYTOCIN; PACLITAXEL; POLYASPARTAMIDE; PRODRUG; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN MCF 7; CONJUGATE; CYTOTOXICITY; DRUG ANALYSIS; DRUG CONJUGATION; DRUG EFFECT; DRUG RELEASE; DRUG STABILITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; MACROMOLECULE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; DRUG COMPOUNDING; DRUG STABILITY; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; MOLECULAR STRUCTURE; OXYTOCIN; PACLITAXEL; PEPTIDES; POLYETHYLENE GLYCOLS; PRODRUGS; RECEPTORS, OXYTOCIN; SOLUBILITY; TIME FACTORS;

EID: 34247493695     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2006.10.013     Document Type: Article

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