Inhibition of tumor growth in mice by endostatin derived from abdominal transplanted encapsulated cells

Acta Biochimica et Biophysica Sinica

Volumn 39, Issue 4, 2007, Pages 278-284

  Teng, Huaining ^a,c   Zhang, Ying ^b   Wang, Wei ^b   Ma, Xiaojun ^b   Fei, Jian ^a  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^b DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

CHO; Endostatin; Gene therapy; Microencapsulation; Tumor

Indexed keywords

ALGINATE POLYLYSINE ALGINATE; ALGINIC ACID; ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; BIOMATERIAL; COLLAGEN TYPE 18; DRUG DERIVATIVE; ENDOSTATIN; PEPTIDE FRAGMENT; POLYLYSINE;

ANIMAL; ARTICLE; C57BL MOUSE; CANCER TRANSPLANTATION; CELL CULTURE; CHO CELL; CRICETULUS; DISEASE MODEL; DRUG EFFECT; EXPERIMENTAL MELANOMA; FEMALE; GENE VECTOR; GENETIC TRANSFECTION; GENETICS; HAMSTER; HUMAN; MICROCAPSULE; MOUSE; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; PERITONEAL CAVITY; SECRETION; TRANSPLANTATION; TUMOR VOLUME; VASCULARIZATION; XENOGRAFT;

ALGINATES; ANGIOGENESIS INHIBITORS; ANIMALS; ANTINEOPLASTIC AGENTS; BIOCOMPATIBLE MATERIALS; CAPSULES; CHO CELLS; COLLAGEN TYPE XVIII; CRICETINAE; CRICETULUS; DISEASE MODELS, ANIMAL; ENDOSTATINS; FEMALE; GENETIC VECTORS; HUMANS; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; PEPTIDE FRAGMENTS; PERITONEAL CAVITY; POLYLYSINE; TRANSFECTION; TRANSPLANTATION, HETEROLOGOUS; TUMOR BURDEN; TUMOR CELLS, CULTURED;

CRICETULUS GRISEUS; MUS;

EID: 34247188017     PISSN: 16729145     EISSN: 17457270     Source Type: Journal    
DOI: 10.1111/j.1745-7270.2007.00273.x     Document Type: Article

References (36)

1. Folkman J, Cole P, Zimmerman S. Tumor behavior in isolated perfused organs: In vitro growth and metastases of biopsy material in rabbit thyroid and canine intestinal segment. Ann Surg 1966, 164: 491-502
2. Langer R. Control of tumor growth in animals by infusion of an angiogenesis inhibitor. Proc Natl Acad Sci USA 1980, 77: 4331-4335
3. O'Reilly MS, Boehm T, Shing Y, Fukai N, Vasios G, Lane WS, Flynn E et al. Endostatin: An endogenous inhibitor of angiogenesis and tumor growth. Cell 1997, 88: 277-285
4. Sim BK. Angiostatin and endostatin: Endothelial cell-specific endogenous inhibitors of angiogenesis and tumor growth. Angiogenesis 1998, 2: 37-48
5. Boehm T, Folkman J, Browder T, O'Reilly MS. Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance. Nature 1997, 390: 404-407
6. Joki T, Machluf M, Atala A, Zhu J, Seyfried NT, Dunn IF, Abe T et al. Continuous release of endostatin from microencapsulated engineered cells for tumor therapy. Nat Biotechnol 2001, 19: 35-39
7. Read TA, Sorensen DR, Mahesparan R, Enger PO, Timpl R, Olsen BR, Hjelstuen MH et al. Local endostatin treatment of gliomas administered by microencapsulated producer cells. Nat Biotechnol 2001, 19: 29-34
8. Sim BK, Fogler WE, Zhou XH, Liang H, Madsen JW, Luu K, O'Reilly MS et al. Zinc ligand-disrupted recombinant human endostatin: Potent inhibitor of tumor growth, safety and pharmacokinetic profile. Angiogenesis 1999, 3: 41-51
9. Dhanabal M, Ramchandran R, Volk R, Stillman IE, Lombardo M, Iruela-Ape ML, Simons M et al. Endostatin: Yeast production, mutants and antitumor effect in renal cell carcinoma. Cancer Res 1999, 59: 189-197
10. Yamaguchi N, Anand-Apte B, Lee M, Sasaki T, Fukai N, Shapiro R, Que I et al. Endostatin inhibitors VEGF-induced endothelial cell migration and tumor growth independently of zinc binding. EMBO J 1999, 18: 4414-4423
11. Taddei L, Chiarugi P, Brogelli L, Cirri P, Magnelli L, Raugei G, Ziche M et al. Inhibitory effect of full-length human endostatin on in vitro angiogenesis. Biochem Biophys Res Commun 1999, 63: 340-345
12. Dhanabal M, Volk R, Ramchandran R, Simons M, Sukhatme VP. Cloning, expression, and in vitro activity of human endostatin. Biochem Biophys Res Commun 1999, 258: 345-352
13. Yokoyama Y, Dhanabal M, Griffioen AW, Sukhatme VP, Ramakrishnan S. Synergy between angiostatin and endostatin: Inhibition of ovarian cancer growth. Cancer Res 2000, 60: 2190-2196
14. Kulke MH, Bergsland EK, Ryan DP, Enzinger PC, Lynch TJ, Zhu AX, Meyerhardt JA et al. Phase II study of recombinant human endostatin in patients with advanced neuroendocrine tumors. J Clin Oncol 2006, 24: 3555-3561
15. Perletti G, Concari P, Giardini R, Marras E, Piccinini F, Folkman J, Chen L. Antitumor activity of endostatin against carcinogen-induced rat primary mammary tumors. Cancer Res 2000, 60: 1793-1796
16. Kisker O, Becker CM., Prox D, Fannon M, D'Amato R, Flynn E, Fogler WE et al. Continuous administration of endostatin by intraperitoneally implanted osmotic pump improves the efficacy and potency of therapy in a mouse xenograft tumor model. Cancer Res 2001, 61: 7669-7674
17. Lim F, Sun AM. Microencapsulated islets as bioartificial endocrine pancreas. Science 1980, 210: 908-910
18. Soon-Shiong P, Heintz RE, Merideth N, Yao QX, Yao Z, Zheng T, Murphy M et al. Insulin independence in a type 1 diabetic patient after encapsulated islets transplantation. Lancet 1994, 143: 950-955
19. Lanza RP, Hayes JL, Chick WL. Encapsulated cell technology. Nat Biotechnol 1996, 14: 1107-1111
20. Ma X, Vacek I, Sun A. Generation of alginate-poly-l-lysine-alginate (APA) biomicrocapsules: The relationship between the membrane strength and the reaction conditions. Artif Cells Blood Substit Immobil Biotechnol 1994, 22: 43-69
21. Martinsen A, Storrø I, Skjak-Braek G. Alginate as immobilization material: III. Diffusional properties. Biotechnol Bioeng 1992, 39: 186-194
22. Sasaki T, Larsson H, Kreuger J, Salmivirta M, Claesson-Welsh L, Lindahl U, Hohenester E et al. Structural basis and potential role of heparin/heparan sulfate binding to the angiogenesis inhibitor endostatin. EMBO J 1999, 18: 6240-6248
23. Martinico SC, Jezzard S, Sturt NJ, Michils G, Tejpar S, Phillips RK, Vassaux G. Assessment of endostatin gene therapy for familial adenomatous polyposis-related desmoid tumors. Cancer Res 2006, 66: 8233-8240
24. Dkhissi F, Lu H, Soria C, Opolon P, Griscelli F, Liu H, Khattar P et al. Endostatin exhibits a direct antitumor effect in addition to its antiangiogenic activity in colon cancer cells. Hum Gene Ther 2003, 14: 997-1008
25. + T cell-mediated eradication of established tumors by peritumoral injection of CpG-containing oligodeoxynucleotides. J Immunol 2001, 167: 5247-5253
26. Schmidt NO, Ziu M, Carrabba G, Giussani C, Bello L, Sun Y, Schmidt K et al. Intravital microscopy reveals novelantivascular and antitumor effects of endostatin delivered locally by alginate-encapsulated cells. Cancer Res 2001, 61: 6830-6837
27. Davis MW, Vacanti JP. Toward development of an implantable tissue engineered liver. Biomaterials 1996, 17: 365-372
28. Hamazaki K, Doi Y, Koide N. Microencapsulated multicellular spheroid of rat hepatocytes transplanted intraperitoneally after 90% hepatectomy. Hepatogastroenterology 2002, 49: 1514-1516
29. Hasse C, Bohrer T, Barth P, Stinner B, Cohen R, Cramer H, Zimmermann U et al. Parathyroid xenotransplantation without immunosuppression in experimental hypoparathyroidism: Long-term in vivo function following microencapsulation with a clinically suitable alginate. World J Surg 2000, 24: 1361-1366
30. Hasse C, Klock G, Schlosser A, Zimmermann U, Rothmund M. Parathyroid allotransplantation without immunosuppression. Lancet 1997, 350: 1296-1297
31. Tai IT, Sun AM. Microencapsulation of recombinant cells: A new delivery system for gene therapy. FASEB J 1993, 7: 1061-1069
32. Chang PL, Van Raamsdonk JM, Hortelano G, Barsoum SC, MacDonald NC, Stockley TL. The in vivo delivery of heterologous proteins by microencapsulated recombinant cells. Trends Biotechnol 1999, 17: 78-83
33. De Vos P, De Haan BJ, Wolters GH, Strubbe JH, van Schilfgaarde R. Improved biocompatibility but limited graft survival after purification of alginate for microencapsulation of pancreatic islets. Diabetologia 1997, 40: 262
34. Soon-Shiong P, Otterlie M, Skjak-Braek G, Smidsrod O, Heintz R, Lanza RP, Espevik T. An immunological basis for the fibrotic reaction to implanted microcapsules. Transplant Proc 1991, 23: 758-759
35. Clayton HA, London NJ, Colloby PS, Bell PR, James RF. The effect of capsule composition on the biocompatibility of alginate-poly-l-lysine capsules. J Microencapsulation 1991, 8: 221-233
36. Ching D, Charles K, Harland RC, Opara EC. Microencapsulation of cryopreserved islets for transplantation. Current Surgery 1999, 56: 383