메뉴 건너뛰기




Volumn 81, Issue , 2007, Pages 59-84

An in vitro model of Stroke-Induced Epilepsy: Elucidation of The roles of Glutamate and Calcium in The induction and Maintenance of Stroke-Induced Epileptogenesis

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; GLUTAMIC ACID;

EID: 34047237833     PISSN: 00747742     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0074-7742(06)81005-6     Document Type: Review
Times cited : (41)

References (65)
  • 1
    • 0023037947 scopus 로고
    • Magnesium-free medium activates seizure-like events in the rat hippocampal slice
    • Anderson W.W., Lewis D.V., Swartzwelder H.S., and Wilson W.A. Magnesium-free medium activates seizure-like events in the rat hippocampal slice. Brain Res. 398 (1986) 215-219
    • (1986) Brain Res. , vol.398 , pp. 215-219
    • Anderson, W.W.1    Lewis, D.V.2    Swartzwelder, H.S.3    Wilson, W.A.4
  • 2
    • 0032874376 scopus 로고    scopus 로고
    • Nuclear calcium-activated gene expression: Possible roles in neuronal plasticity and epileptogenesis
    • Bading H. Nuclear calcium-activated gene expression: Possible roles in neuronal plasticity and epileptogenesis. Epilepsy Res. 36 (1999) 225-231
    • (1999) Epilepsy Res. , vol.36 , pp. 225-231
    • Bading, H.1
  • 3
    • 0032127595 scopus 로고    scopus 로고
    • Neuronal calcium signaling
    • Berridge M.J. Neuronal calcium signaling. Neuron 21 (1998) 13-26
    • (1998) Neuron , vol.21 , pp. 13-26
    • Berridge, M.J.1
  • 4
    • 0033398705 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase II activity in a hippocampal neuronal culture model of spontaneous recurrent seizures
    • 2+/calmodulin-dependent protein kinase II activity in a hippocampal neuronal culture model of spontaneous recurrent seizures. Brain Res. 851 (1999) 54-65
    • (1999) Brain Res. , vol.851 , pp. 54-65
    • Blair, R.E.1    Churn, S.B.2    Sombati, S.3    Lou, J.K.4    DeLorenzo, R.J.5
  • 6
    • 0028806656 scopus 로고
    • Massive persistent release of excitatory amino acids following human occlusive stroke
    • Bullock R., Zauner A., Woodward J., and Young H.F. Massive persistent release of excitatory amino acids following human occlusive stroke. Stroke 26 (1995) 2187-2189
    • (1995) Stroke , vol.26 , pp. 2187-2189
    • Bullock, R.1    Zauner, A.2    Woodward, J.3    Young, H.F.4
  • 7
    • 0031264010 scopus 로고    scopus 로고
    • Calcium signalling in the cell nucleus
    • Carafoli E., Nicotera P., and Santella L. Calcium signalling in the cell nucleus. Cell Calcium 22 (1997) 313-319
    • (1997) Cell Calcium , vol.22 , pp. 313-319
    • Carafoli, E.1    Nicotera, P.2    Santella, L.3
  • 8
  • 9
    • 0028016077 scopus 로고
    • Glutamate receptors and the induction of excitotoxic neuronal death
    • Choi D.W. Glutamate receptors and the induction of excitotoxic neuronal death. Prog. Brain Res. 100 (1994) 47-51
    • (1994) Prog. Brain Res. , vol.100 , pp. 47-51
    • Choi, D.W.1
  • 10
    • 0025934773 scopus 로고
    • Exposure of hippocampal slices to magnesium-free medium produces epileptiform activity and simultaneously decreases calcium and calmodulin-dependent protein kinase II activity
    • Churn S.B., Anderson W.W., and DeLorenzo R.J. Exposure of hippocampal slices to magnesium-free medium produces epileptiform activity and simultaneously decreases calcium and calmodulin-dependent protein kinase II activity. Epilepsy Res. 9 (1991) 211-217
    • (1991) Epilepsy Res. , vol.9 , pp. 211-217
    • Churn, S.B.1    Anderson, W.W.2    DeLorenzo, R.J.3
  • 11
    • 0034284705 scopus 로고    scopus 로고
    • Chronic inhibition of Ca(2+)/calmodulin kinase II activity in the pilocarpine model of epilepsy
    • Churn S.B., Kochan L.D., and DeLorenzo R.J. Chronic inhibition of Ca(2+)/calmodulin kinase II activity in the pilocarpine model of epilepsy. Brain Res. 875 (2000) 66-77
    • (2000) Brain Res. , vol.875 , pp. 66-77
    • Churn, S.B.1    Kochan, L.D.2    DeLorenzo, R.J.3
  • 12
    • 0030995878 scopus 로고    scopus 로고
    • Pharmacology and functions of metabotropic glutamate receptors
    • Conn P.J., and Pin J.P. Pharmacology and functions of metabotropic glutamate receptors. Annu. Rev. Pharmacol. Toxicol. 37 (1997) 205-237
    • (1997) Annu. Rev. Pharmacol. Toxicol. , vol.37 , pp. 205-237
    • Conn, P.J.1    Pin, J.P.2
  • 13
    • 0025101588 scopus 로고
    • NMDA receptor blockade inhibits glutamate-induced kindling of the rat amygdala
    • Croucher M.J., and Bradford H.F. NMDA receptor blockade inhibits glutamate-induced kindling of the rat amygdala. Brain Res. 506 (1990) 349-352
    • (1990) Brain Res. , vol.506 , pp. 349-352
    • Croucher, M.J.1    Bradford, H.F.2
  • 14
    • 0023773259 scopus 로고
    • Inhibition of the development of electrical kindling of the prepyriform cortex by daily focal injections of excitatory amino acid antagonists
    • Croucher M.J., Bradford H.F., Sunter D.C., and Watkins J.C. Inhibition of the development of electrical kindling of the prepyriform cortex by daily focal injections of excitatory amino acid antagonists. Eur. J. Pharmacol. 152 (1988) 29-38
    • (1988) Eur. J. Pharmacol. , vol.152 , pp. 29-38
    • Croucher, M.J.1    Bradford, H.F.2    Sunter, D.C.3    Watkins, J.C.4
  • 15
    • 0342981455 scopus 로고    scopus 로고
    • Duration of glutamate release after acute ischemic stroke
    • Davalos A., Castillo J., Serena J., and Noya M. Duration of glutamate release after acute ischemic stroke. Stroke 28 (1997) 708-710
    • (1997) Stroke , vol.28 , pp. 708-710
    • Davalos, A.1    Castillo, J.2    Serena, J.3    Noya, M.4
  • 16
    • 0020059117 scopus 로고
    • Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord
    • Davies J., and Watkins J.C. Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord. Brain Res. 235 (1982) 378-386
    • (1982) Brain Res. , vol.235 , pp. 378-386
    • Davies, J.1    Watkins, J.C.2
  • 17
    • 0032612744 scopus 로고    scopus 로고
    • Symptomatic lesional epilepsies: Introduction
    • Delgado-Escueta A.V., and Porter R. Symptomatic lesional epilepsies: Introduction. Adv. Neurol. 79 (1999) 433-435
    • (1999) Adv. Neurol. , vol.79 , pp. 433-435
    • Delgado-Escueta, A.V.1    Porter, R.2
  • 18
    • 0032962717 scopus 로고    scopus 로고
    • Long-term modulation of gene expression in epilepsy
    • DeLorenzo R.J., and Morris T.A. Long-term modulation of gene expression in epilepsy. Neuroscientist 5 (1999) 86-99
    • (1999) Neuroscientist , vol.5 , pp. 86-99
    • DeLorenzo, R.J.1    Morris, T.A.2
  • 19
    • 0032564334 scopus 로고    scopus 로고
    • 2+ transduction pathway causes spontaneous recurrent epileptiform discharges in hippocampal neurons in culture
    • 2+ transduction pathway causes spontaneous recurrent epileptiform discharges in hippocampal neurons in culture. Proc. Natl. Acad. Sci. USA 95 (1998) 14482-14487
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 14482-14487
    • DeLorenzo, R.J.1    Pal, S.2    Sombati, S.3
  • 20
    • 14544282458 scopus 로고    scopus 로고
    • Cellular mechanisms underlying acquired epilepsy: The calcium hypothesis of the induction and maintainance of epilepsy
    • DeLorenzo R.J., Sun D.A., and Deshpande L.S. Cellular mechanisms underlying acquired epilepsy: The calcium hypothesis of the induction and maintainance of epilepsy. Pharmacol. Ther. 105 (2005) 229-266
    • (2005) Pharmacol. Ther. , vol.105 , pp. 229-266
    • DeLorenzo, R.J.1    Sun, D.A.2    Deshpande, L.S.3
  • 21
    • 0025025696 scopus 로고
    • Rapid, sensitive, and simple method for quantification of both neurotoxic and neurotrophic effects of NMDA on cultured cerebellar granule cells
    • Didier M., Heaulme M., Soubrie P., Bockaert J., and Pin J.P. Rapid, sensitive, and simple method for quantification of both neurotoxic and neurotrophic effects of NMDA on cultured cerebellar granule cells. J. Neurosci. Res. 27 (1990) 25-35
    • (1990) J. Neurosci. Res. , vol.27 , pp. 25-35
    • Didier, M.1    Heaulme, M.2    Soubrie, P.3    Bockaert, J.4    Pin, J.P.5
  • 24
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischaemic stroke: An integrated view
    • Dirnagl U., Iadecola C., and Moskowitz M.A. Pathobiology of ischaemic stroke: An integrated view. Trends Neurosci. 22 (1999) 391-397
    • (1999) Trends Neurosci. , vol.22 , pp. 391-397
    • Dirnagl, U.1    Iadecola, C.2    Moskowitz, M.A.3
  • 25
    • 0024711693 scopus 로고
    • Seizure-like activity and cellular damage in rat hippocampal neurons in cell culture
    • Furshpan E.J., and Potter D.D. Seizure-like activity and cellular damage in rat hippocampal neurons in cell culture. Neuron 3 (1989) 199-207
    • (1989) Neuron , vol.3 , pp. 199-207
    • Furshpan, E.J.1    Potter, D.D.2
  • 26
    • 0028987937 scopus 로고
    • Calcium signaling in neurons: Molecular mechanisms and cellular consequences
    • Ghosh A., and Greenberg M.E. Calcium signaling in neurons: Molecular mechanisms and cellular consequences. Science 268 (1995) 239-247
    • (1995) Science , vol.268 , pp. 239-247
    • Ghosh, A.1    Greenberg, M.E.2
  • 27
  • 28
    • 0024150253 scopus 로고
    • Brain ion homeostasis in cerebral ischemia
    • Hansen A.J., and Nedergaard M. Brain ion homeostasis in cerebral ischemia. Neurochem. Pathol. 9 (1988) 195-209
    • (1988) Neurochem. Pathol. , vol.9 , pp. 195-209
    • Hansen, A.J.1    Nedergaard, M.2
  • 29
    • 0031019855 scopus 로고    scopus 로고
    • Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression
    • Hardingham G.E., Chawla S., Johnson C.M., and Bading H. Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression. Nature 385 (1997) 260-265
    • (1997) Nature , vol.385 , pp. 260-265
    • Hardingham, G.E.1    Chawla, S.2    Johnson, C.M.3    Bading, H.4
  • 31
    • 0025954532 scopus 로고
    • Prevalence of epilepsy in Rochester, Minnesota: 1940-1980
    • Hauser W.A., Annegers J.F., and Kurland L.T. Prevalence of epilepsy in Rochester, Minnesota: 1940-1980. Epilepsia 32 (1991) 429-445
    • (1991) Epilepsia , vol.32 , pp. 429-445
    • Hauser, W.A.1    Annegers, J.F.2    Kurland, L.T.3
  • 32
    • 0033822534 scopus 로고    scopus 로고
    • Synaptic activity-dependent developmental regulation of NMDA receptor subunit expression in cultured neocortical neurons
    • Hoffmann H., Gremme T., Hatt H., and Gottmann K. Synaptic activity-dependent developmental regulation of NMDA receptor subunit expression in cultured neocortical neurons. J. Neurochem. 75 (2000) 1590-1599
    • (2000) J. Neurochem. , vol.75 , pp. 1590-1599
    • Hoffmann, H.1    Gremme, T.2    Hatt, H.3    Gottmann, K.4
  • 34
    • 0027982679 scopus 로고
    • Viability thresholds and the penumbra of focal ischemia
    • Hossmann K.A. Viability thresholds and the penumbra of focal ischemia. Ann. Neurol. 36 (1994) 557-565
    • (1994) Ann. Neurol. , vol.36 , pp. 557-565
    • Hossmann, K.A.1
  • 35
    • 0034055456 scopus 로고    scopus 로고
    • Ionic selectivity of low-affinity ratiometric calcium indicators: mag-Fura-2, Fura-2FF and BTC
    • Hyrc K.L., Bownik J.M., and Goldberg M.P. Ionic selectivity of low-affinity ratiometric calcium indicators: mag-Fura-2, Fura-2FF and BTC. Cell Calcium 27 (2000) 75-86
    • (2000) Cell Calcium , vol.27 , pp. 75-86
    • Hyrc, K.L.1    Bownik, J.M.2    Goldberg, M.P.3
  • 36
    • 0025579845 scopus 로고
    • Seizure-like activity and glutamate receptors in hippocampal neurons in culture
    • Koroshetz W.J., and Furshpan E.J. Seizure-like activity and glutamate receptors in hippocampal neurons in culture. Neurosci. Res. Suppl. 13 (1990) S65-S74
    • (1990) Neurosci. Res. Suppl. , vol.13
    • Koroshetz, W.J.1    Furshpan, E.J.2
  • 37
    • 0029117733 scopus 로고
    • Inability to restore resting intracellular calcium levels as an early indicator of delayed neuronal cell death
    • Limbrick Jr. D.D., Churn S.B., Sombati S., and DeLorenzo R.J. Inability to restore resting intracellular calcium levels as an early indicator of delayed neuronal cell death. Brain Res. 690 (1995) 145-156
    • (1995) Brain Res. , vol.690 , pp. 145-156
    • Limbrick Jr., D.D.1    Churn, S.B.2    Sombati, S.3    DeLorenzo, R.J.4
  • 38
    • 0032845121 scopus 로고    scopus 로고
    • Ischemic cell death in brain neurons
    • Lipton P. Ischemic cell death in brain neurons. Physiol. Rev. 79 (1999) 1431-1568
    • (1999) Physiol. Rev. , vol.79 , pp. 1431-1568
    • Lipton, P.1
  • 39
    • 8444232772 scopus 로고    scopus 로고
    • New horizons in the development of antiepileptic drugs: The search for new targets
    • Loscher W., and Schmidt D. New horizons in the development of antiepileptic drugs: The search for new targets. Epilepsy Res. 60 (2004) 77-159
    • (2004) Epilepsy Res. , vol.60 , pp. 77-159
    • Loscher, W.1    Schmidt, D.2
  • 40
    • 0027249095 scopus 로고
    • Antiepileptic drug mechanisms of action
    • Macdonald R.L., and Kelly K.M. Antiepileptic drug mechanisms of action. Epilepsia 34 Suppl. 5 (1993) S1-S8
    • (1993) Epilepsia , vol.34 , Issue.SUPPL. 5
    • Macdonald, R.L.1    Kelly, K.M.2
  • 41
    • 0000253091 scopus 로고
    • Cortical cellular phenomena in experimental epilepsy: Interictal manifestations
    • Matsumoto H., and Marsan C.A. Cortical cellular phenomena in experimental epilepsy: Interictal manifestations. Exp. Neurol. 9 (1964) 286-304
    • (1964) Exp. Neurol. , vol.9 , pp. 286-304
    • Matsumoto, H.1    Marsan, C.A.2
  • 42
    • 0023492484 scopus 로고
    • Permeation and block of N-methyl-D-aspartic acid receptor channels by divalent cations in mouse cultured central neurones
    • Mayer M.L., and Westbrook G.L. Permeation and block of N-methyl-D-aspartic acid receptor channels by divalent cations in mouse cultured central neurones. J. Physiol. 394 (1987) 501-527
    • (1987) J. Physiol. , vol.394 , pp. 501-527
    • Mayer, M.L.1    Westbrook, G.L.2
  • 43
    • 0033216154 scopus 로고    scopus 로고
    • Persistent increased DNA-binding and expression of serum response factor occur with epilepsy-associated long-term plasticity changes
    • Morris T.A., Jafari N., Rice A.C., Vasconcelos O., and DeLorenzo R.J. Persistent increased DNA-binding and expression of serum response factor occur with epilepsy-associated long-term plasticity changes. J. Neurosci. 19 (1999) 8234-8243
    • (1999) J. Neurosci. , vol.19 , pp. 8234-8243
    • Morris, T.A.1    Jafari, N.2    Rice, A.C.3    Vasconcelos, O.4    DeLorenzo, R.J.5
  • 44
    • 0034705573 scopus 로고    scopus 로고
    • Chronic DeltaFosB expression and increased AP-1 transcription factor binding are associated with the long term plasticity changes in epilepsy
    • Morris T.A., Jafari N., and DeLorenzo R.J. Chronic DeltaFosB expression and increased AP-1 transcription factor binding are associated with the long term plasticity changes in epilepsy. Brain Res. Mol. Brain Res. 79 (2000) 138-149
    • (2000) Brain Res. Mol. Brain Res. , vol.79 , pp. 138-149
    • Morris, T.A.1    Jafari, N.2    DeLorenzo, R.J.3
  • 45
    • 0021279736 scopus 로고
    • Voltage-dependent calcium channels from brain incorporated into planar lipid bilayers
    • Nelson M.T., French R.J., and Krueger B.K. Voltage-dependent calcium channels from brain incorporated into planar lipid bilayers. Nature 308 (1984) 77-80
    • (1984) Nature , vol.308 , pp. 77-80
    • Nelson, M.T.1    French, R.J.2    Krueger, B.K.3
  • 46
    • 0033386966 scopus 로고    scopus 로고
    • In vitro status epilepticus causes sustained elevation of intracellular calcium levels in hippocampal neurons
    • Pal S., Sombati S., Limbrick Jr. D.D., and DeLorenzo R.J. In vitro status epilepticus causes sustained elevation of intracellular calcium levels in hippocampal neurons. Brain Res. 851 (1999) 20-31
    • (1999) Brain Res. , vol.851 , pp. 20-31
    • Pal, S.1    Sombati, S.2    Limbrick Jr., D.D.3    DeLorenzo, R.J.4
  • 47
    • 0033754595 scopus 로고    scopus 로고
    • Induction of spontaneous recurrent epileptiform discharges causes long-term changes in intracellular calcium homeostatic mechanisms
    • Pal S., Limbrick Jr. D.D., Rafiq A., and DeLorenzo R.J. Induction of spontaneous recurrent epileptiform discharges causes long-term changes in intracellular calcium homeostatic mechanisms. Cell Calcium 28 (2000) 181-193
    • (2000) Cell Calcium , vol.28 , pp. 181-193
    • Pal, S.1    Limbrick Jr., D.D.2    Rafiq, A.3    DeLorenzo, R.J.4
  • 48
    • 0034750682 scopus 로고    scopus 로고
    • Epileptogenesis induces long-term alterations in intracellular calcium release and sequestration mechanisms in the hippocampal neuronal culture model of epilepsy
    • Pal S., Sun D., Limbrick D., Rafiq A., and DeLorenzo R.J. Epileptogenesis induces long-term alterations in intracellular calcium release and sequestration mechanisms in the hippocampal neuronal culture model of epilepsy. Cell Calcium 30 (2001) 285-296
    • (2001) Cell Calcium , vol.30 , pp. 285-296
    • Pal, S.1    Sun, D.2    Limbrick, D.3    Rafiq, A.4    DeLorenzo, R.J.5
  • 49
    • 0034780784 scopus 로고    scopus 로고
    • Chronic inhibition of cortex microsomal Mg(2+)/Ca(2+) ATPase-mediated Ca(2+) uptake in the rat pilocarpine model following epileptogenesis
    • Parsons J.T., Churn S.B., and DeLorenzo R.J. Chronic inhibition of cortex microsomal Mg(2+)/Ca(2+) ATPase-mediated Ca(2+) uptake in the rat pilocarpine model following epileptogenesis. J. Neurochem. 79 (2001) 319-327
    • (2001) J. Neurochem. , vol.79 , pp. 319-327
    • Parsons, J.T.1    Churn, S.B.2    DeLorenzo, R.J.3
  • 50
    • 0002828857 scopus 로고
    • Calcium and epilepsy
    • Pedley T.A., and Meldrum B.S. (Eds), Churchill Livingstone, Edinburgh
    • Perlin J.B., and DeLorenzo R.J. Calcium and epilepsy. In: Pedley T.A., and Meldrum B.S. (Eds). "Recent Advances in Epilepsy, 5" (1992), Churchill Livingstone, Edinburgh 15-36
    • (1992) "Recent Advances in Epilepsy, 5" , pp. 15-36
    • Perlin, J.B.1    DeLorenzo, R.J.2
  • 51
    • 0034674485 scopus 로고    scopus 로고
    • Molecular mechanisms associated with long-term consolidation of the NMDA signals
    • Platenik J., Kuramoto N., and Yoneda Y. Molecular mechanisms associated with long-term consolidation of the NMDA signals. Life Sci. 67 (2000) 335-364
    • (2000) Life Sci. , vol.67 , pp. 335-364
    • Platenik, J.1    Kuramoto, N.2    Yoneda, Y.3
  • 52
    • 0035827071 scopus 로고    scopus 로고
    • Long-term alteration of calcium homeostatic mechanisms in the pilocarpine model of temporal lobe epilepsy
    • Raza M., Pal S., Rafiq A., and DeLorenzo R.J. Long-term alteration of calcium homeostatic mechanisms in the pilocarpine model of temporal lobe epilepsy. Brain Res. 903 (2001) 1-12
    • (2001) Brain Res. , vol.903 , pp. 1-12
    • Raza, M.1    Pal, S.2    Rafiq, A.3    DeLorenzo, R.J.4
  • 53
    • 10644229215 scopus 로고    scopus 로고
    • Evidence that injury-induced changes in hippocampal neuronal calcium dynamics during epileptogenesis cause acquired epilepsy
    • Raza M., Blair R.E., Sombati S., Carter D.S., Deshpande L.S., and DeLorenzo R.J. Evidence that injury-induced changes in hippocampal neuronal calcium dynamics during epileptogenesis cause acquired epilepsy. Proc. Natl. Acad. Sci. USA 101 (2004) 17522-17527
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 17522-17527
    • Raza, M.1    Blair, R.E.2    Sombati, S.3    Carter, D.S.4    Deshpande, L.S.5    DeLorenzo, R.J.6
  • 54
    • 0032567777 scopus 로고    scopus 로고
    • NMDA receptor activation during status epilepticus is required for the development of epilepsy
    • Rice A.C., and DeLorenzo R.J. NMDA receptor activation during status epilepticus is required for the development of epilepsy. Brain Res. 782 (1998) 240-247
    • (1998) Brain Res. , vol.782 , pp. 240-247
    • Rice, A.C.1    DeLorenzo, R.J.2
  • 55
    • 0025050694 scopus 로고
    • Antiepileptic drugs: Pharmacological mechanisms and clinical efficacy with consideration of promising developmental stage compounds
    • Rogawski M.A., and Porter R.J. Antiepileptic drugs: Pharmacological mechanisms and clinical efficacy with consideration of promising developmental stage compounds. Pharmacol. Rev. 42 (1990) 223-286
    • (1990) Pharmacol. Rev. , vol.42 , pp. 223-286
    • Rogawski, M.A.1    Porter, R.J.2
  • 56
    • 0028898916 scopus 로고
    • Recurrent spontaneous seizure activity in hippocampal neuronal networks in culture
    • Sombati S., and DeLorenzo R.J. Recurrent spontaneous seizure activity in hippocampal neuronal networks in culture. J. Neurophysiol. 73 (1995) 1706-1711
    • (1995) J. Neurophysiol. , vol.73 , pp. 1706-1711
    • Sombati, S.1    DeLorenzo, R.J.2
  • 57
    • 0026086592 scopus 로고
    • Neurotoxic activation of glutamate receptors induces an extended neuronal depolarization in cultured hippocampal neurons
    • Sombati S., Coulter D.A., and DeLorenzo R.J. Neurotoxic activation of glutamate receptors induces an extended neuronal depolarization in cultured hippocampal neurons. Brain Res. 566 (1991) 316-319
    • (1991) Brain Res. , vol.566 , pp. 316-319
    • Sombati, S.1    Coulter, D.A.2    DeLorenzo, R.J.3
  • 58
    • 0024315280 scopus 로고
    • NMDA antagonists differentiate epileptogenesis from seizure expression in an in vitro model
    • Stasheff S.F., Anderson W.W., Clark S., and Wilson W.A. NMDA antagonists differentiate epileptogenesis from seizure expression in an in vitro model. Science 245 (1989) 648-651
    • (1989) Science , vol.245 , pp. 648-651
    • Stasheff, S.F.1    Anderson, W.W.2    Clark, S.3    Wilson, W.A.4
  • 59
    • 0034798390 scopus 로고    scopus 로고
    • Glutamate injury-induced epileptogenesis in hippocampal neurons: An in vitro model of stroke-induced "epilepsy."
    • Sun D.A., Sombati S., and DeLorenzo R.J. Glutamate injury-induced epileptogenesis in hippocampal neurons: An in vitro model of stroke-induced "epilepsy.". Stroke 32 (2001) 2344-2350
    • (2001) Stroke , vol.32 , pp. 2344-2350
    • Sun, D.A.1    Sombati, S.2    DeLorenzo, R.J.3
  • 60
    • 0036852605 scopus 로고    scopus 로고
    • Calcium-dependent epileptogenesis in an in vitro model of stroke-induced "epilepsy."
    • Sun D.A., Sombati S., Blair R.E., and DeLorenzo R.J. Calcium-dependent epileptogenesis in an in vitro model of stroke-induced "epilepsy.". Epilepsia 43 (2002) 1296-1305
    • (2002) Epilepsia , vol.43 , pp. 1296-1305
    • Sun, D.A.1    Sombati, S.2    Blair, R.E.3    DeLorenzo, R.J.4
  • 61
    • 0942266254 scopus 로고    scopus 로고
    • Long-lasting alterations in neuronal calcium homeostasis in an in vitro model of stroke-induced epilepsy
    • Sun D.A., Sombati S., Blair R.E., and DeLorenzo R.J. Long-lasting alterations in neuronal calcium homeostasis in an in vitro model of stroke-induced epilepsy. Cell Calcium 35 (2004) 155-163
    • (2004) Cell Calcium , vol.35 , pp. 155-163
    • Sun, D.A.1    Sombati, S.2    Blair, R.E.3    DeLorenzo, R.J.4
  • 62
    • 0036140053 scopus 로고    scopus 로고
    • Mitochondrial calcium homeostasis: Mechanisms and molecules
    • Vandecasteele G., Szabadkai G., and Rizzuto R. Mitochondrial calcium homeostasis: Mechanisms and molecules. IUBMB Life 52 (2001) 213-219
    • (2001) IUBMB Life , vol.52 , pp. 213-219
    • Vandecasteele, G.1    Szabadkai, G.2    Rizzuto, R.3
  • 63
    • 0027992583 scopus 로고
    • Phenylglycine derivatives as antagonists of metabotropic glutamate receptors
    • Watkins J., and Collingridge G. Phenylglycine derivatives as antagonists of metabotropic glutamate receptors. Trends Pharmacol. Sci. 15 (1994) 333-342
    • (1994) Trends Pharmacol. Sci. , vol.15 , pp. 333-342
    • Watkins, J.1    Collingridge, G.2
  • 64


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.