Enhancement of radiation cytotoxicity in murine cancer cells by electroporation: In vitro and in vivo studies

Journal of Environmental Pathology, Toxicology and Oncology

Volumn 24, Issue 4, 2005, Pages 291-298

  Shil, Pratip ^a,b   Sanghvi, Surendra H ^b   Vidyasagar, Pandit B ^a   Mishra, Kaushala P ^b  

^a UNIVERSITY OF PUNE   (India)

^b BHABHA ATOMIC RESEARCH CENTRE   (India)

Author keywords

Ehrlich ascites carcinoma; Electroporation; Fibrosarcoma; Fluorescence; Membrane fluidity; Oxidative stress; Radiation; Reactive oxygen species; Tumor growth; rays

Indexed keywords

1,6 DIPHENYL 1,3,5 HEXATRIENE; DICHLORODIHYDROFLUORESCEIN DIACETATE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER RADIOTHERAPY; CANCER THERAPY; CELL MEMBRANE; CELL MEMBRANE FLUIDITY; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; EHRLICH ASCITES TUMOR; ELECTRIC CURRENT; ELECTROPORATION; FIBROSARCOMA; FLUORESCENCE; GAMMA RADIATION; IN VITRO STUDY; IN VIVO STUDY; INSTRUMENT; IONIZING RADIATION; LOW ENERGY RADIATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; TUMOR GROWTH; ANIMAL; CANCER TRANSPLANTATION; CELL DEATH; CELL SURVIVAL; COMPARATIVE STUDY; MEMBRANE FLUIDITY; METABOLISM; MULTIMODALITY CANCER THERAPY; PATHOLOGY; RADIATION EXPOSURE; RADIATION RESPONSE; TUMOR CELL LINE;

ANIMALIA; MURINAE;

ANIMALS; CARCINOMA, EHRLICH TUMOR; CELL DEATH; CELL LINE, TUMOR; CELL SURVIVAL; COMBINED MODALITY THERAPY; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTROPORATION; FIBROSARCOMA; GAMMA RAYS; MEMBRANE FLUIDITY; MICE; NEOPLASM TRANSPLANTATION; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 33644845455     PISSN: 07318898     EISSN: None     Source Type: Journal    
DOI: 10.1615/JEnvironPatholToxicolOncol.v24.i4.60     Document Type: Article

References (16)

1. Kinosita K, Tsong TY. Formation and resealing of pores of controlled sizes in human erythrocyte membrane. Nature. 1977;268:438-41.
2. Isambert H. Understanding the electroporation of cells and artificial bilayer membranes. Phys Rev Lett. 1998;80:3404-7.
3. Nanda GS, Mishra KP. Studies on electroporation of thermally and chemically human erythrocytes. Bioelectrochem Bioeng. 1994;34:189-93.
4. Mir LM. Therapeutic perspectives of in-vivo cell electropermeabilization. Bioelectrochemistry 2000;53:1-10.
5. Ojeda F, Diehl HA, Floch H. Radiation induced membrane changes and programmed cell death: possible interrelationships. Scann Micros. 1994;3: 645-51.
6. Pandey BN, Mishra KP. Oxidative membrane damage and its involvement in radiation induced apoptotic cell death. Iran J Radiat Res. 2003;1:17-22.
7. Hibino M, Itoh H, Kinosita K Jr. Time courses of electroporation as revealed by the submicrosec imaging of transmembrane potential. Biophys J. 1993;64:1789-800.
8. Weaver JC, Chizmadzhev YA. Theory of electroporation: a review. Bioelectrochem Bioenerget. 1996;41:135-60.
9. Mir LM, Orlowski S. Mechanisms of electrochemotherapy. Adv Drug Del Rev. 1999;35: 107-18.
10. Sersa G, Kranjc S, Cemazar M. Improvement of combined modality therapy with cisplatin and radiation using electroporation of tumors. Int J Radiation Oncol Biol Phys. 2000;46:1037-41.
11. Gopal R, Narkar AA, Mishra KP, Samuel AM, Nair N. Electroporation: a novel approach to enhance the radioiodine uptake in a human thyroid cancer cell line. Appl Radiat Isot. 2003;59:305-10.
12. Pandey BN, Mishra KP. In vitro studies on radiation induced membrane oxidative damage in apoptotic death of mouse thymocytes. Intl J Low Radiat. 2003;1:113-9.
13. Mitsui K, Taki T, Yamada Y, Honda N, Fukatsu H, Yoshikawa K. In-vitro and in-vivo studies of the efficacy of electrochemotherapy for renal cell carcinoma. Int J Clinical Oncol. 2000;5:303-7.
14. Mishra KP. Cell membrane oxidative damage induced by gamma radiation and apoptotic sensitivity. J Environ Pathol Toxicol Oncol. 2004;23:61-6.
15. Pandey BN, Mishra KP. Modification of thymocytes membrane radiooxidative damage and apoptosis by eugenol. J Environ Pathol Toxicol Oncol. 2004;23:117-22.
16. Weaver JC. Electroporation of cells and tissues. IEEE Trans Plasma Sci. 2000;28:24-32.