The influence of shark liver oils on normal and transformed mammalian cells in culture

In Vivo

Volumn 21, Issue 2, 2007, Pages 333-338

  Davidson, Bruce C ^a   Rottanburg, D ^a   Prinz, W ^a   Cliff, G ^b  

^a UNIVERSITY OF THE WITWATERSRAND MEDICAL SCHOOL   (South Africa)

^b Natal Sharks Board   (South Africa)

Author keywords

Cancer cells; Fatty acids; Shark liver oil

Indexed keywords

EDIBLE OIL; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; SHARK LIVER OIL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER INHIBITION; CELL CULTURE; CELL PROLIFERATION; CELL TRANSFORMATION; HUMAN; HUMAN CELL; MAMMAL CELL; MOUSE; NONHUMAN; SHARK; SPECIES DIFFERENCE;

EID: 34047208935     PISSN: 0258851X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Giangregorio A: The influence of fatty acids in vitro on mammalian cells from species differing in their fatty acyl desaturase capabilities. Ph.D. Thesis, University of the Witwatersrand, Johannesburg, South Africa, 1992.
2. Cantrill RC, Davidson BC, Katzeff I and Booyens J: The effects of essential fatty acid supplementation on the fatty acid composition of cancer cells in culture. Prog Lipid Res 25: 547-550, 1986.
3. Girao LA, Ruck AC, Cantrill RC and Davidson BC: The effect of C18 fatty acids on cancer cells in culture. Anticancer Res 6: 241-244, 1986.
4. Davidson BC, Girao LAF, Giangregorio A and Murphy J: Polyunsaturated fatty acids modulate fibroblast growth in culture. Anticancer Res 11: 267-272, 1991.
5. Davidson BC, Giangregorio A and Girao LAF: The influence of C18 fatty acids on the growth of fibroblasts of different degrees of transformation in culture. Anticancer Res 13: 795-800, 1993.
6. Davidson BC, Giangregorio A and Girao LAF: The influence of fatty acids on normal and transformed human liver cells in culture. Anticancer Res 18: 3533-3538, 1998.
7. van der Merwe CF, Booyens J and Katzeff IE: Oral gamma-linolenic acid in 21 patients with untreatable malignancy - an ongoing pilot open clinical trial. Br J Clin Pract 41: 907-915, 1987.
8. Davidson BC, Girao LAF and Giangregorio A: Differential influence of pre- and post-delta-6-desaturation n6 polyunsaturated fatty acids on fibroblasts in culture, compared to n9 monounsaturated and n3 polyunsaturated fatty acids. In Vivo 19: 221-224, 2005.
9. Heidmann-Soccol MC and Oetterer M: Seafood as a functional food. Braz Arch Biol 7-46: 443-454, 2003.
10. Jayasinghe C, Gotoh N, Tokairin S, Ehara H and Wada S: Inter species changes of lipid compositions in liver of shallow-water sharks from the Indian Ocean. Fisheries Science 69: 644-653, 2003.
11. Larsson SC, Kumlin M, Ingelman-Sundberg M and Wolk A: Dietary long chain n3 fatty acids for the prevention of cancer: a review of potential mechanisms. Am J Clin Nutr 79: 935-945, 2004.
12. Sasaki T, Kobayashi Y, Shimizu J, Wada M, In'nami S, Kanke Y and Takita T: Effects of dietary n3-to-n6 polyunsaturated fatty acid ratio on mammary carcinogenesis in rats. Cancer 30: 137-143, 1998.
13. Hardman WE: (n3) Fatty acids and cancer therapy. J Nutr 134: 3427S-3430S, 2004.
14. Man-Fan Wan J, Kanders BS, Kowalchuk M, Knapp H, Szeluga DJ, Bagley J and Blackburn GL: N3 fatty acids and cancer metastasis in humans. World Rev Nutr Diet 66: 477-487, 1991.
15. Galli C and Butrum R: Dietary n3 fatty acids and cancer: an overview. World Rev Nutr Diet 66: 446-461, 1991.
16. Solomon N, Passwater R and Joelsson I: Shark liver oil and cancer. In: Shark Liver Oil-natures Amazing Healer. New York, Kensington publishing company, pp. 49-54, 1997.
17. Wetherbee BM and Nichols PD: Lipid composition of the liver oil of deep-sea sharks from the Chatham Rise, New Zealand. Comp Biol Physiol B 125: 511-521, 2000.
18. Skopinska-Rosewska E, Krotkiewski IM, Sommer E, Rogala E, Filewska M and Bialas-Chromeic B: Inhibitory effect of shark liver oil on cutaneous angiogenesis induced in Balb/c mice by syngeneic sarcoma L-1, human urinary bladder and human kidney tumour cells. Oncol Rep 6: 1341-1344, 1999.
19. Navarro-Garcia G, Pacheco-Aguilar R, Vellejo-Cordova B, Ramirez-Suarez JC and Bolanos A: Lipid composition of the liver oil of shark species from the Caribbean and Gulf of California waters. J Food Compos Anal 13: 791-798, 2000.
20. Lane IW: Sharks don't get cancer. Avery Publishing Group, New York, pp. 1-100, 1992.
21. Lane IW: Sharks still don't get cancer. Avery Publishing Group, New York, pp. 1-43, 1996.
22. Ostrander GK, Cheng KC, Wolf JC and Wolfe MJ: Shark cartilage, cancer and the growing threat of pseudoscience. Cancer Res 64: 8485-8491, 2004.
23. Bligh EG and Dyer WJ: A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37: 911-917, 1959.
24. Kay MMB and Makinodan T: CRC Handbook of Immunology in Aging. CRC Press, Boca Raton, USA, pp. 30-40, 1981.
25. Girao LAF: To determine the in vitro effects of C18 fatty acids on normal, malignant and benign cell lines. Ph.D. Thesis, University of the Witwatersrand, Johannesburg, South Africa, 1988.
26. Paul J: Cell viability by Trypan Blue Exclusion. In: Cell and Tissue Culture. Churchill Livingstone Press, London, pp. 367-368, 1975.
27. Pugliese PT, Jordan K, Cederberg H and Brohult J: Some biological actions of alkylglycerols from shark liver oil. J Altern Complement Med 4: 87-99, 1998.