Synthesis of a selective estrogen receptor β-modulator via asymmetric phase-transfer catalysis

Tetrahedron

Volumn 63, Issue 21, 2007, Pages 4459-4463

  Huffman, Mark A ^a   Rosen, Jonathan D ^a   Farr, Roger N ^a   Lynch, Joseph E ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Asymmetric catalysis; Bromination; Chlorination; Phase transfer catalysis

Indexed keywords

2 FLUOROANISOLE; 4 BROMO 9A BUTYL 8 CHLORO 6 FLUORO 7 HYDROXY 1,2,9,9A TETRAHYDROFLUOREN 3 ONE; ANISOLE DERIVATIVE; BROMINE; FLUORENONE DERIVATIVE; FLUORINE DERIVATIVE; IMIDAZOLE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; ASYMMETRIC CATALYSIS; ASYMMETRIC SYNTHESIS; BROMINATION; CHEMICAL STRUCTURE; CHLORINATION; CRYSTALLIZATION; DRUG SYNTHESIS; PHASE TRANSITION; PRIORITY JOURNAL; RACEMIZATION;

EID: 34247133062     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2007.03.074     Document Type: Article

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