In vivo study of an x-ray fluorescence system to detect bone strontium non-invasively

Physics in Medicine and Biology

Volumn 52, Issue 8, 2007, Pages 2107-2122

  Zamburlini, M ^a   Pejovic Milic A ^a,b   Chettle, D R ^a   Webber, C E ^c   Gyorffy, J ^d  

^a MCMASTER UNIVERSITY   (Canada)

^b RYERSON UNIVERSITY   (Canada)

^c Hamilton Health Sciences ^*  (Canada)

^d Mohawk College of Applied Arts and Technology   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BONE BIOLOGY; BONE STRONTIUM DETECTION; TISSUE ATTENUATION; X-RAY FLUORESCENCE (XRF) SYSTEM;

COMPUTER SIMULATION; FLUORESCENCE SPECTROSCOPY; MONTE CARLO METHODS; NONINVASIVE MEDICAL PROCEDURES; STRONTIUM; TRACE ANALYSIS; ULTRASONIC MEASUREMENT;

BONE;

IODINE 125; STRONTIUM;

ACCURACY; ADULT; AGED; ANKLE; ARTICLE; CONTROLLED STUDY; FEASIBILITY STUDY; FEMALE; HUMAN; HUMAN EXPERIMENT; INDEX FINGER; MALE; MONTE CARLO METHOD; NORMAL HUMAN; PRIORITY JOURNAL; SIMULATION; SOFT TISSUE; ULTRASOUND; X RAY FLUORESCENCE;

ADULT; AGED; BONE AND BONES; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; FEMALE; HUMANS; IODINE RADIOISOTOPES; MALE; MIDDLE AGED; RADIATION DOSAGE; RADIOMETRY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, X-RAY EMISSION; STRONTIUM;

EID: 34147189647     PISSN: 00319155     EISSN: 13616560     Source Type: Journal    
DOI: 10.1088/0031-9155/52/8/005     Document Type: Article

References (38)

1. Barrett-Connor E, Siris E S, Wehren L E, Miller P D, Abbott T A, Berger M L, Santora A C and Sherwood L M 2005 Osteoporosis and fracture risk in women of different ethnic groups J. Bone Miner. Res. 20 185-94
2. Bateman S N, Pejović-Milić A, Stronach I M, McNeill F E and Chettle D R 2000 Performance appraisals of digital spectroscopy systems for the measurement of bone lead Appl. Radiat. Isot. 53 647-50
3. Berger M J, Hubbell J H, Seltzer S M, Chang J, Coursey J S, Sukumar R and Zucker D S 2005 XCOM: Photon Cross Section Database (version 1.3) (Gaithersburg, MD: National Institute of Standards and Technology) (Accessed on September 2006) http://physics.nist.gov/xcom
4. Bevington P R 1969 Data Reduction and Error Analysis for the Physical Sciences (New York: McGraw Hill)
5. Boivin G, Deloffre P, Perrat B, Panczer G, Boudeulle M, Mauras Y, Allain P, Tsouderos Y and Meunier P J 1996 Strontium distribution and interactions with bone mineral in monkey iliac bone after strontium salt (S 12911) administration J. Bone Miner. Res. 11 1302-11
6. Cabrera W E, Schrooten I, De Broe M E and D'Haese P C 1999 Strontium and bone J. Bone Miner. Res. 14 661-8
7. Cohen-Solal M 2002 Strontium overload and toxicity: impact on renal osteodystrophy Nephrol. Dial. Transplant. 17 (Suppl. 2) 30-4
8. Dahl S G, Allain P, Marie P J, Mauras Y, Boivin G, Ammann P, Tsouderos Y, Delmas P D and Christiansen C 2001 Incorporation and distribution of strontium in bone Bone 28 446-53
9. HDI5000 Ultrasound System 2000 Reference Manual 4703-0027-03(USA) pp 6-32
10. Hodges R M, MacDonald N S, Nusbaum R, Stearns R, Ezmirlian F, Spain P and McArthur C 1950 The strontium content of human bones J. Biol. Chem. 185 519-24
11. International Commission on Radiological Protection (ICRP) 1975 Report of the Task Group on Reference Man ICRP Publication 23 (Oxford: Pergamon)
12. International Commission on Radiological Protection (ICRP) 1995 Basic anatomical and physiological data for use in radiological protection: the skeleton ICRP Publication 70 (Oxford: Pergamon)
13. International Commission on Radiological Protection (ICRP) 2002 Basic anatomical and physiological data for use in radiological protection: reference values ICRP Publication 89 (Oxford: Pergamon)
14. Knuuttila M, Lappalainen R, Lammi S, Alhava E and Olkkonen H 1982 Interaction between Li, Ni and Sr content in human cancellous bone Chem. Biol. Interact. 40 77-83
15. LBNL 2007 Isotopes Project Nuclear Data Dissemination Home Page retrieved January 3, 2007 http://ie.lbl.gov/toi.html
16. Marie P J 2006 Strontium ranelate: a dual mode of action rebalancing bone turnover in favour of bone formation Curr. Opin. Rheumatol. 18 S11-5
17. Marie P J, Ammann P, Boivin G and Rey C 2001 Mechanisms of action and therapeutic potential of strontium in bone Calcif. Tissue Int. 69 121-9
18. Meunier P J et al 2004 The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis N. Engl. J. Med. 350 459-68
19. Nelson W R, Hirayama H and Rogers D W O 1985 EGS4 Code System SLAC-265
20. Nielsen S P 2004 The biological role of strontium Bone 35 583-8
21. Nielsen S P, Barenholdt O, Barenholdt-Schioler C, Mauras Y and Allain P 2004 Non invasive measurement of bone strontium J. Clin. Densitometry 7 262-8
22. O'Meara J M, Chettle D R, McNeill F E and Webber C E 1997 The feasibility of measuring bone uranium concentrations in vivo using source excited K x-ray fluorescence Phys. Med. Biol. 42 1109-20
23. Özgür S, Sümer H and Koçoǧlu G 1996 Rickets and soil strontium Arch. Dis. Child. 75 524-6
24. Pecher C 1941 Biological investigations with radioactive calcium and strontium J. Proc. Soc. Exp. Biol. Med. 46 86-91
25. Pejović-Milić A, Brito J A, Gyorffy J and Chettle D R 2002 Ultrasound measurements of overlying soft tissue thickness at four skeletal sites suitable for in vivo x-ray fluorescence Med. Phys. 29 2687-91
26. Pejović-Milić A, Stronach I M, Gyorffy J, Webber C E and Chettle D R 2004 Quantification of bone strontium levels in humans by in vivo x-ray fluorescence Med. Phys. 31 528-38
27. Register J Y et al 2005 Strontium ranelate reduces the risk of nonvertebral fractures in postmenopausal women with osteoporosis: treatment of peripheral osteoporosis (TROPOS) study J. Clin. Endocrinol. Metab. 90 2816-22
28. Sakamoto Y 1993 Proceedings of the third EGS4 User's meeting in Japan KEK Proc. 93-15 pp 77-82
29. Schroeder H A, Tipton I H and Nason A P 1972 Trace metals in man: strontium and barium J. Chron. Dis. 25 491-517
30. Snyder R E and Secord D C 1982 The in situ measurement of strontium content in bone using x-ray-fluorescence analysis Phys. Med. Biol. 27 515-29
31. Somervaille L J, Chettle D R and Scott M C 1985 In vivo measurement of lead in bone using x-ray-fluorescence Phys. Med. Biol. 30 929-43
32. Thurber D L, Kulp J L, Hodges E, Gast P W and Wampler J M 1958 Common strontium content of human skeleton Science 128 256-7
33. Wielopolski L, Vartsky D, Yasumura S and Cohn S H 1983 Application of XRF to measure strontium in human-bone in vivo Adv. X-Ray Anal. 26 415-21
34. X-5 Monte Carlo Team 2003 MCNP-A General Monte Carlo N-Particle Transport Code, Version 5 LA-UR-03_1987 (Los Alamos, NM: Los Alamos National Laboratory)
35. Zaichick V 2004 INAA application in the age dynamics assessment of Ca, Cl, K, Mg, Mn, Na, P and Sr in the cortical bone of human femoral neck J. Radioanal. Nucl. Chem. 259 351-4
36. Zamburlini M, Byun S H, Pejović-Milić A, Prestwich W and Chettle D R 2007 Evaluation of MCNP5 and EGS4 for the simulation of in vivo strontium XRF measurements X-Ray Spectrom. at press
37. 125I in vivo bone strontium x-ray fluorescence measurement J. Radioanal. Nucl. Chem. 269 625-9
38. Zoeger N, Wobrauschek P, Streli C, Pepponi G, Roschger P, Falkenberg G and Osterode W 2005 Distribution of Pb and Zn in slices of human bone by synchrotron μ-XRF X-Ray Spectrom. 34 140-3