Preservation of steatotic livers: A comparison between cold storage and machine perfusion preservation

Liver Transplantation

Volumn 13, Issue 4, 2007, Pages 497-504

  Bessems, Maud ^a   Doorschodt, Benedict M ^a   Kolkert, Joe L P ^a   Vetelainen, Reeta L ^a   van Vliet, Arlene K ^a   Vreeling, Heleen ^a   van Marle, Jan ^a   van Gulik, Thomas M ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMMONIA; CHOLINE; EOSIN; GLUCONIC ACID; HEMATOXYLIN; HYALURONIC ACID; LIVER ENZYME; METHIONINE; UNIVERSITY OF WISCONSIN SOLUTION; UREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE; CONTROLLED STUDY; CRYOPRESERVATION; DONOR; FATTY LIVER; HISTOLOGY; INDUCED HYPOTHERMIA; INTERMETHOD COMPARISON; LIVER BIOPSY; LIVER FUNCTION; LIVER FUNCTION TEST; LIVER INJURY; LIVER PERFUSION; MACHINE; MALE; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RAT; STAINING;

ANIMALS; COLD; FATTY LIVER; HUMANS; LIVER FUNCTION TESTS; LIVER TRANSPLANTATION; MALE; METHIONINE; MODELS, ANIMAL; ORGAN PRESERVATION; PERFUSION; RATS; RATS, WISTAR; REPERFUSION; TISSUE DONORS;

EID: 34247261587     PISSN: 15276465     EISSN: 15276473     Source Type: Journal    
DOI: 10.1002/lt.21039     Document Type: Article

References (51)

1. Angulo P. Nonalcoholic fatty liver disease and liver transplantation. Liver Transpl 2006; 12:523-534.
2. Gruttadauria S, Cintorino D, Mandala' L, Musumeci A, Volpes R, Vizzini GB, et al. Acceptance of marginal liver donors increases the volume of liver transplant: early results of a single-center experience. Transplant Proc 2005; 37:2567-2568.
3. Renz JF, Kim C, Kinkhabwala. M, Jan D, Varadarajan R, Goldstein M, et al. Utilization of extended donor criteria liver allografts, maximizes donor use and patient access to liver transplantation. Ann Surg 2005;242:556-563.
4. Fishbein M Fiel MI, Emre S, Cubukcu O, Guy SR, Schwartz ME, et al. Use of livers with microvesicular fat safely expands the donor pool. Transplantation 1997;64: 248-251.
5. Selzner M, Clavien PA. Fatty liver in liver transplantation and surgery. Semin Liver Dis 2001;21:105-113.
6. Rinella ME, Alonso E, Rao S, Whitington P, Fryer J, Abecassis M, et al. Body mass index as a predictor of hepatic steatosis in living liver donors. Liver Transpl 200 1; 7:409-414.
7. Busquets J, Figueras J, Serrano T, Torras J, Ramos E, Rafecas A, et al. Postreperfusion biopsies are useful in predicting complications after liver transplantation. Liver Transpl 2001;7:432-435.
8. Busquets J, Serrano T, Figueras J, Ramos E, Torras J, Rafecas A, et al. Influence of donor post-reperfusion changes on graft evolution after liver transplant. Rev Esp Enferm Dig 2001;93:39-47.
9. Verran D, Kusyk T, Painter D, Fisher J, Koorey D, Strasser S, et al. Clinical experience gained from the use of 120 steatotic donor livers for orthotopic liver transplantation. Liver Transpl 2003;9: 500-505.
10. Hayashi M, Tokunaga Y, Fujita T, Tanaka K, Yamaoka Y, Ozawa K. The effects of cold preservation on steatotic graft viability in rat liver transplantation. Transplantation 1993;56:282-287.
11. George J, Pera. N, Phung N, Leclercq I, Yun HJ, Farrell G. Lipid peroxidation, stellate cell activation and hepatic fibrogenesis. in a rat model of chronic steatobepatitis. J Hepatol 2003;39:756-764.
12. Teramoto K, Bowers JL, Kruskal JB, Clouse ME. Hepatic microcirculatory changes after reperfusion in fatty and normal liver transplantation in the rat. Transplantation 1993;56:1076-1082.
13. Nakano H, Nagasaki H, Barama A, Boudjema K, Jaeck D, Kumada K, et al. The effects of N-acetylcysteine and anti-intercellular adhesion molecule- 1 monoclonal antibody against ischemia-reperfusion injury of the rat steatotic liver produced by a choline-methionine-deficient diet. Hepatology 1997;26:670-678.
14. Caraceni P, Bianchi C, Domenicali M, Maria PA, Maiolini E, Parenti CG, et al. Impairment of mitochondrial oxidative phosphorylation in rat fatty liver exposed to preservation-reperfusion injury. J Hepatol 2004;41:82-88.
15. Rubinsky B. Principles of low temperature cell preservation. Heart Fail Rev 2003;8:277-284.
16. McLaren AJ, Friend PJ. Trends in organ preservation. Transpl Int 2003; 16:701-708.
17. St Peter SD, Imber CJ, Friend PJ. Liver and kidney preservation by perfusion. Lancet 2002;359:604-613.
18. Lee CY, Zhang JX, Jones JW, Jr, Southard JH, Clemens MG. Functional recovery of preserved livers following warm ischemia: improvement by machine perfusion preservation. Transplantation 2002;74:944-951.
19. Compagnon P, Clement B, Campion JP, Boudjema. K. Effects of hypothermic machine perfusion on rat liver function depending on the route of perfusion. Transplantation 2001;72:606-614.
20. Uchiyama M, Matsuno N, Nakamura Y, Iwamoto H, Hama K, Narumi K, et al. Usefulness of preservation by machine perfusion of liver grafts from non-heart-beating donors-a porcine model. Transplant Proc 2003;35:105-106.
21. Bessems M, Doorschodt BM, van Vliet AK, van Gulik TM. Improved rat liver preservation by hypothermic continuous machine perfusion using polysol, a new, enriched preservation solution. Liver Transpl 2005;11:539-546.
22. Boudjema K, Lindell SL, Belzer FO, Southard JH. Effects of method of preservation on functions of livers from fed and fasted rabbits. Cryobiology 1991;28:227-236.
23. Lee CY, Jain S, Duncan HM, Zhang JX, Jones JW, Jr., Southard JH, et al. Survival transplantation of preserved non-heart-beating donor rat livers: preservation by hypothermic machine perfusion. Transplantation 2003;76: 1432-1436.
24. Polyak MM, Arrington BO, Stubenbord VVT, Boykin J, Brown T, Jean-Jacques MA, et al. The influence of pulsatile preservation on renal transplantation in the 1990s. Transplantation 2000;69:249-258.
25. Lindell S, Nobel M, Rankin M, D'Alessandro A, Southard JH. Optimal pH for simple cold storage or machine perfusion of dog kidneys with UW solution. Transpl Int 1998; 11:208-211.
26. Starkel P, Sempoux C, Leclercq I, Herin M, Deby C, Desager JP, et al. Oxidative stress, KLF6 and transforming growth factor-beta up-regulation differentiate non-alcoholic steatohepatitis progressing to fibrosis from uncomplicated steatosis in rats. J Hepatol 2003;39:538-546.
27. Dobrin PB. Effect of histologic preparation on the cross-sectional area of arterial rings. J Surg Res 1996;61:413-415.
28. Folch J, Lees M, Sloane Stanley GH. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 1957;226:497-509.
29. Chichibu K, Matsuura T, Shichijo S, Yokoyama MM. Assay of serum hyaluronic acid in clinical application. Clin Chim Acta 1989;181:317-323.
30. Fonseca-Wollheim F. Direct determination of plasma ammonia without deproteinization. An improved enzymic determination of ammonia, II [author's translation of title]. Z Klin Chem Klin Biochem 1973;11:426-431.
31. Crocker CL. Rapid determination of urea nitrogen in serum or plasma without deproteinization. Am J Med Technol 1967;33:361-365.
32. Sprangcrs F, Sauerwein HP, Romijn JA, Van Woerkom GM, Meijer AJ. Nitric oxide inhibits glycogen synthesis in isolated rat hepatocytes. Biochem J 1998;330:1045-1049.
33. Tietze F. Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal Biochem 1969;27:502-522.
34. Tojimbara T, Wicomb WN, Garcia-Kennedy R, Burns W, Hayashi M, Collins G, et al. Liver transplantation from non-heart beating donors in rats: influence of viscosity and temperature of initial flushing solutions on graft function. Liver Transpl Surg 1997;3:39-45.
35. Martin H, Bournique B, Sarsat JP, Albaladejo V, Lerche-Langrand C. Cryopreserved rat liver slices: a critical evaluation of cell viability, histological integrity, and drug-metabolizing enzymes. Cryobiology 2000;41:135-144.
36. Cheng YF, Chen CL, Lai CY, Chen TY, Huang TL, Lee TY, et al. Assessment of donor fatty livers for liver transplantation. Transplantation 2001;71:1221-1225.
37. Teramoto K, Bowers JL, Khettry U, Palombo JD, Clouse ME. A rat fatty liver transplant model. Transplantation 1993;55:737-741.
38. Alpers DH, Sabesin SM. Fatty liver: biochemical and clinical aspects. In: Diseases of the Liver. Philadelphia: Lippincott, 1987:949.
39. Grattagliano I, Caraceni P, Portincasa P, Domenicali M, Palmieri VO, Trevisani F, et al. Adaptation of subcellular glutathione detoxification system to stress conditions in choline-deficient diet induced rat fatty liver. Cell Biol Toxicol 2003;19:355-366.
40. Koteish A, Diehl AM. Animal models of steatosis. Semin Liver Dis 2001;21:89-104.
41. Tolba RH, Putz U, Decker D, Dombrowski F, Lauschke H. L-carnitine ameliorates abnormal vulnerability of steatotic rat livers to cold ischemic preservation. Transplantation 2003;76:1681-1686.
42. Koneru B, Reddy MC, la Torre AN, Patel D, Ippolito T, Ferrante P.J. Studies of hepatic warm ischemia in the obese Zucker rat. Transplantation 1995;59:942-946.
43. Selzner M, Rudiger HA, Sindram D, Madden J, Clavien PA. Mechanisms of ischemic injury are different in the steatotic and normal rat liver. Hepatology 2000;32:1280-1288.
44. Bessems M, 't Hart NA, Tolba R, Doorschodt BM, Leuvenink HG, Ploeg RJ, et al. The isolated perfused rat liver: standardization of a time-honoured model. Lab Anim 2006;40:236-246.
45. Shibayama Y, Nakata K. Role of hepatic artery in haemodynamics in normal and cirrhotic livers in rats. J Gastroenterol Hepatol 1991;6:591-594.
46. Gioli-Pereira L, Coradin K, Nagaoka MR, Borges DR, Kouyoumdjian M. Enzyme release from injured, preserved, and ex vivo reperfused liver does not indicate malfunction. Transplantation 2002;74:1081-1083.
47. Jain S, Xu H, Duncan H, Jones JW, Jr., Zhang JX, Clemens MG, et al. Ex-vivo study of flow dynamics and endothelial cell structure during extended hypothermic machine perfusion preservation of livers. Cryobiology 2004; 48:322-332.
48. Xu H, Lee CY, Clemens MG, Zhang JX. Prolonged hypothermic machine peifusion preserves hepatocellular function but potentiates endothelial cell dysfunction in rat livers. Transplantation 2004;77:1676-1682.
49. Reinders ME, van Wagensveld BA, van Gulik TM, Frederiks WM, Chamuleau RA, Endert E, et al. Hyaluxonic acid uptake in the assessment of sinusoidal endothelial cell damage after cold storage and normothermic reperfusion of rat livers. Transpl Int 1996;9:446-453.
50. Ohara K. Study of microcirculatory changes in experimental dietary fatty liver. Hokkaido, Igaku Zasshi 1989:64: 177-185. [Japanese]
51. Itasaka H, Suehiro T, Wakiyama S, Yanaga K, Shimada M, Sugimachi K. Significance of hyaluronic acid for evaluation of hepatic endothelial cell damage after cold preservation/reperfusion. J Surg Res 1995;59:589-595.