메뉴 건너뛰기




Volumn 153, Issue 2, 2007, Pages 207-212

Nuclear run-on analysis of var gene expression in Plasmodium falciparum

Author keywords

Malaria; Nuclear run on; var gene

Indexed keywords

RNA POLYMERASE II;

EID: 34247492195     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2007.02.004     Document Type: Article
Times cited : (23)

References (42)
  • 1
    • 15044338866 scopus 로고    scopus 로고
    • The global distribution of clinical episodes of Plasmodium falciparum malaria
    • Snow R.W., Guerra C.A., Noor A.M., Myint H.Y., and Hay S.I. The global distribution of clinical episodes of Plasmodium falciparum malaria. Nature 434 (2005) 214-217
    • (2005) Nature , vol.434 , pp. 214-217
    • Snow, R.W.1    Guerra, C.A.2    Noor, A.M.3    Myint, H.Y.4    Hay, S.I.5
  • 2
    • 1642431673 scopus 로고    scopus 로고
    • var genes, PfEMP1 and the human host
    • Flick K., and Chen Q. var genes, PfEMP1 and the human host. Mol Biochem Parasitol 134 (2004) 3-9
    • (2004) Mol Biochem Parasitol , vol.134 , pp. 3-9
    • Flick, K.1    Chen, Q.2
  • 3
    • 25644458281 scopus 로고    scopus 로고
    • The immunology and pathogenesis of malaria during pregnancy
    • Beeson J.G., and Duffy P.E. The immunology and pathogenesis of malaria during pregnancy. Curr Top Microbiol Immunol 297 (2005) 187-227
    • (2005) Curr Top Microbiol Immunol , vol.297 , pp. 187-227
    • Beeson, J.G.1    Duffy, P.E.2
  • 5
    • 0029052741 scopus 로고
    • Cloning the P. falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytes
    • Baruch D.I., Pasloske B.L., Singh H.B., et al. Cloning the P. falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytes. Cell 82 (1995) 77-87
    • (1995) Cell , vol.82 , pp. 77-87
    • Baruch, D.I.1    Pasloske, B.L.2    Singh, H.B.3
  • 6
    • 0028982168 scopus 로고
    • Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes
    • Smith J.D., Chitnis C.E., Craig A.G., et al. Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes. Cell 82 (1995) 101-110
    • (1995) Cell , vol.82 , pp. 101-110
    • Smith, J.D.1    Chitnis, C.E.2    Craig, A.G.3
  • 7
    • 0029070914 scopus 로고
    • The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of Plasmodium falciparum-infected erythrocytes
    • Su X.Z., Heatwole V.M., Wertheimer S.P., et al. The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of Plasmodium falciparum-infected erythrocytes. Cell 82 (1995) 89-100
    • (1995) Cell , vol.82 , pp. 89-100
    • Su, X.Z.1    Heatwole, V.M.2    Wertheimer, S.P.3
  • 8
    • 0037015614 scopus 로고    scopus 로고
    • Genome sequence of the human malaria parasite Plasmodium falciparum
    • Gardner M.J., Hall N., Fung E., et al. Genome sequence of the human malaria parasite Plasmodium falciparum. Nature 419 (2002) 498-511
    • (2002) Nature , vol.419 , pp. 498-511
    • Gardner, M.J.1    Hall, N.2    Fung, E.3
  • 9
    • 0032560859 scopus 로고    scopus 로고
    • Developmental selection of var gene expression in Plasmodium falciparum
    • Chen Q., Fernandez V., Sundstrom A., et al. Developmental selection of var gene expression in Plasmodium falciparum. Nature 394 (1998) 392-395
    • (1998) Nature , vol.394 , pp. 392-395
    • Chen, Q.1    Fernandez, V.2    Sundstrom, A.3
  • 10
    • 0032530397 scopus 로고    scopus 로고
    • Antigenic variation in malaria: in situ switching, relaxed and mutually exclusive transcription of var genes during intra-erythrocytic development in Plasmodium falciparum
    • Scherf A., Hernandez-Rivas R., Buffet P., et al. Antigenic variation in malaria: in situ switching, relaxed and mutually exclusive transcription of var genes during intra-erythrocytic development in Plasmodium falciparum. EMBO J 17 (1998) 5418-5426
    • (1998) EMBO J , vol.17 , pp. 5418-5426
    • Scherf, A.1    Hernandez-Rivas, R.2    Buffet, P.3
  • 11
    • 20144389848 scopus 로고    scopus 로고
    • Heterochromatin silencing and locus repositioning linked to regulation of virulence genes in Plasmodium falciparum
    • Duraisingh M.T., Voss T.S., Marty A.J., et al. Heterochromatin silencing and locus repositioning linked to regulation of virulence genes in Plasmodium falciparum. Cell 121 (2005) 13-24
    • (2005) Cell , vol.121 , pp. 13-24
    • Duraisingh, M.T.1    Voss, T.S.2    Marty, A.J.3
  • 12
    • 20144389331 scopus 로고    scopus 로고
    • Telomeric heterochromatin propagation and histone acetylation control mutually exclusive expression of antigenic variation genes in malaria parasites
    • Freitas-Junior L.H., Hernandez-Rivas R., Ralph S.A., et al. Telomeric heterochromatin propagation and histone acetylation control mutually exclusive expression of antigenic variation genes in malaria parasites. Cell 121 (2005) 25-36
    • (2005) Cell , vol.121 , pp. 25-36
    • Freitas-Junior, L.H.1    Hernandez-Rivas, R.2    Ralph, S.A.3
  • 13
    • 17244382283 scopus 로고    scopus 로고
    • Antigenic variation in Plasmodium falciparum is associated with movement of var loci between subnuclear locations
    • Ralph S.A., Scheidig-Benatar C., and Scherf A. Antigenic variation in Plasmodium falciparum is associated with movement of var loci between subnuclear locations. Proc Natl Acad Sci USA 102 (2005) 5414-5419
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 5414-5419
    • Ralph, S.A.1    Scheidig-Benatar, C.2    Scherf, A.3
  • 14
    • 0141483283 scopus 로고    scopus 로고
    • Plasmodium falciparum var genes are regulated by two regions with separate promoters, one upstream of the coding region and a second within the intron
    • Calderwood M.S., Gannoun-Zaki L., Wellems T.E., and Deitsch K.W. Plasmodium falciparum var genes are regulated by two regions with separate promoters, one upstream of the coding region and a second within the intron. J Biol Chem 278 (2003) 34125-34132
    • (2003) J Biol Chem , vol.278 , pp. 34125-34132
    • Calderwood, M.S.1    Gannoun-Zaki, L.2    Wellems, T.E.3    Deitsch, K.W.4
  • 15
    • 13844306877 scopus 로고    scopus 로고
    • A silenced Plasmodium falciparum var promoter can be activated in vivo through spontaneous deletion of a silencing element in the intron
    • Gannoun-Zaki L., Jost A., Mu J., Deitsch K.W., and Wellems T.E. A silenced Plasmodium falciparum var promoter can be activated in vivo through spontaneous deletion of a silencing element in the intron. Eukaryot Cell 4 (2005) 490-492
    • (2005) Eukaryot Cell , vol.4 , pp. 490-492
    • Gannoun-Zaki, L.1    Jost, A.2    Mu, J.3    Deitsch, K.W.4    Wellems, T.E.5
  • 16
    • 33744524946 scopus 로고    scopus 로고
    • Strict pairing of var promoters and introns is required for var gene silencing in the malaria parasite Plasmodium falciparum
    • Frank M., Dzikowski R., Costantini D., Amulic B., Berdougo E., and Deitsch K. Strict pairing of var promoters and introns is required for var gene silencing in the malaria parasite Plasmodium falciparum. J Biol Chem 281 (2006) 9942-9952
    • (2006) J Biol Chem , vol.281 , pp. 9942-9952
    • Frank, M.1    Dzikowski, R.2    Costantini, D.3    Amulic, B.4    Berdougo, E.5    Deitsch, K.6
  • 17
    • 33644551229 scopus 로고    scopus 로고
    • A var gene promoter controls allelic exclusion of virulence genes in Plasmodium falciparum malaria
    • Voss T.S., Healer J., Marty A.J., et al. A var gene promoter controls allelic exclusion of virulence genes in Plasmodium falciparum malaria. Nature 439 (2006) 1004-1008
    • (2006) Nature , vol.439 , pp. 1004-1008
    • Voss, T.S.1    Healer, J.2    Marty, A.J.3
  • 18
    • 0033971074 scopus 로고    scopus 로고
    • A simple RNA analysis method shows var and rif multigene family expression patterns in Plasmodium falciparum
    • Kyes S., Pinches R., and Newbold C. A simple RNA analysis method shows var and rif multigene family expression patterns in Plasmodium falciparum. Mol Biochem Parasitol 105 (2000) 311-315
    • (2000) Mol Biochem Parasitol , vol.105 , pp. 311-315
    • Kyes, S.1    Pinches, R.2    Newbold, C.3
  • 19
    • 0038820121 scopus 로고    scopus 로고
    • A well-conserved Plasmodium falciparum var gene shows an unusual stage-specific transcript pattern
    • Kyes S.A., Christodoulou Z., Raza A., et al. A well-conserved Plasmodium falciparum var gene shows an unusual stage-specific transcript pattern. Mol Microbiol 48 (2003) 1339-1348
    • (2003) Mol Microbiol , vol.48 , pp. 1339-1348
    • Kyes, S.A.1    Christodoulou, Z.2    Raza, A.3
  • 20
    • 0036227659 scopus 로고    scopus 로고
    • Transcription of multiple var genes by individual, trophozoite-stage Plasmodium falciparum cells expressing a chondroitin sulphate A binding phenotype
    • Duffy M.F., Brown G.V., Basuki W., et al. Transcription of multiple var genes by individual, trophozoite-stage Plasmodium falciparum cells expressing a chondroitin sulphate A binding phenotype. Mol Microbiol 43 (2002) 1285-1293
    • (2002) Mol Microbiol , vol.43 , pp. 1285-1293
    • Duffy, M.F.1    Brown, G.V.2    Basuki, W.3
  • 21
    • 3042642153 scopus 로고    scopus 로고
    • Sub-grouping of Plasmodium falciparum 3D7 var genes based on sequence analysis of coding and non-coding regions
    • Lavstsen T., Salanti A., Jensen A.T., Arnot D.E., and Theander T.G. Sub-grouping of Plasmodium falciparum 3D7 var genes based on sequence analysis of coding and non-coding regions. Malar J 2 (2003) 27
    • (2003) Malar J , vol.2 , pp. 27
    • Lavstsen, T.1    Salanti, A.2    Jensen, A.T.3    Arnot, D.E.4    Theander, T.G.5
  • 22
    • 0347517765 scopus 로고    scopus 로고
    • Evidence for the importance of genetic structuring to the structural and functional specialization of the Plasmodium falciparum var gene family
    • Kraemer S.M., and Smith J.D. Evidence for the importance of genetic structuring to the structural and functional specialization of the Plasmodium falciparum var gene family. Mol Microbiol 50 (2003) 1527-1538
    • (2003) Mol Microbiol , vol.50 , pp. 1527-1538
    • Kraemer, S.M.1    Smith, J.D.2
  • 23
    • 33847643223 scopus 로고    scopus 로고
    • Patterns of gene recombination shape var gene repertoires in Plasmodium falciparum: comparison of geographically diverse isolates
    • Kraemer S.M., Kyes S.A., Aggarwal G., et al. Patterns of gene recombination shape var gene repertoires in Plasmodium falciparum: comparison of geographically diverse isolates. BMC Genom 8 (2007) 45
    • (2007) BMC Genom , vol.8 , pp. 45
    • Kraemer, S.M.1    Kyes, S.A.2    Aggarwal, G.3
  • 24
    • 8644292712 scopus 로고    scopus 로고
    • Evidence for the involvement of VAR2CSA in pregnancy-associated malaria
    • Salanti A., Dahlback M., Turner L., et al. Evidence for the involvement of VAR2CSA in pregnancy-associated malaria. J Exp Med 200 (2004) 1197-1203
    • (2004) J Exp Med , vol.200 , pp. 1197-1203
    • Salanti, A.1    Dahlback, M.2    Turner, L.3
  • 25
    • 0038046769 scopus 로고    scopus 로고
    • Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria
    • Salanti A., Staalsoe T., Lavstsen T., et al. Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria. Mol Microbiol 49 (2003) 179-191
    • (2003) Mol Microbiol , vol.49 , pp. 179-191
    • Salanti, A.1    Staalsoe, T.2    Lavstsen, T.3
  • 26
    • 30644477046 scopus 로고    scopus 로고
    • A single member of the Plasmodium falciparum var multigene family determines cytoadhesion to the placental receptor chondroitin sulphate A
    • Viebig N.K., Gamain B., Scheidig C., et al. A single member of the Plasmodium falciparum var multigene family determines cytoadhesion to the placental receptor chondroitin sulphate A. EMBO Rep 6 (2005) 775-781
    • (2005) EMBO Rep , vol.6 , pp. 775-781
    • Viebig, N.K.1    Gamain, B.2    Scheidig, C.3
  • 27
    • 0042164921 scopus 로고    scopus 로고
    • Recovery of adhesion to chondroitin-4-sulphate in Plasmodium falciparum var CSA disruption mutants by antigenically similar PfEMP1 variants
    • Andrews K.T., Pirrit L.A., Przyborski J.M., et al. Recovery of adhesion to chondroitin-4-sulphate in Plasmodium falciparum var CSA disruption mutants by antigenically similar PfEMP1 variants. Mol Microbiol 49 (2003) 655-669
    • (2003) Mol Microbiol , vol.49 , pp. 655-669
    • Andrews, K.T.1    Pirrit, L.A.2    Przyborski, J.M.3
  • 28
    • 0008527390 scopus 로고    scopus 로고
    • Plasmodium falciparum domain mediating adhesion to chondroitin sulfate A: a receptor for human placental infection
    • Buffet P.A., Gamain B., Scheidig C., et al. Plasmodium falciparum domain mediating adhesion to chondroitin sulfate A: a receptor for human placental infection. Proc Natl Acad Sci USA 96 (1999) 12743-12748
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 12743-12748
    • Buffet, P.A.1    Gamain, B.2    Scheidig, C.3
  • 29
    • 0026552961 scopus 로고
    • Transcription mapping of a 100 kb locus of Plasmodium falciparum identifies an intergenic region in which transcription terminates and reinitiates
    • Lanzer M., de Bruin D., and Ravetch J.V. Transcription mapping of a 100 kb locus of Plasmodium falciparum identifies an intergenic region in which transcription terminates and reinitiates. EMBO J 11 (1992) 1949-1955
    • (1992) EMBO J , vol.11 , pp. 1949-1955
    • Lanzer, M.1    de Bruin, D.2    Ravetch, J.V.3
  • 30
    • 0023028750 scopus 로고
    • Histidine-rich domain of the knob protein of the human malaria parasite Plasmodium falciparum
    • Kilejian A., Sharma Y.D., Karoui H., and Naslund L. Histidine-rich domain of the knob protein of the human malaria parasite Plasmodium falciparum. Proc Natl Acad Sci USA 83 (1986) 7938-7941
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 7938-7941
    • Kilejian, A.1    Sharma, Y.D.2    Karoui, H.3    Naslund, L.4
  • 31
    • 0021109045 scopus 로고
    • Cloning and characterisation of the rRNA genes from the human malaria parasite Plasmodium falciparum
    • Langsley G., Hyde J.E., Goman M., and Scaife J.G. Cloning and characterisation of the rRNA genes from the human malaria parasite Plasmodium falciparum. Nucl Acids Res 11 (1983) 8703-8717
    • (1983) Nucl Acids Res , vol.11 , pp. 8703-8717
    • Langsley, G.1    Hyde, J.E.2    Goman, M.3    Scaife, J.G.4
  • 32
    • 0034704147 scopus 로고    scopus 로고
    • Characterization of proteoglycans of human placenta and identification of unique chondroitin sulfate proteoglycans of the intervillous spaces that mediate the adherence of Plasmodium falciparum-infected erythrocytes to the placenta
    • Achur R.N., Valiyaveettil M., Alkhalil A., Ockenhouse C.F., and Gowda D.C. Characterization of proteoglycans of human placenta and identification of unique chondroitin sulfate proteoglycans of the intervillous spaces that mediate the adherence of Plasmodium falciparum-infected erythrocytes to the placenta. J Biol Chem 275 (2000) 40344-40356
    • (2000) J Biol Chem , vol.275 , pp. 40344-40356
    • Achur, R.N.1    Valiyaveettil, M.2    Alkhalil, A.3    Ockenhouse, C.F.4    Gowda, D.C.5
  • 33
    • 0029970183 scopus 로고    scopus 로고
    • Primary culture of human lung microvessel endothelial cells: a useful in vitro model for studying Plasmodium falciparum-infected erythrocyte cytoadherence
    • Muanza K., Gay F., Behr C., and Scherf A. Primary culture of human lung microvessel endothelial cells: a useful in vitro model for studying Plasmodium falciparum-infected erythrocyte cytoadherence. Res Immunol 147 (1996) 149-163
    • (1996) Res Immunol , vol.147 , pp. 149-163
    • Muanza, K.1    Gay, F.2    Behr, C.3    Scherf, A.4
  • 34
    • 17044371098 scopus 로고    scopus 로고
    • Broad analysis reveals a consistent pattern of var gene transcription in Plasmodium falciparum repeatedly selected for a defined adhesion phenotype
    • Duffy M.F., Byrne T.J., Elliott S.R., et al. Broad analysis reveals a consistent pattern of var gene transcription in Plasmodium falciparum repeatedly selected for a defined adhesion phenotype. Mol Microbiol 56 (2005) 774-788
    • (2005) Mol Microbiol , vol.56 , pp. 774-788
    • Duffy, M.F.1    Byrne, T.J.2    Elliott, S.R.3
  • 35
    • 0037162472 scopus 로고    scopus 로고
    • Molecular basis for the dichotomy in Plasmodium falciparum adhesion to CD36 and chondroitin sulfate A
    • Gamain B., Gratepanche S., Miller L.H., and Baruch D.I. Molecular basis for the dichotomy in Plasmodium falciparum adhesion to CD36 and chondroitin sulfate A. Proc Natl Acad Sci USA 99 (2002) 10020-10024
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 10020-10024
    • Gamain, B.1    Gratepanche, S.2    Miller, L.H.3    Baruch, D.I.4
  • 36
    • 0037342720 scopus 로고    scopus 로고
    • Widespread functional specialization of Plasmodium falciparum erythrocyte membrane protein 1 family members to bind [CD36] analysed across a parasite genome
    • Robinson B.A., Welch T.L., and Smith J.D. Widespread functional specialization of Plasmodium falciparum erythrocyte membrane protein 1 family members to bind [CD36] analysed across a parasite genome. Mol Microbiol 47 (2003) 1265-1278
    • (2003) Mol Microbiol , vol.47 , pp. 1265-1278
    • Robinson, B.A.1    Welch, T.L.2    Smith, J.D.3
  • 37
    • 0026683042 scopus 로고
    • A sequence element associated with the Plasmodium falciparum KAHRP gene is the site of developmentally regulated protein-DNA interactions
    • Lanzer M., de Bruin D., and Ravetch J.V. A sequence element associated with the Plasmodium falciparum KAHRP gene is the site of developmentally regulated protein-DNA interactions. Nucl Acids Res 20 (1992) 3051-3056
    • (1992) Nucl Acids Res , vol.20 , pp. 3051-3056
    • Lanzer, M.1    de Bruin, D.2    Ravetch, J.V.3
  • 38
    • 18844462890 scopus 로고    scopus 로고
    • RNA polymerase I transcribes procyclin genes and variant surface glycoprotein gene expression sites in Trypanosoma brucei
    • Gunzl A., Bruderer T., Laufer G., et al. RNA polymerase I transcribes procyclin genes and variant surface glycoprotein gene expression sites in Trypanosoma brucei. Eukaryot Cell 2 (2003) 542-551
    • (2003) Eukaryot Cell , vol.2 , pp. 542-551
    • Gunzl, A.1    Bruderer, T.2    Laufer, G.3
  • 39
    • 0035856691 scopus 로고    scopus 로고
    • A pol I transcriptional body associated with VSG mono-allelic expression in Trypanosoma brucei
    • Navarro M., and Gull K. A pol I transcriptional body associated with VSG mono-allelic expression in Trypanosoma brucei. Nature 414 (2001) 759-763
    • (2001) Nature , vol.414 , pp. 759-763
    • Navarro, M.1    Gull, K.2
  • 40
    • 0016412414 scopus 로고
    • Eukaryotic nuclear RNA polymerases
    • Chambon P. Eukaryotic nuclear RNA polymerases. Annu Rev Biochem 44 (1975) 613-638
    • (1975) Annu Rev Biochem , vol.44 , pp. 613-638
    • Chambon, P.1
  • 41
    • 0025147221 scopus 로고
    • Coupled reverse transcription-polymerase chain reaction (RT-PCR) as a sensitive and rapid method for isozyme genotyping
    • Mocharla H., Mocharla R., and Hodes M.E. Coupled reverse transcription-polymerase chain reaction (RT-PCR) as a sensitive and rapid method for isozyme genotyping. Gene 93 (1990) 271-275
    • (1990) Gene , vol.93 , pp. 271-275
    • Mocharla, H.1    Mocharla, R.2    Hodes, M.E.3
  • 42
    • 0031791143 scopus 로고    scopus 로고
    • mRNA quantitation techniques: considerations for experimental design and application
    • Reue K. mRNA quantitation techniques: considerations for experimental design and application. J Nutr 128 (1998) 2038-2044
    • (1998) J Nutr , vol.128 , pp. 2038-2044
    • Reue, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.