메뉴 건너뛰기




Volumn 25, Issue 2, 2007, Pages 117-123

6-Mercaptopurine (6-MP) entrapped stealth liposomes for improvement of leukemic treatment without hepatotoxicity and nephrotoxicity

Author keywords

6 Mercaptopurine; Biodistribution studies; Liposomes; Pharmacokinetic

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CHOLESTEROL; CREATININE; LIPOSOME; MACROGOL 2000; MERCAPTOPURINE; PHOSPHATIDYLCHOLINE; UREA;

EID: 34247157805     PISSN: 07357907     EISSN: 15324192     Source Type: Journal    
DOI: 10.1080/07357900701224862     Document Type: Article
Times cited : (16)

References (35)
  • 1
    • 0030795298 scopus 로고    scopus 로고
    • Liposomes in drug delivery: Progress and limitations
    • Sharma, A.; Sharma, U.S. Liposomes in drug delivery: progress and limitations. Int J. Pharm 1997, 154, 123-140.
    • (1997) Int J. Pharm , vol.154 , pp. 123-140
    • Sharma, A.1    Sharma, U.S.2
  • 2
    • 0036775616 scopus 로고    scopus 로고
    • Chemotherapeutic activity against murine tuberculosis of once weekly administered drugs (isoniazid and rifampicin) encapsulated in liposomes
    • Labana, S.; Pandey, R.; Sharma, S.; Khuller, G.K. Chemotherapeutic activity against murine tuberculosis of once weekly administered drugs (isoniazid and rifampicin) encapsulated in liposomes. Int. J. Antimicro. Agents 2002, 20, 301-304.
    • (2002) Int. J. Antimicro. Agents , vol.20 , pp. 301-304
    • Labana, S.1    Pandey, R.2    Sharma, S.3    Khuller, G.K.4
  • 3
    • 0021162146 scopus 로고
    • Reduced cardiotoxicity and nephrotoxicity with preservation of antitumor-activity of doxorubicin entrapped in stable liposomes in the LOU/M Wsl rats
    • Van Hoesel, Q.; Steerenberg, P.A.; Crommelin, D.J.; Vandijk, A.; Vanoort, W.; Klein, S. Reduced cardiotoxicity and nephrotoxicity with preservation of antitumor-activity of doxorubicin entrapped in stable liposomes in the LOU/M Wsl rats. Cancer Res. 1984, 44, 3698-3705.
    • (1984) Cancer Res , vol.44 , pp. 3698-3705
    • Van Hoesel, Q.1    Steerenberg, P.A.2    Crommelin, D.J.3    Vandijk, A.4    Vanoort, W.5    Klein, S.6
  • 4
    • 0027207067 scopus 로고
    • Liposomal applications to cancer therapy
    • Namba, Y.; Oku, N. Liposomal applications to cancer therapy, J. Bioact. Compat. Polym. 1993, 8, 158-177.
    • (1993) J. Bioact. Compat. Polym , vol.8 , pp. 158-177
    • Namba, Y.1    Oku, N.2
  • 5
    • 0036255563 scopus 로고    scopus 로고
    • Teratogen update: Azathioprine and 6-mercaptopurine
    • Janine, E.; Friedman, J.M. Teratogen update: azathioprine and 6-mercaptopurine. Teratology 2002, 65, 240-261.
    • (2002) Teratology , vol.65 , pp. 240-261
    • Janine, E.1    Friedman, J.M.2
  • 6
    • 9044230523 scopus 로고    scopus 로고
    • Clinical and experimental pharmacokinetic interaction between 6-mercaptopurine and methotrexate
    • Federico, I.; Antonello, D.P.; Barbara, L. Clinical and experimental pharmacokinetic interaction between 6-mercaptopurine and methotrexate. Cancer Chemother. Pharmacol. 1996, 37, 409-414.
    • (1996) Cancer Chemother. Pharmacol , vol.37 , pp. 409-414
    • Federico, I.1    Antonello, D.P.2    Barbara, L.3
  • 7
    • 0024428165 scopus 로고
    • 6-Mercaptopurine plasma levels in children with acute lymphoblastic leukemia: Relation to relapse risk and myelotoxicity
    • Hayder, S.; Lafolie, P.; Bjork, O.; Peterson, C. 6-Mercaptopurine plasma levels in children with acute lymphoblastic leukemia: relation to relapse risk and myelotoxicity. Ther. Drug Monit. 1989, 11, 617-622.
    • (1989) Ther. Drug Monit , vol.11 , pp. 617-622
    • Hayder, S.1    Lafolie, P.2    Bjork, O.3    Peterson, C.4
  • 8
    • 0022538388 scopus 로고
    • Large interindividual variations in the pharmacokinetics of oral 6-mercaptopurine in maintenance therapy of children with acute leukemia and non-Hodgkin's lymphoma
    • Lafolie, P.; Hayder, S.; Bjork, O.; Ahstrom, L.; Liliemark, J.; Peterson, C. Large interindividual variations in the pharmacokinetics of oral 6-mercaptopurine in maintenance therapy of children with acute leukemia and non-Hodgkin's lymphoma. Acta. Paediat. Scand. 1986, 75, 797-803.
    • (1986) Acta. Paediat. Scand , vol.75 , pp. 797-803
    • Lafolie, P.1    Hayder, S.2    Bjork, O.3    Ahstrom, L.4    Liliemark, J.5    Peterson, C.6
  • 9
    • 0022871348 scopus 로고
    • Influence of food intake on bioavailability of oral 6-mercaptopurine in children with acute lymphoblastic leukemia
    • Riccardi, R.; Balis, F.; Ferrara, P.; Lasorella, A.; Poplack, D.; Mastrangelo, R. Influence of food intake on bioavailability of oral 6-mercaptopurine in children with acute lymphoblastic leukemia. Pediatr. Hematol. Oncol. 1986, 3, 319-324.
    • (1986) Pediatr. Hematol. Oncol , vol.3 , pp. 319-324
    • Riccardi, R.1    Balis, F.2    Ferrara, P.3    Lasorella, A.4    Poplack, D.5    Mastrangelo, R.6
  • 10
    • 0023001398 scopus 로고
    • Pharmacokinetic determinations of 6-mercaptopurine myelotoxicity and therapeutic failure in children with acute lymphoblastic leukemia
    • Sulh, H.; Koren, G.; Whalen, C.; Soldin, S.; Zipursky, A.; Greenberg, M. Pharmacokinetic determinations of 6-mercaptopurine myelotoxicity and therapeutic failure in children with acute lymphoblastic leukemia. Clin. Pharmacol. Ther. 1986, 40, 604-609.
    • (1986) Clin. Pharmacol. Ther , vol.40 , pp. 604-609
    • Sulh, H.1    Koren, G.2    Whalen, C.3    Soldin, S.4    Zipursky, A.5    Greenberg, M.6
  • 11
    • 0020534019 scopus 로고
    • Variable bioavailability of oral mercaptopurine: Is maintenance chemotherapy in acute lymphoblastic leukemia being optimally delivered?
    • Zimm, S.; Collins, J.M.; Riccardi, R.; O'Neill, D.; Narang, P.K.; Chabner, B. Variable bioavailability of oral mercaptopurine: is maintenance chemotherapy in acute lymphoblastic leukemia being optimally delivered? N. Engl. J. Med. 1983, 308, 1005-1009.
    • (1983) N. Engl. J. Med , vol.308 , pp. 1005-1009
    • Zimm, S.1    Collins, J.M.2    Riccardi, R.3    O'Neill, D.4    Narang, P.K.5    Chabner, B.6
  • 12
    • 34248662937 scopus 로고    scopus 로고
    • Arulsudar, N.; Subramanian, N.; Mishra, P.; Murthy, R.S.R. Preparation, Characterization, and biodistribution study of Technetium-99m-labled leuprolide acetate loaded liposomes in ehrlich ascites tumor bearing mice, AAPS Pharm. Sci. 2004, 6 (1), article 5, 1-12.
    • Arulsudar, N.; Subramanian, N.; Mishra, P.; Murthy, R.S.R. Preparation, Characterization, and biodistribution study of Technetium-99m-labled leuprolide acetate loaded liposomes in ehrlich ascites tumor bearing mice, AAPS Pharm. Sci. 2004, 6 (1), article 5, 1-12.
  • 13
    • 0035838391 scopus 로고    scopus 로고
    • Evaluation of circulation profiles of liposomes coated with hydrophilic polymers having different molecular weights in rats
    • Takeuchi, H.; Kojima, H.; Yamamoto, H.; Kawashima, Y. Evaluation of circulation profiles of liposomes coated with hydrophilic polymers having different molecular weights in rats. J. Controlled Rel. 2001, 75, 83-91.
    • (2001) J. Controlled Rel , vol.75 , pp. 83-91
    • Takeuchi, H.1    Kojima, H.2    Yamamoto, H.3    Kawashima, Y.4
  • 14
    • 0032853891 scopus 로고    scopus 로고
    • Anticancer therapy using glucuronate modified longcirculating liposomes
    • Oku N. Anticancer therapy using glucuronate modified longcirculating liposomes, Adv. Drug Del. Rew. 1999, 40, 63-73.
    • (1999) Adv. Drug Del. Rew , vol.40 , pp. 63-73
    • Oku, N.1
  • 15
    • 0021029382 scopus 로고
    • Prevention of chronic doxorubicin cardiotoxicity in beagles by liposomal encapsulation
    • Herman, E.H.; Rahman, A.; Ferrans, V.J.; Vick, J.A.; Schein, P.S. Prevention of chronic doxorubicin cardiotoxicity in beagles by liposomal encapsulation. Cancer Res. 1983, 43, 5427-732.
    • (1983) Cancer Res , vol.43 , pp. 5427-5732
    • Herman, E.H.1    Rahman, A.2    Ferrans, V.J.3    Vick, J.A.4    Schein, P.S.5
  • 16
    • 0028349925 scopus 로고
    • Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes
    • Gabizon, A.; Catane, R.; Uziely, B. Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes. Cancer Res. 1994, 54, 987-92.
    • (1994) Cancer Res , vol.54 , pp. 987-992
    • Gabizon, A.1    Catane, R.2    Uziely, B.3
  • 17
    • 0032958135 scopus 로고    scopus 로고
    • Comparative pharmacokinetics, tissue distribution, and therapeutic effectiveness of cisplatin encapsulated in long circulating, pegylated liposomes (SPI-077) in tumor-bearing mice
    • Newman, M.S.; Colbern, G.T.; Working, P.K.; Engbers, C.; Amantea, M.A. Comparative pharmacokinetics, tissue distribution, and therapeutic effectiveness of cisplatin encapsulated in long circulating, pegylated liposomes (SPI-077) in tumor-bearing mice. Cancer Chemother. Pharmacol. 1999, 43, 1-7.
    • (1999) Cancer Chemother. Pharmacol , vol.43 , pp. 1-7
    • Newman, M.S.1    Colbern, G.T.2    Working, P.K.3    Engbers, C.4    Amantea, M.A.5
  • 18
    • 0027268663 scopus 로고
    • Comparative pharmacological, toxicological and antitumoral evaluation of free and liposome-encapsulated cisplatin in rodents
    • Gondal, J.A.; Preuss, H.G.; Swartz, R.; Rahman A. Comparative pharmacological, toxicological and antitumoral evaluation of free and liposome-encapsulated cisplatin in rodents. Eur. J. Cancer 1993, 29A, 1536-1542.
    • (1993) Eur. J. Cancer , vol.29 A , pp. 1536-1542
    • Gondal, J.A.1    Preuss, H.G.2    Swartz, R.3    Rahman, A.4
  • 19
    • 0032858556 scopus 로고    scopus 로고
    • Ishida, T.; Iden, D.; Allen, T. A combinatorial approach to producing sterically stabilized immunoliposomal drugs. FEBS Lett. 1999, 460, 129-133.
    • Ishida, T.; Iden, D.; Allen, T. A combinatorial approach to producing sterically stabilized immunoliposomal drugs. FEBS Lett. 1999, 460, 129-133.
  • 20
    • 85012373035 scopus 로고
    • Diffusion of univalent ions across the lamellae of swollen phospholipids
    • Bangham, A.D.; Standish, M.M.; Watkins, J.C. Diffusion of univalent ions across the lamellae of swollen phospholipids. J. Mol. Biol. 1965, 13, 238-252.
    • (1965) J. Mol. Biol , vol.13 , pp. 238-252
    • Bangham, A.D.1    Standish, M.M.2    Watkins, J.C.3
  • 22
    • 34247121696 scopus 로고
    • A spectrophotometric method for the estimation of urinary azathioprine, 6-mercaptopurine, and 6-thiouric acid
    • Chalmers, A.H. A spectrophotometric method for the estimation of urinary azathioprine, 6-mercaptopurine, and 6-thiouric acid. Biochem. Med. 1975, 16 (6), 513-515.
    • (1975) Biochem. Med , vol.16 , Issue.6 , pp. 513-515
    • Chalmers, A.H.1
  • 23
    • 0038641806 scopus 로고    scopus 로고
    • Preparation, optimization, characterization and stability studies of salicylic acid liposomes
    • Bhalerao, S.S.; Harshal, A.R. Preparation, optimization, characterization and stability studies of salicylic acid liposomes. Drug Dev. Ind. Pharm. 2003, 29 (4), 451-467.
    • (2003) Drug Dev. Ind. Pharm , vol.29 , Issue.4 , pp. 451-467
    • Bhalerao, S.S.1    Harshal, A.R.2
  • 26
    • 34247171128 scopus 로고    scopus 로고
    • Use of electrolyte induced flocculation technique for in-vitro steric stability of sterically stabilized liposomal formulation
    • Subramanian, N.; Murthy, R.S.R. Use of electrolyte induced flocculation technique for in-vitro steric stability of sterically stabilized liposomal formulation. Die Pharmazie 2004, 1, 69-74.
    • (2004) Die Pharmazie , vol.1 , pp. 69-74
    • Subramanian, N.1    Murthy, R.S.R.2
  • 27
    • 0028102168 scopus 로고
    • Effects of cremophor EL on distribution of Taxol to serum lipoproteins
    • Sykes, E.; Woodburn, K.; Decker, D.; Kessel, D. Effects of cremophor EL on distribution of Taxol to serum lipoproteins. Br. J. Cancer 1994, 70, 401-404.
    • (1994) Br. J. Cancer , vol.70 , pp. 401-404
    • Sykes, E.1    Woodburn, K.2    Decker, D.3    Kessel, D.4
  • 30
    • 9044230523 scopus 로고    scopus 로고
    • Clinical and experimental pharmacokinetic interaction between 6-mercaptopurine and methotrexate
    • Federico, I.; Antonello, D.P.; Barbara. L. Clinical and experimental pharmacokinetic interaction between 6-mercaptopurine and methotrexate. Cancer Chemother. Pharmacol. 1996, 37, 409-414.
    • (1996) Cancer Chemother. Pharmacol , vol.37 , pp. 409-414
    • Federico, I.1    Antonello, D.P.2    Barbara, L.3
  • 31
    • 0021028642 scopus 로고
    • Inhibition of first-pass metabolism in cancer chemotherapy: Interaction of 6-mercaptopurine and allopurinol
    • Zimm, S.; Collins, J.M.; O'Neill, D.; Chabner, B.A.; Poplack, D.G. Inhibition of first-pass metabolism in cancer chemotherapy: interaction of 6-mercaptopurine and allopurinol. Clin. Pharmacol. Ther. 1983, 34, 810-817.
    • (1983) Clin. Pharmacol. Ther , vol.34 , pp. 810-817
    • Zimm, S.1    Collins, J.M.2    O'Neill, D.3    Chabner, B.A.4    Poplack, D.G.5
  • 32
    • 0022551875 scopus 로고
    • Oral 6-mercaptopurine in childhood leukemia: Parent drug pharmacokinetics and active metabolite concentrations
    • Lennard, L.; Keen, D.; Lilleyman, J.S. Oral 6-mercaptopurine in childhood leukemia: parent drug pharmacokinetics and active metabolite concentrations. Clin. Pharmacol. Ther. 1986, 40, 287-292.
    • (1986) Clin. Pharmacol. Ther , vol.40 , pp. 287-292
    • Lennard, L.1    Keen, D.2    Lilleyman, J.S.3
  • 33
    • 0025331198 scopus 로고
    • Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukemia
    • Lennard, L.; Lilleyman, J.S.; Van Loon, J.; Weinshilboum, R.M. Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukemia. Lancet 1990, 336, 225-229.
    • (1990) Lancet , vol.336 , pp. 225-229
    • Lennard, L.1    Lilleyman, J.S.2    Van Loon, J.3    Weinshilboum, R.M.4
  • 34
    • 0024818659 scopus 로고
    • Variable 6-mercaptopurine metabolism and treatment outcome in childhood lymphoblastic leukemia
    • Lennard, L.; Lilleyman, J.S. Variable 6-mercaptopurine metabolism and treatment outcome in childhood lymphoblastic leukemia. J. Clin. Oncol. 1989, 7, 1816-1823.
    • (1989) J. Clin. Oncol , vol.7 , pp. 1816-1823
    • Lennard, L.1    Lilleyman, J.S.2
  • 35
    • 0842279809 scopus 로고
    • Liposomes formulation with prolonged circulation time in blood and enhance uptake by tumors
    • Gabizon, G.; Papahadjopoulos, D. Liposomes formulation with prolonged circulation time in blood and enhance uptake by tumors. Pro. Nat. Acad. Sci. USA. 1988, 85, 6949-6953.
    • (1988) Pro. Nat. Acad. Sci. USA , vol.85 , pp. 6949-6953
    • Gabizon, G.1    Papahadjopoulos, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.