TNF-α upregulates VCAM-1 and NF-κB in fibroblasts from nasal polyps

Auris Nasus Larynx

Volumn 34, Issue 2, 2007, Pages 177-183

  Ohori, Junichiro ^a   Ushikai, Masato ^a   Sun, Dong ^a   Nishimoto, Kengo ^a   Sagara, Yukari ^a   Fukuiwa, Tatsuya ^a   Matsune, Shoji ^a   Kurono, Yuichi ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

Adhesion molecule; Eosinophil infiltration; Nasal polyp; Signal pathway

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; CELL ISOLATION; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST; FLOW CYTOMETRY; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; MOLECULAR BIOLOGY; NOSE POLYP; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

CELLS, CULTURED; CYSTEINE PROTEINASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBROBLASTS; FLOW CYTOMETRY; HUMANS; LEUPEPTINS; NASAL POLYPS; NF-KAPPA B; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION; VASCULAR CELL ADHESION MOLECULE-1;

EID: 34247125318     PISSN: 03858146     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.anl.2006.05.008     Document Type: Article

References (30)

1. Kawabori S., Denburg J.A., Schwartz L.B., Irani A.A., Wong D., Jordana M., et al. Histochemical and immunohistochemical characteristics of mast cells in nasal polyps. Am J Respir Cell Mol Biol 6 (1992) 37-43
2. Stoop A.E., van der Heijden H.A., Biewenga J., and van der Baan S. Eosinophils in nasal polyps and nasal mucosa: an immunohistochemical study. J Allergy Clin Immunol 91 (1993) 616-622
3. Pawankar R. Nasal polyposis: an update: editorial review. Curr Opin Allergy Clin Immunol. 3 (2003) 1-6
4. Kramer M.F., and Rasp G. Nasal polyposis: eosinophils and interleukin-5. Allergy 55 (1999) 669-680
5. Springer T.A. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76 (1994) 301
6. Iademarco M.F., McQuillan J.J., Rosen G.D., and Dean D.C. Characterization of the promoter for vascular cell adhesion molecule-1 (VCAM-1). J Biol Chem 267 (1992) 16323
7. Haraldsen G., Kvale D., Lien B., Farstad I.N., and Brandtzaeg P. Cytokine-regulated expression of E-selectin, intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1) in human microvascular endothelial cells. J Immunol 156 (1996) 2558-2565
8. Sabatini F., Silvestri M., Sale R., Scarso L., Defilippi A.C., Risso F.M., et al. Fibroblast-eosinophil interaction: modulation of adhesion molecules expression and chemokine release by human fetal lung fibroblasts in response to IL-4 and TNF-α. Immunol Lett 84 (2002) 173-178
9. Li P., Sanz I., O'Keefe R.J., and Schwarz E.M. NF-kappa B regulates VCAM-1 expression on fibroblast-like synoviocytes. J Immunol 164 (2000) 5990-5997
10. Takafuji S., Shoji S., Ito K., Yamamoto K., and Nakagawa T. Eosinophil degranulation in the presence of lung fibroblasts. Int Arch Allergy Immunol 117 Suppl. 1 (1998) 52-54
11. Silvestri M., Sabatini F., Scarso L., Cordone A., Dasic G., and Rossi G.A. Fluticasone propionate downregulates nasal fibroblast functions involved in airway inflammation and remodeling. Int Arch Allergy Immunol 128 (2002) 51-58
12. Nonaka M., Pawankar R., Saji F., and Yagi T. Distinct expression of RANTES and GM-CSF by lipopolysaccharide in human nasal fibroblasts but not in other airway fibroblasts. Int Arch Allergy Immunol 119 (1999) 314-321
13. Miyanohara T., Ushikai M., Matsune S., Ueno K., Katahira S., and Kurono Y. Effects of clarithromycin on cultured human nasal epithelial cells and fibroblasts. Laryngoscope 110 (2000) 126-131
14. Fiedler M.A., Wernke-Dollries K., and Stark J.M. Inhibition of TNF-alpha-induced NF-kappaB activation and IL-8 release in A549 cells with the proteasome inhibitor MG-132. Am J Respir Cell Mol Biol 19 (1998) 259-268
15. Gao J.X., and Issekutz A.C. Expression of VCAM-1 and VLA-4 dependent T-lymphocyte adhesion to dermal fibroblasts stimulated with proinflammatory cytokines. Immunology 89 (1996) 375-383
16. Bradding P., Mediwale R., Feather I.H., Madden J., Church M.K., Holgate S.T., et al. TNF-alpha is localized to nasal mucosal mast cells and is released in acute allergic rhinitis. Clin Exp Allergy 25 (1995) 406-415
17. Finotto S., Ohno I., Marshall J.S., Gauldie J., Denburg J.A., Dolovich J., et al. TNF-alpha production by eosinophils in upper airways inflammation (nasal polyposis). J Immunol 153 (1994) 2278-2289
18. Bolard F., Gosset P., Lamblin C., Bergoin C., Tonnel A.B., and Wallaert B. Cell and cytokine profiles in nasal secretions from patients with nasal polyposis: effects of topical steroids and surgical treatment. Allergy 56 (2001) 333-338
19. Jahnsen F.L., Haraldsen G., Aanesen J.P., Haye R., and Brandtzaeg P. Eosinophil infiltration is related to increased expression of vascular cell adhesion molecule-1 in nasal polyps. Am J Respir Cell Mol Biol 12 (1995) 624-632
20. Littler A.J., Buckley C.D., Wordsworth P., Collins I., Martinson J., and Simmons D.L. A distinct profile of six soluble adhesion molecules (ICAM-1, ICAM-3, VCAM-1, E-selectin L-selectin and P-selectin) in rheumatoid arthritis. Br J Rheumatol 36 (1997) 164-169
21. Velikova G., Banks R.E., Gearing A., Hemingway I., Forbes M.A., Preston S.R., et al. Circulating soluble adhesion molecules E-cadherin, E-selectin, intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) in patients with gastric cancer. Br J Cancer 76 (1997) 1398-1404
22. Nagata M., Sedgwick J.B., Vrtis R., and Busse W.W. Endothelial cells upregulate eosinophil superoxide generation via VCAM-1 expression. Clin Exp Allergy 29 (1999) 550-561
23. Nakao S., Kuwano T., Ishibashi T., Kuwano M., and Ono M. Synergistic effect of TNF-alpha in soluble VCAM-1-induced angiogenesis through alpha 4 integrins. J Immunol 170 (2003) 5704-5711
24. Gallois C., Habib A., Tao J., Moulin S., Maclouf J., Mallat A., et al. Role of NF-kappaB in the antiproliferative effect of endothelin-1 and tumor necrosis factor-alpha in human hepatic stellate cells. Involvement of cyclooxygenase-2. J Biol Chem 273 (1998) 23183-23190
25. McCarty J.M., Yee E.K., Deisher T.A., Harlan J.M., and Kaushansky K. Interleukin-4 induces endothelial vascular cell adhesion molecule-1 (VCAM-1) by an NF-kappa B-independent mechanism. FEBS Lett 372 (1995) 194-198
26. Baldwin Jr. A.S. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu Rev Immunol 14 (1996) 649-683
27. Sakai T., Kambe F., Mitsuyama H., Ishiguro N., Kurokouchi K., Takigawa M., et al. Tumor necrosis factor alpha induces expression of genes for matrix degradation in human chondrocyte-like HCS-2/8 cells through activation of NF-kappa B: abrogation of the tumor necrosis factor alpha effect by proteasome inhibitors. J Bone Miner Res 16 (2001) 1272-1280
28. Thompson J.E., Phillips R.J., Erdjument-Bromage H., Tempst P., and Ghosh S. I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B. Cell 80 (1995) 573-582
29. Takaki M., Ushikai M., Deguchi K., Nishimoto K., Matsune S., and Kurono Y. The role of nuclear factor-kappa B in interleukin-8 expression by human adenoidal fibroblasts. Laryngoscope 113 (2003) 1378-1385
30. Rihoux J.P., Michel L., Arnold R., and Konig W. Hypothetical mechanisms of action of an H1-antihistamine in asthma. Int Arch Allergy Immunol 118 (1999) 380-383