γ-aminobutyric acid specifically inhibits progression of tubular fibrosis and atrophy in nephrectomized rats

Biological and Pharmaceutical Bulletin

Volumn 30, Issue 4, 2007, Pages 687-691

  Sasaki, Sumiyo ^a   Tohda, Chihiro ^a   Kim, Mujo ^b   Yokozawa, Takako ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b Pharma Foods International Co Ltd   (Japan)

Author keywords

aminobutyric acid; Fibronectin; Renal failure; Transforming growth factor 1; Tubular atrophy; Tubular fibrosis

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR; BACLOFEN; FIBRONECTIN; MUSCIMOL; TRANSFORMING GROWTH FACTOR BETA1; UREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATROPHY; BODY WEIGHT; CONTROLLED STUDY; DISEASE COURSE; DOSE RESPONSE; DRUG INHIBITION; DRUG MECHANISM; FLUID INTAKE; GLOMERULUS; KIDNEY ATROPHY; KIDNEY FIBROSIS; KIDNEY FUNCTION; KIDNEY INJURY; KIDNEY TUBULE; NEPHRECTOMY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; RENAL PROTECTION; TREATMENT DURATION; UREA NITROGEN BLOOD LEVEL;

ANIMALS; ATROPHY; BLOOD UREA NITROGEN; CREATININE; DISEASE PROGRESSION; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBRONECTINS; FIBROSIS; GAMMA-AMINOBUTYRIC ACID; KIDNEY DISEASES; KIDNEY TUBULES; MALE; NEPHRECTOMY; PROTEINURIA; RATS; RATS, WISTAR; RECEPTORS, GABA-A; RECEPTORS, GABA-B; TIME FACTORS;

EID: 34147165198     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.30.687     Document Type: Article

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