Orthopaedic metal devices coated with a novel antiseptic dye for the prevention of bacterial infections

International Journal of Antimicrobial Agents

Volumn 29, Issue 5, 2007, Pages 593-596

  Bahna, Paul ^a   Dvorak, Tanya ^a   Hanna, Hend ^a   Yasko, Alan W ^a   Hachem, Ray ^a   Raad, Issam ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Bacteria; Bone repair; Infection; Metal surface treatment

Indexed keywords

ANTIINFECTIVE AGENT; CHLORHEXIDINE; CRYSTAL VIOLET; GENDINE; STAINLESS STEEL; TITANIUM; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL TISSUE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL INFECTION; BACTERIUM ADHERENCE; BIOFILM; BONE; COLONY FORMING UNIT; CONTROLLED STUDY; COW; GAMMA IRRADIATION; KIRBY BAUER METHOD; KUHN METHOD; MATERIAL COATING; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; ORTHOPEDIC EQUIPMENT; PRIORITY JOURNAL; RADIATION DOSE; SCHANZ ROD; SERUM;

ANTI-INFECTIVE AGENTS, LOCAL; BACTERIAL ADHESION; CHLORHEXIDINE; COLORING AGENTS; DRUG STABILITY; GAMMA RAYS; GENTIAN VIOLET; METALS; METHICILLIN RESISTANCE; METHYLENE CHLORIDE; MICROBIAL SENSITIVITY TESTS; PROSTHESIS-RELATED INFECTIONS; STAPHYLOCOCCUS AUREUS; STEEL; STERILIZATION; TITANIUM;

EID: 34147131951     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2006.12.013     Document Type: Article

References (15)

1. Zimmerli W., Trampuz A., and Ochsner P.E. Prosthetic-joint infections. N Engl J Med 351 (2004) 1645-1654
2. Sanderson P.J. Infection in orthopedic implants. J Hosp Infect 18 Suppl. A (1991) 367-375
3. Court-Brown C.M., Keating J.F., and McQween M.M. Infection after intramedullary nailing of tibia. Incidence and protocol for management. J Bone Joint Surg Br 74 (1992) 770-774
4. Costerton J.W., Stewart P.S., and Greenberg E.P. Bacterial biofilms: a common cause of persistent infections. Science 284 (1999) 1318-1322
5. Chaiban G., Hanna H., Dvorak T., and Raad I. A rapid method of impregnating endotracheal tubes and urinary catheters with gendine: a novel antiseptic agent. J Antimicrob Chemother 55 (2004) 51-56
6. Nabulsi N, Hanna H, Raad I. Devices impregnated with novel antiseptic agents: broad-spectrum activity and prolonged antimicrobial durability. In: Program and Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC); 16-19 December 2001; Chicago, IL. Washington, DC: American Society for Microbiology; 2001. p. 434. [abstract K-1459].
7. American National Standards Institute/Association for the Advancement of Medical Instrumentation. Sterilization of healthcare products-requirements for validation and routine control. Radiation sterilization with Amendment 1. ANSI/AAMI/ISO 11137; 1994.
8. Bauer A.W., Kirby W.M., Sherris J.C., and Turck M. Antibiotic susceptibility testing by a standardized single disk method. Am J Clin Pathol 45 (1966) 493-496
9. Kuhn D.M., Chandra J., Mukherjee P.K., and Ghannoum M.A. Comparison of biofilms formed by Candida albicans and Candida parapsilosis on bioprosthetic surfaces. Infect Immun 70 (2002) 878-888
10. Darouiche R.O. Anti-infective efficacy of silver-coated medical prostheses. Clin Infect Dis 29 (1999) 1371-1377
11. Nablo B.J., Rothrock A., and Schoenfisch N.H. Nitric oxide-releasing sol-gels as antibacterial coatings for orthopedic implants. Biomaterials 26 (2005) 917-924
12. Lucke M., Schmidmaier G., Sadoni S., et al. Gentamicin coating of metallic implants reduces implant-related osteomyelitis in rats. Bone 32 (2003) 521-531
13. DeJong E., DeBerardino T.M., Brooks D.E., et al. Antimicrobial efficacy of external fixator pins coated with a lipid stabilized hydroxyapatite/chlorhexidine complex to prevent pin tract infection in a goat model. J Trauma 50 (2001) 1008-1014
14. Nelson BJ, DeBerardino TM, Brooks DE, et al. The efficacy of steel, silver-coated, and antiseptic-coated external fixator pins in preventing pin tract infections in a caprine model. In: Program and Abstracts of the 66th Annual Meeting of the American Academy of Orthopedic Surgeons; 6 February 1999; Anaheim, CA. Rosemont, IL: American Academy of Orthopedic Surgeons; 1999. p. 81. [abstract 289].
15. Marotta J.S., Coupe E.J., Milner R., and Heseltine K.E. Long-term bactericidal properties of a gentamicin-coated antimicrobial external fixation pin sleeve. J Bone Joint Surg Am 85 (2003) 129-131