Barrett's esophagus: Its pathology and neoplastic complications

Esophagus

Volumn 1, Issue 1, 2003, Pages 17-29

  Shepherd, Neil A ^a  

^a GLOUCESTERSHIRE ROYAL HOSPITAL   (United Kingdom)

Author keywords

Adenocarcinoma; Barrett's esophagus; Columnar lined esophagus; Dysplasia; Gastroesophageal reflux

Indexed keywords

EID: 34147091924     PISSN: 16129059     EISSN: 16129067     Source Type: Journal    
DOI: 10.1007/s10388-003-0003-z     Document Type: Article

References (88)

1. Barrett NR. Chronic peptic ulcer of the oesophagus and oesophagitis. Br J Surg 1950;38:175-82.
2. Spechler SJ. The columnar lined oesophagus: a riddle wrapped in a mystery inside an enigma. Gut 1997;41:710-1.
3. Spechler SJ, Goyal RK. The columnar-lined esophagus, intestinal metaplasia, and Norman Barrett. Gastroenterology 1996;110:614-21. (Pubitemid 26043897)
4. Clark GW, Ireland AP, DeMeester TR. Dysplasia in Barrett's esophagus: diagnosis, surveillance and treatment. Dig Dis 1996;14: 213-27. (Pubitemid 126484432)
5. Marshall RE, Anggiansah A, Owen WJ. Bile in the oesophagus: clinical relevance and ambulatory detection. Br J Surg 1997;84:21-8. (Pubitemid 27033094)
6. Sharma P, Sampliner R. GERD, DGER, or both in Barrett's esophagus? Am J Gastroenterol 1997;92:903-4. (Pubitemid 27200821)
7. Stein HJ, Kauer WK, Feussner H, Siewert JR. Bile reflux in benign and malignant Barrett's esophagus: effect of medical acid suppression and Nissen fundoplication. J Gastrointest Surg 1998;2:333-41.
8. Owen WJ, Warren BF. The pathophysiology of Barrett's oesophagus. In: Watson A, Heading RC, Shepherd NA, editors. Barrett's oesophagus management guidelines. London: British Society of Gastroenterology; 2003 in press.
9. Coad RA, Shepherd NA. Barrett's oesophagus: definition, diagnosis and pathogenesis. Curr Diag Pathol 2003;9:218-27. (Pubitemid 36759395)
10. Wright NA. Migration of the ductular elements of gut-associated glands gives clues to the histogenesis of structures associated with responses to acid hypersecretory state: the origins of "gastric metaplasia" in the duodenum of the specialized mucosa of Barrett's esophagus and of pseudopyloric metaplasia. Yale J Biol Med 1996;69:147-53.
11. Skinner DB, Walther BC, Riddell RH, Schmidt H, Iascone C, DeMeester TR. Barrett's esophagus. Comparison of benign and malignant cases. Ann Surg 1983;198:554-65.
12. Spechler SJ. Short and ultrashort Barrett's esophagus - what does it mean? Semin Gastrointest Dis 1997;8:59-67. (Pubitemid 27196623)
13. Sharma P. Recent advances in Barrett's esophagus: short-segment Barrett's esophagus and cardia intestinal metaplasia. Semin Gastrointest Dis 1999;10:93-102. (Pubitemid 29340609)
14. Spechler SJ. The columnar-lined esophagus. History, terminology, and clinical issues. Gastroenterol Clin North Am 1997;26:455-66. (Pubitemid 27453227)
15. Watson A, Shepherd NA. The Definition of Barrett's oesophagus. In: Watson A, Heading RC, Shepherd NA, editors. Barrett's oesophagus management guidelines. London: British Society of Gastroenterology; 2003 in press.
16. Morales TG, Sampliner RE, Bhattacharyya A. Intestinal metaplasia of the gastric cardia. Am J Gastroenterol 1997;92:414-8. (Pubitemid 27108172)
17. Hackelsberger A, Gunther T, Schultze V, Manes G, Dominguez-Munoz JE, Roessner A et al. Intestinal metaplasia at the gastrooesophageal junction: Helicobacter pylori gastritis or gastrooesophageal reflux disease? Gut 1998;43:17-21. (Pubitemid 28335484)
18. Prach AT, MacDonald TA, Hopwood DA, Johnston DA. Increasing incidence of Barrett's oesophagus: education, enthusiasm, or epidemiology? Lancet 1997;350:933. (Pubitemid 27420536)
19. Cameron AJ. Epidemiology of columnar-lined esophagus and adenocarcinoma. Gastroenterol Clin North Am 1997;26:487-94. (Pubitemid 27453229)
20. Watson A. Barrett's oesophagus - 50 years on. Br J Surg 2000;87:529-31. (Pubitemid 30261084)
21. Shaheen NJ, Crosby MA, Bozymski EM, Sandler RS. Is there publication bias in the reporting of cancer risk in Barrett's esophagus? Gastroenterology 2000;119:333-8. (Pubitemid 30621983)
22. van der Burgh A, Dees J, Hop WC, van Blankenstein M. Oesophageal cancer is an uncommon cause of death in patients with Barrett's oesophagus. Gut 1996;39:5-8. (Pubitemid 26239094)
23. Anderson LA, Murray LJ, Murphy SJ, Fitzpatrick DA, Johnston BT, Watson RG, et al. Mortality in Barrett's oesophagus: results from a population-based study. Gut 2003;52:1081-4. (Pubitemid 36877416)
24. Heading RC. Barrett's oesophagus: epidemiology comes up with a surprise. Gut 2003;52:1079-80. (Pubitemid 36877415)
25. Tachimori Y. Clinical strategies for adenocarcinoma of the esophagus at the National Cancer Centre, Japan. In: Imamura M, editor. Superficial esophageal neoplasm: pathology, diagnosis and therapy. Tokyo: Springer; 2002. p. 66-74.
26. Lagergren J, Bergstrom R, Lindgren A, Nyren O. Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma. N Engl J Med 1999;340:825-31. (Pubitemid 29142625)
27. Blaser MJ. Helicobacter pylori and gastric diseases. BMJ 1998;316: 1507-10.
28. Hellier M, Shepherd NA. The diagnosis of Barrett's oesophagus. In: Watson A, Heading, RC, Shepherd NA, editors. Barrett's esophagus management guidelines. London: British Society of Gastroenterology; 2003 in press.
29. Nandurkar S, Talley NJ, Martin CJ, Ng TH, Adams S. Short segment Barrett's oesophagus: prevalence, diagnosis and associations. Gut 1997;40:710-5. (Pubitemid 27305461)
30. Sampliner RE, Sharma P. Short-segment Barrett's esophagus. J Clin Gastroenterol 1998;26:357-8.
31. Takubo K, Nixon JM, Jass JR. Ducts of esophageal glands proper and Paneth cells in Barrett's esophagus: frequency in biopsy specimens. Pathology 1995;27:315-7.
32. Paull A, Trier JS, Dalton MD, Camp RC, Loeb P, Goyal RK. The histologic spectrum of Barrett's esophagus. N Engl J Med 1976;295: 476-80.
33. Jass JR. Histopathology of early neoplasia in Barrett's esophagus. In: Imamura M, editor. Superficial esophageal neoplasm: pathology, diagnosis and therapy. Tokyo: Springer; 2002. p. 13-21.
34. Cameron AJ. Barrett's esophagus: prevalence and size of hiatal hernia. Am J Gastroenterol 1999;94:2054-9. (Pubitemid 29374531)
35. Spechler SJ. Barrett's esophagus. Semin Gastrointest Dis 1996;7: 51-60. (Pubitemid 26134943)
36. Riddell RH. The biopsy diagnosis of gastroesophageal reflux disease, "carditis," and Barrett's esophagus, and sequelae of therapy. Am J Surg Pathol 1996;20(Suppl 1):S31-S50.
37. Levine DS, Rubin CE, Reid BJ, Haggitt RC. Specialized metaplastic columnar epithelium in Barrett's esophagus. A comparative transmission electron microscopic study. Lab Invest 1989;60:418-32. (Pubitemid 19095959)
38. Kumble S, Omary MB, Fajardo LF, Triadafilopoulos G. Multifocal heterogeneity in villin and Ep-CAM expression in Barrett's esophagus. Int J Cancer 1996;66:48-54. (Pubitemid 26122321)
39. Griffel LH, Amenta PS, Das KM. Use of a novel monoclonal antibody in diagnosis of Barrett's esophagus. Dig Dis Sci 2000;45: 40-8. (Pubitemid 30111686)
40. Ormsby AH, Goldblum JR, Rice TW, Richter JE, Falk GW, Vaezi MF, et al. Cytokeratin subsets can reliably distinguish Barrett's esophagus from intestinal metaplasia of the stomach. Hum Pathol 1999;30:288-94. (Pubitemid 29125148)
41. Ormsby AH, Vaezi MF, Richter JE, Goldblum JR, Rice TW, Falk GW, et al. Cytokeratin immunoreactivity patterns in the diagnosis of short-segment Barrett's esophagus. Gastroenterology 2000;119: 683-90.
42. Couvelard A, Cauvin JM, Goldfain D, Rotenberg A, Robaszkiewicz M, Flejou JF. Cytokeratin immunoreactivity of intestinal metaplasia at normal oesophagogastric junction indicates its aetiology. Gut 2001;49:761-6. (Pubitemid 33096031)
43. El Zimaity HM, Graham DY. Cytokeratin subsets for distinguishing Barrett's esophagus from intestinal metaplasia in the cardia using endoscopic biopsy specimens. Am J Gastroenterol 2001;96:1378-82. (Pubitemid 32455062)
44. Glickman JN, Wang H, Das KM, Goyal RK, Spechler SJ, Antonioli D, et al. Phenotype of Barrett's esophagus and intestinal metaplasia of the distal esophagus and gastroesophageal junction: an immunohistochemical study of cytokeratins 7 and 20, Das-1 and 45 MI. Am J Surg Pathol 2001;25:87-94. (Pubitemid 32001837)
45. Ormsby AH, Goldblum JR, Rice TW, Richter JE, Gramlich TL. The utility of cytokeratin subsets in distinguishing Barrett's-related oesophageal adenocarcinoma from gastric adenocarcinoma. Histopathology 2001;38:307-11. (Pubitemid 34225024)
46. DeMeester SR, Wickramasinghe KS, Lord RV, Friedman A, Balaji NS, Chandrasoma PT, et al. Cytokeratin and DAS-1 immunostaining reveal similarities among cardiac mucosa, CIM, and Barrett's esophagus. Am J Gastroenterol 2002;97:2514-23.
47. Mohammed IA, Streutker CJ, Riddell RH. Utilization of cytokeratins 7 and 20 does not differentiate between Barrett's esophagus and gastric cardiac intestinal metaplasia. Mod Pathol 2002;15:611-6. (Pubitemid 34666464)
48. Odze R. Cytokeratin 7/20 immunostaining: Barrett's oesophagus or gastric intestinal metaplasia? Lancet 2002;359:1711-3. (Pubitemid 34607080)
49. Shen B, Ormsby AH, Shen C, Dumot JA, Shao YW, Bevins CL, et al. Cytokeratin expression patterns in noncardia, intestinal metaplasia- associated gastric adenocarcinoma: implication for the evaluation of intestinal metaplasia and tumors at the esophagogastric junction. Cancer 2002;94:820-31. (Pubitemid 34132313)
50. Goldblum JR. Ultra-short segment Barrett's oesophagus, carditis and intestinal metaplasia at the oesophago-gastric junction: pathology, causation and implications. Curr Diag Pathol 2003;9:228-34. (Pubitemid 36759396)
51. Wang HH, Doria MI Jr, Purohit-Buch S, Schnell T, Sontag S, Chejfec G. Barrett's esophagus. The cytology of dysplasia in comparison to benign and malignant lesions. Acta Cytologica 1992;36: 60-4.
52. Falk GW, Chittajallu R, Goldblum JR, Biscotti CV, Geisinger KR, Petras RE, et al. Surveillance of patients with Barrett's esophagus for dysplasia and cancer with balloon cytology. Gastroenterology 1997;112:1787-97. (Pubitemid 27240762)
53. Fennerty MB, Ditomasso J, Morales TG, Peterson D, Karmakar A, Fernandez T, et al. Screening for Barrett's esophagus by balloon cytology. Am J Gastroenterol 1995;90:1230-2.
54. Hardwick RH, Morgan RJ, Warren BF, Lott M, Alderson D. Brush cytology in the diagnosis of neoplasia in Barrett's esophagus. Dis Esophagus 1997;10:233-7. (Pubitemid 28039622)
55. Sampliner RE. Practice guidelines on the diagnosis, surveillance, and therapy of Barrett's esophagus. The Practice Parameters Committee of the American College of Gastroenterology. Am J Gastroenterol 1998;93:1028-32.
56. Weston AP, Badr AS, Hassanein RS. Prospective multivariate analysis of factors predictive of complete regression of Barrett's esophagus. Am J Gastroenterol 1999;94:3420-6.
57. Oberg S, Peters JH, DeMeester TR, Chandrasoma P, Hagen JA, Ireland AP, et al. Inflammation and specialized intestinal metaplasia of cardiac mucosa is a manifestation of gastroesophageal reflux disease. Ann Surg 1997;226:522-30.
58. Glickman JN, Fox V, Antonioli DA, Wang HH, Odze RD. Morphology of the cardia and significance of carditis in pediatric patients. Am J Surg Pathol 2002;26:1032-9. (Pubitemid 34810564)
59. De Hertogh G, Van Eyken P, Ectors N, Tack J, Geboes K. On the existence and location of cardiac mucosa: an autopsy study in embryos, fetuses, and infants. Gut 2003;52:791-6. (Pubitemid 36613483)
60. Sampliner RE. Updated guidelines for the diagnosis, surveillance, and therapy of Barrett's esophagus. Am J Gastroenterol 2002;97:1888-95.
61. Peters FT, Ganesh S, Kuipers EJ, Sluiter WJ, Klinkenberg-Knol EC, Lamers, et al. Endoscopic regression of Barrett's oesophagus during omeprazole treatment; a randomised double blind study. Gut 1999;45:489-94. (Pubitemid 29447813)
62. Shepherd NA. Barrett's oesophagus and proton pump inhibitors: a pathological perspective. Gut 2000;46:147-9. (Pubitemid 30305834)
63. Triadafilopoulos G. Proton pump inhibitors for Barrett's oesophagus. Gut 2000;46:144-6. (Pubitemid 30305833)
64. Gore S, Healey CJ, Sutton R, Eyre-Brook IA, Gear MW, Shepherd NA, et al. Regression of columnar lined (Barrett's) esophagus with continuous omeprazole therapy. Aliment Pharmacol Ther 1993;7:623-8. (Pubitemid 24035172)
65. Wilkinson SP, Biddlestone L, Gore S, Shepherd NA. Regression of columnar-lined (Barrett's) oesophagus with omeprazole 40mg daily: results of 5 years of continuous therapy. Aliment Pharmacol Ther 1999;13:1205-9. (Pubitemid 29445899)
66. Sampliner RE. Ablation of Barrett's mucosa. Gastroenterologist 1997;5:185-8. (Pubitemid 27400493)
67. Overholt BF. Results of photodynamic therapy in Barrett's esophagus: A review. Can J Gastroenterol 1999;13:393-6. (Pubitemid 29306770)
68. Barr H. The pathological implications of surveillance, treatment and surgery for Barrett's oesophagus. Curr Diag Pathol 2003;9:242-51. (Pubitemid 36759398)
69. Biddlestone LR, Barham CP, Wilkinson SP, Barr H, Shepherd NA. The histopathology of treated Barrett's esophagus: squamous re-epithelialization after acid suppression and laser and photodynamic therapy. Am J Surg Pathol 1998;22:239-45. (Pubitemid 28113386)
70. Sharma P, Morales TG, Bhattacharyya A, Garewal HS, Sampliner RE. Squamous islands in Barrett's esophagus: what lies underneath? Am J Gastroenterol 1998;93:332-5. (Pubitemid 29068331)
71. Riddell RH, Goldman H, Ransohoff DF, Appelman HD, Fenoglio CM, Haggitt RC, et al. Dysplasia in inflammatory bowel disease: standardized classification with provisional clinical applications. Hum Pathol 1983;14:931-68.
72. Reid BJ, Haggitt RC, Rubin CE, Roth G, Surawicz CM, Van Belle G, et al. Observer variation in the diagnosis of dysplasia in Barrett's esophagus. Hum Pathol 1988;19:166-78. (Pubitemid 18091022)
73. Schlemper RJ, Riddell RH, Kato Y, Borchard F, Cooper HS, Dawsey SM, et al. The Vienna classification of gastrointestinal epithelial neoplasia. Gut 2000;47:251-5. (Pubitemid 30489769)
74. Montgomery E, Bronner MP, Goldblum JR, Greenson JK, Haber MM, Hart J, et al. Reproducibility of the diagnosis of dysplasia in Barrett esophagus: a reaffirmation. Hum Pathol 2001;32:368-78. (Pubitemid 32378298)
75. Barr H, Shepherd NA. The management of dysplasia. In: Watson A, Heading RC, Shepherd NA, editors. Barrett's oesophagus management guidelines. London: British Society of Gastroenterology; 2003 in press.
76. Levine DS, Haggitt RC, Blount PL, Rabinovitch PS, Rusch VW, Reid BJ. An endoscopic biopsy protocol can differentiate highgrade dysplasia from early adenocarcinoma in Barrett's esophagus. Gastroenterology 1993;105:40-50. (Pubitemid 23234018)
77. Loft D, Alderson D. The surveillance of Barrett's oesophagus. In: Watson A, Heading RC, Shepherd NA, editors. Barrett's oesophagus management guidelines. London: British Society of Gastroenterology; 2003 in press.
78. Shepherd NA. Dysplasia in Barrett's oesophagus. Acta Endoscopica 2000;30:123-32. (Pubitemid 30214686)
79. Jankowski JA, Wright NA, Meltzer SJ, Triadafilopoulos G, Geboes K, Casson AG, et al. Molecular evolution of the metaplasia-dysplasia-adenocarcinoma sequence in the esophagus. Am J Pathol 1999;154:965-73. (Pubitemid 29169728)
80. Jankowski JA, Harrison RF, Perry I, Balkwill F, Tselepis C. Barrett's metaplasia. Lancet 2000;356:2079-85. (Pubitemid 32009828)
81. Biddlestone LR, Bailey TA, Whittles CE, Shepherd NA. The clinical and molecular pathology of Barrett's oesophagus. In: Kirkham N, Lemoine NR, editors. Progress in pathology, Vol 5. London: Greenwich Medical Media; 2001. p 57-80. (Pubitemid 33329865)
82. Scoazec JY. Tissue and cell imaging in situ: potential for applications in pathology and endoscopy. Gut 2003;52(Suppl 4):iv1-iv6.
83. Bruno MJ. Magnification endoscopy, high resolution endoscopy and chromoscopy: toward a better optical diagnosis. Gut 2003; 52(Suppl 4):iv7-iv11. (Pubitemid 36609698)
84. Van Dam J. Novel methods of enhanced endoscopic imaging. Gut 2003;52(Suppl 4):iv12-iv16. (Pubitemid 36609699)
85. Stone N, Kendall C, Shepherd N, Crow P, Barr H. Near-infrared Raman spectroscopy for the classification of epithelial pre-cancers and cancers. J Raman Spectroscopy 2002;33:564-73.
86. Kendall C, Stone N, Shepherd NA, Geboes K, Warren BF, Bennett R, et al. Raman spectroscopy, a potential tool for the objective identification and classification of neoplasia in Barrett's oesophagus. J Pathol 2003;200:602-9. (Pubitemid 36987309)
87. Cameron AJ, Zinsmeister AR, Ballard DJ, Carney JA. Prevalence of columnar-lined (Barrett's) esophagus. Comparison of population-based clinical and autopsy findings. Gastroenterology 1990;99:918-22. (Pubitemid 20338445)
88. Brown, CM, Jones R, Shirazi T, Codling BW, Valori RM. Prior diagnosis of Barrett's oesophagus is rare in patients with oesophageal carcinoma. Gut 1996;38:A23.