Mechanical stress activates platelets at a subhemolysis level: An in vitro study

Artificial Organs

Volumn 31, Issue 4, 2007, Pages 316-323

  Bakir, Ihsan ^a,e,f   Hoylaerts, Marc F ^b   Kink, Thomas ^c   Foubert, Luc ^d   Luyten, Peter ^a   Van Kerckhoven, Soetkin ^b   Leunens, Veerle ^a   Bollen, Hilde ^a   Reul, Helmut ^c   Meyns, Bart ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c RWTH AACHEN UNIVERSITY   (Germany)

^d OLV HOSPITAL   (Belgium)

^e DR SIYAMI ERSEK THORACIC AND CARDIOVASCULAR SURGERY TRAINING AND RESEARCH HOSPITAL   (Turkey)

^f NONE   (Turkey)

Author keywords

Free hemoglobin; Hemoresistometer; Platelet count; Shear stress; Sheep blood

Indexed keywords

ANIMALS; HEMOGLOBIN; PLATELETS; SHEAR DEFORMATION; TESTING;

FREE HEMOGLOBIN; HAEMOGLOBINS; HAEMOLYSIS; HEMORESISTOMETERS; IN-VITRO; MECHANICAL STRESS; PLATELET COUNT; SHEAR-RATE; SHEEP BLOOD; VITRO STUDIES;

SHEAR STRESS;

HEMOGLOBIN;

ANALYTICAL EQUIPMENT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; FEASIBILITY STUDY; HEMOLYSIS; IN VITRO STUDY; MECHANICAL STRESS; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SHEAR STRESS; SHEEP; STATISTICAL SIGNIFICANCE; THROMBOCYTE ACTIVATION; THROMBOCYTE COUNT;

ANIMALIA; OVIS ARIES;

EID: 34247092865     PISSN: 0160564X     EISSN: 15251594     Source Type: Journal    
DOI: 10.1111/j.1525-1594.2007.00381.x     Document Type: Article

References (24)

1. Klaus S, Körfer S, Mottaghy K, Reul H, Glasmacher B. In vitro blood damage by high shear flow: human versus porcine blood. Int J Artif Organs 2002;25:306-12.
2. Gu L, Smith WA, Chatzimavroudis GP. Mechanical fragility calibration of red blood cells. ASAIO J 2005;51:194-201.
3. Goodman SL. Sheep, pig, and human platelet-material interactions with model cardiovascular biomaterials. J Biomed Mater Res 1999;45:240-50.
4. Indeglia RA, Shea MA, Varco RL, Bernstein EF. Mechanical and biologic considerations in erythrocyte damage. Surgery 1967;62:47-55.
5. Weiss HJ, Turitto VT, Baumgartner HR. Effect of shear rate on platelet interaction with subendothelium in citrated and native blood. I. Shear rate-dependent decrease of adhesion in von Willebrand's disease and the Bernard-Soulier syndrome. J Lab Clin Med 1978;92:750-64.
6. Baumgartner HR, Turitto VT, Weiss HJ. Effect of shear rate on platelet interaction with subendothelium in citrated and native blood. II. Relationships among platelet adhesion, thrombus dimensions, and fibrin formation. J Lab Clin Med 1980;95:208-21.
7. Apel J, Paul R, Klaus S, Siess T, Reul H. Assessment of hemolysis-related quantities in a microaxial blood pump by computational fluid dynamics. Artif Organs 2001;25:341-7.
8. Paul R, Apel J, Klaus S, Schügner F, Schwindke P, Reul H. Shear stress-related blood damage in laminar Couette flow. Artif Organs 2003;27:517-29.
9. Boothe JG, Saponja JA, Parmenter DL. Molecular farming in plants: oilseeds as vehicles for the production of pharmaceutical proteins. Drug Develop Res 1997;42:172-81.
10. Allain JP, Cooper HA, Wagner RH, Brinkhous KM. Platelets fixed with paraformaldehyde: a new reagent for assay of von Willebrand factor and platelet aggregating factor. J Lab Clin Med 1975;85:318-28.
11. Fuzaylov SY, Serebruany VL. Amount of paraformaldehyde for sample fixation markedly affects the quality of platelet assessment by flow cytometry: experience from two clinical trials. Thromb Res 2000;99:643-4.
12. Linneweber J, Chow TW, Kawamura M, Moake JL, Nose Y. In vitro comparison of blood pump induced platelet microaggregates between a centrifugal and roller pump during cardiopulmonary bypass. Int J Artif Organs 2002;25:549-55.
13. Miyazaki Y, Nomura S, Miyake T, et al. High shear stress can initiate both platelet aggregation and shedding of procoagulant containing microparticles. Blood 1996;88:3456-64.
14. Ohta Y, Okamoto H, Kanno M, Okuda T. Atomic force microscopic observation of mechanically traumatized erythrocytes. Artif Organs 2002;26:10-7.
15. Reimers RC, Sutera SP, Joist H. Potentiation by red blood cells of shear-induced platelet aggregation: relative importance of chemical and physical mechanisms. Blood 1984;64:1200-6.
16. Mohara J, Kawahito K, Misawa Y, Fuse K. Evaluation of platelet damage in two different centrifugal pumps based on measurements of a-granule packing proteins. Artif Organs 1998;22:371-4.
17. Brown CH III, Leverett LB, Levis CW, Alfrey CP, Hellums JD. Morphological, biochemical and functional changes in human platelets subjected to shear stress. J Lab Clin Med 1975;86:462-71.
18. Andersen KS, Nygreen EL, Grong K, Leirvaag B, Holmsen H. Comparison of the centrifugal and roller pump in elective coronary artery bypass surgery - a prospective, randomized study with special emphasis upon platelet activation. Scand Cardiovasc J 2003;37:356-62.
19. Sakariassen KS, Hanson SR, Cadroy Y. Methods and models to evaluate shear-dependent and surface reactivity-dependent antithrombotic efficacy. Thromb Res 2001;104:149-74.
20. Gaarder A, Jonsen J, Laland S, Hellem A, Owren PA. Adenosine diphosphate in red cells as a factor in the adhesiveness of human blood platelets. Nature 1961;192:531-2.
21. Born GV. Aggregation of blood platelets by adenosine diphosphate and its reversal. Nature 1962;194:927-9.
22. Alkhamis TM, Beissinger RL, Chediak JR. Artificial surface effect on red blood cells and platelets in laminar shear flow. Blood 1990;75:1568-75.
23. Born GV, Bergquist D, Arfors KE. Evidence for inhibition of platelet activation in blood by a drug effect on erythrocytes. Nature 1976;259:233-5.
24. Aarts PA, Bolhuis PA, Sakariassen KS, Heethaar RM, Sixma JJ. Red blood cell size is important for adherence of blood platelets to artery subendothelium. Blood 1983;62:214-7.