Sensitive and specific LC-ESI-MS/MS method for the determination of a styrylquinoline, BA011FZ041, a potent HIV anti-integrase agent, in rat plasma

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 850, Issue 1-2, 2007, Pages 259-266

  Pruvost, Alain ^a   Levi, Mikaël ^b   Zouhiri, Fatima ^c   Ménier, Isabelle ^c   Benech, Henri ^a  

^a Institut National de la Recherche Agronomique   (France)

^b SPI BIO   (France)

^c BioAlliance Pharma   (France)

Author keywords

Anti integrase; HIV; LC MS MS; PBMCs; Plasma

Indexed keywords

ANTI INTEGRASE; RAT PLASMA; SOLID PHASE EXTRACTION (SPE);

BIOASSAY; BLOOD; DERIVATIVES; EXTRACTION; RATS; VIRUSES;

DRUG PRODUCTS;

BA 011FZ041; INTEGRASE INHIBITOR; STYRYLQUINOLINE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG ISOLATION; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SOLID PHASE EXTRACTION;

ANIMALS; CHROMATOGRAPHY, LIQUID; HIV INTEGRASE INHIBITORS; MALE; QUINOLINES; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

RATTUS;

EID: 34247478041     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2006.11.038     Document Type: Article

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