Improving tumor targeting and therapeutic potential of Salmonella VNP20009 by displaying cell surface CEA-specific antibodies

Vaccine

Volumn 25, Issue 21, 2007, Pages 4183-4192

  Bereta, Michal ^a   Hayhurst, Andrew ^b   Gajda, Mariusz ^a   Chorobik, Paulina ^c   Targosz, Marta ^c   Marcinkiewicz, Janusz ^a   Kaufman, Howard L ^d  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^b SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH   (United States)

^c JAGIELLONIAN UNIVERSITY   (Poland)

^d Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Cancer therapy; Carcinoembryonic antigen; Salmonella; scFv display; Vaccine vector

Indexed keywords

BACTERIUM VECTOR; CARCINOEMBRYONIC ANTIBODY SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY VACCINE; FLUORESCENT DYE; PLASMID VECTOR; TUMOR VACCINE; UNCLASSIFIED DRUG; VNP 20009;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ATOMIC FORCE MICROSCOPY; BACTERIAL STRAIN; CANCER; CANCER INHIBITION; CANCER THERAPY; CELL SURFACE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; IMMUNOGENICITY; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SALMONELLA TYPHIMURIUM; T LYMPHOCYTE; TRANSGENIC MOUSE; UPPER GASTROINTESTINAL TRACT;

ADENOCARCINOMA; ANIMALS; ANTIBODIES, NEOPLASM; ANTIGENS, CD11B; ANTIGENS, CD3; CARCINOEMBRYONIC ANTIGEN; DISEASE MODELS, ANIMAL; FEMALE; FLOW CYTOMETRY; GASTROINTESTINAL TRACT; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROSCOPY, ATOMIC FORCE; MICROSCOPY, CONFOCAL; SALMONELLA TYPHIMURIUM; T-LYMPHOCYTES; VACCINES, ATTENUATED;

EID: 34247477604     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2007.03.008     Document Type: Article

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