A rapid method of impregnating endotracheal tubes and urinary catheters with gendine: A novel antiseptic agent

Journal of Antimicrobial Chemotherapy

Volumn 55, Issue 1, 2005, Pages 51-56

  Chaiban, Gassan ^a   Hanna, Hend ^a   Dvorak, Tanya ^a   Raad, Issam ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

Antimicrobial activity; Bacterial adherence; Gentian Violet; Medical devices; Novel antiseptics

Indexed keywords

ANTIINFECTIVE AGENT; CRYSTAL VIOLET PLUS CHLORHEXIDINE; GENDINE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL INFECTION; BACTERIUM ADHERENCE; CANDIDA PARAPSILOSIS; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; DRUG INHIBITION; ELUTION; ENDOTRACHEAL TUBE; ESCHERICHIA COLI; FIBROBLAST; HOSPITAL INFECTION; HYDROGEL; MATERIAL COATING; MEDICAL INSTRUMENTATION; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MOUSE; NONHUMAN; PNEUMONIA; PSEUDOMONAS AERUGINOSA; URINARY TRACT INFECTION; URINE CATHETER;

ANIMALS; ANTI-INFECTIVE AGENTS, LOCAL; BACTERIAL ADHESION; CANDIDA; CATHETERS, INDWELLING; CHLORHEXIDINE; COATED MATERIALS, BIOCOMPATIBLE; DISINFECTANTS; EQUIPMENT CONTAMINATION; ESCHERICHIA COLI; GENTIAN VIOLET; HUMANS; INTUBATION, INTRATRACHEAL; L CELLS (CELL LINE); METHICILLIN RESISTANCE; MICE; MICROBIAL SENSITIVITY TESTS; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; TIME FACTORS; URINARY CATHETERIZATION;

EID: 13244273457     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/dkh499     Document Type: Article

References (29)

1. Saint, S., Veenstra, D. L., Sullivan, S. D. et al. (2000). The potential clinical and economic benefits of silver alloy urinary catheters in preventing urinary tract infection. Archives of Internal Medicine 160, 2670-5.
2. Haley, R. W., Hooton, T. M., Culver, D. H. et al. (1981). Nosocomial infections in U.S. Hospitals, 1975-1976, Estimated frequency by selected characteristics of patients. American Journal of Medicine 70, 947-59.
3. Stickler, D. J. (2002). Susceptibility of antibiotic-resistant Gram-negative bacteria to biocides: a perspective from the study of catheter biofilms. Journal of Applied Microbiology Symposium Supplement 92, 163S-70S.
4. Koemer, R. J. (1997). Contribution of endotracheal tubes to the pathogenesis of ventilator-associated pneumonia. Journal of Hospital Infection 35, 83-9.
5. Meduri, G. U. (1992). International Consensus Conference: clinical investigation of ventilator-associated pneumonia. Introduction. Chest 102, 551S-2S.
6. Weber, D. J. & Rutala, W. A. (1999). Nosocomial infections associated with respiratory therapy. In Hospital Epidemiology and Infection Control, 2nd edn (Mayhall, C. G., Ed.). Lippincott Williams & Wilkins, Philadelphia, PA, USA.
7. Maki, D. G. & Tambyah, P. A. (2001). Engineering out the risk for infection with urinary catheters. Emerging Infectious Diseases 7, 342-7.
8. Kuhn, D. M., George, T., Chandra, J. et al. (2002). Antifungal susceptibility of Candida biofilms: unique efficacy of amphotericin B lipid formulations and echinocandins. Antimicrobial Agents and Chemotherapy 46, 1773-80.
9. Raad, I. I., Hanna, H. A. & Nabulsi, N. (2003). Novel antiseptic derivatives with broad-spectrum antimicrobial activity for the impregnation of surfaces. United States Patent Publication No. US 200310078242A1, April 24, 2003.
10. Sherertz, R. J., Carruth, W. A., Hampton, A. A. et al. (1993). Efficacy of antibiotic-coated catheters in preventing subcutaneous Staphylococcus aureus infections in rabbits. Journal of Infectious Diseases 167, 98-106.
11. Craig, C. P. & Connelly, S. (1984). Effect of intensive care unit nosocomial pneumonia on duration of stay and mortality. American Journal of Infection Control 12, 233-8.
12. Greene, R., Thompson, S., Jantsch, H. et al. (1994). Detection of pooled secretions above endotracheal-tube cuffs: value of plain radiographs in sheep cadavers and patients. American Journal of Roentgenology 163, 1333-7.
13. Sottile, F. D., Marrie, T. J., Prough, D. S. et al. (1986). Nosocomial pulmonary infection: possible etiologic significance of bacterial adhesion to endotracheal tubes. Critical Care Medicine 14, 265-70.
14. Heyland, D. K., Cook, D. J., Griffith, L. et al. (1999). The attributable morbidity and mortality of ventilator-associated pneumonia in the critically ill patient. American Journal of Respiratory and Critical Care Medicine 159, 1249-56.
15. Bassetti, S., Hu, J., D'Agostino, R. B. et al. (2000). In vitro zones of inhibition of coated vascular catheters predict efficacy in preventing catheter infection with Staphylococcus aureus in vivo. European Journal of Clinical Microbiology and Infectious Disease 19, 612-7.
16. Smulders, K., Van der Hoeven, H., Weers-Pothoff, I. et al. (2002). A randomized clinical trial of intermittent subglottic secretion drainage in patients receiving mechanical ventilation. Chest 121, 858-62.
17. Richards, M. J., Edwards, J. R., Culver, D. H. et al. (1999). Nosocomial infections in medical intensive care units in the United States. Critical Care Medicine 27, 887-92.
18. Centers for Disease Control. (1992). Public health focus: surveillance, prevention, and control of nosocomial infections. Morbidity and Mortality Weekly Report 41, 783-7.
19. Emori, T. G. & Gaynes, R. P. (1993). An overview of nosocomial infections, including the role of microbiology laboratory. Clinical Microbiology Reviews 6, 428-42.
20. Karchmer, T. B., Giannetta, E. T., Muto, C. A. et al. (2000). A randomized crossover study of silver-coated urinary catheters in hospitalized patients. Archives of Internal Medicine 160, 3294-8.
21. Riley, D. K., Classen, D. C., Stevens, L. E. et al. (1995). A large randomized clinical trial of a silver-impregnated urinary catheter: lack of efficacy and staphylococcal superinfection. American Journal of Medicine 98, 349-56.
22. Darouiche, R. O., Raad, I. I., Heard, S. O. et al. (1999). A comparison of two antimicrobial-impregnated central venous catheters. New England Journal of Medicine 240, 1-8.
23. Darouiche, R. O., Smith, J. A., Hanna, H. et al. (1999). Efficacy of antimicrobial-impregnated bladder catheters in reducing catheter-associated bacteriuria: a prospective, randomized, multicenter clinical trial. Urology 54, 976-81.
24. Raad, I., Darouiche, R., Dupuis, J. et al. (1997). Central venous catheters coated with minocycline and rifampin for the prevention of catheter-related colonization and bloodstream infections. Annals of Internal Medicine 127, 267-74.
25. Tambe, S. M., Sampath, L. & Modak, S. M. (2001). In vitro evaluation of the risk of developing bacterial resistance to antiseptics and antibiotics used in medical devices. Journal of Antimicrobial Chemotherapy 47, 589-98.
26. Saji, M., Taguchi, S., Uchiyama, K. et al. (1995). Efficacy of gentian violet in the eradication of methicillin-resistant Staphylococcus aureus from skin lesions. Journal of Hospital Infection 31, 225-8.
27. Vazquez, J. A. (1999). Options for the management of mucosal candidiasis in patients with AIDS and HIV infection. Pharmacotherapy 19, 76-87.
28. George, S. J., Vuddamalay, P. & Boscoe, M. J. (1997). Antiseptic-impregnated central venous catheters reduce the incidence of bacterial colonization and associated infection in immunocompromised transplant patients. European Journal of Anaesthesiology 14, 428-31.
29. Maki, D. G., Stolz, S. M., Wheeler, L. A. et al. (1997). Prevention of central venous catheter-related bloodstream infection by use of an antiseptic-impregnated catheter. A randomized, controlled trial. Annals of Internal Medicine 127, 257-66.