Mutations in GJB2, GJB6, and mitochondrial DNA are rare in African American and Caribbean Hispanic individuals with hearing impairment

American Journal of Medical Genetics, Part A

Volumn 143, Issue 8, 2007, Pages 830-838

  Samanich, Joy ^a   Lowes, Christina ^a   Burk, Robert ^a   Shanske, Sara ^b   Lu, J ^b   Shanske, Alan ^a   Morrow, Bernice E ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Admixture populations; African American; Connexin 26; Connexin 30; Deafness; Gene frequency; Genetics; GJB2; GJB6; Hearing loss; Hispanic; Mitochondrial mutations; Mutation

Indexed keywords

ADENINE; ARGININE; CYTOSINE; GLUTAMIC ACID; GLUTAMINE; GUANINE; HISTIDINE; ISOLEUCINE; LYSINE; MITOCHONDRIAL DNA; THYMINE; VALINE;

AFRICAN AMERICAN; AMINO ACID SUBSTITUTION; ARTICLE; CARIBBEAN ISLANDS; CONTROLLED STUDY; ETHNIC DIFFERENCE; GENE; GENE FREQUENCY; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GJB2 GENE; GJB6 GENE; HISPANIC; HUMAN; MAJOR CLINICAL STUDY; MITOCHONDRIAL GENETICS; MUTATION RATE; MUTATIONAL ANALYSIS; PERCEPTION DEAFNESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SEQUENCE ANALYSIS;

AFRICAN AMERICANS; CARIBBEAN REGION; CONNEXINS; DNA MUTATIONAL ANALYSIS; DNA, MITOCHONDRIAL; GENE FREQUENCY; HEARING LOSS; HISPANIC AMERICANS; HUMANS; MUTATION;

EID: 34147185848     PISSN: 15524825     EISSN: 15524833     Source Type: Journal    
DOI: 10.1002/ajmg.a.31668     Document Type: Article

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