Antitumor activity of endostatin against carcinogen-induced rat primary mammary tumors

Cancer Research

Volumn 60, Issue 7, 2000, Pages 1793-1796

  Perletti, Gianpaolo ^a   Concari, Paola ^a   Giardini, Roberto ^b   Marras, Emanuela ^a   Piccinini, Francesco ^a   Folkman, Judah ^c   Chen, Longchuan ^c  

^a UNIVERSITY OF INSUBRIA   (Italy)

^b NATIONAL CANCER INSTITUTE   (Italy)

^c BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7,12 DIMETHYLBENZ[A]ANTHRACENE; ANTINEOPLASTIC AGENT; CARCINOGEN; COLLAGEN; COLLAGEN TYPE 18; ENDOSTATIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CARCINOMA; CANCER INHIBITION; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; MOLECULAR CLONING; MULTIPLE CANCER; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; TUMOR VOLUME;

9,10-DIMETHYL-1,2-BENZANTHRACENE; AMINO ACID SEQUENCE; ANIMALS; ANTINEOPLASTIC AGENTS; BASE SEQUENCE; CARCINOGENS; COLLAGEN; COLLAGEN TYPE XVIII; ENDOSTATINS; FEMALE; HUMANS; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0034074561     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Folkman, J. Tumor angiogenesis: therapeutic implications. N. Engl. J. Med., 18: 285:1182-1186, 1971.
2. Hanahan, D., and Folkman, J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell, 86: 353-364, 1996.
3. O'Reilly, M. S., Boehm, T., Shing Y., Fukai N., Vasios G., Lane W. S., Flynn E., Birkhead J., Olsen B., and Folkman J. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell, 88: 277-285, 1997.
4. Boehm, T., Folkman, J., Browder, T., and O'Reilly, M. Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance. Nature (Lond.), 390: 404-407, 1997.
5. Sasaki, T., Fukai, N., Mann, K., Goehring, W., Olsen, B. R., and Timpl, R. Structure, function and tissue forms of the C-terminal globular domain of collagen XVIII containing the angiogenesis inhibitor endostatin. EMBO J., 17: 4249-4256, 1998.
6. Welsch, C. W. Host factors affecting the growth of carcinogen-induced rat mammary carcinomas: a review and tribute to Charles Brenton Huggins. Cancer Res., 45: 3415-3443, 1985.
7. Huggins, C., Grand, L. C., and Brillantes, F. Mammary cancer induced by a single feeding of polynuclear hydrocarbons, and its suppression. Nature (Lond.), 189: 204-207, 1961.