Clinicopathological findings in dogs with distemper encephalomyelitis presented without characteristic signs of the disease

Research in Veterinary Science

Volumn 82, Issue 3, 2007, Pages 416-422

  Amude, A M ^a   Alfieri, A A ^a   Alfieri, A F ^a  

^a STATE UNIVERSITY OF LONDRINA   (Brazil)

Author keywords

Canine distemper virus; Cerebrospinal fluid; Encephalomyelitis; Hemogram; Histopathology; RT PCR

Indexed keywords

ANIMAL TISSUE; ARTICLE; AUTOPSY; CANINE DISTEMPER MORBILLIVIRUS; CEREBROSPINAL FLUID ANALYSIS; CHRONIC DISEASE; CLINICAL FEATURE; CONTROLLED STUDY; DOG DISEASE; ENCEPHALOMYELITIS; HEMATOLOGY; HISTOPATHOLOGY; HOSPITAL ADMISSION; MYOCLONUS; NEUROLOGIC DISEASE; NONHUMAN; PLEOCYTOSIS; QUADRIPLEGIA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYMPTOM; VIRUS INFECTION;

ANIMALS; CEREBELLUM; DISTEMPER; DOGS; ENCEPHALOMYELITIS;

CANINE DISTEMPER VIRUS; CANIS FAMILIARIS;

EID: 34147136620     PISSN: 00345288     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rvsc.2006.08.008     Document Type: Article

References (30)

1. Amude A.M., Alfieri A.A., and Alfieri A.F. Antemortem diagnosis of CDV infection by RT-PCR in distemper dogs with neurological deficits without the typical clinical presentation. Veterinary Research Communication 30 (2006) 679-687
2. Amude A.M., Alfieri A.A., Balarin M.R.S., Faria dos Reis A.C., and Alfieri A.F. Cerebrospinal fluid from a 7-month-old dog with seizure-like episodes. Veterinary Clinical Pathology Journal 35 (2006) 119-122
3. Amude A.M., Carvalho G.A., Balarin M.R.S., Arias M.V.B., Faria dos Reis A.C., Alfieri A.A., and Alfieri A.F. Encefalomielite pelo vírus da cinomose canina em cães sem sinais sistêmicos da doença - estudos preliminares em três casos (Canine distemper encephalomyelitis in dogs without systemic signs of the disease - preliminary studies in three cases). Clínica Veterinária 60 (2006) 60-66
4. Boom R., Sol C.J.A., Salimans M.M.M., Jansen C.L., Werthein-van Dillen P.M.E., and Vander Noordaa J. Rapid and simple method for purification of nucleic acids. Journal of Clinical Microbiology 28 (1990) 495-503
5. Braund K.G. Clinical Syndromes in Veterinary Neurology. second ed. (1994), Mosby, St Louis, MO p. 476
6. Chrisman C.L. Cerebrospinal fluid analysis. The Veterinary Clinics of North America: Small Animal Practice 22 (1992) 781-807
7. Fauquet C.M., Mayo M.A., Maniloff J., Desselberger V., and Ball L.A. Virus Taxonomy. The Light Report (2004), Academic Press, San Diego
8. Frisk A.L., Konig M., Moritz A., and Baumgärtner W. Detection of canine distemper virus nucleoprotein RNA by reverse transcription-PCR using serum, whole blood, and cerebrospinal fluid from dogs with distemper. Journal of Clinical Microbiology 37 (1999) 3634-3643
9. Gebara C.M.S., Wosiacki S.R., Negrão F.J., Alfieri A.A., and Alfieri A.F. Lesões histopatológicas no sistema nervoso central de cães com encefalite e diagnóstico molecular da infecção pelo vírus da cinomose canina (Histopathological lesions in the central nervous system of dogs with encephalitis and molecular diagnosis of canine distemper virus infection). Arquivos Brasileiros de Medicina Veterinária e Zootecnia 56 (2004) 168-174
10. Gebara C.M.S., Wosiacki S.R., Negrão F.J., de Oliveira D.B., Beloni S.N.B., Alfieri A.A., and Alfieri A.F. Detecção do gene da nucleoproteína do vírus da cinomose canina por RT-PCR em urina de cães com sinais clínicos de cinomose (Detection of canine distemper virus nucleoprotein gene by RT-PCR in urine of dogs with clinical signs). Arquivos Brasileiros de Medicina Veterinária e Zootecnia 56 (2004) 480-487
11. Greene G.E., and Appel M.J. Canine distemper. In: Greene G.E. (Ed). Infectious Diseases of Dog and the Cat. second ed. (1998), W.B. Saunders, Philadelphia 9-22
12. Headley S.A., Soares I.C., and Graça D.L. Glial fibrillary acidic protein (GFAP) - immunoreactive astrocytes in dogs infected with canine distemper virus. Journal of Comparative Pathology 125 (2001) 90-97
13. Jóźwik A., and Frymus T. Comparison of the immunofluorescence assay with RT-PCR and nested PCR in the diagnosis of canine distemper. Veterinary Research Communications 29 (2005) 347-359
14. Koutinas A.F., Polizopoulou Z.S., Baumgärtner W., Lekkas S., and Kontos V. Relation of clinical sings to pathological changes in 19 cases of canine distemper encephalomyelitis. Journal of Comparative Pathology 126 (2002) 47-56
15. Moritz A., Frisk A.L., and Baumgärtner W. The evaluation of diagnostic procedures for the detection of canine distemper virus infection. European Journal of Companion Animal Practice 10 (2000) 37-47
16. Muller C.F., Fatzer R.S., Beck K., Vandevelde M., and Zurbriggen A. Studies on canine distemper virus persistence in the central nervous system. Acta Neuropathologica 89 (1995) 438-445
17. Palmer D.G., Huxtable C.R.R., and Thomas J.B. Immuhistochemical demonstration of canine distemper virus antigen as an aid in the diagnosis of distemper encephalomyelitis. Research in Veterinary Science 49 (1990) 177-181
18. Parker A.J. The many faces of canine distemper. Canine Practice 5 (1978) 25-28
19. Saito T.B., Alfieri A.A., Wosiacki S.R., Negrão F.J., Morais H.S.A., and Alfieri A.F. Detection of canine distemper virus by reverse transcription-polimerase chain reaction in the urine of dogs with clinical signs of distemper encephalitis. Research in Veterinary Science 80 (2006) 116-119
20. Shell L.G. Canine distemper. The Compendiun on Continuing Education for the Practicing Veterinarian 12 (1990) 173-179
21. Shin Y., Mori T., Okita M., Gemma T., Kai C., and Mikami T. Detection of canine distemper virus nucleocapsid protein gene in canine peripheral blood mononuclear cells by RT-PCR. Journal of Veterinary Medical Science 57 (1995) 439-445
22. Summer B.A., Cummings J.F., and de Lahunta A. Veterinary Neuropatology (1995), Mosby, St Louis pp. 102-110
23. Thomas W.B., Sorjonen D.C., and Steiss J.E. A retrospective evaluation of 38 cases of canine distemper encephalomyelitis. Journal of the American Animal Hospital Association 29 (1993) 129-133
24. Tipold A., Vandevelde M., and Jaggy A. Neurological manifestation of canine distemper virus infection. Journal of Small Animal Practice 33 (1992) 466-470
25. Tipold A., Jaggy A., Zurbriggen A., and Vandevelde M. Neurological signs in canine distemper encephalomyelitis - a clinical study. European Journal of Companion Animal Practice 7 (1996) 33-38
26. Tudury A.E., Arias M.V.B., Bracarense A.P.F.L., Megid J., and Dias Jr. R.F. Observações Clínicas e Labotaroriais em Cães com Cinomose Nervosa. Ciência Rural 27 (1997) 229-235
27. Vandevelde M., and Cachin M. The neurologic form of canine distemper. In: Bonagura J.D., and Kirk R.W. (Eds). Kirk's Current Veterinary Therapy XI, Small Animal Practice (1993), W.B. Saunders, Philadelphia 1003-1007
28. Vandevelde M., and Zurbriggen A. The neurobiology of canine distemper virus infection. Veterinary Microbiology 44 (1995) 271-280
29. Vandevelde M., Kristensen B., Braund K.G., Greene C.E., Swango L.J., and Hoerlein B.F. Chronic canine distemper virus encephalitis in mature dogs. Veterinary Pathology 17 (1980) 17-28
30. Vandevelde M., Fankhauser R., Kristensen F., and Kristensen B. Immunoglobulins in demyelinating lesions in canine distemper encephalolyelitis - an immunohistological study. Acta Neuropathologica 54 (1981) 31-41