A web tool for the identification of potential interactive effects of chemical mixtures

Journal of Occupational and Environmental Hygiene

Volumn 4, Issue 4, 2007, Pages 281-287

  Vyskocil, Adolf ^a   Drolet, Daniel ^b   Viau, Claude ^a   Lemay, Francois ^b   Lapointe, Gilles ^c   Tardif, Robert ^a   Truchon, Ginette ^b   Baril, Marc ^b   Gagnon, Normand ^c   Gagnon, France ^a   Bégin, Denis ^a   Gérin, Michel ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b INSTITUT DE RECHERCHE ROBERT SAUVÉ EN SANTÉ ET EN SÉCURITÉ DU TRAVAIL   (Canada)

^c Le Service du Répertoire Toxicologique   (Canada)

Author keywords

Chemical mixtures; Database; Interactions; Occupational atmospheres

Indexed keywords

AIR POLLUTANT; ANIMAL; ARTICLE; DOCUMENTATION; DRUG MIXTURE; DRUG POTENTIATION; FACTUAL DATABASE; HUMAN; INTERNET; OCCUPATIONAL EXPOSURE; UTILIZATION REVIEW;

AIR POLLUTANTS, OCCUPATIONAL; ANIMALS; COMPLEX MIXTURES; DATABASES, FACTUAL; DOCUMENTATION; DRUG SYNERGISM; HUMANS; INTERNET; OCCUPATIONAL EXPOSURE;

EID: 34047261776     PISSN: 15459624     EISSN: 15459632     Source Type: Journal    
DOI: 10.1080/15459620701225103     Document Type: Article

References (22)

1. Burgess, W.A.: Recognition of Health Hazards in Industry. A Review of Materials and Processes. New York: John Wiley & Sons, 1995. pp. 938.
2. National Institute for Occupational Safety and Health (NIOSH): Mixed Exposures Research Agenda Report by the NORA Mixed Exposures Team (No. 2005-106). Cincinnati, Ohio: NIOSH, 2004.
3. Feron, V.J., F.R. Cassee, J.P. Groten, P.W. van Vliet, and J.A. van Zorge: International issues on human health effects of exposure to chemical mixtures. Environ. Health Perspect. 110(Suppl. 6):893-898 (2002).
4. U.S. Environmental Protection Agency (USEPA): Supplementary Guidance for Conducting Health Risk Assessment of Chemical Mixtures, Risk Assessment Forum (EPA/630/R-00/002).Washington, D.C.: USEPA, 2000.
5. Wilbur, S., H. Hansen, H. Pohl, J. Colman, andW. Stiteler: Guidance Manual for the Assessment of Joint Toxic Action of Chemical Mixtures. Atlanta.: Agency for Toxic Substances and Disease Registry (ATSDR), U.S. Department of Health and Human Services, Public Health Service, 2004.
6. Yang, R.S.H.: Toxicology of Chemical Mixtures: Case studies, Mechanisms and Novel Approaches. San Diego, Calif.: Academic Press, 1994. pp. xxi-xxiii.
7. Gouvernement du Québec: Regulation respecting occupational health and safety. Gazette officielle du Québec Part 2 133(29):3888-3994 (2001).
8. American Conference of Governmental Industrial Hygienists (ACGIH): Documentation of the TLVs and BEIs with Other Worldwide Occupational Exposure Values, CD ROM. Cincinnati, Ohio: ACGIH, 2003.
9. Vyskocil, A., D. Drolet, C. Viau, J. Brodeur, R. Tardif, M. Gérin, et al.: Database for the toxicological evaluation of mixtures in occupational atmospheres. Environ. Toxicol. Pharmacol. 18:235-242 (2004).
10. U.S. Environmental Protection Agency (USEPA): Toxicologic Interaction Data Base (MIXTOX), version 1.5.Washington, D.C.: USEPA, 1992.
11. Cambridge Scientific Abstracts in cooperation with the International Food Information Service and the U.S. National Library of Medicine: Poltox. I [CD-ROM]. Norwood: SilverPlatter Information, 2001.
12. "Toxline." [Online] Available at http://toxnet.nlm.nih.gov/cgi- bin/sis/htmlgen?TOXLINE (Accessed February 21, 2006).
13. Service du répertoire toxicologique of the Commission de la santé et de la sécurité du travail (CSST): Databases on chemical or biological products from the CSST toxicological repertory. [Online in French with English instructions] Available at http://www.reptox.csst.qc.ca/ ToEnglishUsers.htm (Accessed February 21, 2006).
14. Sieber, K., J. Seta, and R.A. Young: A job exposure matrix for identification of potential exposures in occupational settings. InBook of Abstracts of the 9th International Symposium: Epidemiology in Occupational Health, September 23-24, 1992. Cincinnati, Ohio: National Institute for Occupational Safety and Health and University of Cincinnati, 1992. p. 259.
15. Seta, J.A., D.S. Sundin, and D.H. Pedersen: National Occupational Exposure Survey Field Guidelines (Pub. No. 88-106) Cincinnati, Ohio: National Institute for Occupational Safety and Health, 1988.
16. Austin, G.T.: Shreve's Chemical Process Industries. NewYork: McGraw-Hill Book Company, 1984.
17. Budavari, S.: The Merck Index. Whitehouse Station, N.J.: Merck & Co. Inc., 1996.
18. Kroschwitz, J.I. (ed.): Kirk-Othmer Concise Encyclopedia of Chemical Technology, 4th Ed. New York: John Wiley & Sons, 1999.
19. Agency for Toxic Substances and Disease Registry (ATSDR): "Agency for Toxic Substances&Disease Registry Toxicological Profiles" [Online] Available at http://www.atsdr.cdc.gov/toxprofiles (Accessed February 21, 2006).
20. National Library of Medicine (NLM) and National Institutes of Health (NIH): "Hazardous Substances Data Bank" [Online] Available at http://toxnet.nlm.nih.gov (Accessed February 21, 2006).
21. IRSST: "Mixtures of substances in the workplace: Utility for evaluating the chemical risk"[Online] Available at http://www.irsst.qc.ca/ en/ outil 100037.html (Accessed February 21, 2006).
22. American Conference of Governmental Industrial Hygienists (ACGIH): TLVs and BEIs Based on the Documentation of the Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices. Cincinnati, Ohio: ACGIH, 2005.