Histopathological lesions in the central nervous system of dogs with encephalitis and molecular diagnosis of canine distemper virus infection;Lesões histológicas no sistema nervoso central de cães com encefalite e diagnóstico molecular da infecção pelo vírus da cinomose canina

Arquivo Brasileiro de Medicina Veterinaria e Zootecnia

Volumn 56, Issue 2, 2004, Pages 168-174

  Gebara, C M S ^a   Wosiacki, S R ^a   Negrao F J ^a   Alfieri, A A ^a   Alfieri, A F ^a  

^a STATE UNIVERSITY OF LONDRINA   (Brazil)

Author keywords

Canine distemper; Canine distemper virus; Dog; Histopathology; RT PCR

Indexed keywords

VIRUS RNA;

ACUTE DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPSY; BLADDER; BRAIN INJURY; CADAVER; CANINE DISTEMPER MORBILLIVIRUS; CENTRAL NERVOUS SYSTEM; CEREBELLUM; CHRONIC DISEASE; CLINICAL FEATURE; CONTROLLED STUDY; DEATH; DIAGNOSTIC PROCEDURE; DOG; ENCEPHALITIS; HISTOPATHOLOGY; NEUROLOGIC DISEASE; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SAMPLING; SYSTEMIC DISEASE; URINALYSIS; VIRUS INFECTION;

ANIMALIA; CANINE DISTEMPER VIRUS; CANIS FAMILIARIS;

EID: 4143132043     PISSN: 01020935     EISSN: None     Source Type: Journal    
DOI: 10.1590/s0102-09352004000200005     Document Type: Article

References (24)

1. ANDERSON, E.C. Morbillivirus infections in wildlife (in relation to their population biology and disease control in domestic animals). Vet. Microbiol., v.44, p.319-332, 1995.
2. APPEL, M.J.G. Pathogenesis of canine distemper. Am. J. Vet. Res., v.30, p.1167-1182, 1969.
3. APPEL, M.J.G.; SUMMERS, B.A. Canine distemper: Current Status, 1999. Disponível em: 〈http://www.ivis.org/〉 Acesso em: 13 mar. 2002.
4. APPEL, M.J.G.; SUMMERS, B.A. Pathogenicity of morbilliviruses for terrestrial carnivores. Vet. Microbiol., v.44, p.187-191, 1995.
5. BEHMER, O.A.; TOLOSA, E.M.C.; FREITAS, N.A.G. Manual de técnicas para histologia normal e patológica. São Paulo: EDART, 1976. 241p.
6. BOOM, R.; SOL, C.J.A.; SALIMANS, M.M.M. et al. Rapid an simple method for purification of nucleic acids. J. Clin. Microbiol., v.28, p.495-503, 1990.
7. BRAUND, K.G. Clinical syndromes in veterinary neurology. 2.ed. St. Louis: Mosby, 1994. 477p.
8. CARLTON, W.W.; McGAVIN, M. Patologia veterinária especial. 2.ed. Porto Alegre: ArtMed. 1998. 672p.
9. FENNER, F. Veterinary virology. Londres: Academic Press, 1987. 445p.
10. FRISK, A.L.; KONIG, M.; MORITZ, A. et al. Detection of canine distemper virus nucleoprotein RNA by reverse transcription-PCR using serum, whole blood, and cerebrospinhal fluid from dogs with distemper. J. Clin. Microbiol., v.37, p.3634-3643, 1999.
11. GEBARA, C.M.S. Achados clínicos e histopatológicos em cães com diagnóstico molecular do vírus da cinomose canina. 2002. 94f. Dissertação (Mestrado em Sanidade Animal)- Centro de Ciências Agrárias, Universidade Estadual de Londrina, Londrina, PR.
12. GREENE, G.E. Infectious diseases of the dog and the cat. Philadelphia: W.B. Saunders, 1998. 820p.
13. HEADLEY, S.A.; GRAÇA, D.L. Canine distemper: epidemiological findings of 250 cases. Braz. J. Vet. Res. Anim. Sci., v.37, p.136-140, 2000.
14. HEADLEY, S.A.; GRAÇA, D.L.; SOARES, I.C. Glial fibrillary acidic protein (GFAP) immunoreactive astrocytes in dogs infected with canine distemper virus. J. Comp. Pathol., v.125, p.90-97, 2001.
15. JONES, C.T.; HUNT, D.H.; KING, N.W. Patologia veterinária. São Paulo: Manole, 2000. 1415p.
16. MOTOHASHI, T.; NAKAGAWA, H.; OKADA, T. Fluorescent antibody technique in diagnosis of canine distemper. Vet. Med. Small Anim. Clin., v.65, p.1057-1059, 1969.
17. RUDE, T.A. Canine distemper vírus: Infection and prevention. Canine Pract., v.14, p.16-24, 1987.
18. SAITO, T.B. Padronização da técnica da Reação em Cadeia pela Polimerase (RT-PCR) para o diagnóstico ante e post mortem do vírus da cinomose canina. Londrina, 2001. 100f. Dissertação (Mestrado em Sanidade Animal)-Centro de Ciências Agrárias, Universidade Estadual de Londrina, Londrina, PR.
19. SHELL, L.G. Canine distemper. Comp. Small Anim., v.12, p.173-179, 1990.
20. SHEN, D.T.; GORHAM, J.R.; PERDERSEN, V. Viriuria in dogs infected with canine distemper. Vet. Med. Small Anim. Clin., v.76, p.1175-1177, 1981.
21. SHIN, Y.; MORI, T.; OKITA, M. et al. Detection of canine distemper virus nucleocapsid protein gene in canine peripheal blood mononuclear cells by RT-PCR. J. Vet. Med. Sci., v.57, p.439-45, 1995.
22. STETTLER, M.; ZUBRIGGEN, A. Nucleotide and deduced aminoacid sequences of the nucleocapsid protein of the virulent A75/17-CDV strain of canine distemper virus, Vet. Microbiol., v.44, p.211-217, 1995.
23. TIPOLD, A. Diagnosis of inflamatory and infectious diseases of the central nervous system in dogs: a retrospective study. J. Vet. Int. Med., v.9, p.304-314, 1995.
24. ZUBRIGGEN, A.; GRABER, H.U.; VANDELVEDE, M. Seletive spread and reduced virus release leads to canine distemper virus persistence in the nervous system. Vet. Microbiol., v.44, p.281-288, 1995.