Nutritional deficiency after gastric bypass: diagnosis, prevention and treatment

Diabetes and Metabolism

Volumn 33, Issue 1, 2007, Pages 13-24

  Poitou Bernert, C ^a   Ciangura, C ^a   Coupaye, M ^a   Czernichow, S ^a   Bouillot, J L ^a   Basdevant, A ^a  

^a ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

Author keywords

Bariatric surgery; Malabsorption; Nutritional deficiency; Pregnancy; Review; Roux en Y gastric bypass; Supplementation; Vitamins

Indexed keywords

ALPHA TOCOPHEROL; CALCIUM; CARBOHYDRATE; CYANOCOBALAMIN; FOLIC ACID; IRON; LIPID; MAGNESIUM; POTASSIUM; PROTEIN; RETINOL; SELENIUM; THIAMINE; VITAMIN D; VITAMIN K GROUP; ZINC; TRACE ELEMENT; VITAMIN;

ALPHA TOCOPHEROL DEFICIENCY; CALCIUM DEFICIENCY; COMORBIDITY; FOLIC ACID DEFICIENCY; FOLLOW UP; HUMAN; IRON DEFICIENCY; MAGNESIUM DEFICIENCY; MALABSORPTION; MEGALOBLASTIC ANEMIA; NUTRITIONAL DEFICIENCY; OBESITY; POTASSIUM DEFICIENCY; RETINOL DEFICIENCY; REVIEW; ROUX Y ANASTOMOSIS; SELENIUM DEFICIENCY; STOMACH BYPASS; THIAMINE DEFICIENCY; VITAMIN DEFICIENCY; VITAMIN K DEFICIENCY; ZINC DEFICIENCY; DIET; FEMALE; MALNUTRITION; METHODOLOGY; PREGNANCY; PREGNANCY COMPLICATION;

DIET; FEMALE; GASTRIC BYPASS; HUMANS; MALNUTRITION; MICRONUTRIENTS; OBESITY; PREGNANCY; PREGNANCY COMPLICATIONS; VITAMINS;

EID: 34247259910     PISSN: 12623636     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diabet.2006.11.004     Document Type: Review

References (99)

1. Martin A. Apports nutritionnels conseillés pour la population française. In: Tec et Doc (Ed). Book Apports nutritionnels conseillés pour la population française (2001)
2. CNAM. Chirurgie digestive de l'obésité. Résultats enquête nationale (2004)
3. Oberlin P., and Mouquet M.C. La chirurgie en France de 1997 à 2003. Direction de la recherche des études de l'évaluation et des statistiques 2005 (2005) 410
4. Anaes. Chirurgie de l'obésité morbide de l'adulte. Rapport d'expertise de l'Anaes (2001)
5. Laville M., Romon M., Chavrier G., Guy-Grand B., Krempf M., Chevallier J.M., et al. Recommendations regarding obesity surgery. Obes. Surg. 15 (2005) 1476-1480
6. Sjostrom L., Lindroos A.K., Peltonen M., et al. Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N. Engl. J. Med. 351 (2004) 2683-2693
7. Buchwald H., Avidor Y., Braunwald E., Jensen M.D., Pories W., Fahrbach K., et al. Bariatric surgery: a systematic review and meta-analysis. JAMA 292 (2004) 1724-1737
8. Ponsky T.A., Brody F., and Pucci E. Alterations in gastrointestinal physiology after Roux-en-Y gastric bypass. J. Am. Coll. Surg. 201 (2005) 125-131
9. Xanthakos S.A., and Inge T.H. Nutritional consequences of bariatric surgery. Curr. Opin. Clin. Nutr. Metab. Care 9 (2006) 489-496
10. Service G.J., Thompson G.B., Service F.J., Andrews J.C., Collazo-Clavell M.L., and Lloyd R.V. Hyperinsulinemic hypoglycemia with nesidioblastosis after gastric-bypass surgery. N. Engl. J. Med. 353 (2005) 249-254
11. Service G.J., Thompson G.B., Service F.J., Andrews J.C., Collazo-Clavell M.L., and Lloyd R.V. Severe hypoglycaemia post-gastric bypass requiring partial pancreatectomy: evidence for inappropriate insulin secretion and pancreatic islet hyperplasia. Diabetologia 48 (2005) 2236-2240
12. Bloomberg R.D., Fleishman A., Nalle J.E., Herron D.M., and Kini S. Nutritional deficiencies following bariatric surgery: what have we learned?. Obes. Surg. 15 (2005) 145-154
13. Alvarez-Leite J.I. Nutrient deficiencies secondary to bariatric surgery. Curr. Opin. Clin. Nutr. Metab. Care 7 (2004) 569-575
14. Fujioka K. Follow-up of nutritional and metabolic problems after bariatric surgery. Diabetes Care 28 (2005) 481-484
15. Malinowski S.S. Nutritional and metabolic complications of bariatric surgery. Am. J. Med. Sci. 331 (2006) 219-225
16. Tomé D. Protéines alimentaires. In: Basdevant A., Laville M., and Lerebours E. (Eds). Traité de nutrition clinique de l'adulte (2001) 121-130 (Paris)
17. Sundbom M., Mardh E., Mardh S., Ohrvall M., and Gustavsson S. Reduction in serum pepsinogen I after Roux-en-Y gastric bypass. J. Gastrointest. Surg. 7 (2003) 529-535
18. Marceau S., Biron S., Lagace M., Hould F.S., Potvin M., Bourque R.A., et al. Biliopancreatic diversion, with distal gastrectomy, 250 cm and 50 cm limbs: long-term results. Obes. Surg. 5 (1995) 302-307
19. Kushner R. Managing the obese patient after bariatric surgery: a case report of severe malnutrition and review of the literature. JPEN J. Parenter. Enteral Nutr. 24 (2000) 126-132
20. Marinari G.M., Murelli F., Camerini G., Papadia F., Carlini F., Stabilini C., et al. A 15-year evaluation of biliopancreatic diversion according to the Bariatric Analysis Reporting Outcome System (BAROS). Obes. Surg. 14 (2004) 325-328
21. Rinaldi Schinkel E., Pettine S.M., Adams E., and Harris M. Impact of varying levels of protein intake on protein status indicators after gastric bypass in patients with multiple complications requiring nutritional support. Obes. Surg. 16 (2006) 24-30
22. Brolin R.E., LaMarca L.B., Kenler H.A., and Cody R.P. Malabsorptive gastric bypass in patients with superobesity. J. Gastrointest. Surg. 6 (2002) 195-203 (discussion 04-5)
23. Brolin R.E., Kenler H.A., Gorman J.H., and Cody R.P. Long-limb gastric bypass in the superobese. A prospective randomized study. Ann. Surg. 215 (1992) 387-395
24. Kalfarentzos F., Dimakopoulos A., Kehagias I., Loukidi A., and Mead N. Vertical banded gastroplasty versus standard or distal Roux-en-Y gastric bypass based on specific selection criteria in the morbidly obese: preliminary results. Obes. Surg. 9 (1999) 433-442
25. Faintuch J., Matsuda M., Cruz M.E., Silva M.M., Teivelis M.P., Garrido Jr. A.B., et al. Severe protein-calorie malnutrition after bariatric procedures. Obes. Surg. 14 (2004) 175-181
26. Skroubis G., Sakellaropoulos G., Pouggouras K., Mead N., Nikiforidis G., and Kalfarentzos F. Comparison of nutritional deficiencies after Roux-en-Y gastric bypass and after biliopancreatic diversion with Roux-en-Y gastric bypass. Obes. Surg. 12 (2002) 551-558
27. Lerebours E., Savoye G., and Ducrotte T. Physiologie du tube digestif. Physiologie du tube digestif (2001) 35-44
28. Walther B., Clementsson C., Vallgren S., Ihse I., and Akesson B. Fat malabsorption in patients before and after total gastrectomy, studied by the triolein breath test. Scand. J. Gastroenterol. 24 (1989) 309-314
29. Stael von Holstein C., Walther B., Ibrahimbegovic E., and Akesson B. Nutritional status after total and partial gastrectomy with Roux-en-Y reconstruction. Br. J. Surg. 78 (1991) 1084-1087
30. Behrns K.E., Smith C.D., and Sarr M.G. Prospective evaluation of gastric acid secretion and cobalamin absorption following gastric bypass for clinically severe obesity. Dig. Dis. Sci. 39 (1994) 315-320
31. Brolin R.E., Gorman J.H., Gorman R.C., Petschenik A.J., Bradley L.J., Kenler H.A., et al. Are vitamin B12 and folate deficiency clinically important after roux-en-Y gastric bypass?. J. Gastrointest. Surg. 2 (1998) 436-442
32. Rhode B.M., Tamin H., Gilfix B.M., Sampalis J.S., Nohr C., and MacLean L.D. Treatment of vitamin B12 deficiency after gastric surgery for severe obesity. Obes. Surg. 5 (1995) 154-158
33. Rhode B.M., Arseneau P., Cooper B.A., Katz M., Gilfix B.M., and MacLean L.D. Vitamin B-12 deficiency after gastric surgery for obesity. Am. J. Clin. Nutr. 63 (1996) 103-109
34. Yale C.E., Gohdes P.N., and Schilling R.F. Cobalamin absorption and hematologic status after two types of gastric surgery for obesity. Am. J. Hematol. 42 (1993) 63-66
35. Schilling R.F., Gohdes P.N., and Hardie G.H. Vitamin B12 deficiency after gastric bypass surgery for obesity. Ann. Intern. Med. 101 (1984) 501-502
36. Crowley L.V., Seay J., and Mullin G. Late effects of gastric bypass for obesity. Am. J. Gastroenterol. 79 (1984) 850-860
37. Koffman B.M., Greenfield L.J., Ali I.I., and Pirzada N.A. Neurologic complications after surgery for obesity. Muscle Nerve 33 (2006) 166-176
38. Halverson J.D. Metabolic risk of obesity surgery and long-term follow-up. Am. J. Clin. Nutr. 55 Suppl 2 (1992) 602S-605S
39. Amaral J.F., Thompson W.R., Caldwell M.D., Martin H.F., and Randall H.T. Prospective hematologic evaluation of gastric exclusion surgery for morbid obesity. Ann. Surg. 201 (1985) 186-193
40. Baghdasarian K.L. Gastric bypass and megaloblastic anemia. J. Am. Diet. Assoc. 80 (1982) 368-371
41. Crowley L.V., and Olson R.W. Megaloblastic anemia after gastric bypass for obesity. Am. J. Gastroenterol. 78 (1983) 406-410
42. Drummond J.F., White D.K., and Damm D.D. Megaloblastic anemia with oral lesions: a consequence of gastric bypass surgery. Oral Surg. Oral Med. Oral Pathol. 59 (1985) 149-153
43. MacLean L.D., Rhode B.M., and Shizgal H.M. Nutrition following gastric operations for morbid obesity. Ann. Surg. 198 (1983) 347-355
44. Halverson J.D. Micronutrient deficiencies after gastric bypass for morbid obesity. Am. Surg. 52 (1986) 594-598
45. Chaves L.C., Faintuch J., Kahwage S., and Alencar Fde A. A cluster of polyneuropathy and Wernicke-Korsakoff syndrome in a bariatric unit. Obes. Surg. 12 (2002) 328-334
46. Singh S., and Nautiyal A. Neurologic complications of bariatric surgery. Mayo Clin. Proc. 80 (2005) 136-137 (author reply 37)
47. Nautiyal A., Singh S., and Alaimo D.J. Wernicke encephalopathy-an emerging trend after bariatric surgery. Am. J. Med. 117 (2004) 804-805
48. Loh Y., Watson W.D., Verma A., Chang S.T., Stocker D.J., and Labutta R.J. Acute Wernicke's encephalopathy following bariatric surgery: clinical course and MRI correlation. Obes. Surg. 14 (2004) 129-132
49. Escalona A., Perez G., Leon F., Volaric C., Mellado P., Ibanez L., et al. Wernicke's encephalopathy after Roux-en-Y gastric bypass. Obes. Surg. 14 (2004) 1135-1137
50. Chang C.G., Adams-Huet B., and Provost D.A. Acute post-gastric reduction surgery (APGARS) neuropathy. Obes. Surg. 14 (2004) 182-189
51. Boylan L.M., Sugerman H.J., and Driskell J.A. Vitamin E, vitamin B-6, vitamin B-12, and folate status of gastric bypass surgery patients. J. Am. Diet. Assoc. 88 (1988) 579-585
52. Angstadt J.D., and Bodziner R.A. Peripheral polyneuropathy from thiamine deficiency following laparoscopic Roux-en-Y gastric bypass. Obes. Surg. 15 (2005) 890-892
53. Nanji A.A., and Freeman J.B. Gastric by-pass surgery in morbidly obese patients markedly decreases serum levels of vitamins A and C and iron in the perioperative period. Int. J. Obes. 9 (1985) 177-179
54. Lee W.B., Hamilton S.M., Harris J.P., and Schwab I.R. Ocular complications of hypovitaminosis A after bariatric surgery. Ophthalmology 112 (2005) 1031-1034
55. Hatizifotis M., Dolan K., Newbury L., and Fielding G. Symptomatic vitamin A deficiency following biliopancreatic diversion. Obes. Surg. 13 (2003) 655-657
56. Anastasi M., Lauricella M., and Ponte F. Surgical therapy for obesity can induce a vitamin A deficiency syndrome. Doc. Ophthalmol. 90 (1995) 143-155
57. Madan A.K., Orth W.S., Tichansky D.S., and Ternovits C.A. Vitamin and trace mineral levels after laparoscopic gastric bypass. Obes. Surg. 16 (2006) 603-606
58. Slater G.H., Ren C.J., Siegel N., Williams T., Barr D., Wolfe B., et al. Serum fat-soluble vitamin deficiency and abnormal calcium metabolism after malabsorptive bariatric surgery. J. Gastrointest. Surg. 8 (2004) 48-55 (discussion 54-5)
59. Goode L.R., Brolin R.E., Chowdhury H.A., and Shapses S.A. Bone and gastric bypass surgery: effects of dietary calcium and vitamin D. Obes. Res. 12 (2004) 40-47
60. Newbury L., Dolan K., Hatzifotis M., Low N., and Fielding G. Calcium and vitamin D depletion and elevated parathyroid hormone following biliopancreatic diversion. Obes. Surg. 13 (2003) 893-895
61. Shaker J.L., Norton A.J., Woods M.F., Fallon M.D., and Findling J.W. Secondary hyperparathyroidism and osteopenia in women following gastric exclusion surgery for obesity. Osteoporos. Int. 1 (1991) 177-181
62. Sanchez-Hernandez J., Ybarra J., Gich I., De Leiva A., Rius X., Rodriguez-Espinosa J., et al. Effects of bariatric surgery on vitamin D status and secondary hyperparathyroidism: a prospective study. Obes. Surg. 15 (2005) 1389-1395
63. Johnson J.M., Maher J.W., Samuel I., Heitshusen D., Doherty C., and Downs R.W. Effects of gastric bypass procedures on bone mineral density, calcium, parathyroid hormone, and vitamin D. J. Gastrointest. Surg. 9 (2005) 1106-1110 (discussion 10-1)
64. Diniz M.d.F., Diniz M.T., Sanches S.R., Salgado P.P., Valadao M.M., Araujo F.C., et al. Elevated serum parathormone after Roux-en-Y gastric bypass. Obes. Surg. 14 (2004) 1222-1226
65. Coates P.S., Fernstrom J.D., Fernstrom M.H., Schauer P.R., and Greenspan S.L. Gastric bypass surgery for morbid obesity leads to an increase in bone turnover and a decrease in bone mass. J. Clin. Endocrinol. Metab. 89 (2004) 1061-1065
66. Goldner W.S., O'Dorisio T.M., Dillon J.S., and Mason E.E. Severe metabolic bone disease as a long-term complication of obesity surgery. Obes. Surg. 12 (2002) 685-692
67. Von Mach M.A., Stoeckli R., Bilz S., Kraenzlin M., Langer I., and Keller U. Changes in bone mineral content after surgical treatment of morbid obesity. Metabolism 53 (2004) 918-921
68. Collazo-Clavell M.L., Jimenez A., Hodgson S.F., and Sarr M.G. Osteomalacia after Roux-en-Y gastric bypass. Endocr. Pract. 10 (2004) 195-198
69. Brolin R.E., Gorman J.H., Gorman R.C., Petschenik A.J., Bradley L.B., Kenler H.A., et al. Prophylactic iron supplementation after Roux-en-Y gastric bypass: a prospective, double-blind, randomized study. Arch. Surg. 133 (1998) 740-744
70. Brolin R.E., and Leung M. Survey of vitamin and mineral supplementation after gastric bypass and biliopancreatic diversion for morbid obesity. Obes. Surg. 9 (1999) 150-154
71. Avinoah E., Ovnat A., and Charuzi I. Nutritional status seven years after Roux-en-Y gastric bypass surgery. Surgery 111 (1992) 137-142
72. Rhode B.M., Shustik C., Christou N.V., and MacLean L.D. Iron absorption and therapy after gastric bypass. Obes. Surg. 9 (1999) 17-21
73. Trostler N., Mann A., Zilberbush N., Charuzi I.I., and Avinoach E. Nutrient intake following vertical banded gastroplasty or gastric bypass. Obes. Surg. 5 (1995) 403-410
74. Burge J.C., Schaumburg J.Z., Choban P.S., DiSilvestro R.A., and Flancbaum L. Changes in patients' taste acuity after Roux-en-Y gastric bypass for clinically severe obesity. J. Am. Diet. Assoc. 95 (1995) 666-670
75. Cominetti C., Garrido Jr. A.B., and Cozzolino S.M. Zinc nutritional status of morbidly obese patients before and after Roux-en-Y gastric bypass: a preliminary report. Obes. Surg. 16 (2006) 448-453
76. Neve H.J., Bhatti W.A., Soulsby C., Kincey J., and Taylor T.V. Reversal of hair loss following vertical gastroplasty when treated with zinc sulphate. Obes. Surg. 6 (1996) 63-65
77. Dolan K., Hatzifotis M., Newbury L., Lowe N., and Fielding G. A clinical and nutritional comparison of biliopancreatic diversion with and without duodenal switch. Ann. Surg. 240 (2004) 51-56
78. Kellum J.M., DeMaria E.J., and Sugerman H.J. The surgical treatment of morbid obesity. Curr. Probl. Surg. 35 (1998) 791-858
79. Elliot K. Nutritional considerations after bariatric surgery. Crit. Care Nurs. Q. 26 (2003) 133-138
80. Brolin R.E., Gorman R.C., Milgrim L.M., and Kenler H.A. Multivitamin prophylaxis in prevention of post-gastric bypass vitamin and mineral deficiencies. Int. J. Obes. 15 (1991) 661-667
81. Mallory G.N., and Macgregor A.M. Folate status following gastric bypass surgery (the great folate mystery). Obes. Surg. 1 (1991) 69-72
82. Provenzale D., Reinhold R.B., Golner B., Irwin V., Dallal G.E., Papathanasopoulos N., et al. Evidence for diminished B12 absorption after gastric bypass: oral supplementation does not prevent low plasma B12 levels in bypass patients. J. Am. Coll. Nutr. 11 (1992) 29-35
83. Smith C.D., Herkes S.B., Behrns K.E., Fairbanks V.F., Kelly K.A., and Sarr M.G. Gastric acid secretion and vitamin B12 absorption after vertical Roux-en-Y gastric bypass for morbid obesity. Ann. Surg. 218 (1993) 91-96
84. Brolin R.E. Metabolic deficiencies and supplements following bariatric operations. In: Mc Graw-Hill (Ed). Book Metabolic deficiencies and supplements following bariatric operations (2004) 275-300
85. Sifakis S., and Pharmakides G. Anemia in pregnancy. Ann. N. Y. Acad. Sci. 900 (2000) 125-136
86. Scholl T.O. Iron status during pregnancy: setting the stage for mother and infant. Am. J. Clin. Nutr. 81 (2005) 1218S-1222S
87. Weiler H., Fitzpatrick-Wong S., Veitch R., Kovacs H., Schellenberg J., McCloy U., et al. Vitamin D deficiency and whole-body and femur bone mass relative to weight in healthy newborns. CMAJ 172 (2005) 757-761
88. Javaid M.K., Crozier S.R., Harvey N.C., et al. Maternal vitamin D status during pregnancy and childhood bone mass at age 9 years: a longitudinal study. Lancet 367 (2006) 36-43
89. Specker B. Vitamin D requirements during pregnancy. Am. J. Clin. Nutr. 80 Suppl 6 (2004) 1740S-1747S
90. Vermiglio F., Lo Presti V.P., Moleti M., Sidoti M., Tortorella G., Scaffidi G., et al. Attention deficit and hyperactivity disorders in the offspring of mothers exposed to mild-moderate iodine deficiency: a possible novel iodine deficiency disorder in developed countries. J. Clin. Endocrinol. Metab. 89 (2004) 6054-6060
91. Kirke P.N., Daly L.E., Molloy A., Weir D.G., and Scott J.M. Maternal folate status and risk of neural tube defects. Lancet 348 (1996) 67-68
92. Grange D.K., and Finlay J.L. Nutritional vitamin B12 deficiency in a breastfed infant following maternal gastric bypass. Pediatr. Hematol. Oncol. 11 (1994) 311-318
93. Gurewitsch E.D., Smith-Levitin M., and Mack J. Pregnancy following gastric bypass surgery for morbid obesity. Obstet. Gynecol. 88 (1996) 658-661
94. Gray D.S., and Cabaniss M.L. Home total parenteral nutrition in a pregnant diabetic after jejunoileal bypass for obesity. JPEN J. Parenter. Enteral Nutr. 13 (1989) 214-217
95. Karamatsu J.T., Boyd A.T., Cooke J., Vinall P.S., and McMahon M.J. Intravenous nutrition during a twin pregnancy. JPEN J. Parenter. Enteral Nutr. 11 (1987) 499-501
96. Haddow J.E., Hill L.E., Kloza E.M., and Thanhauser D. Neural tube defects after gastric bypass. Lancet 1 (1986) 1330
97. Knudsen L.B., and Kallen B. Gastric bypass, pregnancy, and neural tube defects. Lancet 2 (1986) 227
98. Martin L., Chavez G.F., Adams Jr. M.J., et al. Gastric bypass surgery as maternal risk factor for neural tube defects. Lancet 1 (1988) 640-641
99. Ladipo O.A. Nutrition in pregnancy: mineral and vitamin supplements. Am. J. Clin. Nutr. 72 Suppl 1 (2000) 280S-290S