Utilization of cytokeratins 7 and 20 does not differentiate between Barrett’s esophagus and gastric cardiac intestinal metaplasia

Modern Pathology

Volumn 15, Issue 6, 2002, Pages 611-616

  Mohammed, I A ^a   Streutker, C J ^a,b   Riddell, R H ^a,c  

^a MCMASTER UNIVERSITY   (Canada)

^b ST MICHAEL'S HOSPITAL   (Canada)

^c MOUNT SINAI HOSPITAL   (Canada)

Author keywords

Barrett's esophagus; Cardiac intestinal metaplasia; Cytokeratin

Indexed keywords

CYTOKERATIN 20; CYTOKERATIN 7;

ADULT; AGED; ARTICLE; BARRETT ESOPHAGUS; CANCER RISK; CARDIA; CELL DIFFERENTIATION; COLUMNAR EPITHELIUM; EPITHELIUM CELL; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; INTESTINE METAPLASIA; LOWER ESOPHAGUS SPHINCTER; MAJOR CLINICAL STUDY; MALE; MALIGNANT TRANSFORMATION; PRIORITY JOURNAL; STOMACH BIOPSY; TUMOR LOCALIZATION; UTILIZATION REVIEW;

BARRETT ESOPHAGUS; CARDIA; DIAGNOSIS, DIFFERENTIAL; FEMALE; GASTROINTESTINAL DISEASES; HUMANS; IMMUNOHISTOCHEMISTRY; INTERMEDIATE FILAMENT PROTEINS; KERATIN-20; KERATIN-7; KERATINS; MALE; METAPLASIA; PREDICTIVE VALUE OF TESTS; SENSITIVITY AND SPECIFICITY;

EID: 0036082050     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: 10.1038/modpathol.3880574     Document Type: Article

References (32)

1. The histologic spectrum of Barrett's esophagus
2. Endoscopic biopsy can detect high-grade dysplasia or early adenocarcinoma in Barrett's esophagus without grossly recognizable neoplastic lesions
3. Adenocarcinoma and Barrett's esophagus. An overrated risk?
4. Scanning electron microscopy of Barrett's epithelium and its correlation with light microscopy and mucin stains
5. The relationship between columnar epithelial dysplasia and invasive adenocarcinoma arising in Barrett's esophagus
6. Dysplasia in Barrett's esophagus
7. Columnar mucosa and intestinal metaplasia of the esophagus: Fifty years of controversy
8. Gastroesophageal reflux disease and Barrett's esophagus
9. Effect of segment length on risk for neoplastic progression in patients with Barrett esophagus
10. Recent advances in Barrett's esophagus: Short-segment Barrett's esophagus and cardia intestinal metaplasia
11. The lower end of the esophagus
12. Histology of the gastroesophageal junction: An autopsy study
13. Definition of histopathologic changes in gastroesophageal reflux disease
14. Specialized intestinal metaplasia: Analysis of prevalence, risk factors and association with gastrooesophageal reflux disease
15. Characteristics of intestinal metaplasia in the gastric cardia
16. Inflammation and intestinal metaplasia of the gastric cardia: Helicobacter pylori, gastroesophageal reflux disease, or both
17. Cell damage and proliferation in human gastric mucosa infected by Helicobacter pylori-a comparison before and after H pylori eradication in non-atrophic gastritis
18. Effect of Helicobacter pylori infection, smoking and dietary habits on the occurrence of antrum intestinal metaplasia. Clinico-epidemiological study in Poland
19. The location and frequency of intestinal metaplasia at the esophagogastric junction in 223 consecutive autopsies: Implications for patient treatment and preventive strategies in Barrett's esophagus
20. Role of Helicobacter pylori gastritis in gastric atrophy, intestinal metaplasia, and gastric neoplasia
21. Gastric cardia inflammation and intestinal metaplasia: Association with reflux esophagitis and Helicobacter pylori
22. Relative risk of dysplasia for patients with intestinal metaplasia in the distal oesophagus and in the gastric cardia
23. The rising incidence of gastric cardia cancer
24. Adenocarcinoma of the esophagus and gastric cardia: Is there progress in the face of increasing cancer incidence?
25. Comparative study of intestinal metaplasia and mucin staining at the cardia and esophagogastric junction in 225 symptomatic patients presenting for diagnostic open-access gastroscopy
26. Significance of acid-mucin-positive non-goblet columnar cells in the distal esophagus and gastroesophageal junction
27. Mucin histochemistry in Barrett's esophagus
28. Cytokeratin immunoreactivity patterns in the diagnosis of short-segment Barrett's esophagus
29. Cytokeratin subsets can reliably distinguish Barrett's esophagus from intestinal metaplasia of the stomach
30. Cytokeratin 20 in human carcinomas. A new histodiagnostic marker detected by monoclonal antibodies
31. Use of monoclonal antibodies to keratin 7 in the differential diagnosis of adenocarcinomas
32. Phenotype of Barrett's esophagus and intestinal metaplasia of the distal esophagus and gastroesophageal junction: An immunohistochemical study of cytokeratins 7 and 20, Das-1 and 45 MI