Asymmetric total synthesis and formal total synthesis of the antitumor sesquiterpenoid (+)-eremantholide A

Organic Letters

Volumn 9, Issue 7, 2007, Pages 1267-1270

  Yi, Li ^a   Hale, Karl J ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; EREMANTHOLIDE A; SESQUITERPENE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; CYCLIZATION; DRUG EFFECT; HUMAN; OXIDATION REDUCTION REACTION; STEREOISOMERISM; SYNTHESIS; TUMOR CELL LINE;

ALKYLATION; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIZATION; HUMANS; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; SESQUITERPENES; STEREOISOMERISM;

EID: 34147190045     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol0700862     Document Type: Article

References (24)

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21. Important Note: Under these conditions, we find that 27 is always formed alongside approximately 14-17% of a lactone migration product that is difficult to remove at this stage; the latter impurity arises from attack of the C(8)-OH in 27 on its own lactone carbonyl.
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