Combined cupric- and cuprous-binding peptides are effective in preventing IL-8 release from endothelial cells and redox reactions

Biochemical and Biophysical Research Communications

Volumn 357, Issue 2, 2007, Pages 543-548

  Rael, Leonard T ^a,b   Rao, Nagaraja K R ^c   Thomas, Gregory W ^a,b   Bar Or, Raphael ^a,b   Curtis, C Gerald ^d   Bar Or, David ^a,b  

^a SWEDISH MEDICAL CENTER   (United States)

^b DMI BioSciences Inc   (United States)

^c N N Scientific Ltd   (United Kingdom)

^d Bowman Research   (United States)

Author keywords

Copper; Hydroxyl radical; Inflammation; Ischemia reperfusion injury; Reactive oxygen species

Indexed keywords

AMINO ACID; ASCORBIC ACID; COPPER; INTERLEUKIN 8; PHORBOL 13 ACETATE 12 MYRISTATE; REACTIVE OXYGEN METABOLITE;

ARTICLE; CHELATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; METAL BINDING; OXIDATION REDUCTION POTENTIAL; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN MOTIF; UMBILICAL VEIN;

CELLS, CULTURED; COPPER; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; HUMANS; INTERLEUKIN-8; OXIDATION-REDUCTION; PEPTIDES; REACTIVE OXYGEN SPECIES; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 34247255838     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.03.182     Document Type: Article

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