Epidemiology, genes and the environment: Lessons learned from the Helsinki Birth Cohort Study

Journal of Internal Medicine

Volumn 261, Issue 5, 2007, Pages 418-425

  Eriksson, J G ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Coronary heart disease; Fetal growth; Genes; Infancy; Interactions; Obesity; Type 2 diabetes

Indexed keywords

INSULIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; SOMATOMEDIN C;

BODY MASS; BODY SIZE; CHILD GROWTH; CHILDHOOD; COHORT ANALYSIS; CONFERENCE PAPER; CORONARY RISK; FETUS GROWTH; FINLAND; GENOTYPE ENVIRONMENT INTERACTION; HEREDITY; HUMAN; INFANCY; ISCHEMIC HEART DISEASE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PATHOGENESIS; PRENATAL GROWTH; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; VARIABLE NUMBER OF TANDEM REPEAT;

ADOLESCENT; ADULT; CHILD; CHILD DEVELOPMENT; COHORT STUDIES; CORONARY DISEASE; DIABETES MELLITUS, TYPE 2; FEMALE; FETAL GROWTH RETARDATION; FINLAND; HUMANS; INFANT; INFANT, LOW BIRTH WEIGHT; INFANT, NEWBORN; INSULIN; MALE; OBESITY; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS;

EID: 34247149800     PISSN: 09546820     EISSN: 13652796     Source Type: Journal    
DOI: 10.1111/j.1365-2796.2007.01798.x     Document Type: Conference Paper

References (63)

1. Barker DJ, Osmond C. Infant mortality, childhood nutrition, and ischaemic heart disease in England and Wales. Lancet 1986; 1: 1077-81.
2. Barker DJP, Osmond C, Winter PD, Margetts B, Simmonds SJ. Weight in infancy and death from ischaemic heart disease. Lancet 1989; 2: 577-80.
3. Hales CN, Barker DJP, Clark PMS et al. Fetal and infant growth and impaired glucose tolerance at age 64. Br Med J 1991; 303, 1019-22.
4. Barker DJ, Hales CN, Fall CH, Osmond C, Phipps K, Clark PM. Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth. Diabetologia 1993; 36: 62-7.
5. Barker DJ, Osmond C, Simmonds SJ, Wield GA. The relation of small head circumference and thinness at birth to death from cardiovascular disease in adult life. Br Med J 1993; 306: 422-6.
6. Osmond C, Barker DJ, Winter PD, Fall CH, Simmonds SJ. Early growth and death from cardiovascular disease in women. Br Med J 1993; 307: 1519-24.
7. Phipps K, Barker DJ, Hales CN, Fall CH, Osmond C, Clark PM. Fetal growth and impaired glucose tolerance in men and women. Diabetologia 1993; 36: 225-8.
8. McCance DR, Pettitt DJ, Hanson RL, Jacobsson LT, Bennett PH, Knowler WC. Glucose, insulin concentrations and obesity in childhood and adolescence as predictors of NIDDM. Diabetologia 1994; 37: 617-23.
9. McCance DR, Pettitt DJ, Hanson RL, Jacobsson LTH, Knowler WC, Bennett PH. Birth weight and non-insulin dependent diabetes: thrifty genotype, thrifty phenotype, or surviving small baby genotype? Br Med J 1994; 308: 942-5.
10. Phillips DI, Barker DJ, Hales CN, Hirst S, Osmond C. Thinness at birth and insulin resistance in adult life. Diabetologia 1994; 37: 150-4.
11. Valdez R, Athens MA, Thompson GH, Bradshaw BS, Stern MP. Birthweight and adult health outcomes in a biethnic population in the USA. Diabetologia 1994; 37: 624-31.
12. Barker DJ, Martyn CN, Osmond C, Wield GA. Abnormal liver growth in utero and death from coronary heart disease. Br Med J 1995; 310: 703-4.
13. Fall CH, Osmond C, Barker DJ et al. Fetal and infant growth and cardiovascular risk factors in women. Br Med J 1995; 310: 428-32.
14. Fall CH, Vijayakumar M, Barker DJ, Osmond C, Duggleby S. Weight in infancy and prevalence of coronary heart disease in adult life. Br Med J 1995; 310: 17-9.
15. Frankel S, Elwood P, Sweetnam P, Yarnell J, Smith GD. Birth-weight, body-mass index in middle age, and incident coronary heart disease. Lancet 1996; 348: 1478-80.
16. Frankel S, Elwood P, Sweetnam P, Yarnell J, Smith GD. Birth-weight, adult risk factors and incident coronary heart disease: the Caerphilly Study. Public Health. 1996; 110: 139-43.
17. Lithell HO, McKeigue PM, Berglund L, Mohsen R, Lithell UB, Leon DA. Relation of size at birth to non-insulin dependent diabetes and insulin concentrations in men aged 50-60 years. Br Med J 1996; 312: 406-10.
18. Stein CE, Fall CH, Kumaran K, Osmond C, Cox V, Barker DJ. Fetal growth and coronary heart disease in south India. Lancet 1996; 348: 1269-73.
19. Forsén T, Eriksson JG, Tuomilehto J, Teramo K, Osmond C, Barker DJP. Mother's weight in pregnancy and coronary heart disease in Finnish men. Br Med J 1997; 315: 837-40.
20. Rich-Edwards JW, Stampfer MJ, Manson JE et al. Birth weight and risk of cardiovascular disease in a cohort of women followed up since 1976. Br Med J 1997; 315: 396-400.
21. Leon DA, Lithell HO, Vagero D et al. Reduced fetal growth rate and increased risk of death from ischaemic heart disease: cohort study of 15 000 Swedish men and women born 1915-29. Br Med J 1998; 317: 241-5.
22. McKeigue PM, Lithell HO, Leon DA. Glucose tolerance and resistance to insulin-stimulated glucose uptake in men aged 70 years in relation to size at birth. Diabetologia 1998; 41: 1133-8.
23. Ravelli AC, van der Meulen JH, Michels RP et al. Glucose tolerance in adults after prenatal exposure to famine. Lancet 1998; 351: 173-7.
24. Eriksson JG, Forsen T, Tuomilehto J, Winter PD, Osmond C, Barker DJP. Catch-up growth in childhood and death from coronary heart disease: longitudinal study. Br Med J 1999; 318, 427-31.
25. Forsen T, Eriksson JG, Tuomilehto J, Osmond C, Barker DJ. Growth in utero and during childhood among women who develop coronary heart disease: longitudinal study. Br Med J 1999; 319: 1403-7.
26. Forsen T, Eriksson J, Tuomilehto J, Reunanen A, Osmond C, Barker D. The fetal and childhood growth of persons who develop type 2 diabetes. Ann Intern Med 2000; 133: 176-82.
27. Roseboom TJ, van der Meulen JH, Osmond C et al. Coronary heart disease after prenatal exposure to the Dutch famine, 1944-45. Heart 2000; 84: 595-8.
28. Eriksson JG, Forsen T, Tuomilehto J, Osmond C, Barker DJP. Early growth and coronary heart disease in later life: longitudinal study. Br Med J 2001; 322: 949-53.
29. Jensen CB, Storgaard H, Dela F, Holst JJ, Madsbad S, Vaag AA. Early differential defects of insulin secretion and action in 19-year-old caucasian men who had low birth weight. Diabetes 2002; 51: 1271-80.
30. Eriksson J, Forsen T, Osmond C, Barker D. Pathways of infant and childhood growth that lead to type 2 diabetes. Diabetes Care 2003; 26: 3006-10.
31. Eriksson JG, Forsen T, Tuomilehto J, Osmond C, Barker DJP. Early adiposity rebound in childhood and risk of type 2 diabetes in adult life. Diabetologia 2003; 46: 322-9.
32. Wei JN, Sung FC, Li CY et al. Low birth weight and high birth weight infants are both at an increased risk to have type 2 diabetes among schoolchildren in Taiwan. Diabetes Care 2003; 26: 343-8.
33. Barghava SK, Sachdev HS, Fall CHD et al. Relation of serial changes in childhood body-mass index to impaired glucose tolerance in young adulthood. N Engl J Med 2004; 350: 865-75.
34. Forsen T, Osmond C, Eriksson JG, Barker DJ. Growth of girls who later develop coronary heart disease. Heart 2004; 90: 20-4.
35. Yajnik CS. Early life origins of insulin resistance and type 2 diabetes in India and other Asian countries. J Nutr 2004; 134: 205-10.
36. Barker DJP, Osmond C, Forsen TJ, Kajantie E, Eriksson JG. Trajectories of growth among children who later have coronary event. N Engl J Med 2005; 353: 1802-9.
37. Ozanne SE, Jensen CB, Tingey KJ, Storgaard H, Madsbad S, Vaag AA. Low birthweight is associated with specific changes in muscle insulin-signalling protein expression. Diabetologia 2005; 48: 547-52.
38. Rich-Edwards JW, Kleinman K, Michels KB et al. Longitudinal study of birth weight and adult body mass index in predicting risk of coronary heart disease and stroke in women. Br Med J. 2005; 330: 1115-20.
39. Eriksson JG, Osmond C, Kajantie E, Forsén TJ, Barker DJP. Patterns of growth among children who later develop type 2 diabetes or its risk factors. Diabetologia 2006; 49: 2853-8.
40. Lawlor DA, Davey Smith G, Clark H, Leon DA. The associations of birthweight, gestational age and childhood BMI with type 2 diabetes: findings from the Aberdeen Children of the 1950s cohort. Diabetologia 2006; 49: 2614-7.
41. Painter RC, de Rooij SR, Bossuyt PM et al. Early onset of coronary artery disease after prenatal exposure to the Dutch famine. Am J Clin Nutr 2006; 84: 322-7.
42. de Rooij SR, Painter RC, Roseboom TJ et al. Glucose tolerance at age 58 and the decline of glucose tolerance in comparison with age 50 in people prenatally exposed to the Dutch famine. Diabetologia 2006; 49: 637-43.
43. Roseboom T, de Rooij S, Painter R. The Dutch famine and its long-term consequences for adult health. Early Hum Dev. 2006; 82: 485-91.
44. Fall CHD, Barker DJP, Osmond C, Winter PD, Clark PMS, Hales CN. Relation of infant feeding to adult serum cholesterol concentration and death from ischaemic heart disease. Br Med J 1991; 304: 801-5.
45. Barker DJP, Martyn CN, Osmond C, Hales CN, Fall CHD. Growth in utero and serum cholesterol concentrations in adult life. Br Med J 1993; 307: 1524-7.
46. Singhal A, Cole TJ, Fewtrell M, Deanfield J, Lucas A. Is slower early growth beneficial for long-term cardiovascular health? Circulation 2004; 109: 1108-13.
47. Singhal A, Lucas A. Early origins of cardiovascular disease: is there a unifying hypothesis? Lancet 2004; 363: 1642-5.
48. Eriksson J, Forsen T, Osmond C, Barker D. Obesity from cradle to grave. Int J Obes Relat Metab Disord 2003; 27, 722-7.
49. Rolland-Cachera MF, Deheeger M, Bellisle F et al. Adiposity rebound in children: a simple indicator for predicting obesity. Am J Clin Nutr 1984; 39: 129-35.
50. Hattersley AT, Tooke JE. The fetal insulin hypothesis: an alternative explanation of the association of low birth-weight with diabetes and vascular disease. Lancet 1999; 353: 1789-92
51. Ong KKL, Phillips DI, Fall C et al. The insulin gene VNTR, type 2 diabetes and birth weight. Nat Genet 1999; 21: 262-3.
52. Vaessen N, Janssen JA, Heutink P et al. Associations between genetic variation in the gene for insulin-like growth factor-I and low birth weight. Lancet 2002; 359: 1036-7.
53. Debril MB, Renaud JP, Fajas L, Auwerx J. The pleiotropic functions of peroxisome proliferator-activated receptor g. J Mol Med 2001; 79: 30-47.
54. Stumvoll M, Häring H. The peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism. Diabetes 2002; 51: 2341-7.
55. Tonjes A, Scholz M, Loeffler M, Stumvoll M. Association of Pro12Ala polymorphism in peroxisome proliferator-activated receptor γ with pre-diabetic phenotypes: meta-analysis of 57 studies on nondiabetic individuals. Diabetes Care 2006; 29: 2489-97.
56. Scaglioni S, Verduci E, Salvioni M et al. PPAR-gamma2 Pro12Ala variant, insulin resistance and plasma long-chain polyunsaturated fatty acids in childhood obesity. Pediatr Res 2006; 60: 485-9.
57. Soriguer F, Morcillo S, Cardona F et al. Pro12Ala polymorphism of the PPARG2 gene is associated with type 2 diabetes mellitus and peripheral insulin sensitivity in a population with a high intake of oleic acid. J Nutr 2006; 136: 2325-30.
58. Laakso M. How good a marker is insulin level for insulin resistance? Am J Epidemiol 1993; 137: 959-65.
59. Eriksson JG, Lindi V, Uusitupa M. The effects of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 gene on insulin sensitivity and insulin metabolism interact with size at birth. Diabetes 2002; 51: 2321-4.
60. Eriksson JG, Osmond C, Lindi V et al. Interactions between peroxisome proliferator-activated receptor gene polymorphism and birth length influence risk for type 2 diabetes. Diabetes Care 2003; 26: 2476-7.
61. Eriksson J, Lindi V, Uusitupa M et al. The effects of the Pro12Ala polymorphism of the PPARgamma-2 gene on lipid metabolism interact with body size at birth. Clin Genet 2003; 64: 366-70.
62. Gu HF, Almgren P, Lindholm E et al. Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis. Diabetes 2000; 49: 1601-3.
63. Kubaszek A, Markkanen A, Eriksson JG et al. The association of the K121Q polymorphism of the plasma cell glycoprotein-1gene with type 2 diabetes and hypertension depends on size at birth. J Clin Endocrinol Metab 2004; 89: 2044-7.