Preparation and evaluation of liposomes encapsulating synthetic MMP inhibitor (Ro 28-2653) - Cyclodextrin complexes

Journal of Inclusion Phenomena and Macrocyclic Chemistry

Volumn 57, Issue 1-4, 2007, Pages 101-103

  Piette, Marie ^a   Castagne, Delphine ^a   Delattre, Luc ^a   Piel, Géraldine ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Cyclodextrin; Liposome; Matrix metalloproteinase inhibitor; Release kinetics; Ro 28 2653

Indexed keywords

EID: 34047185747     PISSN: 09230750     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10847-006-9214-y     Document Type: Conference Paper

References (4)

1. Grams, F., et al: Pyrimidine-2,4,6-Triones: a new effective and selective class of matrix metalloproteinase inhibitors. Biol. Chem. 382, 1277-1285 (2001)
2. Lein, M., et al: The new synthetic matrix metalloproteinase inhibitor (Roche 28-2653) reduces tumor growth and prolongs survival in a prostate cancer standard rat model. Oncogene 21, 2089-2096 (2002)
3. Maquoi, E., et al: Anti-invasive, antitumoral, and antiangiogenic efficacy of a pyrimidine-2,4,6-trione derivative, an orally active and selective matrix metalloproteinases inhibitor. Clin. Cancer Res. 10, 4038-4047 (2004)
4. 1H-NMR spectroscopy and molecular modeling studies, preparation and stability study of nebulizable solutions. J. Pharm. Pharm. Sci. 8, 164-175 (2005)