The solution structure of horseshoe crab antimicrobial peptide tachystatin B with an inhibitory cystine-knot motif

Journal of Peptide Science

Volumn 13, Issue 4, 2007, Pages 269-279

  Fujitani, Naoki ^a   Kouno, Takahide ^b   Nakahara, Taku ^a   Takaya, Kenji ^a   Osaki, Tsukasa ^c,e   Kawabata, Shun Ichiro ^c   Mizuguchi, Mineyuki ^b   Aizawa, Tomoyasu ^a   Demura, Makoto ^a   Nishimura, Shin Ichiro ^a,d   Kawano, Keiichi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b UNIVERSITY OF TOYAMA   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

^d NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^e NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Antimicrobial peptide; Inhibitory cystine knot (ICK) motif; Inmate immunity; NMR; Structure determination; Tachystatin B

Indexed keywords

ANTIBIOTIC AGENT; ARGININE; CHITIN; CYSTEINE; ION CHANNEL; POLYPEPTIDE ANTIBIOTIC AGENT; TACHYSTATIN A; TACHYSTATIN B; TACHYSTATIN B1; TACHYSTATIN B2; TYROSINE; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; BETA SHEET; CALCULATION; CONTROLLED STUDY; DRUG PROTEIN BINDING; GEOMETRY; INSECTICIDAL ACTIVITY; LIMULUS; MOLECULAR EVOLUTION; NEUROTOXICITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; BINDING SITES; CHITIN; CYSTEINE; HORSESHOE CRABS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; SOLUTIONS; STRUCTURAL HOMOLOGY, PROTEIN;

MEROSTOMATA; TACHYPLEUS TRIDENTATUS;

EID: 34247351569     PISSN: 10752617     EISSN: 10991387     Source Type: Journal    
DOI: 10.1002/psc.846     Document Type: Article

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