-
1
-
-
0027993707
-
Efficacy and safety profile of gemcitabine in non-small cell lung cancer: A phase II study
-
Abratt RP, Bezwoda WR, Falkson G., Goedhals L., Hacking D., and Rugg TA (1994) Efficacy and safety profile of gemcitabine in non-small cell lung cancer: A phase II study. J Clin Oncol 12: 1535-1540.
-
(1994)
J Clin Oncol
, vol.12
, pp. 1535-1540
-
-
Abratt, R.P.1
Bezwoda, W.R.2
Falkson, G.3
Goedhals, L.4
Hacking, D.5
Rugg, T.A.6
-
2
-
-
0032914652
-
Circadian variation in the expression of cell-cycle proteins in human oral epithelium
-
Bjarnason GA, Jordan Rck, and Sothern RB (1999) Circadian variation in the expression of cell-cycle proteins in human oral epithelium. Am J Pathol 154: 613-622.
-
(1999)
Am J Pathol
, vol.154
, pp. 613-622
-
-
Bjarnason, G.A.1
Rck, J.2
Sothern, R.B.3
-
3
-
-
0030049697
-
Phase II study of gemcitabine in patients with advanced pancreatic cancer
-
Carmichael J., Fink U., Russell Rcg, Spittle MF, Harris AL, Spiessi G., and Blatter J. (1996) Phase II study of gemcitabine in patients with advanced pancreatic cancer. Br J Cancer 73: 101-105.
-
(1996)
Br J Cancer
, vol.73
, pp. 101-105
-
-
Carmichael, J.1
Fink, U.2
Rcg, R.3
Spittle, M.F.4
Harris, A.L.5
Spiessi, G.6
Blatter, J.7
-
4
-
-
0028799915
-
Advanced breast cancer: A phase II trial with gemcitabine
-
Carmichael J., Possinger K., Phillip P., Beykirch M., Kerr H., Walling J., and Harris AL (1995) Advanced breast cancer: a phase II trial with gemcitabine. J Clin Oncol 13: 2731-2736.
-
(1995)
J Clin Oncol
, vol.13
, pp. 2731-2736
-
-
Carmichael, J.1
Possinger, K.2
Phillip, P.3
Beykirch, M.4
Kerr, H.5
Walling, J.6
Harris, A.L.7
-
5
-
-
0038007345
-
Prolonged gemcitabine infusion in advanced non-small cell lung carcinoma: A randomized phase II study of two different schedules in combination with cisplatin
-
Ceribelli A., Gridelli C., De Marinis F, Fabi A., Gamucci T., Cortesi E., Barduagni M., Antimi M., Maione P., Migliorino MR, et al. (2003) Prolonged gemcitabine infusion in advanced non-small cell lung carcinoma: a randomized phase II study of two different schedules in combination with cisplatin. Cancer 98: 337-343.
-
(2003)
Cancer
, vol.98
, pp. 337-343
-
-
Ceribelli, A.1
Gridelli, C.2
De Marinis, F.3
Fabi, A.4
Gamucci, T.5
Cortesi, E.6
Barduagni, M.7
Antimi, M.8
Maione, P.9
Migliorino, M.R.10
-
6
-
-
0037161808
-
Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus
-
Cheng MY, Bullock CM, Li C., Lee AG, Bermak JC, Belluzzi J., Weaver DR, Leslie FM, and Zhou QY (2002) Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus. Nature 417: 405-410.
-
(2002)
Nature
, vol.417
, pp. 405-410
-
-
Cheng, M.Y.1
Bullock, C.M.2
Li, C.3
Lee, A.G.4
Bermak, J.C.5
Belluzzi, J.6
Weaver, D.R.7
Leslie, F.M.8
Zhou, Q.Y.9
-
7
-
-
0035544163
-
Gemcitabine-induced systemic capillary leak syndrome
-
De Pas T., Curigliano G., Franceschelli L., Catania C., Spaggiari L., and de Braud F. (2001) Gemcitabine-induced systemic capillary leak syndrome. Ann Oncol 12: 1651-1652.
-
(2001)
Ann Oncol
, vol.12
, pp. 1651-1652
-
-
De Pas, T.1
Curigliano, G.2
Franceschelli, L.3
Catania, C.4
Spaggiari, L.5
De Braud, F.6
-
8
-
-
0029908469
-
Circadian rhythms and the pharmacology of affective illness
-
Duncan WC (1996) Circadian rhythms and the pharmacology of affective illness. Pharmacol Ther 71: 253-312.
-
(1996)
Pharmacol Ther
, vol.71
, pp. 253-312
-
-
Duncan, W.C.1
-
9
-
-
33745329809
-
The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification
-
Gachon F., Olela FF, Schaad O., Descombes P., and Schibler U. (2006) The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification. Cell Metab 4: 25-36.
-
(2006)
Cell Metab
, vol.4
, pp. 25-36
-
-
Gachon, F.1
Olela, F.F.2
Schaad, O.3
Descombes, P.4
Schibler, U.5
-
10
-
-
33747060772
-
Phase III trial comparing 4-day chronomodulated therapy versus 2-day conventional delivery of fluorouracil, leucovorin, and oxaliplatin as first-line chemotherapy of metastatic colorectal cancer: The European Organisation for Research and Treatment of Cancer Chronotherapy Group
-
Giacchetti S., Bjarnason G., Garufi C., Genet D., Iacobelli S., Tampellini M., Smaaland R., Focan C., Coudert B., Humblet Y., et al. (2006) Phase III trial comparing 4-day chronomodulated therapy versus 2-day conventional delivery of fluorouracil, leucovorin, and oxaliplatin as first-line chemotherapy of metastatic colorectal cancer: The European Organisation for Research and Treatment of Cancer Chronotherapy Group. J Clin Oncol 24: 3562-3569.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3562-3569
-
-
Giacchetti, S.1
Bjarnason, G.2
Garufi, C.3
Genet, D.4
Iacobelli, S.5
Tampellini, M.6
Smaaland, R.7
Focan, C.8
Coudert, B.9
Humblet, Y.10
-
11
-
-
13244296954
-
Circadian regulation of cell cycle and apoptosis proteins in mouse bone marrow and tumor
-
Granda TG, Liu XH, Smaaland R., Cermakian N., Filipski E., Sassone-Corsi P., and Lévi F. (2005) Circadian regulation of cell cycle and apoptosis proteins in mouse bone marrow and tumor. FASEB J 19: 304-306.
-
(2005)
FASEB J
, vol.19
, pp. 304-306
-
-
Granda, T.G.1
Liu, X.H.2
Smaaland, R.3
Cermakian, N.4
Filipski, E.5
Sassone-Corsi, P.6
Lévi, F.7
-
12
-
-
0021956173
-
Circadian timing of cancer chemotherapy
-
Hrushesky W. (1985) Circadian timing of cancer chemotherapy. Science 228: 73-75.
-
(1985)
Science
, vol.228
, pp. 73-75
-
-
Hrushesky, W.1
-
13
-
-
0028022127
-
Gemcitabine: Current status of phase I and II trials
-
Kaye SB (1994) Gemcitabine: Current status of phase I and II trials. J Clin Oncol 12: 1527-1531.
-
(1994)
J Clin Oncol
, vol.12
, pp. 1527-1531
-
-
Kaye, S.B.1
-
14
-
-
0035930732
-
Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signaling
-
Kramer A., Yang FC, Snodgrass P., Li X., Scammell TE, Davis FC, and Weitz CJ (2001) Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signaling. Science 294: 2511-2515.
-
(2001)
Science
, vol.294
, pp. 2511-2515
-
-
Kramer, A.1
Yang, F.C.2
Snodgrass, P.3
Li, X.4
Scammell, T.E.5
Davis, F.C.6
Weitz, C.J.7
-
15
-
-
31544474606
-
A role for cardiotrophin-like cytokine in the circadian control of mammalian locomotor activity
-
Kraves S. and Weitz CJ (2006) A role for cardiotrophin-like cytokine in the circadian control of mammalian locomotor activity. Nat Neurosci 9: 212-219.
-
(2006)
Nat Neurosci
, vol.9
, pp. 212-219
-
-
Kraves, S.1
Weitz, C.J.2
-
16
-
-
0008832218
-
Cisplatine Murine Chrononephrotoxicity Gauged by Two Marker Rhythms: Urine Volume and Telemetered Intraperitoneal Temperature
-
University Presses of Florida, Tallahassee.
-
Lévi F., Cornelissen G., Nelson W., and Halberg F. (1981) Cisplatine murine chrononephrotoxicity gauged by two marker rhythms: Urine volume and telemetered intraperitoneal temperature. In Chronopharmacology, Walter CA, Soliman KFA, and Winger W, eds, pp 363-377, University Presses of Florida, Tallahassee.
-
(1981)
Chronopharmacology
, pp. 363-377
-
-
Lévi, F.1
Cornelissen, G.2
Nelson, W.3
Halberg, F.4
Walter, C.A.5
Kfa, S.6
Winger, W.7
-
17
-
-
85083139014
-
Implications of circadian clocks for the rhythmic delivery of cancer therapeutics
-
Lévi F., Focan C., Karaboué A., de la Valette V., Focan-Henrard D., Baron B., Kreutz M., and Giacchetti S. (In press) Implications of circadian clocks for the rhythmic delivery of cancer therapeutics. Adv Drug Deliv Rev.
-
Adv Drug Deliv Rev
-
-
Lévi, F.1
Focan, C.2
Karaboué, A.3
De La Valette, V.4
Focan-Henrard, D.5
Baron, B.6
Kreutz, M.7
Giacchetti, S.8
-
18
-
-
33847075354
-
Circadian rhythms: Mechanisms and therapeutic implications
-
Lévi F. and Schibler U. (2007) Circadian rhythms: Mechanisms and therapeutic implications. Annu Rev Pharmacol Toxicol 47: 593-628.
-
(2007)
Annu Rev Pharmacol Toxicol
, vol.47
, pp. 593-628
-
-
Lévi, F.1
Schibler, U.2
-
19
-
-
0041055512
-
Randomized multi-centre trial of chronotherapy with oxaliplatin, fluorouracil, and folinic acid in metastatic colorectal cancer
-
Lévi F., Zidani R., and Misset JL (1997) Randomized multi-centre trial of chronotherapy with oxaliplatin, fluorouracil, and folinic acid in metastatic colorectal cancer. Lancet 350: 681-686.
-
(1997)
Lancet
, vol.350
, pp. 681-686
-
-
Lévi, F.1
Zidani, R.2
Misset, J.L.3
-
20
-
-
19944411802
-
Preclinical relevance of dosing time for the therapeutic index of gemcitabine-cisplatin
-
Li XM, Tanaka K., Sun J., Filipski E., Kayitalire L., Focan C., and Lévi F. (2005) Preclinical relevance of dosing time for the therapeutic index of gemcitabine-cisplatin. Br J Cancer 92: 1684-1689.
-
(2005)
Br J Cancer
, vol.92
, pp. 1684-1689
-
-
Li, X.M.1
Tanaka, K.2
Sun, J.3
Filipski, E.4
Kayitalire, L.5
Focan, C.6
Lévi, F.7
-
21
-
-
0036229466
-
Pharmacological effects of vinorelbine on body temperature and locomotor activity circadian rhythms in mice
-
Li XM, Vincenti M., and Lévi F. (2002) Pharmacological effects of vinorelbine on body temperature and locomotor activity circadian rhythms in mice. Chronobiol Int 19: 43-55.
-
(2002)
Chronobiol Int
, vol.19
, pp. 43-55
-
-
Li, X.M.1
Vincenti, M.2
Lévi, F.3
-
22
-
-
33746300580
-
Effects of melatonin administration on oxidative stress and daily locomotor activity patterns in goldfish
-
Lopez-Olmeda JF, Bayarri MJ, Rol de Lama MA, Madrid JA, and Sanchez-Vazquez FJ (2006) Effects of melatonin administration on oxidative stress and daily locomotor activity patterns in goldfish. J Physiol Biochem 62: 17-25.
-
(2006)
J Physiol Biochem
, vol.62
, pp. 17-25
-
-
Lopez-Olmeda, J.F.1
Bayarri, M.J.2
De Lama Ma, R.3
Madrid, J.A.4
Sanchez-Vazquez, F.J.5
-
23
-
-
0028020890
-
Phase II study of gemcitabine (2', 2' -difluorodeoxycytidine) in previously treated ovarian cancer
-
Lund B., Hansen OP, Theilade K., Hansen M., and Neijt JP (1994) Phase II study of gemcitabine (2', 2' -difluorodeoxycytidine) in previously treated ovarian cancer. J Natl Cancer Inst 86: 1530-1533.
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 1530-1533
-
-
Lund, B.1
Hansen, O.P.2
Theilade, K.3
Hansen, M.4
Neijt, J.P.5
-
24
-
-
16244381701
-
Gemcitabine twice weekly as a radiosensitiser for the treatment of brain metastases in patients with carcinoma: A phase I study
-
Maraveyas A., Sgouros J., Upadhyay S., Abdel-Hamid AH, Holmes M., and Lind M. (2005) Gemcitabine twice weekly as a radiosensitiser for the treatment of brain metastases in patients with carcinoma: a phase I study. Br J Cancer 92: 815-819.
-
(2005)
Br J Cancer
, vol.92
, pp. 815-819
-
-
Maraveyas, A.1
Sgouros, J.2
Upadhyay, S.3
Abdel-Hamid, A.H.4
Holmes, M.5
Lind, M.6
-
25
-
-
18744429390
-
Marked 24-h rest/activity rhythms are associated with better quality of life, better response, and longer survival in patients with metastatic colorectal cancer and good performance status
-
Mormont MC, Waterhouse J., Bleuzen P., Giacchetti S., Jami A., Bogdan A., Lellouch J., Misset JL, Touitou Y., and Lévi F. (2000) Marked 24-h rest/activity rhythms are associated with better quality of life, better response, and longer survival in patients with metastatic colorectal cancer and good performance status. Clin Cancer Res 6: 3038-3045.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 3038-3045
-
-
Mormont, M.C.1
Waterhouse, J.2
Bleuzen, P.3
Giacchetti, S.4
Jami, A.5
Bogdan, A.6
Lellouch, J.7
Misset, J.L.8
Touitou, Y.9
Lévi, F.10
-
26
-
-
0036941689
-
Fatigue associated with cancer and its treatment
-
Morrow GR, Andrews Plr, Hickok JT, Roscoe JA, and Matteson S. (2002) Fatigue associated with cancer and its treatment. Support Care Cancer 10: 389-398.
-
(2002)
Support Care Cancer
, vol.10
, pp. 389-398
-
-
Morrow, G.R.1
Plr, A.2
Hickok, J.T.3
Roscoe, J.A.4
Matteson, S.5
-
28
-
-
0035106940
-
Changing the dosing schedule minimizes the disruptive effects of interferon on clock function
-
Ohdo S., Koyanagi S., Suyama H., Higuchi S., and Aramaki H. (2001) Changing the dosing schedule minimizes the disruptive effects of interferon on clock function. Nat Med 7: 356-360.
-
(2001)
Nat Med
, vol.7
, pp. 356-360
-
-
Ohdo, S.1
Koyanagi, S.2
Suyama, H.3
Higuchi, S.4
Aramaki, H.5
-
29
-
-
16344373564
-
Elevated serum cytokines correlated with altered behavior, serum cortisol rhythm, and dampened 24-hour rest-activity patterns in patients with metastatic colorectal cancer
-
Rich T., Innominato PF, Boerner J., Mormont MC, Iacobelli S., Baron B., Jasmin C., and Levi F. (2005) Elevated serum cytokines correlated with altered behavior, serum cortisol rhythm, and dampened 24-hour rest-activity patterns in patients with metastatic colorectal cancer. Clin Cancer Res 11: 1757-1764.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 1757-1764
-
-
Rich, T.1
Innominato, P.F.2
Boerner, J.3
Mormont, M.C.4
Iacobelli, S.5
Baron, B.6
Jasmin, C.7
Levi, F.8
-
30
-
-
0031805646
-
Dependency of hematopoietic growth factor coupled to chronotoxicity of carboplatin
-
Ron IG, Peleg L., Rienstein S., Dotan A., Ticher A., Wolfson S., and Ashkenazi IE (1998) Dependency of hematopoietic growth factor coupled to chronotoxicity of carboplatin. Cancer Chemother Pharmacol 42: 135-141.
-
(1998)
Cancer Chemother Pharmacol
, vol.42
, pp. 135-141
-
-
Ron, I.G.1
Peleg, L.2
Rienstein, S.3
Dotan, A.4
Ticher, A.5
Wolfson, S.6
Ashkenazi, I.E.7
-
31
-
-
0036159592
-
Severe pulmonary toxicity in a patient treated with gemcitabine
-
Rosado MF, Kett DH, Schein RM, Baraona FJ, and Sridhar KS (2002) Severe pulmonary toxicity in a patient treated with gemcitabine. Am J Clin Oncol 25: 31-33.
-
(2002)
Am J Clin Oncol
, vol.25
, pp. 31-33
-
-
Rosado, M.F.1
Kett, D.H.2
Schein, R.M.3
Baraona, F.J.4
Sridhar, K.S.5
-
32
-
-
0027180521
-
2', 2' -Difluorodeoxycytidine (gemcitabine) incorporation into RNA and DNA of tumour cells
-
Ruiz van Haperen Vwt, Veerman G., Vermorken JB, and Peters GJ (1993) 2', 2' -Difluorodeoxycytidine (gemcitabine) incorporation into RNA and DNA of tumour cells. Biochem Pharmacol 46: 762-766.
-
(1993)
Biochem Pharmacol
, vol.46
, pp. 762-766
-
-
Van Haperen Vwt, R.1
Veerman, G.2
Vermorken, J.B.3
Peters, G.J.4
-
33
-
-
33748787454
-
Circadian rhythms of heart rate and locomotion after treatment with low-dose acetylcholinesterase inhibitors
-
Scremin OU, Shih TM, Huynh L., Roch M., Sun W., Chialvo DR, and Jenden DJ (2006) Circadian rhythms of heart rate and locomotion after treatment with low-dose acetylcholinesterase inhibitors. J Appl Toxicol 26: 410-418.
-
(2006)
J Appl Toxicol
, vol.26
, pp. 410-418
-
-
Scremin, O.U.1
Shih, T.M.2
Huynh, L.3
Roch, M.4
Sun, W.5
Chialvo, D.R.6
Jenden, D.J.7
-
34
-
-
4644227840
-
Fatigue and cancer: Causes, prevalence and treatment approaches
-
Wagner LI and Cella D. (2004) Fatigue and cancer: Causes, prevalence and treatment approaches. Br J Cancer 91: 822-828.
-
(2004)
Br J Cancer
, vol.91
, pp. 822-828
-
-
Wagner, L.I.1
Cella, D.2
-
35
-
-
0026440509
-
Modulation of deoxycytidylate deaminase in intact human leukemia cells-Action of 2', 2'-difluorodeoxycytidine
-
Xu YZ and Plunkett W. (1992) Modulation of deoxycytidylate deaminase in intact human leukemia cells-Action of 2', 2'-difluorodeoxycytidine. Biochem Pharmacol 45: 1819-1827.
-
(1992)
Biochem Pharmacol
, vol.45
, pp. 1819-1827
-
-
Xu, Y.Z.1
Plunkett, W.2
|