Controversies in surgical oncology: Routine anthracycline-based adjuvant chemotherapy for stage III extremity soft tissue sarcoma

Annals of Surgical Oncology

Volumn 14, Issue 4, 2007, Pages 1254-1256

  Bramwell, Vivien H C ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE DERIVATIVE; DACARBAZINE; DOXORUBICIN; EPIRUBICIN; IFOSFAMIDE;

CANCER ADJUVANT THERAPY; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER RELAPSE; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CLINICAL TRIAL; DISEASE FREE SURVIVAL; DRUG EFFICACY; HUMAN; LIMB SALVAGE; MICROMETASTASIS; REVIEW; RISK BENEFIT ANALYSIS; SOFT TISSUE SARCOMA; TREATMENT RESPONSE; UNSPECIFIED SIDE EFFECT;

ANTHRACYCLINES; ANTINEOPLASTIC AGENTS; CHEMOTHERAPY, ADJUVANT; CLINICAL TRIALS; HUMANS; MEDICAL ONCOLOGY; SARCOMA; SOFT TISSUE NEOPLASMS;

EID: 34047228420     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-006-9168-8     Document Type: Review

References (29)

1. Greene FL, Page DL, Fleming ID, et al. (2002) AJCC cancer staging handbook, 6th edn. Berlin, Heidelberg, New York: Springer.
2. Early Breast Cancer Trialists Collaborative Group (EBCTCG) Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomized trials. Lancet 2005; 365:1687-717.
3. Bramwell VHC. The role of chemotherapy in the management of non-metastatic operable extremity osteosarcoma. Sem Oncol 1997; 20:561-71.
4. Lewis I, Burchill S, Souhami R. (2002) Ewing's sarcoma and the Ewing family of tumours. Souhami RL, Tannock I, Hohenberger P, Horiot JC. In: Oxford textbook of oncology, 2nd edn. Oxford: Oxford University Press, pp 2539-51.
5. Sarcoma Meta-analysis Collaboration Adjuvant chemotherapy for localized resectable soft-tissue sarcoma of adults: meta-analysis of individual data. Lancet 1997; 350:1647-54.
6. Frustaci S, Gherlinzoni F, De Paoli A, et al. Adjuvant chemotherapy for adult soft tissue sarcomas of the extremities and girdles: results of the Italian randomized cooperative trial. J Clin Oncol 2001; 19:1238-47.
7. Bramwell VHC. Adjuvant chemotherapy for adult soft tissue sarcoma: is there a standard of care?. J Clin Oncol 2001; 19:1235-7 (Editorial).
8. Frustaci S, De Paoli A, Bidoli E, et al. Ifosfamide in the adjuvant therapy of soft tissue sarcomas. Oncology 2003; 65:80-4.
9. Petrioli R, Coratti A, Correale P, et al. Adjuvant epirubicin with or without ifosfamide for adult soft-tissue sarcoma. Am J Clin Oncol 2002; 25:468-73.
10. Bordowicz T, Schwaneis E, Widder J, et al. Intensified adjuvant IFADIC chemotherapy for adult soft tissue sarcoma: a prospective randomized feasibility trial. Sarcoma 2000; 4:151-60.
11. Pisters PWT, Patel SR, Varma DGK, et al. Preoperative chemotherapy for stage IIIB extremity soft tissue sarcoma: long-term results from a single institution. J Clin Oncol 1997; 15:3481-7.
12. Wodajo FM, Wittig J, Kumar D, et al. Successful treatment of high grade soft tissue sarcoma with induction chemotherapy: clinicopathological analysis of thick capsule formation allowing less extensive "marginal" surgical resection. Proc Am Soc Clin Oncol 2001; 20:290b (A2912).
13. Fernandez GL, Benedetto P. Neoadjuvant chemotherapy for adult, nonmetastatic, intermediate (G2) or high grade (G3) appendicular soft tissue sarcoma. Proc of Am Soc Clin Oncol 2002; 21:281b (A2943).
14. Lindner LH, Schlemmer M, Hohenberger H, et al. First interim report on the randomized EORTC 62962/ESHO-RHY 95 Intergroup study (phase III) combined with regional hyperthermia (RHT) versus chemotherapy alone in the treatment of high-risk soft tissue sarcomas (HR-STS) in adults. Proc Am Soc Clin Oncol 2004; 23:817 (A9015).
15. Lindner LH, Schlemmer M, Hohenberger P, et al. Risk assessment of early progression among 213 pts with high-risk soft tissue sarcomas (HR-STS) treated with neoadjuvant chemotherapy ± regional hyperthermia: EORTC 62961/ESHORHT 95 intergroup phase III study. Proc Am Soc Clin Oncol 2005; 23:821 (A3276).
16. Abuin GG, Lassalle M, Bonvalot S, et al. Intensive induction chemotherapy (API-AI regimen) followed by conservative surgery in adult patients with locally advanced soft tissue sarcoma (STS): survival is predicted by the histological response. Proc Am Soc Clin Oncol 2004; 23:823 (A9036).
17. Grobmyer SR, Maki RG, Demetri GD, et al. Neo-adjuvant chemotherapy for primary high-grade extremity soft tissue sarcoma. Ann Oncol 2004; 15:1667-72.
18. Eilber FC, Rosen G, Eckardt J, et al. Treatment-induced pathologic necrosis: a predictor of local recurrence and survival in patients receiving neoadjuvant therapy for high-grade extremity soft tissue sarcomas. J Clin Oncol 2001; 19:3203-9.
19. DeLaney TF, Spiro IJ, Suit HD, et al. Neoadjuvant chemotherapy and radiotherapy for large extremity soft-tissue sarcomas. Int J Rad Oncol Biol Phys 2003; 56:1117-27.
20. Kraybill WG, Harris JH, Spiro I, et al. Radiation Therapy Oncology Group (RTOG) 9514: a phase II study of neoadjuvant chemotherapy (CT) and radiation therapy (RT) in the management of high risk (HR), high grade, soft tissue sarcomas (STS) of the extremities and body wall. Proc Am Soc Clin Oncol 2003; 22:815-(A3276).
21. Pisters PWT, Patel SR, Prieto VG, et al. Phase I trial of preoperative Doxorubicin-based concurrent chemoradiation and surgical resection for localized extremity and body wall soft tissue sarcomas. J Clin Oncol 2004; 22:3375-80.
22. Gortzak E, Azzarelli A, Buesa J, et al. A randomized phase II study on neo-adjuvant chemotherapy for ,high-risk' adult soft-tissue sarcoma. Eur J Cancer 2001; 37:1096-103.
23. Bear HD, Anderson S, Smith RE, et al. A randomized trial comparing preoperative (preop) doxorubicin/cyclophosphamide (AC) to preop AC followed by preop docetaxel (T) and to preop AC followed by postoperative (postop) T in patients (pts) with operable carcinoma of the breast: results of NSABP B-27. Breast Cancer Res Treat 2004; 88:S16-(A26).
24. Goorin AM, Schwartzentruber DJ, Devidas M, et al. Presurgical chemotherapy compared with immediate surgery and adjuvant chemotherapy for nonmetastatic osteosarcoma: Pediatric Oncology Group Study POG-8651. J Clin Oncol 2003; 21:1574-80.
25. Cormier JN, Huang X, Xing Y, et al. Cohort analysis of patients with localized, high-risk, extremity soft tissue sarcoma treated at two cancer centers: chemotherapy-associated outcomes. J Clin Oncol 2004; 22:4567-74.
26. Nielsen TO, West RB, Linn SC, et al. Molecular characterisation of soft tissue tumours: a gene expression study. Lancet 2002; 359:1263-4.
27. Segal NH, Pavlidis P, Antonescu CR, et al. Classification and subtype prediction of adult soft tissue sarcoma by functional genomics. Am J Pathol 2003; 163:691-700.
28. Borden EC, Baker LH, Bell RS, et al. Soft tissue sarcomas of adults: state of the translational science. Clin Cancer Res 2003; 9:1941-56.
29. Baird K, Davis S, Antonescu CR, et al. Gene expression profiling of human sarcomas: insights into sarcoma biology. Cancer Res 2005; 65:9226-35.