Microsatellite instability in long-standing ulcerative colitis

Scandinavian Journal of Gastroenterology

Volumn 42, Issue 5, 2007, Pages 586-591

  Løvig, Tone ^a,b   Andersen, Solveig Norheim ^a   Clausen, Ole Petter ^b   Rognum, Torleiv Ole ^a  

^a AKERSHUS UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

Dysplasia; Microsatellite instability; Ulcerative colitis

Indexed keywords

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COLON ADENOMA; COLON BIOPSY; COLON CARCINOGENESIS; COLON MUCOSA; DISEASE MARKER; FEMALE; GASTROINTESTINAL DYSPLASIA; GENE LOCUS; GENE MUTATION; HUMAN; HUMAN TISSUE; INTESTINE VILLUS; MALE; MICROSATELLITE INSTABILITY; PRIORITY JOURNAL; TISSUE FIXATION; TISSUE SECTION; ULCERATIVE COLITIS;

ADULT; AGED; ALLELES; CELL LINE, TUMOR; COLITIS, ULCERATIVE; COLORECTAL NEOPLASMS; DNA, NEOPLASM; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; FOLLOW-UP STUDIES; HUMANS; INTESTINAL MUCOSA; MALE; MICROSATELLITE INSTABILITY; MIDDLE AGED; POLYMERASE CHAIN REACTION; PRECANCEROUS CONDITIONS; PROCTOCOLECTOMY, RESTORATIVE; PROGNOSIS; TIME FACTORS; TUMOR MARKERS, BIOLOGICAL;

EID: 34247333785     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.1080/00365520601013747     Document Type: Article

References (33)

1. Ekbom A, Helmick C, Zack M, Adami HO. Ulcerative colitis and colorectal cancer. A population-based study. N Engl J Med 1990;323:1228-33.
2. Choi PM, Zelig MP. Similarity of colorectal cancer in Crohn's disease and ulcerative colitis: implications for carcinogenesis and prevention. Gut 1994;35:950-4.
3. Yin J, Harpaz N, Tong Y, Huang Y, Laurin J, Greenwald BD, et al. p53 point mutations in dysplastic and cancerous ulcerative colitis lesions. Gastroenterology 1993;104:1633-9.
4. Redston MS, Papadopoulos N, Caldas C, Kinzler KW, Kern SE. Common occurrence of APC and K-ras gene mutations in the spectrum of colitis-associated neoplasias. Gastroenterology 1995;108:383-92.
5. Jen J, Powell SM, Papadopoulos N, Smith KJ, Hamilton SR, Vogelstein B, et al. Molecular determinants of dysplasia in colorectal lesions. Cancer Res 1994;54:5523-6.
6. Burmer GC, Levine DS, Kulander BG, Haggitt RC, Rubin CE, Rabinovitch PS. c-Ki-ras mutations in chronic ulcerative colitis and sporadic colon carcinoma. Gastroenterology 1990;99:416-20.
7. Chaubert P, Benhattar J, Saraga E, Costa J. K-ras mutations and p53 alterations in neoplastic and nonneoplastic lesions associated with longstanding ulcerative colitis. Am J Pathol 1994;144:767-75.
8. Bell SM, Kelly SA, Hoyle JA, Lewis FA, Taylor GR, Thompson H, et al. c-Ki-ras gene mutations in dysplasia and carcinomas complicating ulcerative colitis. Br J Cancer 1991;64:174-8.
9. Meltzer SJ, Mane SM, Wood PK, Resau JH, Newkirk C, Terzakis JA, et al. Activation of c-Ki-ras in human gastrointestinal dysplasias determined by direct sequencing of polymerase chain reaction products. Cancer Res 1990;50:3627-30.
10. Andersen SN, Løvig T, Clausen OP, Bakka A, Fausa O, Rognum TO. Villous, hypermucinous mucosa in longstanding ulcerative colitis shows high frequency of K-ras mutations. Gut 1999;45:686-92.
11. Suzuki H, Harpaz N, Tarmin L, Yin J, Jiang HY, Bell JD, et al. Microsatellite instability in ulcerative colitis-associated colorectal dysplasias and cancers. Cancer Res 1994;54:4841-4.
12. Lyda MH, Noffsinger A, Belli J, Fenoglio-Preiser CM. Microsatellite instability and K-ras mutations in patients with ulcerative colitis. Hum Pathol 2000;31:665-71.
13. Heinen CD, Noffsinger AE, Belli J, Straughen J, Fischer J, Groden J, et al. Regenerative lesions in ulcerative colitis are characterized by microsatellite mutation. Genes Chromosomes Cancer 1997;19:170-5.
14. Ishitsuka T, Kashiwagi H, Konishi F. Microsatellite instability in inflamed and neoplastic epithelium in ulcerative colitis. J Clin Pathol 2001;54:526-32.
15. Brentnall TA, Crispin DA, Bronner MP, Cherian SP, Hueffed M, Rabinovitch PS, et al. Microsatellite instability in nonneoplastic mucosa from patients with chronic ulcerative colitis. Cancer Res 1996;56:1237-40.
16. Willenbucher RF, Aust DE, Chang CG, Zelman SJ, Ferrell LD, Moore DH, II, et al. Genomic instability is an early event during the progression pathway of ulcerative-colitisrelated neoplasia. Am J Pathol 1999;154:1825-30.
17. Matsumoto N, Yoshida T, Okayasu I. High epithelial and stromal genetic instability of chromosome 17 in ulcerative colitis-associated carcinogenesis. Cancer Res 2003;63:6158-61.
18. Fleisher AS, Esteller M, Harpaz N, Leytin A, Rashid A, Xu Y, et al. Microsatellite instability in inflammatory bowel disease-associated neoplastic lesions is associated with hypermethylation and diminished expression of the DNA mismatch repair gene, hMLH1. Cancer Res 2000;60:4864-8.
19. Takahashi S, Kojima Y, Kinouchi Y, Negoro K, Takagi S, Aihara H, et al. Microsatellite instability and loss of heterozygosity in the nondysplastic colonic epithelium of ulcerative colitis. J Gastroenterol 2003;38:734-9.
20. Hoff-Olsen P, Meling GI, Olaisen B. Somatic mutations in VNTR-locus D1S7 in human colorectal carcinomas are associated with microsatellite instability. Hum Mutation 1995;5:329-32.
21. Gillespie JW, Best CJ, Bichsel VE, Cole KA, Greenhut SF, Hewitt SM, et al. Evaluation of non-formalin tissue fixation for molecular profiling studies. Am J Pathol 2002;160:449-57.
22. Riddell RH. Dysplasia in inflammatory bowel disease: standardized classification with provisional clinical applications. Hum Pathol 1983;14:931-68.
23. Morson B, Jass J, Sobin L. Precancerous lesions of the gastrointestinal tract. A histological classification London: Balliere Tindal; 1985.
24. Boland CR, Thibodeau SN, Hamilton SR, Sidransky D, Eshleman JR, Burt RW, et al. A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998;58:5248-57.
25. Southern EM. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol 1975;98:503-17.
26. Dimo-Simonin N, Brandt-Casadevall C, Gujer HR. Chemiluminescent DNA probes: evaluation and usefulness in forensic cases. Forensic Sci Int 1992;57:119-27.
27. Lothe RA, Andersen SN, Hofstad B, Meling GI, Peltomäki P, Heim S, et al. Deletion of 1p loci and microsatellite instability in colorectal polyps. Genes Chromosomes Cancer 1995;14:182-8.
28. Hofseth LJ, Khan MA, Ambrose M, Nikolayeva O, Xu-Welliver M, Kartalou M, et al. The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation. J Clin Invest 2003;112:1887-94.
29. Hoang JM, Cottu PH, Thuille B, Salmon RJ, Thomas G, Hamelin R. BAT-26, an indicator of the replication error phenotype in colorectal cancers and cell lines. Cancer Res 1997;57:300-3.
30. Souza RF, Lei J, Yin J, Appel R, Zou TT, Zhou X, et al. A transforming growth factor beta 1 receptor type II mutation in ulcerative colitis-associated neoplasms. Gastroenterology 1997;112:40-5.
31. Noffsinger AE, Belli JM, Fogt F, Fischer J, Goldman H, Fenoglio-Preiser CM. A germline hMSH2 alteration is unrelated to colonic microsatellite instability in patients with ulcerative colitis. Hum Pathol 1999;30:8-12.
32. Loeb KR, Loeb LA. Genetic instability and the mutator phenotype. Studies in ulcerative colitis. Am J Pathol 1999;154:1621-6.
33. Chang CL, Marra G, Chauhan DP, Ha HT, Chang DK, Ricciardiello L, et al. Oxidative stress inactivates the human DNA mismatch repair system. Am J Physiol Cell Physiol 2002;283:C148-54.