Measuring airway inflammation in clinical practise - Application and interpretation;Messung der atemwegsentzündung in der pneumologischen praxis - Anwendung und interpretation

Pneumologie

Volumn 61, Issue 3, 2007, Pages 194-201

  Holz, Olaf ^a,b   Buhl, R ^a   Hausen, T ^a   Von Berg, A ^a   Weber, M ^a   Worth, H ^a   Magnussen, H ^a  

^a Institutsangaben Sind am Ende des Beitrags Gelistet ^*  (Germany)

^b KRANKENHAUS GROSSHANSDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; CORTICOSTEROID; NITRIC OXIDE;

ASTHMA; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL PRACTICE; CORRELATION ANALYSIS; EOSINOPHIL; GENERAL PRACTITIONER; HUMAN; INFLAMMATION; PRIORITY JOURNAL; REVIEW; SPUTUM ANALYSIS;

ADULT; AIRWAY OBSTRUCTION; ASTHMA; CHILD; HUMANS; INFLAMMATION; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

EID: 34047117936     PISSN: 09348387     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-959175     Document Type: Review

References (67)

1. Hamid Q, Springall DR, Riveros-Moreno V et al. Induction of nitric oxide synthase in asthma. Lancet 1993; 342: 1510-1513
2. Redington AE, Meng QH, Springall DR et al. Increased expression of inducible nitric oxide synthase and cyclo-oxygenase-2 in the airway epithelium of asthmatic subjects and regulation by corticosteroid treatment. Thorax 2001; 56: 351-357
3. Lundberg JO, Farkas-Szallasi T, Weitzberg E et al. High nitric oxide production in human paranasal sinuses. Nat Med 1995; 1: 370-373
4. Jörres RA. Modelling the production of nitric oxide within the human airways. Eur Respir J 2000; 16: 555-560
5. Silkoff PE, McClean PA, Slutsky AS et al. Marked flow-dependence of exhaled nitric oxide using a new technique to exclude nasal nitric oxide. Am J Respir Crit Care Med 1997; 155: 260-267
6. ATS/ERS. Recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide in adults and children. Am J Respir Crit Care Med 2005; 171: 912-930
7. Olin AC, Rosengren A, Thelle DS et al. Height, age, and atopy are associated with fraction of exhaled nitric oxide in a large adult general population sample. Chest 2006; 130: 1319-1325
8. 2-agonist inhalation and spirometry in asthma. Am J Respir Crit Care Med 1999; 159: 940-944
9. Beier J, Beeh KM, Kornmann O et al. Sputum induction leads to a decrease of exhaled nitric oxide unrelated to airflow. Eur Respir J 2003; 22: 354-357
10. Georges G, Bartelson BB, Martin RJ et al. Circadian variation in exhaled nitric oxide in nocturnal asthma. J Asthma 1999; 36: 467-473
11. Yates DH, Breen H, Thomas PS. Passive smoke inhalation decreases exhaled nitric oxide in normal subjects. Am J Respir Crit Care Med 2001; 164: 1043-1046
12. Kharitonov SA, Robbins RA, Yates D et al. Acute and chronic effects of cigarette smoking on exhaled nitric oxide. Am J Respir Crit Care Med 1995; 152: 609-612
13. De Gouw HW, Grunberg K, Schot R et al. Relationship between exhaled nitric oxide and airway hyperresponsiveness following experimental rhinovirus infection in asthmatic subjects. Eur Respir J 1998; 11: 126-132
14. Kharitonov SA, Yates D, Barnes PJ. Increased nitric oxide in exhaled air of normal human subjects with upper respiratory tract infections. Eur Respir J 1995; 8: 295-297
15. Olin AC, Aldenbratt A, Ekman A et al. Increased nitric oxide in exhaled air after intake of a nitrate-rich meal. Respir Med 2001; 95: 153-158
16. Bruce C, Yates DH, Thomas PS. Caffeine decreases exhaled nitric oxide. Thorax 2002; 57: 361-363
17. Deykin A, Massaro AF, Coulston E et al. Exhaled nitric oxide following repeated spirometry or repeated plethysmography in healthy individuals. Am J Respir Crit Cate Med 2000; 161: 1237-1240
18. Müller KC, Jörres RA, Magnussen H et al. Comparison of exhaled nitric oxide analysers. Respir Med 2005; 99: 631-637
19. Olin AC, Alving K, Toren K. Exhaled nitric oxide: relation to sensitization and respiratory symptoms. Clin Exp Allergy 2004; 34: 221-226
20. Malmberg LP, Petays T, Haahtela T et al. Exhaled nitric oxide in healthy nonatopic school-age children: determinants and height-adjusted reference values. Pediatr Pulmonol 2006; 41: 635-642
21. Buchvald F, Baraldi E, Carraro S et al. Measurements of exhaled nitric oxide in healthy subjects age 4 to 17 years. J Allergy Clin Immunol 2005; 115: 1130-1136
22. Olivieri M, Talamini G, Corradi M et al. Reference values for exhaled nittic oxide (reveno) study. Respir Res 2006; 7: DOI: 10.1186/ 1465-9921-7-94
23. Revised GINA guidelines 2006. Global initiative for asthma. National Institutes of Health, National Heart, Lung and Blood Institute. NIH Publication No 02-3659, 2002
24. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. Am J Respir Crit Care Med 2001; 163: 1256-1276; Forthe update of definitions (2004) see: http://www.goldcopd.com/
25. Barnes PJ, Chowdhury B, Kharitonov SA et al. Pulmonary biomarkers in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2006; 174: 6-14
26. Grönke L, Kanniess F, Holz O et al. The relationship between airway hyper-responsiveness, markers of inflammation and lung function depends on the duration of the asthmatic disease. Clin Exp Allergy 2002; 32: 57-63
27. Alving K, Janson C, Nordvall L. Performance of a new hand-held device for exhaled nitric oxide measurement in adults and children. Respir Res 2006; 7: DOI: 10.1186/1165-9921-7-67
28. Pijnenburg MW, Hofhuis W, Hop WC et al. Exhaled nitric oxide predicts asthma relapse in children with clinical asthma remission. Thorax 2005; 60: 215-218
29. Pijnenburg MW, Bakker EM, Hop WC et al. Titrating steroids on exhaled nitric oxide in children with asthma: a randomized controlled trial. Am J Respir Crit Care Med 2005; 172: 831-836
30. Zacharasiewicz A, Wilson N, Lex C et al. Clinical use of noninvasive measurements of airway inflammation in steroid reduction in children. Am J Respir Crit Care Med 2005; 171: 1077-1082
31. Smith AD, Cowan JO, Brassett KP et al. Use of exhaled nitric oxide measurements to guide treatment in chronic asthma. N Engl J Med 2005; 352: 2163-2173
32. Gibson PG, Fujimura M, Niimi A. Eosinophilic bronchitis: clinical manifestations and implications for treatment. Thorax 2002; 57: 178-182
33. Brightling CE, Green RH, Pavord ID. Biomarkers predicting response to corticosteroid therapy in asthma. Treat Respir Med 2005; 4: 309-316
34. Pizzichini MM, Pizzichini E, Parameswaran K et al. Nonasthmatic chronic cough: No effect of treatment with an inhaled corticosteroid in patients without sputum eosinophilia. Can Respir J 1999; 6: 323-330
35. Pavord ID, Brightling CE, Woltmann G et al. Non-eosinophilic corticosteroid unresponsive asthma. Lancet 1999; 353: 2213-2214
36. Green RH, Brightling CE, McKenna S et al. Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial. Lancet 2002; 360: 1715-1721
37. Berry MA, Shaw DE, Green RH et al. The use of exhaled nitric oxide concentration to identify eosinophilic airway inflammation: an observational study in adults with asthma. Clin Exp Allergy 2005; 35: 1175-1179
38. Smith AD, Cowan JO, Brassett KP et al. Exhaled nitric oxide: a predictor of steroid response. Am J Respir Crit Care Med 2005; 172: 453-459
39. Szefler SJ, Phillips BR, Martinez FD et al. Characterization of within-subject responses to fluticasone and montelukast in childhood asthma. J Allergy Clin Immunol 2005; 115: 233-242
40. Little SA, Chalmers GW, MacLeod KJ et al. Non-invasive markers of airway inflammation as predictors of oral steroid responsiveness in asthma. Thorax 2000; 55: 232-234
41. Beck-Ripp J, Griese M, Arenz S et al. Changes of exhaled nitric oxide during steroid treatment of childhood asthma. Eur Respir J 2002; 19: 1015-1019
42. Jones SL, Kittelson J, Cowan JO et al. The predictive value of exhaled nitric oxide measurements in assessing changes in asthma control. Am J Respir Crit Care Med 2001; 164: 738-743
43. Pavord I. The new paradigm: assessing airway inflammation rather than diagnostic labelling is a movement not a fad. 2006: http://www. ersnet.org/ers/lr/browse/
44. Dupont LJ, Demedts MG, Verleden GM. Prospective evaluation of the validity of exhaled nitric oxide for the diagnosis of asthma. Chest 2003; 123: 751-756
45. Smith AD, Cowan JO, Filsell S et al. Diagnosing asthma: comparisons between exhaled nitric oxide measurements and conventional tests. Am J Respir Crit Care Med 2004; 169: 473-478
46. Ichinose M, Sugiura H, Yamagata S et al. Xanthine oxidase inhibition reduces reactive nitrogen species production in COPD airways. Eur Respir J 2003; 22: 457-461
47. Wewel AR, Crusius JA, Gatzemeier U et al. Time course of exhaled hydrogen peroxide and nitric oxide during chemotherapy. Eur Respir J 2006; 27: 1033-1039
48. Brightling CE, Monteiro W, Ward R et al. Sputum eosinophilia and short-term response to prednisolone in chronic obstructive pulmonary disease: a randomised controlled trial. Lancet 2000; 356: 1480-1485
49. Zietkowski Z, Kucharewicz I, Bodzenta-Lukaszyk A. The influence of inhaled corticosteroids on exhaled nitric oxide in stable chronic obsttuctive pulmonary disease. Respir Med 2005; 99: 816-824
50. Kharitonov SA, Barnes PJ. Clinical aspects of exhaled nitric oxide. Eur Respir J 2000; 16: 781-792
51. Haley KJ, Drazen JM. Inflammation and airway function in asthma: what you see is not necessarily what you get. Am J Respir Crit Care Med 1998; 157: 1-3
52. Pizzichini MM, Pizzichini E, Clelland L et al. Prednisone-dependent asthma: inflammatory indices in induced sputum. Eur Respir J 1999; 13: 15-21
53. Leuppi JD, Salome CM, Jenkins CR et al. Predictive markers of asthma exacerbation during stepwise dose reduction of inhaled corticosteroids. Am J Respir Crit Care Med 2001; 163: 406-412
54. Deykin A, Lazarus SC, Fahy JV et al. Sputum eosinophil counts predict asthma control after discontinuation of inhaled corticosteroids. J Allergy Clin Immunol 2005; 115: 720-727
55. Jatakanon A, Lim S, Barnes PJ. Changes in sputum eosinophils predict loss of asthma control. Am J Respir Crit Care Med 2000; 161: 64-72
56. Jayaram L, Pizzichini MM, Cook RJ et al. Determining asthma treatment by monitoring sputum cell counts: effect on exacerbations. Eur Respir J 2006; 27: 483-494
57. Kharitonov SA, Yates DH, Barnes PJ. Inhaled glucocorticoids decrease nitric oxide in exhaled air of asthmatic patients. Am J Respir Crit Care Med 1996; 153: 454-457
58. Jones SL, Herbison P, Cowan JO et al. Exhaled NO and assessment of anti-inflammatory effects of inhaled steroid: dose-response relationship. Eur Respir J 2002; 20: 601-608
59. Shaw DE, Berry ME, Thomas M et al. Asthma exacerbations and exhaled nitric oxide: a randomised controlled trial. Eur Respir J 2006; 28: 572s
60. Djukanovic R, Sterk PJ, Fahy JV et al. Standardised methodology of sputum induction and processing. Eur Respir J 2002; 20: 1S-55S
61. Lex C, Ferreira F, Zacharasiewicz A et al. Airway Eosinophilia in Children with Severe Asthma: Predictive Values of Noninvasive Tests. Am J Respir Crit Care Med 2006; 174: 1286-1291
62. Haldar P, Haldar M, Green RH et al. Discordance between sputum eosinophil counts and exhaled nitric oxide levels in asthma. Eur Respir J 2006; 28: 113s
63. Holz O, Jörres RA. [Non-invasive methods for monitoring airway inflammation: a comparison of expenditures, gain and clinical value]. Pneumologie 2004; 58: 510-515
64. Taylor DR, Pijnenburg MW, Smith AD et al. Exhaled nitric oxide measurements: clinical application and interpretation. Thorax 2006; 61: 817-827
65. Seiler T, Holz O, Karmeier A et al. Sputum-Zytologie in der klinischen Praxis. Pneumologie 2005; 59: S59
66. Hargreave FE, Parameswaran K. Problems with using exhaled nitric oxide to guide asthma treatment. J Allergy Clin Immunol 2006; 117: 1511-1512
67. Holz O, Mücke M, Zarza P et al. Freezing of homogenized sputum samples for intermittent storage. Clin Exp Allergy 2001; 31: 1328-1331