Bone mineral status in children with congenital adrenal hyperplasia

Journal of Pediatric Endocrinology and Metabolism

Volumn 20, Issue 2, 2007, Pages 227-235

  Fleischman, Amy ^a   Ringelheim, Julie ^a   Feldman, Henry A ^a   Gordon, Catherine M ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Bone age; Bone mineral density; Congenital adrenal hyperplasia (CAH); Glucocorticoids; Lean body mass

Indexed keywords

ALDOSTERONE; ANDROGEN; DEXAMETHASONE; GLUCOCORTICOID; HYDROCORTISONE; MINERALOCORTICOID; PREDNISONE; STEROID 21 MONOOXYGENASE;

ADOLESCENT; AGE; ALDOSTERONE RELEASE; ANDROGEN BLOOD LEVEL; ARTICLE; BODY FAT; BONE AGE; BONE DENSITY; BONE GROWTH; BONE MINERAL; CLINICAL ARTICLE; CONGENITAL ADRENAL HYPERPLASIA; CONTROLLED STUDY; CORRELATION ANALYSIS; ETHNICITY; FEMALE; GENDER; HUMAN; HYDROCORTISONE RELEASE; LEAN BODY WEIGHT; LONG TERM CARE; MALE; SCHOOL CHILD; STEROID 21 MONOOXYGENASE DEFICIENCY; ADULT; BODY COMPOSITION; BONE; CHILD; CROSS-SECTIONAL STUDY; DRUG EFFECT; EVALUATION; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; REGRESSION ANALYSIS;

ADOLESCENT; ADRENAL HYPERPLASIA, CONGENITAL; ADULT; ANDROGENS; BODY COMPOSITION; BONE AND BONES; BONE DENSITY; CHILD; CROSS-SECTIONAL STUDIES; FEMALE; GLUCOCORTICOIDS; HUMANS; MALE; REGRESSION ANALYSIS; STEROID 21-HYDROXYLASE;

EID: 34247106732     PISSN: 0334018X     EISSN: None     Source Type: Journal    
DOI: 10.1515/JPEM.2007.20.2.227     Document Type: Article

References (34)

1. Speiser PW, White PC. Congenital adrenal hyperplasia. N Engl J Med 2003; 349: 776-788.
2. Migeon CJ, Wisniewski AB. Congenital adrenal hyperplasia owing to 21-hydroxylase deficiency. Growth, development, and therapeutic considerations. Endocrinol Metab Clin North Am 2001; 30: 193-206.
3. Doyle F, Brown J, Lachance C. Relation between bone mass and muscle weight. Lancet 1970; i: 391-393.
4. Frost HM. Muscle, bone, and the Utah paradigm: a 1999 overview. Med Sci Sports Exerc 2000; 32: 911-917.
5. Rauch F, Schoenau E. The developing bone: slave or master of its cells and molecules? Pediatr Res 2001; 50: 309-314.
6. Burr DB. Muscle strength, bone mass, and age-related bone loss. J Bone Miner Res 1997; 12: 1547-1551.
7. Rauch F, Bailey DA, Baxter-Jones A, Mirwald R, Faulkner R. The 'muscle-bone unit' during the pubertal growth spurt. Bone 2004; 34: 771-775.
8. Marshall WA, Tanner JM. Growth and physiological development during adolescence. Annu Rev Med 1968; 19: 283-300.
9. Leonard MB, Shults J, Elliott DM, Stallings VA, Zemel BS. Interpretation of whole body dual energy X-ray absorptiometry measures in children: comparison with peripheral quantitative computed tomography. Bone 2004; 34: 1044-1052.
10. Zemel BS. Reference data for the whole body, lumbar spine and proximal femur for American children relative to age, gender and body size. J Bone Miner Res 2004; 1: S231.
11. Kelly T. Bone mineral density reference database for American men and women. J Bone Miner Res 1990; S249.
12. Katzman DK, Bachrach LK, Carter DR, Marcus R. Clinical and anthropometric correlates of bone mineral acquisition in healthy adolescent girls. J Clin Endocrinol Metab 1991; 73: 1332-1339.
13. Mora S, Prinster C, Proverbio MC, Bellini A, de Poli SC, Weber G, Abbiati G, Chiumello G. Urinary markers of bone turnover in healthy children and adolescents: age-related changes and effect of puberty. Calcif Tissue Int 1998; 63: 369-374.
14. Rehman Q, Lane NE. Effect of glucocorticoids on bone density. Med Pediatr Oncol 2003; 41: 212-216.
15. Jaaskelainen J, Voutilainen R. Bone mineral density in relation to glucocorticoid substitution therapy in adult patients with 21-hydroxylase deficiency. Clin Endocrinol (Oxf) 1996; 45: 707-713.
16. Hagenfeldt K, Martin Ritzen E, Ringertz H, Helleday J, Carlstrom K. Bone mass and body composition of adult women with congenital virilizing 21-hydroxylase deficiency after glucocorticoid treatment since infancy. Eur J Endocrinol 2000; 143: 667-671.
17. Guo CY, Weetman AP, Eastell R. Bone turnover and bone mineral density in patients with congenital adrenal hyperplasia. Clin Endocrinol (Oxf) 1996; 45: 535-541.
18. Stikkelbroeck NM, Oyen WJ, van der Wilt GJ, Hermus AR, Otten BJ. Normal bone mineral density and lean body mass, but increased fat mass, in young adult patients with congenital adrenal hyperplasia. J Clin Endocrinol Metab 2003; 88: 1036-1042.
19. Girgis R, Winter JS. The effects of glucocorticoid replacement therapy on growth, bone mineral density, and bone turnover markers in children with congenital adrenal hyperplasia. J Clin Endocrinol Metab 1997; 82: 3926-3929.
20. Mora S, Saggion F, Russo G, Weber G, Bellini A, Prinster C, Chiumello G. Bone density in young patients with congenital adrenal hyperplasia. Bone 1996; 18: 337-340.
21. Cameron FJ, Kaymakci B, Byrt EA, Ebeling PR, Warne GL, Wark JD. Bone mineral density and body composition in congenital adrenal hyperplasia. J Clin Endocrinol Metab 1995; 80: 2238-2243.
22. Gussinye M, Carrascosa A, Potau N, Enrubia M, Vicens-Calvet E, Ibanez L, Yeste D. Bone mineral density in prepubertal and in adolescent and young adult patients with the salt-wasting form of congenital adrenal hyperplasia. Pediatrics 1997; 100: 671-674.
23. Paganini C, Radetti G, Livieri C, Braga V, Migliavacca D, Adami S. Height, bone mineral density and bone markers in congenital adrenal hyperplasia. Horm Res 2000; 54: 164-168.
24. de Almeida Freire PO, de Lemos-Marini SH, Maciel-Guerra AT, Morcillo AM, Matias Baptista MT, de Mello MP, Guerra G Jr. Classical congenital adrenal hyperplasia due to 21-hydroxylase deficiency: a cross-sectional study of factors involved in bone mineral density. J Bone Miner Metab 2003; 21: 396-401.
25. Leonard MB, Feldman HI, Shults J, Zemel BS, Foster BJ, Stallings VA. Long-term, high-dose glucocorticoids and bone mineral content in childhood glucocorticoid-sensitive nephrotic syndrome. N Engl J Med 2004; 351: 868-875.
26. Bechtold S, Ripperger P, Dalla Pozza R, Schmidt H, Hafner R, Schwarz HP. Musculoskeletal and functional muscle-bone analysis in children with rheumatic disease using peripheral quantitative computed tomography. Osteoporos Int 2005; 16: 757-763.
27. Falcini F, Bindi G, Simonini G, Stagi S, Galluzzi F, Masi L, Cimaz R. Bone status evaluation with calcaneal ultrasound in children with chronic rheumatic diseases. A one year follow-up study. J Rheumatol 2003; 30: 179-184.
28. Cetin A, Celiker R, Dincer F, Ariyurek M. Bone mineral density in children with juvenile chronic arthritis. Clin Rheumatol 1998; 17: 551-553.
29. Mulder JE, Bilezikian JP. Bone density in survivors of childhood cancer. J Clin Densitom 2004; 7: 432-442.
30. Atkinson SA, Halton JM, Bradley C, Wu B, Barr RD. Bone and mineral abnormalities in childhood acute lymphoblastic leukemia: influence of disease, drugs and nutrition. Int J Cancer Suppl 1998; 11: 35-39.
31. Lisa L, Neradilova M, Tomasova N, Soutorova M, Zimak J. Osteocalcin in congenital adrenal hyperplasia. Bone 1995; 16: 57-59.
32. Hargitai G, Hosszu E, Halasz Z, Solyom J. Serum osteocalcin and insulin-like growth factor I levels in children with congenital adrenal hyperplasia. Horm Res 1999; 52: 131-139.
33. Wang MC, Bachrach LK, Van Loan M, Hudes M, Flegal KM, Crawford PB. The relative contributions of lean tissue mass and fat mass to bone density in young women. Bone 2005; 37: 474-481.
34. Petit MA, Beck TJ, Shults J, Zemel BS, Foster BJ, Leonard MB. Proximal femur bone geometry is appropriately adapted to lean mass in overweight children and adolescents. Bone 2005; 36: 568-576.