Mechanisms of epithelial dysfunction in giardiasis

Gut

Volumn 56, Issue 3, 2007, Pages 316-317

  Buret, Andre G ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; CELL FUNCTION; ELECTROLYTE TRANSPORT; GIARDIA LAMBLIA; GIARDIASIS; HUMAN; INTESTINE CELL; INTESTINE EPITHELIUM; NOTE; PARASITE VIRULENCE; PATHOPHYSIOLOGY; PREVALENCE; PRIORITY JOURNAL; ANIMAL; GIARDIA; INTESTINE INFECTION; INTESTINE MUCOSA; MALABSORPTION; PARASITOLOGY; PATHOGENICITY; PATHOLOGY; PERMEABILITY; VIRULENCE;

ANIMALS; APOPTOSIS; ENTEROCYTES; GIARDIA; GIARDIASIS; HUMANS; INTESTINAL DISEASES, PARASITIC; INTESTINAL MUCOSA; MALABSORPTION SYNDROMES; PERMEABILITY; VIRULENCE;

EID: 34047125205     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.2006.107771     Document Type: Note

References (39)

1. Mueller N, von Allmen N. Recent insights into the mucosal reactions associated with Giardia lamblia infections. Int J Parasitol 2005;35:1339-47.
2. Faubert G. Immune responses to Giardia duodenalis. Clin Microbiol Rev 2000;13:35-54.
3. Buret AG, Scott KG-E, Chin AC. Giardiasis: pathophysiology and pathogenesis Giardia, the cosmopolitan parasite. CAB International, In: Olson B, Olson ME, Wallis PM, eds, Wallingford, UK:2002;109-27.
4. Gascon J. Epidemiology, etiology, and pathophysiology of traveler's diarrhea. Digestion 2006;73(Suppl):102-8.
5. Buret A, O'Loughlin EV, Curtis G, et al. Effect of acute Yersinia enterocolitica infection on small intestinal ultrastructure. Gastroenterology 1990;98:1401-7.
6. Buret A, Olson ME, Gall DG, et al. 1998. Effects of orally administered epidermal growth factor on enteropathogenic Escherichia coli infection in rabbits. Infect Immun 1998;66:4917-23.
7. Curtis GH, Patrick MK, Catto-Smith AG, et al. Intestinal anaphylaxis in the rat. Gastroenterology 1990;98:1558-66.
8. Rubin W, Ross LL, Sleisenger MH, et al. An electron microscopic study of adult celiac disease. Lab Invest 1996;15:1720-47.
9. Gunasekaran TS, Hassal E. Giardiasis mimicking inflammatory bowel disease. J Pediatr 1992;120:424-6.
10. Troeger H, Epple H-J, Schneider T, et al. Effect of chronic Giardia lamblia infection on epithelial transport and barrier function in human duodenum. Gut 2007;56:328-35.
11. Buret AG, Hardin JA, Olson ME, et al. Pathophysiology of small intestinal malabsorption in gerbils infected with G. lamblia. Gastroenterology 1992;103:506-13.
12. Cevallos A, Carnaby S, James M, et al. Small intestinal injury in a neonatal rat model of giardiasis is strain-dependent. Gastroenterology 1995;109:766-73.
13. Belosevic M, Faubert GM, Maclean JD. Disaccharidase activity in the small intestine of gerbils (Meriones unguiculatus) during primary and challenge infections with Giardia lamblia. Gut 1989;30:1213-1219.
14. Resta-Lenert S, Langford TD, Gillin FD, et al. Altered chlorid secretory responses in HT29/Cl. 19A cells infected with Giardia lamblia. Gastroenterology 2000;118:A684.
15. Gorowara S, Ganguly NK, Mahajan RC, et al. Study on the mechanism of Giardia lamblia-induced diarrhea in mice. Biochem Biophys Acta 1992;1138:122-6.
16. Scott KGE, Yu LCH, Buret AG. Role of CD8+ and CD4+ T lymphocytes in jejunal mucosal injury during murine giardiasis. Infect Immun 2004;72:3536-42.
17. Eckmann L. Mucosal defenses against Giardia. Parasite Immunol 2003;25:259-70.
18. Scott KGE, Logan MR, Klammer GM, et al. Jejunal brush border microvillous alterations in G. muris-infected mice: role of T lymphocytes and interleukin-6. Infect Immun 2000;68:3412-18.
19. Dagci H, Ustun S, Taner MS, et al. Protozoan infections and intestinal permeability. Acta Trop 2002;81:1-5.
20. Scott KG, Meddings JB, Kirk DR, et al. Intestinal infection with Giardia spp. reduces epithelial barrier function in a myosin light chain kinase-dependent fashion. Gastroenterology 2002;123:1179-90.
21. Hardin JA, Buret AG, Olson ME, et al. Mast cell hyperplasia and increased macromolecular uptake in an animal model of giardiasis. J Parasitol 1997;83:908-12.
22. Laukoetter MG, Bruewer M, Nusrat A. Regulation of the intestinal epithelial barrier by the apical junctional complex. Curr Opin Gastroenterol 2006;22:85-9.
23. Shen L, Black ED, Witkowski ED, et al. Myosin light chain phosphorylation regulates barrier function by remodelling tight junction structure. J Cell Sci 2006;119:2095-21.
24. Chin ACK, Teoh DA, Scott KGE, et al. Strain-dependent induction of enterocyte apoptosis by G. lamblia disrupts epithelial barrier function in a caspase-3-depenaent manner. Infect Immun 2002;70:3673-80.
25. Roxstroem-Lindquist K, Ringqvist E, Palm D, et al. Giardia lamblia-induced changes in gene expression in differentiated CaCo-2 human intestinal epithelial cells. Infect Immun 2005;73:8204-8.
26. Eckmann L, Laurent F, Langford TD, et al. Nitric oxide production by human intestinal epithelial cells and competition for arginine as potential determinants of host defense against the lumen-dwelling pathogen Giardia lamblia. J Immunol 2000;164:1478-87.
27. Potoka DA, Upperman JS, Zhang XR, et al. Peroxynitrite inhibits enterocyte proliferation and modulates Src kinase activity in vitro. Am J Physiol (Gastrointest Liver Physiol) 2003;285:G861-9.
28. Teoh DA, Kamieniecki D, Pang G, et al. Giardia lamblia rearranges F-actin and alpha-actinin in human colonic and duodenal monolayers and reduces transepithelial electrical resistance. J Parasitol 2000;86:800-6.
29. D'Anchino M, Orlando D, DeFeudis L. Giardia lamblia infections become clinically evident by eliciting symptoms of irritable bowel syndrome. J Infect 2002;45:169-72.
30. Kaur H, Ghosh S, Samra H, et al. Identification and characterization of an excretory-secretory product from Giardia lamblia. Parasitology 2001;123:347-56.
31. Jimenez JC, Fontaine J, Grzych JM, et al. Systemic and mucosal responses to oral administration of excretory-secretory antigens from Giardia intestinalis. Clin Diagn Lab Immunol 2004;11:152-60.
32. Chen N, Upcroft JA, Upcroft P. A Giardia duodenalis gene encoding multiple repeats of a toxin homologue. Parasitology 1995;111:423- 31.
33. Sousa MC, Goncalves CA, Bairos VA, et al. Adherence of Giardia lamblia trophozoites to Int-407 human intestinal cells. Clin Diagn Lab Immunol 2001;8:258-65.
34. Eckmann L, Gillin FD. Microbes and microbial toxins: paradigms for microbial-mucosal interactions. Pathophysiological aspects of enteric infections with the lumen-dwelling protozoan pathogen Giardia lamblia. Am J Physiol (Gastrointest Liver Physiol) 2001;280:G1-6.
35. Shant J, Ghosh S, Bhattacharyya S, et al. The alteration in signal transduction parameters induced by the excretory-secretory product for Giardia lamblia. Parasitology 2004;129:421-30.
36. Parenti DM. Characterization of thiol proteinase in Giardia lamblia. J Infect Dis 1989;160:1076-80.
37. Hare D F, Jarroll EL, Lindmark DG. Giardia lamblia: characterization of proteinase activity in trophozoites. Exp Parasitol 1989;68:168-75.
38. Chin AC, Vergnolle N, MacNaughton WK, et al. Proteinase-activated receptor 1 activation induces epithelial apoptosis and increases intestinal permeability. Proc Natl Acad Sci USA 2003;100:11104-9.
39. Adam RD. The Giardia lamblia genome. Int J Parasitol 2000;30:475-484.