Identification of gene expression indicators for thyroid axis disruption in a Xenopus laevis metamorphosis screening assay. Part 1. Effects on the brain

Aquatic Toxicology

Volumn 82, Issue 4, 2007, Pages 227-241

  Helbing, Caren C ^a   Bailey, Carmen M ^a   Ji, Lan ^a   Gunderson, Mark P ^a   Zhang, Fang ^a   Veldhoen, Nik ^a   Skirrow, Rachel C ^a   Mu, Ruixia ^a   Lesperance, Mary ^a   Holcombe, Gary W ^b   Kosian, Patricia A ^b   Tietge, Joseph ^b   Korte, Joseph J ^b   Degitz, Sigmund J ^b  

^a UNIVERSITY OF VICTORIA   (Canada)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Amphibian; cDNA array; Frog; Metamorphosis; Quantitative real time polymerase chain reaction

Indexed keywords

COMPLEMENTARY DNA; ENDOCRINE DISRUPTOR; LIOTHYRONINE; MESSENGER RNA; MOLECULAR MARKER; PERCHLORATE; PROPYLTHIOURACIL; THIAMAZOLE; THYROID HORMONE; THYROXINE;

BIOASSAY; BIOINDICATOR; BRAIN; ENDOCRINE SYSTEM; FROG; GENE EXPRESSION; HORMONE; METAMORPHOSIS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; GENE EXPRESSION PROFILING; GENETIC IDENTIFICATION; INTERMETHOD COMPARISON; METAMORPHOSIS; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; POLLUTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SCREENING; TADPOLE; THYROID AXIS DISRUPTION; THYROID DISEASE; XENOPUS LAEVIS;

ANIMALS; BIOLOGICAL MARKERS; BRAIN; ENVIRONMENTAL MONITORING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; LARVA; METHIMAZOLE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PERCHLORIC ACID; PROPYLTHIOURACIL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THYROID HORMONES; TIME FACTORS; WATER POLLUTANTS, CHEMICAL; XENOPUS LAEVIS;

AMPHIBIA; ANURA; VERTEBRATA; XENOPUS LAEVIS;

EID: 34247402189     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aquatox.2007.02.013     Document Type: Article

References (51)

1. APHA. Standard methods for the examination of water and wastewater. (1992), DC American Public Health Association, American Water Works Association, Water Environment Foundation, Washington
2. Atkinson B.G., Helbing C., and Chen Y. Reprogramming of gene expression during amphibian metamorphosis. In: Gilbert L.I., Tata J., and Atkinson B.G. (Eds). Metamorphosis: postembryonic reprogramming of gene expression in amphibian and insect cells (1996), Academic Press, San Diego 539-566
3. Bassett J., Harvey C.B., and Williams G.R. Mechanisms of thyroid hormone receptor-specific nuclear and extra nuclear actions. Mol. Cell. Endocrinol. 213 (2003) 1-11
4. Becker K.B., Stephens K.C., Davey J.C., Schneider M.J., and Galton V.A. The type 2 and type 3 iodothyronine deiodinases play important roles in coordinating development in Rana catesbeiana tadpoles. Endocrinology 138 (1997) 2989-2997
5. Bekkedal M., Arfsten D., and Mattie D. An evaluation of neurobehavioral tests used to assess the neurodevelopmental effects of early ammonium perchlorate exposure. J. Tox. Environ. Health A 67 (2004) 835-844
6. Blasius J., and Greenacre M. Visualization of categorical data (1998), Academic Press, London
7. Buscaglia M., Leloup J., and deLuze A. In: Balls M., and Bownes M. (Eds). Metamorphosis (1985), Clarendon, New York 273-293
8. Busold C., Winter S., Hauser N., Bauer A., Dippon J., Hoheisel J., and Fellenberg K. Integration of GO annotations in correspondence analysis: facilitating the interpretation of microarray data. Bioinformatics 21 (2005) 2424-2429
9. Cooper D.S., Kieffer J.D., Saxe V., Mover H., Maloof F., and Ridgway E.C. Methimazole pharmacology in the rat: studies using a newly developed radioimmunoassay for methimazole. Endocrinology 114 (1984) 786-793
10. Crump D., Werry K., Veldhoen N., van Aggelen G., and Helbing C.C. Exposure to the herbicide acetochlor results in increased thyroid hormone-dependent gene expression and accelerated metamorphosis in Xenopus laevis. Enivron. Health Persp. 110 (2002) 1199-1205
11. Culhane A.G.P., Considine E., Cotter T., and Higgins D.G. Between-group analysis of microarray data. Bioinformatics 18 (2002) 1600-1608
12. Damjanovski S., Amano T., Li Q., Ueda S., Shi Y.-B., and Ishizuya-Oka A. Role of ECM remodeling in thyroid hormone-dependent apoptosis during anuran metamorphosis. Ann. New York Acad. Sci. 926 (2000) 180-191
13. Das B., Cai L., Carter M., Piao Y.-L., Sharov A., Ko M., and Brown D.D. Gene expression changes at metamorphosis induced by thyroid hormone in Xenopus laevis. Devel. Biol. 29 (2006) 342-355
14. Degitz S.J., Holcombe G.W., Flynn K.M., Kosian P.A., Korte J.J., and Tietge J.E. Progress towards development of an amphibian-based thyroid screening assay using Xenopus laevis. Organismal and thyroidal responses to model compounds 6-propylthiouracil, methimazole, and thyroxine. Tox. Sci. 87 (2005) 353-364
15. Denver R.J., Pavhi S., and Shi Y.B. Thyroid hormone-dependent gene expression program for Xenopus neural development. J. Biol. Chem. 272 (1997) 8179-8188
16. Eisen M.B., Spellman P.T., Brown P.O., and Botstein D. Cluster analysis and display of genome-wide expression patterns. Proc. Natl. Acad. Sci. U.S.A. 95 (1998) 14863-14868
17. EPA 1998. Endocrine Disruptor Screening and Testing Advisory Committee (EDSTAC): Final report. Environmental Protection Agency.
18. Fellenberg K., Hauser N., Brors B., Neutzner A., Hoheisel J., and Vingron M. Correspondence analysis applied to microarray data. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 10781-10786
19. Forrest D., Reh T., and Ruesch A. Neurodevelopmental control by thyroid hormone receptors. Curr. Opinion. Neurobiol. 12 (2002) 49-56
20. Greenacre M. Theory and applications of correspondence analysis (1984), Academic Press, London
21. Greenacre M. Correspondence analysis in practice (1993), Academic Press, London
22. Helbing C., Ji L., Veldhoen N., Zhang F., Holcombe G., Kosian P., Tietge J., and Degitz S. Identification of gene expression biomarkers that rapidly detect exposure to thyroid hormones, methimazole, propylthiouracil and perchlorate in a Xenopus laevis metamorphosis screening assay. Part 2. Effects on the tail and hindlimb. Aquat. Toxicol. 82 (2007) 215-226
23. Helbing C., Werry K., Crump D., Domanski D., Veldhoen N., and Bailey C. Expression profiles of novel thyroid hormone-responsive genes and proteins in the tail of Xenopus laevis tadpoles undergoing precocious metamorphosis. Mol. Endocrinol. 17 (2003) 1395-1409
24. Helbing C.C., Ovaska K., and Ji L. Evaluation of the effect of acetochlor on thyroid hormone receptor gene expression in the brain and behavior of Rana catesbeiana tadpoles. Aquat. Toxicol. 80 (2006) 42-51
25. Huang H., Marsh-Armstrong N., and Brown D. Metamorphosis is inhibited in transgenic Xenopus laevis tadpoles that over express type III deiodinase. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 962-967
26. Jones I., and Forrest D. The thyroid hormone receptor β gene: structure and functions in the brain and sensory systems. Thyroid 13 (2003) 1057-1068
27. Kawahara A., Gohda Y., and Hikosaka A. Role of type III iodothyronine 5-deiodinase gene expression in temporal regulation of Xenopus metamorphosis. Dev. Growth Differ. 41 (1999) 365-373
28. Krain L., and Denver R. Developmental expression and hormonal regulation of glucocorticoid and thyroid hormone receptors during metamorphosis in Xenopus laevis. J. Endocrinol. 181 (2004) 91-104
29. Montgomery, D. (Ed.), 1991. Introduction to Statistical Quality Control. Wiley, Hoboken, NJ, p. 204.
30. Nieuwkoop P.D., and Faber J. Normal table of Xenopus laevis (1956), North Holland Publishing, Amsterdam
31. Opitz R., Hartmann S., Blank T., Braunbeck T., Lutz I., and Kloas W. Evaluation of histological and molecular endpoints for enhanced detection of thyroid system disruption in Xenopus laevis tadpoles. Tox. Sci. 90 (2006) 337-348
32. Sachs L.M., Amano T., and Shi Y.B. An essential role of histone deacetylases in postembryonic organ transformations in Xenopus laevis. Int. J. Mol. Med. 8 (2001) 595-601
33. Sap J., Munoz A., Damm K., Goldberg Y., Bhysdael J., Leutz A., Beug H., and Vennstrom B. The c-erbA protein is a high affinity receptor for thyroid hormone. Nature 324 (1986) 635-640
34. Shi Y.-B. Amphibian Metamorphosis: from morphology to molecular biology (2000), Wiley-Liss, New York
35. Shi Y.-B., and Hayes W.P. Thyroid hormone-dependent regulation of the intenstinal fatty acid-binding protein gene during amphibian metamorphosis. Devel. Biol. 161 (1994) 48-58
36. Siesser W.B., Cheng S.-Y., and McDonald M. Hyperactivity, impaired learning on a vigilance task, and a differential response to methylphenidate in the TRβPV knock-in mouse. Psychopharmacology 181 (2005) 653-663
37. Soldin O.P., Braverman L.E., and Lamm S.H. Perchlorate clinical pharmacology and human health: a review. Ther. Drug Monitor. 23 (2001) 316-331
38. Tan Q., Brusgaard K., Kruse A., Oakeley E., Hemmings B., Beck-Nielsen H., Hansen L., and Gaster M. Correspondence analysis of microarray time-course data in case-control design. J. Biomed. Informatics 37 (2004) 358-365
39. Tietge J.E., Holcombe G.W., Flynn K.M., Kosian P.A., Korte J.J., Anderson L.E., Wolf D.C., and Degitz S.J. Metamorphic inhibition of Xenopus laevis by sodium perchlorate: effects on development and thyroid histology. Environ. Tox. Chem. 24 (2005) 926-933
40. Turque N., Palmier K., Le Mevel S., Alliot C., and Demeneix B. A rapid, physiologic protocol for testing transcriptional effects of thyroid-disrupting agents in permetamorphic Xenopus tadpoles. Enivron. Health Persp. 113 (2005) 1588-1593
41. Urbansky E.T. Perchlorate chemistry: implications for analysis and remediation. Bioremed. J. 2 (1998) 81-95
42. Veldhoen N., Boggs A., Walzak K., and Helbing C.C. Exposure to tetrabromobisphenol-A alters TH-associated gene expression and tadpole metamorphosis in the Pacific Tree Frog Pseudacris regilla. Aquat. Toxicol. 78 (2006) 292-302
43. Veldhoen N., Skirrow R., Ji L., Domanski D., Bonfield E., Bailey C., and Helbing C. Use of heterologous cDNA arrays and organ culture in the detection of thyroid hormone-dependent responses in a sentinel frog Rana catesbeiana. Comp. Biochem. Physiol. D 1 (2006) 187-199
44. Veldhoen N., Skirrow R., Osachoff H., Wigmore H., Clapson D., Gunderson M., van Aggelen G., and Helbing C. The bactericidal agent Triclosan modulates thyroid hormone-associated gene expression and disrupts postembryonic anuran development. Aquat. Toxicol. 80 (2006) 217-227
45. Wagner M., and Helbing C. Multiple variants of the ING1 and ING2 tumor suppressors are differentially expressed and thyroid hormone-responsive in Xenopus laevis. Gen. Comp. Endocrinol. 144 (2005) 38-50
46. Weinberger C., Thompson C., Ong E., Lebo R., Gruol D., and Evans R. The c-erbA gene encodes a thyroid hormone receptor. Nature 324 (1986) 641-646
47. Wolff J. Perchlorate and the thyroid gland. Pharm. Rev. 50 (1998) 89-105
48. Zhang F., Degitz S.J., Holcombe G.W., Kosian P.A., Tietge J., Veldhoen N., and Helbing C.C. Evaluation of gene expression endpoints in the context of a Xenopus laevis metamorphosis-based bioassay to detect thyroid hormone disruptors. Aquat. Toxicol. 76 (2006) 24-36
49. Zoeller R. Maternal thyroid hormone affects fetal brain development. Neurotoxicology 22 (2001) 131-132
50. Zoeller R. Environmental chemicals as thyroid hormone analogues: New studies indicate that thyroid hormone receptors are targets of industrial chemicals. Mol. Cell. Endocrinol. 242 (2005) 10-15
51. Zoeller R.T., and Crofton K.M. Thyroid hormone action in fetal brain development and potential for disruption by environmental chemicals. Neurotoxicology 23 (2000) 935-946