Quantification of bone strontium levels in humans by in vivo x-ray fluorescence

Medical Physics

Volumn 31, Issue 3, 2004, Pages 528-538

  Pejovic Milic A ^a   Stronach, I M ^b   Gyorffy, J ^c   Webber, C E ^d   Chettle, D R ^e  

^a RYERSON UNIVERSITY   (Canada)

^b QUEEN ELIZABETH HOSPITAL   (United Kingdom)

^c Mohawk College of Applied Arts and Technology   (Canada)

^d HAMILTON HEALTH SCIENCES   (Canada)

^e MCMASTER UNIVERSITY   (Canada)

Author keywords

Bone strontium; DXA; K x ray fluorescence; Osteoporosis

Indexed keywords

FLUORESCENCE; PATIENT MONITORING; STRONTIUM; X RAY DETECTORS; X RAYS;

DETECTION SYSTEM; HEALTHY SUBJECTS; IN-VIVO MEASUREMENT; MEASUREMENT TIME; OSTEOPOROSIS; SAMPLE POSITION; SYSTEM CALIBRATION; X RAY FLUORESCENCE;

BONE;

CADMIUM 109; STRONTIUM;

ARTICLE; BONE; CALIBRATION; DOSIMETRY; DUAL ENERGY X RAY ABSORPTIOMETRY; ELECTRONICS; GEOMETRY; HUMAN; HUMAN EXPERIMENT; NORMAL HUMAN; OSTEOPOROSIS; PRIORITY JOURNAL; X RAY FLUORESCENCE;

EID: 12144288704     PISSN: 00942405     EISSN: None     Source Type: Journal    
DOI: 10.1118/1.1644931     Document Type: Article

References (39)

1. G. Boivin, P. Deloffre, B. Perrat, G. Panczer, M. Boudeulle, Y. Mauras, Y. Tsouderos, and P. Meunier, "Strontium distribution and interaction with bone mineral in monkey iliac bone after strontium salt (S12911) administration," J. Bone Miner. Res. 11, 1302-1311 (1996).
2. S. G. Dahl, P. Allain, P. J. Marie, Y. Mauras, G. Boivin, P. Ammann, Y. Tsouderos, P. D. Delmas, and C. Christiansen, "Incorporation and distribution of strontium in bone," Sumitomo Electr. Tech. Rev. 28, 446-453 (2001).
3. S. Özgür, H. Sümer, and G. Kocoǧlu, "Rickets and soil strontium," Arch. Dis. Child 75, 524-526 (1996).
4. W. E. Cabrera, I. Schrooten, M. De Broe, and P. D'Haese, "Strontium and bone," J. Bone Miner. Res. 14, 661-668 (1999).
5. P. J. Marie, M. Hott, D. Modrowski, C. de Pollak, J. Guillemain, P. Deloffer, and Y. Tsouderos, "An uncoupling agent containing strontium prevents bone loss by depressing bone resorption and maintaining bone formation in estrogen-deficient rats," J. Bone Miner. Res. 8, 607-615 (1993).
6. J. Y. Reginster, "Miscellaneous and experimental agents," Am. J. Med. Sci. 313, 33-40 (1997).
7. J. Y. Reginster, R. Deroisy, M. Dougados, I. Juspin, J. Colette, and C. Roux, "Prevention of early postmenopausal bone loss by strontium rane-late: The randomized, two-year, double-masked, dose ranging, placebo-controlled PREVOS trial," Osteoporosis Int. 13, 925-931 (2002).
8. S. P. Nielse, D. Slosmna, O. H. Sorensen, B. Basse-Cathalinat, P. De Cassin, C. Roux, and P. J. Meunier, "Influence of strontium bone mineral density and bone mineral content measurements by dual x-ray absorptiometry," J. Clin. Densitom. 2, 371-379 (1999).
9. P. B. Hoffer, W. B. Jones, R. B. Crawford, R. Beck, and A. Gottschalk, "Fluorescent thyroid scanning: a new method of imaging the thyroid," Radiology 90, 342-344 (1968).
10. J. O. Christoffersson and S. Mattsson, "Polarized x-rays in XRF analysis for improved in vivo detestability of cadmium in man," Phys. Med. Biol. 28, 1135-1144 (1983).
11. J. Börjesson, "Studies of cadmium, mercury and lead in man," A Ph.D. thesis, Department of Radiation Physics, University of Göteborg, Göteborg, Sweden, 1996.
12. J. Börjesson, L. Barregård, G. Sällsten, A. Schütz, R. Jonson, M. Alpsten, and S. Mattsson, "In vivo XRF analysis of mercury: relation between concentrations in the kidney and the urine," Phys. Med. Biol. 40, 413-426 (1995).
13. J. M. O'Meara, D. R. Chettle, and C. E. Webber, "The feasibility of measuring bone uranium concentrations in vivo using source excited K x-ray fluorescence," Phys. Med. Biol. 42, 1109-1129 (1997).
14. J. Börjesson and S. Mattsson, "Toxicology: In vivo x-ray fluorescence for the assessment of heavy metal concentrations in man," Appl. Radiat. Isot. 46, 571-576 (1995).
15. S. Shakeshaft and S. C. Lillicrap, "An x-ray fluorescence system for the determination of gold in vivo following chrysotherapy," Br. J. Radiol. 66, 714-717 (1993).
16. R. Jonson, S. Mattsson, and B. Unsgaard, "A method for in vivo analysis of platinum after chemotherapy with cisplatin," Phys. Med. Biol. 33, 847-857 (1988).
17. J. Börjesson, "Measurements of platinum, gold and mercury in vivo: an analysis of the Göteborg XRF in vivo measurement system: improvements, tests, and patient measurements," Fil. Lic. thesis, Department of Radiation Physics, University of Göteborg, Göteborg, Sweden, 1991.
18. L. J. Somervaille, D. R. Chettle, and M. C. Scott, "In vivo measurement of lead in bone using x-ray fluorescence," Phys. Med. Biol. 30, 929-943 (1985).
19. A. C. Todd, P. J. Parsons, S. Carroll, C. Geraghty, F. A. Khan, S. Tang, and E. Moshier, "Measurements of lead in human tibiae. A comparison between K-shell x-ray fluorescence and electrothermal atomic absorption spectrometry," Phys. Med. Biol. 47, 673-687 (2002).
20. C. L. Gordon, D. R. Chettle, and C. E. Webber, "An improved instrument for the in vivo detection of bone lead," Br. J. Ind. Med. 50, 637-641 (1993).
21. D. E. B. Fleming and T. A. Forbes, "Calibration and characterization of a digital x-ray Fluorescence bone lead system," Appl. Radiat. Isot. 55, 527-532 (2001).
22. V. S. Kondrashov and S. J. Rothenberg, "How to calculate lead concentration and concentration uncertainty in XRF in vivo lead analysis," Appl. Radiat. Isot. 55, 799-803 (2001).
23. L. Ahlgren, K. Lidén, S. Mattsson, and S. Tejning, "X-ray fluorescence and analysis of lead in human skeleton in vivo," Scand. J. Work Environ. Health 2, 82-86 (1976).
24. J. O. Christoffersson, A. Schütz, L. Ahlgren, B. Haeger-Aronsen, S. Mattsson, and S. Skerfving, "Lead in finger bone analyzed in vivo in active and retired workers," Am. J. Ind. Med. 6, 447-457 (1984).
25. L. Wielopolski, D. N. Slatkin, D. Vartsky, K. J. Ellis, and S. H. Cohn, "Feasibility study for in vivo measurement of lead in bone using L-x-ray fluorescence," IEEE Trans. Nucl. Sci. 28, 114-116 (1981).
26. L. Wielopolski, J. F. Rosen, D. N. Slatkin, D. Vartsky, K. J. Ellis, and S. H. Cohn, "Feasibility of noninvasive analysis of lead in the human tibia by soft x-ray fluorescence," Med. Phys. 10, 248-251 (1983).
27. L. Wielopolski, J. F. Rosen, D. N. Slatkin, R. Zhang, J. A. Kalef-Ezra, J. C. Rothman, M. Maryanski, and S. T. Jenks, "In vivo measurement of cortical bone lead using polarized x-rays," Med. Phys. 16, 521-528 (1989).
28. S. Mattsson and M. C. Scott, "In vivo elemental analysis using x-ray fluorescence: technique and applications," 2nd International Workshop on XRF and PIXE in the Life Sciences, Capri, 29-30 June 1989.
29. D. R. Chettle, R. Armstrong, A. C. Todd, D. M. Franklin, M. C. Scott, and L. J. Somervaille, "Measurements of trace elements in vivo," in In. Vivo Body Composition Studies, edited by S. Yasumura, J. E. Harrison, K. G. McNeill, A. D. Woodhead, and F. A. Dilmanian (Plenum, New York, 1990), pp. 247-257.
30. L. Wielopolski, "Design consideration for an EDXRF system for in vivo elemental analysis," Adv. X-Ray Anal. 41, 892-897 (1999).
31. G. E. Knoll, Radiation Detection and Measurements (Wiley, New York, 1999).
32. C. M. Lederer and V. S. Shirley, Table of Isotopes, 7th ed. (Wiley, New York, 1978).
33. S. N. Bateman, A. Pejović-Milić, I. M. Stronach, F. E. McNeill, and D. R. Chettle, "Performance appraisals of digital spectroscopy systems for the measurement of bone lead," Appl. Radiat. Isot. 53, 647-650 (2000).
34. M. L. Arnold, F. E. McNeill, I. M. Stronach, A. Waker, A. Pejović-Milić, and D. R. Chettle, "An accelerator based system for in vivo neutron activation analysis measurements of manganese in human hand bones," Med. Phys. 29, 2718-2724 (2002).
35. A. Pejović-Milić, F. E. McNeill, W. V. Prestwich, A. J. Waker, and D. R. Chettle, "Development of an accelerator based determination of aluminum burden in peripheral bone by neutron activation analysis," Appl. Radiat. Isot. 49, 717-719 (1998).
36. A. Pejović-Milić, J. A. Brito, J. Gyorffy, and D. R. Chettle, "Ultrasound measurements of overlying soft tissue thickness at four skeletal sites suitable for in vivo x-ray fluorescence," Med. Phys. 29, 2687-2691 (2002).
37. 109Cd K x-ray fluorescence measurements," Phys. Med. Biol. 44, 2263-2273 (1999).
38. J. M. O'Meara (personal communication).
39. R. Studinski and F. E. McNeill (personal communication).