Enhancement of fludioxonil fungicidal activity by disrupting cellular glutathione homeostasis with 2,5-dihydroxybenzoic acid

FEMS Microbiology Letters

Volumn 270, Issue 2, 2007, Pages 284-290

  Kim, Jong H ^a   Campbell, Bruce C ^a   Mahoney, Noreen ^a   Chan, Kathleen L ^a   Molyneux, Russell J ^a   May, Gregory S ^b  

^a WESTERN REGIONAL RESEARCH CENTER   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

2,5 dihydroxybenzoic acid; Antioxidative stress system; Aspergillus; Fludioxonil; Saccharomyces cerevisiae

Indexed keywords

ANTIFUNGAL AGENT; FLUDIOXONIL; GENTISIC ACID; GLUTATHIONE; GLUTATHIONE DISULFIDE; MITOGEN ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ARTICLE; CELL LEVEL; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; FUNGICIDAL ACTIVITY; HOMEOSTASIS; NONHUMAN; OSMOTIC STRESS; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; REDUCTION;

ANTIBIOTICS, ANTIFUNGAL; ASPERGILLUS FLAVUS; ASPERGILLUS FUMIGATUS; ASPIRIN; DIOXOLES; DRUG SYNERGISM; GENTISATES; GLUTATHIONE; HOMEOSTASIS; MAP KINASE SIGNALING SYSTEM; MICROBIAL SENSITIVITY TESTS; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION; PYRROLES; STRUCTURE-ACTIVITY RELATIONSHIP;

ASPERGILLUS; SACCHAROMYCES CEREVISIAE;

EID: 34247131370     PISSN: 03781097     EISSN: 15746968     Source Type: Journal    
DOI: 10.1111/j.1574-6968.2007.00682.x     Document Type: Article

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