Antiinflammatory properties of IL-10 rescue small-for-size liver grafts

Liver Transplantation

Volumn 13, Issue 4, 2007, Pages 558-565

  Yang, Zhen Fan ^a,b   Ho, David Wing Yuen ^a   Ngai, Patricia ^a   Lau, Chi Keung ^a   Zhao, Yi ^a   Poon, Ronnie Tung Ping ^a   Fan, Sheung Tat ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOGRAFT INFLAMMATORY FACTOR 1; CASPASE 9; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GRAFT FAILURE; GRAFT NECROSIS; GRAFT SURVIVAL; HISTOPATHOLOGY; LEWIS RAT; LIVER ISCHEMIA; LIVER SIZE; LIVER TRANSPLANTATION; MACROPHAGE; MALE; NONHUMAN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION; SURVIVAL RATE; UPREGULATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; INTERLEUKIN-10; LIVER; LIVER TRANSPLANTATION; MACROPHAGES; MALE; MODELS, ANIMAL; RATS; RATS, INBRED LEW; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSPLANTATION, ISOGENEIC;

EID: 34247235684     PISSN: 15276465     EISSN: 15276473     Source Type: Journal    
DOI: 10.1002/lt.21094     Document Type: Article

References (31)

1. Kiuchi T, Kasahara M, Uryuhara K, Inomata Y, Uemoto S, Asonuma. K, et al. Impact of graft size mismatching on graft prognosis in liver transplantation from living donors. Transplantation 1999;67:321-327.
2. Yang ZF, Ho DW, Chu AC, Wang YQ, Fan Sr. Linking inflammation to acute rejection in small-for-size liver allografts: the potential role of early macrophage activation. Am J Transplant 2004;4:196-209.
3. Man K, Fan ST, Lo CM, Liu CL, Fung PC, Liang TB, et al. Graft injury in relation to graft size in right lobe live donor liver transplantation: a study of hepatic sinusoidal injury in correlation with portal hemodynamics and intragraft gene expression. Ann Surg 2003;237:256-264.
4. Lo CM, Liu CL, Fan ST. Portal hyperperfusion injury as the cause of primary nonfunction in a small-for-size liver graft-successful treatment with splenic artery ligation. Liver Transpl 2003:9:626-628.
5. Yang ZF, Poon RT, Luo Y, Cheung CK, Ho DW, Lo CM, Fan ST. Upregulation of vascular endothelial growth factor (VEGF) in small-for-size liver grafts enhances macrophage activities through VEGF receptor 2-dependent pathway. J Immunol 2004;173:2507-2515.
6. Tian Y, Jochum W, Georgiev P, Moritz W, Graf R, Clavien PA. Kupffer cell-dependent TNF-alpha signaling mediates injury in the arterialized small-for-size liver transplantation in the mouse. Proc Natl Acad Sci USA 2006;103:4598-4603.
7. Utans U, Arceci RJ, Yamashita Y, Russell ME. Cloning and characterization of allograft inflammatory factor-1: a novel macrophage factor identified in rat cardiac allografts with chronic rejection. J Clin Invest 1995;95:2954-2962.
8. Autieri MV, Kelemen S, Thomas BA, Feller ED, Goldman BI, Eisen HJ. Allograft inflammatory factor-1 expression correlates with cardiac rejection and development of cardiac allograft vasculopathy. Circulation 2002;106:2218-2223.
9. Nagakawa Y, Nomoto S, Kato Y, Montgomery RA, Williams GM, Klein AS, Sun Z. Over-expression of AIF-1 in liver allografts and peripheral blood correlates with acute rejection after transplantation in rats. Am J Transplant 2004; 4:1949-1957.
10. Kelemen SE, Autieri MV. Expression of allograft inflammatory factor-1 in T lymphocytes: a role in T-lymphocyte activation and proliferative arteriopathies. Am J Pathol 2005;167:619-626.
11. Autieri MV, Kelemen SE, Wendt KW. AIF-1 is an actin-polymerizing and Rac1-activating protein that promotes vascular smooth muscle cell migration. Circ Res 2003;92: 1107-1114.
12. Watano K, Iwabuchi K, Fujii S, Ishimori N, Mitsuhashi S, Ato M, et al. Allograft inflammatory factor-1 augments production of interleukin-6, -10 and -12 by a mouse macrophage line. Immunology 2001:104:307-316.
13. Yang ZF, Ho DW, Lau CK, Lam CT, Lum CT, Poon RT, Fan ST. Allograft inflammatory factor-1 (AIF-1) is crucial for the survival and pro-inflammatory activity of macrophages. Int Immunol 2005;17:1391-1397.
14. Hawrylowicz CM, O'Garra A. Potential role of interleukin-1 10-secreting regulatory T cells in allergy and asthma. Nat Rev Immunol 2005;5:271-283.
15. Walsh PT, Taylor DK, Turka LA. Tregs and transplantation tolerance. J Clin Invest 2004;114:1398-1403.
16. Caruso C, Lio D, Cavallone L, Franceschi C. Aging, Iongevity, inflammation, and cancer. Ann NY Acad Sci 2004; 1028:1-13.
17. Zhao J, Pettigrew GJ, Bolton EM, Murfitt CR, Carmichael A, Bradley JA, Lever AM. Lentivirus-mediated gene transfer of viral interleukin-10 delays but does not prevent cardiac allograft rejection. Gene Ther 2005;12:1509-1516.
18. Salgar SK, Yang D, Ruiz P, Miller J, Tzakis AG. Viral interleukin-10-engineered autologous hematopoietic stem cell therapy: a novel gene therapy approach to prevent graft rejection. Hum Gene Ther 2004;15:131-144.
19. Itano H, Mora BN, Zhang W, Ritter JH, McCarthy TJ, Yew NS, et al. Lipid-mediated ex vivo gene transfer of viral interleukin 10 in rat lung allotransplantation. J Thorac Cardiovasc Surg 2001;122:29-38.
20. Yoshidome H, Kato A, Edwards MJ, Lentsch AB. Interleukin-10 suppresses hepatic ischemia/reperfusion injury in mice: implications of a central role for nuclear factor kappaB. Hepatology 1999:30:203-208.
21. Autieri MV, Carbone CM. Overexpression of allograft inflammatory factor-1 promotes proliferation of vascular smooth muscle cells by cell cycle deregulation. Arterioscler Thromb Vasc Biol 2001;21:1421-1426.
22. Koken T, Serteser M, Kahraman A, Akbulut G, Dilek ON. Which is more effective in the prevention of renal ischemia-reperfusion-induced oxidative injury in the early period in mice: interleukin (IL)-10 or anti-IL-12? Clin Biochem 2004:37:50-55.
23. Toth A, Halmosi R, Kovacs K, Deres P, Kalai T, Hideg K, et al. Akt activation induced by an antioxidant compound during ischemia-reperfusion. Free Radic Biol Med 2003; 35:1051-1063.
24. Buss H, Chan TP, Sluis KB, Domigan NM, Winterbourn CC. Protein carbonyl measurement by a sensitive ELISA method. Free Radic Biol Med 1997;23:361-366.
25. Zhong Z, Connor HD, Froh M, Bunzendahl H, Lind H, Lehnert M, et al. Free radical-dependent dysfunction of small-for-size rat liver grafts: prevention by plant polyphenols. Gastroenterology 2005;129:652-664.
26. Liang TB, Man K, Lee TKW, Tsui SHT, Lo CM, Xu Y. et al. Distinct intragraft response pattern in relation to graft size in liver transplantation. Transplantation 2003;75:673-678.
27. Troisi R, Cammu G, Militerno G, De Baerdemaeker L, Decruyenaere J, Hoste E, et al. Modulation of portal graft inflow: a necessity in adult living-donor liver transplantation? Ann Surg 2003;237:429-436.
28. Safadi R, Ohta M, Alvarez CE, Fiel MI, Bansal M, Mehal WZ, Friedman SL. Immune stimulation of hepatic fibrogenesis by CD8 cells and attenuation by transgenic interleukin-10 from hepatocytes. Gastroenterology 2004;127: 870-882.
29. Oreopoulos GD, Wu H, Szaszi K, Fan J, Marshall JC, Khadaroo RG, et al. Hypertonic preconditioning prevents hepatocellular injury following ischemia/reperfusion in mice: a role for interleukin 10. Hepatology 2004;40:211-220.
30. Chen D, Ding Y, Zhang N, Schroppel B, Fu S, Zang W, et al. Viral IL-10 gene transfer inhibits the expression of multiple chemokine and chemokine receptor genes induced by inflammatory or adaptive immune stimuli. Am J Transplant 2003;3:1538-1549.
31. Gong N, Pleyer U, Volk HD, Ritter T. Effects of local and systemic viral interleukin-10 gene transfer on corneal allograft survival. Gene Ther (in press).