Delay of acute intracellular pH recovery after acidosis decreases endothelial cell activation

Journal of Cellular Physiology

Volumn 211, Issue 2, 2007, Pages 399-409

  Huck, Volker ^a   Niemeyer, André ^a   Goerge, Tobias ^a   Schnaeker, Eva Maria ^a   Ossig, Rainer ^a   Rogge, Phillip ^a   Schneider, Matthias F ^b   Oberleithner, Hans ^a   Schneider, Stefan W ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY OF AUGSBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BUFFER; CALCIUM ION; CARIPORIDE; INTERLEUKIN 8; PADGEM PROTEIN; RINGER SOLUTION; SODIUM PROTON EXCHANGE PROTEIN 1; VON WILLEBRAND FACTOR;

ACIDOSIS; ALKALINIZATION; ARTICLE; CALCIUM CELL LEVEL; CELL ACTIVATION; CELL PH; CONTROLLED STUDY; ENDOTHELIUM CELL; EXOCYTOSIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN SECRETION; SECOND MESSENGER; SHEAR FLOW; THROMBOCYTE ADHESION; UMBILICAL VEIN;

ACIDOSIS; AMILORIDE; CALCIUM; CELL ADHESION; CELLS, CULTURED; CHLORIDE-BICARBONATE ANTIPORTERS; CYCLIC AMP; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; EXOCYTOSIS; GUANIDINES; HISTAMINE; HUMANS; HYDROGEN-ION CONCENTRATION; INTERLEUKIN-8; INTRACELLULAR FLUID; KINETICS; LINEAR MODELS; METHACRYLATES; P-SELECTIN; PLATELET ADHESIVENESS; REPERFUSION INJURY; SODIUM-HYDROGEN ANTIPORTER; SULFONES; UMBILICAL VEINS; VON WILLEBRAND FACTOR;

EID: 34247202662     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.20947     Document Type: Article

References (47)

1. An J, Varadarajan SG, Camara A, Chen Q, Novalija E, Gross GJ, Stowe DF. 2001. Blocking Na(+)/H(+) exchange reduces [Na(+)](i) and [Ca(2+)](i) load after ischemia and improves function in intact hearts. Am J Physiol Heart Circ Physiol 281:H2398-H2409.
2. Batlle DC, Peces R, LaPointe MS, Ye M, Daugirdas JT. 1993. Cytosolic free calcium regulation in response to acute changes in intracellular pH in vascular smooth muscle. Am J Physiol 264:C932-C943.
3. Boudreault F, Grygorczyk R. 2004. Cell swelling-induced ATP release is tightly dependent on intracellular calcium elevations. J Physiol 561:499-513.
4. Carden DL, Granger DN. 2000. Pathophysiology of ischaemia-reperfusion injury. J Pathol 190:255-266.
5. Cines DB, Pollak ES, Buck CA, Loscalzo J, Zimmerman GA, McEver RP, Pober JS, Wick TM, Konkle BA, Schwartz BS, Barnathan ES, McCrae KR, Hug BA, Schmidt AM, Stern DM. 1998. Endothelial cells in physiology and in the pathophysiology of vascular disorders. Blood 91:3527-3561.
6. Cooper D, Chitman KD, Williams MC, Granger DN. 2003. Time-dependent platelet-vessel wall interactions induced by intestinal ischemia-reperfusion. Am J Physiol Gastrointest Liver Physiol 284:G1027-G1033.
7. Datta YH, Ewenstein BM. 2001. Regulated secretion in endothelial cells: Biology and clinical implications. Thromb Haemost 86:1148-1155.
8. -/. Cell Physiol Biochem 8:202-211.
9. Gnaiger E, Kuznetsov AV, Rieger G, Amberger A, Fuchs A, Stadlmann S, Eberl T, Margreiter R. 2000. Mitochondrial defects by intracellular calcium overload versus endothelial cold ischemia/reperfusion injury. Transpl Int 13:5555-5557.
10. Goerge T, Niemeyer A, Rogge P, Ossig R, Oberleithner H, Schneider SW. 2002. Secretion pores in human endothelial cells during acute hypoxia. J Membr Biol 187:203-211.
11. Goerge T, Barg A, Schnaeker EM, Poppelmann B. Shpacovitch V, Rattenholl A, Maaser C, Luger TA, Steinhoff M, Schneider SW. 2006. Tumor-derived matrix metalloproteinase-1 targets endothelial proteinase-activated receptor 1 promoting endothelial cell activation. Cancer Res 66:7766-7774.
12. Granger DN, Vowinkel T, Petnehazy T. 2004. Modulation of the inflammatory response in cardiovascular disease. Hypertension 43:924-931.
13. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450.
14. Guttenberg Z, Rathgeber A, Keller S, Radler JO, Wixforth A, Kostur M, Schindler M, Talkner P. 2004. Flow profiling of a surface-acoustic-wave nanopump. Phys Rev E Stat Nonlin Soft Matter Phys 70:056311.
15. 2+ associated with von Willebrand factor release in human endothelial cells exposed to histamine. Study of microcarrier cell monolayers using the fluorescent probe indo-1. J Clin Invest 79:600-608.
16. Hannah MJ, Williams R, Kaur J, Hewlett LJ, Cutler DF. 2002. Biogenesis of Weibel-Palade bodies. Semin Cell Dev Biol 13:313-324.
17. + exchange by cariporide reduces Na(+)-overload in ischemia and is cardioprotective. J Mol Cell Cardiol 31:1985-1995.
18. Hropot M, Juretschke HP, Langer KH, Schwark JR. 2001. S3226, a novel NHE3 inhibitor, attenuates ischemia-induced acute renal failure in rats. Kidney Int 60:2283-2289.
19. Hu Q, Ziegelstein RC. 2000. Hypoxia/reoxygenation stimulates intracellular calcium oscillations in human aortic endothelial cells. Circulation 102:2541-2547.
20. Jakab M, Furst J, Gschwentner M, Botta G, Garavaglia ML, Bazzini C, Rodighiero S, Meyer G, Eichmueller S, Woll E, Chwatal S, Ritter M, Paulmichl M. 2002. Mechanisms sensing and modulating signals arising from cell swelling. Cell Physiol Biochem 12:235-258.
21. + exchanger: A potential therapeutic target for the prevention of myocardial ischaemic and reperfusion injury and attenuation of postinfarction heart failure. Drugs 61:375-389.
22. Ladilov Y, Schafer C, Held A, Schafer M, Noll T, Piper HM. 2000. Mechanism of Ca(2+) overload in endothelial cells exposed to simulated ischemia. Cardiovasc Res 47:394-403.
23. Levi M, ten Cate H, van der PT. 2002. Endothelium: Interface between coagulation and inflammation. Crit Care Med 30:S220-S224.
24. Linz WJ, Busch AE. 2003. NHE-1 inhibition: From protection during acute ischaemia/reperfusion to prevention/reversal of myocardial remodelling. Naunyn Schmiedebergs. Arch Pharmacol 368:239-246.
25. Lopes AA, Peranovich TM, Maeda NY, Bydlowski SP. 2001. Differential effects of enzymatic treatments on the storage and secretion of von Willebrand factor by human endothelial cells. Thromb Res 101:291-297.
26. Masereel B, Pochet L, Laeckmann D. 2003. An overview of inhibitors of Na(+)/H(+) exchanger. Eur J Med Chem 38:547-554.
27. Massberg S, Enders G, Leiderer R, Eisenmenger S, Vestweber D, Krombach F, Messmer K. 1998. Platelet-endothelial cell interactions during ischemia/reperfusion: The role of P-selectin. Blood 92:507-515.
28. Michaux G, Cutler DF. 2004. How to roll an endothelial cigar: The biogenesis of weibel-palade bodies. Traffic 5:69-78.
29. Michiels C. 2003. Endothelial cell functions. J Cell Physiol 196:430-443.
30. Nathan C. 2002. Points of control in inflammation. Nature 420:846-852.
31. Nilius B, Droogmans G. 2001. Ion channels and their functional role in vascular endothelium. Physiol Rev 81:1415-1459.
32. Nilius B, Prenen J, Droogmans G. 1998. Modulation of volume-regulated anion channels by extra- and intracellular pH. Pflugers Arch 436:742-748.
33. 2+]i mobilization in human pulmonary artery endothelial cells. J Appl Physiol 90:2094-2100.
34. Pearson JD. 2000. Normal endothelial cell function. Lupus 9:183-188.
35. Pinsky DJ, Naka Y, Liao H, Oz MC, Wagner DD, Mayadas TN, Johnson RC, Hynes RO, Heath M, Lawson CA, Stern DM. 1996. Hypoxia-induced exocytosis of endothelial cell Weibel-Palade bodies. A mechanism for rapid neutrophil recruitment after cardiac preservation. J Clin Invest 97:493-500.
36. Stromer H, de Groot MC, Horn M, Faul C, Leupold A, Morgan JP, Scholz W, Neubauer S. 2000. Na(+)/H(+) exchange inhibition with HOE642 improves postischemic recovery due to attenuation of Ca(2+) overload and prolonged acidosis on reperfusion. Circulation 101:2749-2755.
37. Sun B, Vaughan-Jones RD, Kambayashi J. 1999. Two distinct HCO(-)(3)-dependent H(+) efflux pathways in human vascular endothelial cells. Am J Physiol 277:H28-H32.
38. + exchange blockers EIPA, cariporide and eniporide. Mol Cell Biochem 250:47-54.
39. van der Wijk T, Tomassen SF, Houtsmuller AB, de Jonge HR, Tilly BC. 2003. Increased vesicle recycling in response to osmotic cell swelling. Cause and consequence of hypotonicity-provoked ATP release. J Biol Chem 278:40020-40025.
40. Van Mourik JA, Romani DW. 2001. Von Willebrand factor propeptide in vascular disorders. Thromb Haemost 86:164-171.
41. Vischer UM, de Moerloose P. 1999. von Willebrand factor: From cell biology to the clinical management of von Willebrand's disease. Crit Rev Oncol Hematol 30:93-109.
42. 2+ and cyclic adenosine monophosphate-dependent signaling in endothelial exocytosis. Blood 91:118-127.
43. Wagner DD. 1990. Cell biology of von Willebrand factor. Annu Rev Cell Biol 6:217-246.
44. Weibel ER, Palade GE. 1964. New cytoplasmic components in arterial endothelia. J Cell Biol 23:101-112.
45. Wong P, Kleemann HW, Tannock IF. 2002. Cytostatic potential of novel agents that inhibit the regulation of intracellular pH. Br J Cancer 87:238-245.
46. Ziegelstein RC, Cheng L, Blank PS, Spurgeon HA, Lakatta EG, Hansford RG, Capogrossi MC. 1993. Modulation of calcium homeostasis in cultured rat aortic endothelial cells by intracellular acidification. Am J Physiol 265:H1424-H1433.
47. Zupancic G, Ogden D, Magnus CJ, Wheeler-Jones C, Carter TD. 2002. Differential exocytosis from human endothelial cells evoked by high intracellular Ca(2+) concentration. J Physiol 544:741-755.