Electroporation enhances radiation and doxorubicin-induced toxicity in solid tumor in vivo

Journal of Environmental Pathology, Toxicology and Oncology

Volumn 25, Issue 4, 2006, Pages 625-632

  Shil, Pratip ^a   Kumar, Amit ^b   Vidyasagar, Pandit B ^a   Mishra, Kaushala P ^b  

^a UNIVERSITY OF PUNE   (India)

^b BHABHA ATOMIC RESEARCH CENTRE   (India)

Author keywords

Doxorubicin (DOX); Electroporation (EP); Mice; Radiation; Tumor growth delay (TGD)

Indexed keywords

DOXORUBICIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER INHIBITION; CANCER RADIOTHERAPY; CONTROLLED STUDY; ELECTROPORATION; FIBROSARCOMA; GAMMA RADIATION; HINDLIMB; IONIZING RADIATION; MOUSE; MULTIMODALITY CANCER THERAPY; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE; SOLID TUMOR; TREATMENT OUTCOME;

MURINAE; MUS;

EID: 34047224112     PISSN: 07318898     EISSN: None     Source Type: Journal    
DOI: 10.1615/JEnvironPatholToxicolOncol.v25.i4.20     Document Type: Article

References (26)

1. Levi R, Miller RA. Antibodies I cancer therapy. In: De Vita VT Jr, Hellman, Rosenberg SA, editors. Biologic therapy of cancer. Philadelphia: Lippincott; 1991.
2. Steerenberg PA, Stom G, De Groot G. Liposomes as drug career system for Cis-diamminedichloroplatinum(II). II antitumor activity in vivo , induction of drug resistance, nephotoxicity and Pt Distribution. Cancer Chemoth Pharmacol. 1988;21:299-307
3. Lubbe AS, Bergemann C , Reiss H , Huhnt W, Fricke T, Brick J, Huhn D. Clinical experience with magnetic drug targeting: phase I trials with 4′-epidoxorubicin in 4 patients with advanced solid tumors. Can Res. 1996;56:4686-93.
4. Jekunen AP, Shalinsky DR, Hom DK. Modulation of Cisplatin cytotoxicity by permeabilization of plasma membrane by digitonin in vitro. Biochem Pharmacol. 1993;45:2079-85.
5. Marverti G, Andrew PA, Piccini G, Ghiaroni S, Barbeiri D, Moruzzi M. Modulation of Cisdiamminedichloroplatinum(II) accumulation and toxicity by spermine in sensitive and resistant human ovarian carcinoma cells. Eur J Cancer. 1997;33:669-75.
6. Neumann E, Sowers A., Jordan C. Electroporation and electrofusion in cell biology. New York: Plenum Press, 1989.
7. Kinosita K, Tsong TY. Formation and resealing of pores of controlled sizes in human erythrocyte membrane. Nature. 1977;268:438-41.
8. Nanda G.S., K.P.Mishra, Studies on electroporation of thermally and chemically treated erythrocytes. Bioelectrochem Bioeng. 1994;34:189-93.
9. Mir LM. Therapeutic perspectives of in-vivo cell electropermeabilization. Bioelectrochem. 2000;53:1-10.
10. Shil P, Kumar A, Vidyasagar PB, Mishra KP. Cell electroporation: Biophysical basis and applications to cancer therapy. Phys Edu. 2004;21(1):17-28.
11. Gabriel B, Teissie J. Time course of mammalian call electropermeabilizatiom observed by millisecond imaging of membrane property changes during pulse. Biophys J. 1999;76:2158-65.
12. Weaver JC, Chizmadzhev YuA. Theory of electroporation: A review. Bioelectrochem Bioenerg. 1996;41:135-60.
13. Abidor IG, Arakelyan VB, Chernomomordik LV, Chizmadzhev YA, Pastushenko VP, Tarasevich MR. Electrical breakdown of bilayer lipid membranes: I main experimental facts and their qualitative discussion. Bioelectrochem Bioenerg. 1997;6:37-52.
14. Mir LM, Orlowski S. Mechanisms of electrochemotherapy. Adv Drug Deliv Rev 1999;35:107-18.
15. Heller R, Gilbert R, Jaroszeski M. Clinical Applications of electrochemotherapy. Adv Drug Deliv Rev. 1999;35:119-29.
16. Sersa G, Cemazar M, Miklavcic D. Antitumor effectiveness of Electrochemotherapy with Cis-diamminedichloroplatinum (II). Cancer Res. 1995;55:3450-5.
17. Cemazar M, Miklavcic D, Scancar J, Dolzan V, Golouh R, Sersa G. Increased platinum accumulation in SA-1 tumor cells after in vivo chemotherapy with Cisplatin. Br J Cancer. 1999;79:1386-91.
18. Shil P, Sanghvi S, Vidyasagar PB, Mishra KP. Enhancement of radiation cytotoxicity in murine cancer cells by electroporation: in vitro and in vivo studies. J Environ Pathol Toxicol Oncol. 2005;24(4):291-8.
19. Gopal R, Narkar AA, Mishra KP, Samuel AM, Nair N . Electroporation: a novel approach to enhance the radio-iodine uptake in a human thyroid cancer cell line. Appl Radiat Isotop. 2003;59:305-10.
20. Sersa G, Cemazar M, Menart V, Gaberc-Porekar V, Miklavcic D. Anti-tumor effectiveness of Electrochemotherapy with bleomycin is increased by TNF-α on SA-1 tumor in mice. Cancer Lett. 1997;116:85-92.
21. Mir LM, Orlowski S, Belehradek J, Paoletti C. Electrochemotherapy potentiation of antitumor effects of Bleomycin by local electric pulses. Eur J Cancer. 1991;27:68-72.
22. Sersa G, Cemazar M, Miklavcic D, Mir LM. Electrochemotherapy: variable antitumor effect on different tumor models. Bioelectrochem Bioenerg. 1994;35:23-7.
23. Heller R, Jaroszeski M, Leo-Messina J, Perrott R, Van Voorhis N, Reintgen D, Gilbert R. Treatment of B16 mouse melanoma with the combination of electropermeabilization and chemotherapy. Bioelectrochem Bioenerg. 1995;36:83-7.
24. Hui YW, Kang JK. Inhibition of Buthionine Sulfoximine-enhanced Doxorubicin toxicity in metallothionein over expressing transgenic mouse heart. J Pharmacol Exp Therapeut. 1998;287(2):515-20.
25. Kenji M., Tomohiro T., Yoshiaki Y., Honda. N, Fukatsu. H, Yoshikawa K. In-vitro and in-vivo studies of the efficacy of electrochemotherapy for renal cell carcinoma, Int J Clin Oncol. 2000;5:303-7.
26. Satkauskas S, Batiuskaite D, Salomskaite-Davalgiene S, Venslauskas. Effectiveness of tumor Electrochemotherapy as a function of electric pulse strength and duration. Bioelectrochem. 2005;65:105-10.