Physiologic function of IK1 requires a combination of Kir2 isoforms

Heart Rhythm

Volumn 4, Issue 4, 2007, Pages 497-498

  Rook, Martin B ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; INWARDLY RECTIFYING POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.1; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.2; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.3; ISOPROTEIN; POTASSIUM CHANNEL; POTASSIUM CHANNEL HERG; POTASSIUM CHANNEL KVLQT1; PROTEIN KINASE C; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL;

ACIDOSIS; ALKALOSIS; ANDERSEN SYNDROME; BONE DISEASE; CELL PH; CELL STRAIN HEK293; EDITORIAL; EXTRACELLULAR SPACE; FACE MALFORMATION; FINGER MALFORMATION; GENE MUTATION; GENETIC TRANSFECTION; HEART ARRHYTHMIA; HEART ATRIUM; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; HEART REPOLARIZATION; HEART VENTRICLE; HEART VENTRICLE FIBRILLATION; HUMAN; INTRACELLULAR SPACE; LONG QT SYNDROME; MYOBLAST; MYOTUBE; NONHUMAN; PARALYSIS; POTASSIUM CONDUCTANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; SCOLIOSIS; SHORT STATURE; STOICHIOMETRY;

ANIMALS; ELECTROPHYSIOLOGY; HEART VENTRICLES; HYDROGEN-ION CONCENTRATION; MYOCYTES, CARDIAC; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN ISOFORMS;

EID: 34247183031     PISSN: 15475271     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hrthm.2006.12.041     Document Type: Editorial

References (24)

1. Nichols C.G., and Lopatin A.N. Inward rectifier potassium channels. Annu Rev Physiol 59 (1997) 171-191
2. K1. J Mol Cell Cardiol 33 (2001) 625-638
3. Schram G., Pourrier M., Wang Z., White M., and Nattel S. Barium block of Kir2.1 and human cardiac inward rectifier currents: evidence for subunit-heteromeric contribution to native currents. Cardiovasc Res 59 (2003) 328-338
4. K1) controls cardiac excitability and is involved in arrhythmogenesis. Heart Rhythm 2 (2005) 316-324
5. Wang Z., Yue L., White M., Pelletier G., and Nattel S. Differential distribution of inward rectifier potassium channel transcripts in human atrium versus ventricle. Circulation 98 (1998) 2411-2428
6. + current. Circ Res 94 (2004) 1332-1339
7. + channels by proton-mediated interactions of intracellular protein domains. Cardiovasc Med 12 (2002) 5-13
8. Muñoz V., Vaidyanathan R., Tolkacheva E.G., Dhamoon A.S., Taffet S.M., and Anumonwo J.M.B. Kir2.3 isoform confers pH sensitivity to heteromeric Kir2.1/Kir2.3 channels in HEK293 cells. Heart Rhythm 4 (2007) 487-496
9. Kass R.S. The channelopathies: novel insights into molecular and genetic mechanisms of human disease. J Clin Invest 115 (2005) 1986-1989
10. George A.L. Inherited disorders of voltage-gated sodium channels. J Clin Invest 115 (2005) 1990-1999
11. Modell S.M., and Lehmann M.H. The long QT syndrome family of cardiac ion channelopathies: a HuGE review. Genet Med 8 (2006) 143-155
12. Andersen E.D., Krasilnikoff P.A., and Overvad H. Intermittent muscular weakness, extrasystoles, and multiple developmental anomalies. A new syndrome?. Acta Paediatr Scand 60 (1971) 559-564
13. Tawil R., Ptácek L.J., Pavlakis S.G., De Vivo D.C., Penn A.S., Ozdemir C., and Griggs R.C. Anderson's syndrome: potassium-sensitive periodic paralysis, ventricular ectopy, and dysmorphic features. Ann Neurol 35 (1994) 326-330
14. Donaldson M.R., Yoon G., Fu Y.H., and Ptácek L.J. Andersen-Tawil syndrome: a model of clinical variability, pleiotropy, and genetic heterogeneity. Ann Med 36 Suppl 1 (2004) 92-97
15. Fisher L.J., Liu H., Espinos E., Moradasini D., Bader C., Belin D., and Bernheim L. Human myoblast fusion requires expression of functional inward rectifier Kir2.1 channels. J Cell Biol 153 (2001) 677-686
16. Gaita F., Giustetto C., Biabchi F., Wolpert C., Schimpf R., Riccardi R., Grossi S., Richiardi E., and Borggrefe M. Short QT syndrome: a familial cause of sudden death. Circulation 108 (2003) 965-970
17. Borggrefe M., Wolpert C., Antzelevitch C., Veltmann C., Giustetto C., Gaita F., and Schimpf R. Short QT-syndrome. Genotype-phenotype correlations. J Electrocardiol 38 (2005) 75-80
18. Priori S.G., Pandit S.V., Rivolta I., Berenfeld O., Ronchetti E., Dhamoon A., Napolitano C., Anumonwo J., di Barletta M.R., Gudapakkam A., Bosi G., Stramba-Badiale M., and Jalife J. A novel form of short QT syndrome is (SQT3) is caused by a mutation in the KCNJ2 gene. Circ Res 96 (2005) 800-807
19. Zhu G., Ou Z., Cui N., and Jiang C. Suppression of Kir2.3 activity by protein kinase C phosphorylation of the channel protein at threonine 53. J Biol Chem 274 (1999) 11643-11646
20. Kir2.2 is upregulated by activation of protein kinase A. Cardiovasc Res 63 (2004) 520-527
21. + channels by shift of intracellular pH dependence. J Cell Physiol 202 (2005) 76-86
22. Panama B.K., and Lopatin A.N. Differential polyamine sensitivity of inwardly rectifying Kir2 potassium channels. J Physiol 571.2 (2006) 287-302
23. K1 and Kir2.x channels by endothelin-1. J Mol Med 84 (2006) 46-56
24. Warren M., Guha P.K., Berenfeld O., Zaitsev A., Anumonwo J.M., Dhamoon A.S., Bagwe S., Taffet S.M., and Jalife J. Blockade of the inward rectifying potassium current terminates ventricular fibrillation in the guinea pig heart. J Cardiovasc Electrophysiol 14 (2003) 621-631