Endocrine profiles and neuropsychologic correlates of functional hypothalamic amenorrhea in adolescents

Fertility and Sterility

Volumn 87, Issue 4, 2007, Pages 876-885

  Bomba, Monica ^a   Gambera, Alessandro ^a   Bonini, Luisa ^a   Peroni, Maria ^a   Neri, Francesca ^a   Scagliola, Pasquale ^a   Nacinovich, Renata ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

Author keywords

adolescence; depressive traits; eating disorders; Functional hypothalamic amenorrhea; hormone profile; life events; psychosomatic disorders; trigger factors

Indexed keywords

ANDROGEN; ESTROGEN; GONADOTROPIN; HYDROCORTISONE; INSULIN; LEPTIN; PROLACTIN; SOMATOMEDIN BINDING PROTEIN 1; SOMATOMEDIN C; THYROID HORMONE;

ADOLESCENT; AMENORRHEA; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DEPRESSION; EATING DISORDER; FEMALE; FUNCTIONAL HYPOTHALAMIC AMENORRHEA; HUMAN; HYPOTHALAMUS; METABOLIC PARAMETERS; NEUROPSYCHOLOGY; PRIORITY JOURNAL; PSYCHOSOMATIC DISORDER; SEMI STRUCTURED INTERVIEW;

ADOLESCENT; AMENORRHEA; ANXIETY; BODY MASS INDEX; CROSS-SECTIONAL STUDIES; DEPRESSION; EATING DISORDERS; FEMALE; GONADAL STEROID HORMONES; GONADOTROPINS; HORMONES; HUMANS; HYDROCORTISONE; HYPOTHALAMIC DISEASES; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1; LEPTIN; PSYCHOPHYSIOLOGIC DISORDERS; SEX HORMONE-BINDING GLOBULIN; STRESS, PSYCHOLOGICAL;

EID: 34047271039     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2006.09.011     Document Type: Article

References (45)

1. Biller B.M.K., Federoff H.J., Koenig J.I., and Klibansky A. Abnormal cortisol secretion and responses to corticotropin-releasing hormone in women with hypothalamic amenorrhea. J Clin Endocrinol Metab 70 (1990) 311-317
2. Perkins R.B., Hall J.E., and Martin K.A. Neuroendocrine abnormalities in hypothalamic amenorrhea: spectrum, stability and response to neurotransmitter modulation. J Clin Endocrinol Metab 84 (1999) 1905-1911
3. Genazzani A.D., Gastaldi M., Volpe A., Petraglia F., and Genazzani A.R. Spontaneous episodic release of adenohypophyseal hormones in hypothalamic amenorrhea. Gynecol Endocrinol 9 (1995) 325-334
4. Speroff L., Glass R., and Kase N. Clinical gynecologic endocrinology and infertility. 6th ed. (1999), Lippincott Williams and Wilkins, Baltimore
5. Falsetti L., Pasinetti E., Mazzani M.D., and Gastaldi A. Weight loss and menstrual cycle: clinical and endocrinological evaluation. Gynecol Endocrinol 6 (1992) 49-56
6. Couzinet B., Young J., Braily S., Le Bouc Y., Chanson P., and Schaison G. Functional hypothalamic amenorrhea: a partial and reversible gonadotropin deficiency of nutritional origin. Clin Endocrinol 50 (1999) 229-235
7. Marcus M.D., Loucks T.L., and Berga S.L. Psychological correlates of functional hypothalamic amenorrhea. Fertil Steril 76 (2001) 310-316
8. Kondoh Y., Uemura T., Murase M., Yokoi N., Ishikawa M., and Hirahara F. A longitudinal study of disturbances of the hypothalamic-pituitary-adrenal axis in women with progestin-negative functional hypothalamic amenorrhea. Fertil Steril 76 (2001) 748-752
9. Gambacciani M., Yen S.S.C., and Rasmussen D.D. GnRH release from the mediobasal hypothalamus: in vitro inhibition by corticotropin-releasing factor. Neuroendocrinology 43 (1986) 533-536
10. Petraglia F., Sutton S., Vale W., and Plotsky P. Corticotropin-releasing factor decreases plasma luteinizing hormone levels in female rats by inhibiting gonadotropin-releasing-hormone release into hypophyseal-portal circulation. Endocrinol 120 (1987) 1083-1088
11. Meaney M.J. Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations. Annu Rev Neurosci 24 (2001) 1161-1192
12. Wauters M., Considine R.V., and Van Gaal E.B. Human leptin from an adipocyte hormone to an endocrine mediator. Eur J Endocrinol 143 (2000) 293-311
13. Andrico S., Gambera A., Specchia C., Pellegrini C., Falsetti L., and Sartori E. Leptin in functional hypothalamic amenorrhea. Hum Reprod 17 (2002) 2043-2048
14. Miller K.K., Parulekar M.S., Schoenfeld E., Anderson E., Hubbard J., Klibansky A., et al. Decreased leptin levels in normal weight women with hypothalamic amenorrhea: the effects of body composition and nutritional intake. J Clin Endocrinol Metab 83 (1998) 2309-2312
15. Kalra S.P., and Kalra P.S. Nutritional infertility: the role of the interconnected hypothalamic neuropeptide Y-galanin-opioid network. Front Neuroendocrinol 17 (1996) 371-401
16. Berga S.L., Louks A.B., Rossmanith W.G., Kettel L.M., Laughlin G.A., and Yen S.S. Acceleration of luteinizing hormone pulse frequency in functional hypothalamic amenorrhea by dopaminergic blockade. J Clin Endocrinol Metab 45 (1991) 743-750
17. Kadva A., Djahanbakhch O., Monson J., Di W.L., and Silman R. Elevated nocturnal melatonin is a consequence of gonadotropin-releasing hormone deficiency in women with hypothalamic amenorrhea. J Clin Endocrinol Metab 83 10 (1998) 3653-3662
18. Conover C.A., Divertie G.D., and Lee P.D.K. Cortisol increases plasma insulin-like growth factor binding protein-1 in humans. Acta Endocrinol 128 (1993) 140-143
19. Laughlin G.A., Dominguez C.E., and Yen S.S.C. Nutritional and endocrine-metabolic aberrations in women with functional hypothalamic amenorrhea. J Clin Endocrinol Metab 83 (1998) 25-32
20. Reifenstein Jr. E.C. Psychogenic or "hypothalamic" amenorrhea. Med Clin North Am 30 (1946) 1103-1115
21. Russel G. Premenstrual tension and "psychogenic" amenorrhea: psychophysical interaction. J Psychosom Res 16 (1972) 279-287
22. Fioroni L., Fava M., Genazzani A.D., Facchinetti F., and Genazzani A.R. Life events impact in patients with secondary amenorrhea. J Psychosom Research 38 (1994) 617-622
23. Nappi R.E., and Facchinetti F. Psychoneuroendocrine correlates of secondary amenorrhea. Arch Women Ment Health 6 (2003) 83-89
24. Nappi R.E., Neri I., Veneroni F., Polatti F., Piccinini F., and Facchinetti F. Pituitary LH reserve suggests high risk of bulimia in amenorrheic women. Psychoneuroendocrinology 26 (2001) 721-730
25. Kaufman J., Plotsky P.M., Nemeroff C.B., and Charney D.S. Effects of early adverse experiences on brain structure and function: clinical implication. Biol Psychiatry 48 (2000) 778-790
26. Levine S. Influence of psychological variables on the activity of the hypothalamic-pituitary-adrenal axis. Eur J Pharmacol 48 (2000) 149-160
27. Cicchetti D. The impact of social experience on neurobiological systems: illustration from a constructivist view of child maltreatment. Cogn Dev 17 (2002) 1407-1428
28. Cicchetti D., and Rogosch F.A. A developmental psychopathology perspective on adolescence. J Consult Clin Psychol 70 (2002) 6-20
29. Spear L.P. The adolescent brain and age-related behavioral manifestations. Neurosci Behav Res 24 (2000) 417-463
30. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed. (1994), American Psychiatric Association, Washington, DC
31. Kovacs M. The Children's Depression Inventory. Psychopharmacol Bull 21 (1985) 995-998
32. Garner D.M., Olmsted M.P., and Polivy J. Development and validation of a multidimensional eating disorder inventory for anorexia nervosa and bulimia. Int J Eat Disord 2 (1983) 15-34
33. Tietze K. Zur genese und prognose der notstandsamenorrhoe. Zbl Gynakol (1948) 370-377
34. Nappi R.E., Neri I., Veneroni F., Polatti F., Piccinini F., and Facchinetti F. Pituitary LH reserve suggests high risk of bulimia in amenorrheic women. Psychoneuroendocrinology 26 (2001) 721-730
35. Verri A., Nappi R.E., Cecchini A.P., Vallero E., Luzi S., and Zara C. Eating disorders and axis I psychiatric co-morbidity in amenorrheic women. Int J Eat Disord 24 (1998) 137-146
36. Matzen L.E., and Kvetny J. The influence of caloric deprivation and food composition on TSH, thyroid hormones and nuclear binding of T3 in molecular blood cells in obese women. Metabolism 38 (1989) 555-562
37. Lim C.F., Bai Y., Toplisn D.J., Barlow J.W., and Stockigt J.R. Drug and fatty acid effects on serum thyroid hormone binding. J Clin Endocrinol 67 (1988) 682-688
38. Legradi G., Emerson C.H., Ahima R.S., Flier J.S., and Lechan R.M. Leptin prevents fasting-induced suppression of prothyrotropin-releasing hormone messenger ribonucleic acid in neurons of the hypothalamic paraventricular nucleus. Endocrinol 138 (1997) 2569-2575
39. Dyer C.J., Simmons J.M., Matteri R.L., and Keisler D.H. Leptin receptor mRNA is expressed in ewe anterior pituitary and adipose tissue and is differentially expressed in hypothalamic regions of well-fed and feed-restricted ewes. Dom Anim Endocr 14 (1997) 119-128
40. Peters F., Richter D., and Breckwoldt M. Interactions between psychosomatic conflicts and gonadotropin secretion. Acta Obstet Gynecol Scand 61 (1982) 439-443
41. Moles A., Rizzi R., and D'Amato F.R. Postnatal stress in mice: does "stressing" the mother have the same effect as "stressing" the pups?. Dev Psychobiol 44 (2004) 230-237
42. Diego M.A., Field T., Hernandez-Reif M., Cullen C., Schanberg S., and Kuhn C. Prepartum, postpartum and chronic depression effects on newborns. Psychiatry 67 (2004) 63-80
43. Koob G.F., Heinrichs S.C., Menzaghi F., Pich E.M., and Britton K.T. Corticotropin-releasing factor, stress and behaviour. Semin Neurosci 6 (1994) 221-229
44. Nemeroff C.B. The corticotropin-releasing factor (CRF) hypothesis of depression: new findings and new directions. Mol Psychiatr 1 (1996) 336-342
45. Brindley D.N., and Rolland Y. Possible connections between stress, diabetes, obesity, hypertension and altered lipoprotein metabolism that may result in atherosclerosis. Clin Sci 77 (1989) 453-461