In vivo antimalarial activity of aqueous extracts from Kenyan medicinal plants and their chloroquine (CQ) potentiation effects against a blood-induced CQ-resistant rodent parasite in mice

Phytotherapy Research

Volumn 21, Issue 4, 2007, Pages 337-343

  Muregi, Francis W ^a   Ishih, Akira ^a   Suzuki, Tohru ^a   Kino, Hideto ^a   Amano, Teruaki ^c   Mkoji, Gerald M ^c   Miyase, Toshio ^b   Terada, Mamoru ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF SHIZUOKA   (Japan)

^c KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

Author keywords

CQ resistance; Drug combination; Medicinal plants; Plasmodium berghei NK65; Synergistic effects; Traditional medicine

Indexed keywords

CHLOROQUINE; MAYTENUS ACUMINATA EXTRACT; MAYTENUS HETEROPHYLLA EXTRACT; MAYTENUS SENEGALENSIS EXTRACT; PLANT EXTRACT; RHAMNUS EXTRACT; RHAMNUS PRINOIDES EXTRACT; RHAMNUS STADDO EXTRACT; TODDALIA ASIATICA EXTRACT; UNCLASSIFIED DRUG; VERNONIA LASIOPUS EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; BARK; CONTROLLED STUDY; DRUG ISOLATION; DRUG POTENTIATION; DRUG SCREENING; IN VIVO STUDY; KENYA; MALARIA; MALE; MAYTENUS; MAYTENUS ACUMINATA; MAYTENUS HETEROPHYLLA; MAYTENUS SENEGALENSIS; MOUSE; NONHUMAN; PARASITEMIA; PLANT LEAF; PLANT ROOT; PLASMODIUM BERGHEI; RHAMNUS; RHAMNUS PRINOIDES; RHAMNUS STADDO; RUTACEAE; TODDALIA ASIATICA; VERNONIA; VERNONIA LASIOPUS;

ANIMALS; ANTIMALARIALS; CHLOROQUINE; DRUG RESISTANCE, MICROBIAL; DRUG SYNERGISM; KENYA; MALARIA; MALE; MICE; MICE, INBRED ICR; PHYTOTHERAPY; PLANT EXTRACTS; PLANTS, MEDICINAL; PLASMODIUM BERGHEI;

MAYTENUS; MAYTENUS HETEROPHYLLA; MAYTENUS SENEGALENSIS; MUS; PLASMODIUM BERGHEI; RHAMNUS PRINOIDES; RHAMNUS STADDO; RODENTIA; TODDALIA ASIATICA; VERNONIA LASIOPUS; WITHANIA SOMNIFERA;

EID: 34247157838     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.2067     Document Type: Article

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