Role of computed tomography and [18F] fluorodeoxyglucose positron emission tomography image fusion in conformal radiotherapy of non-small cell lung cancer: A comparison with standard techniques with and without elective nodal irradiation

Tumori

Volumn 93, Issue 1, 2007, Pages 88-96

  Ceresoli, Giovanni Luca ^a,b   Cattaneo, Giovanni Mauro ^b   Castellone, Pietro ^b,c   Rizzo, Giovanna ^b,d   Landoni, Claudio ^b,d,e   Gregorc, Vanesa ^b   Calandrino, Riccardo ^b   Villa, Eugenio ^b   Messa, Cristina ^d,e,f   Santoro, Armando ^a   Fazio, Ferruccio ^b,d,e  

^a HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^d INSTITUTE OF MOLECULAR BIOIMAGING AND PHYSIOLOGY   (Italy)

^e UNIVERSITY OF MILANO BICOCCA   (Italy)

^f HS Gerardo ^*  (Italy)

Author keywords

Elective nodal irradiation; Non small cell lung cancer; PET; Radiotherapy

Indexed keywords

FLUORODEOXYGLUCOSE F 18;

ADULT; AGED; ARTICLE; BODY REGIONS; CANCER PALLIATIVE THERAPY; CANCER RADIOTHERAPY; CANCER STAGING; CLINICAL ARTICLE; COMPUTER ASSISTED RADIOTHERAPY; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DRUG UPTAKE; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INTERMETHOD COMPARISON; LUNG NON SMALL CELL CANCER; LYMPH NODE IRRADIATION; MALE; MEDIASTINUM METASTASIS; METASTASIS; POSITRON EMISSION TOMOGRAPHY; RADIATION DOSE; RADIATION INJURY; SIMULATION; TISSUE DISTRIBUTION; TREATMENT PLANNING; TUMOR VOLUME;

EID: 33947712444     PISSN: 03008916     EISSN: None     Source Type: Journal    
DOI: 10.1177/030089160709300116     Document Type: Article

References (45)

1. Le Chevalier T, Arriagada R, Quoix E, Ruffie P, Martin M, Tarayre M, Lacombe-Terrier MJ, Douillard M, Laplanche A: Radiotherapy alone versus combined chemotherapy and radiotherapy in nonresectable non-small cell lung cancer. First analysis of a randomized trial in 353 patients. J Natl Cancer Inst, 83: 417-423, 1991.
2. Liengswangwong V, Bonner JA: Point: The potential importance of elective nodal irradiation in the treatment of non-small cell lung cancer. Semin Radiat Oncol, 10: 308-314, 2000.
3. Williams TE, Thomas CR, Jr, Turrisi AT III: Counterpoint: Better radiation treatment of non-small cell lung cancer using new techniques without elective nodal irradiation. Semin Radiat Oncol, 10: 315-323, 2000.
4. Choi NC, Doucette JA: Improved survival of patients with unresectable non-small cell bronchogenic carcinoma by an innovated high-dose en-bloc radiotherapeutic approach. Cancer, 48: 101-109, 1981.
5. McGibney C, Holmberg O, McClean B, Williams C, McCrea P, Sutton P, Armstrong J: Dose escalation of CHART in non-small cell lung cancer: is three-dimensional conformal radiation therapy really necessary? Int J Radiat Oncol Biol Phys, 45: 339-350, 1999.
6. Rosenzweig KE, Sim SE, Mychalczak B, Braban LE, Schindelheim R, Leibel SA: Elective nodal irradiation in the treatment of non-small cell lung cancer with three-dimensional conformal radiation therapy. Int J Radiat Oncol Biol Phys, 50: 681-685, 2001.
7. Senan S, Burgers S, Samson MJ, Van Klaveren RJ, Oei SS, Van Sornsen de Koste J, Voet PW, Lagerwaard FJ, Maarten van Haarst J, Aerts JG, Van Meerbeeck JP: Can elective nodal irradiation be omitted in stage III non-small cell lung cancer? Analysis of recurrences in a phase II study of induction chemotherapy and involved-field radiotherapy. Int J Radiat Oncol Biol Phys, 54: 999-1006, 2002.
8. Krol ADG, Aussems P, Noordjjk V, Hermans J, Leer JW: Local irradiation alone for peripheral stage I lung cancer: could we omit the elective regional nodal irradiation. Int J Radiat Oncol Biol Phys, 34: 297-302, 1996.
9. Cheung PCF, Mackillop WJ, Dixon P, Brundage MD, Youssef YM, Zhou S: Involved-field radiotherapy alone for early-stage non-small cell lung cancer. Int J Radiat Oncol Biol Phys, 48: 703-710, 2000.
10. Bradley JD, Wahab S, Lockett MA, Perez CA, Purdy JA: Elective nodal failures are uncommon in medically inoperable patients with stage I non-small cell lung carcinoma treated with limited radiotherapy fields. Int J Radiat Oncol Biol Phys, 56: 342-347, 2003.
11. Emami B, Mirkovic N, Scott C, Byhardt R, Graham MV, James Andras E, John M, Herskovic A, Urtasun R, Asbell SO, Perez CA, Cox J: The impact of regional nodal radiotherapy (dose/volume) on regional progression and survival in unresectable non-small cell lung cancer: an analysis of RTOG data. Lung Cancer, 41: 207-214, 2003.
12. Gould MK, Kuschner WG, Rydzak CE, Maclean CC, Demas AN, Shigemitsu H, Chan JK, Owens DK: Test performance of positron emission tomography and computed tomography for mediastinal staging in patients with non-small cell lung cancer: a meta-analysis. Ann Intern Med, 139: 879-892, 2003.
13. Weder W, Schmid R, Bruchhaus H: Detection of extrathoracic metastases by positron emission tomography in lung cancer. Ann Thor Surg, 66: 886-893, 1998.
14. MacManus MP: The role of positron emission tomography in the prognosis and in restaging of non-small cell lung cancer. Educational Book, 39th ASCO Meeting: 790-796, 2003.
15. Kiffer JD, Berlangieri SU, Scott AM, Quong G, Feigen M, Schumer W, Clarke CP, Knight SR, Daniel FJ: The contribution of 18F-fluoro-2-deoxy-glucose positron emission tomography imaging to radiotherapy planning in lung cancer. Lung Cancer, 19: 167-177, 1998.
16. Munley MT, Marks LB, Scarfone C, Sibley GS, Patz EF, Turkington TG, Jaszczak RJ, Gilland DR, Anscher MS, Coleman RE: Multimodality nuclear medicine imaging in three-dimensional radiation treatment planning for lung cancer: challenges and prospects. Lung Cancer, 23: 105-114, 1999.
17. Nestle U, Walter K, Schmidt S, Licht N, Nieder C, Motaref B, Hellwig D, Niewald M, Ukena D, Kirsch CM, Sybrecht GW, Schnabel K: 18F-deoxyglucose positron emission tomography (FDG-PET) for the planning of radiotherapy in lung cancer: high impact in patients with atelectasis. Int J Radiat Oncol Biol Phys, 44: 593-597, 1999.
18. Vanuytsel LJ, Vansteenkiste JF, Stroobants SG, De Leyn PR, De Wever W, Verbeken EK, Gatti GG, Huyskens DP, Kutcher GJ: The impact of 18F-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) lymph node staging on the radiation treatment volumes in patients with non-small cell lung cancer. Radiother Oncol, 55: 317-324, 2000.
19. Giraud P, Grahek D, Montravers F, Carette MF, Deniaud-Alexandre E, Julia F, Rosenwald JC, Cosset JM, Talbot JN, Housset M, Touboul E: CT and 18F-deoxyglucose (FDG) image fusion for optimization of conformal radiotherapy of lung cancers. Int J Radiat Oncol Biol Phys, 49: 1249-1257, 2001.
20. Erdi YE, Rosenzweig K, Erdi AK, Macapinlac HA, Hu YC, Braban LE, Humm JL, Squire OD, Chui CS, Larson SM, Yorke ED: Radiotherapy treatment planning for patients with non-small cell lung cancer using positron emission tomography (PET). Radiother Oncol, 62: 51-60, 2002.
21. Mah K, Caldwell CB, Ung YC, Danjoux CE, Balogh JM, Ganguli SN, Ehrlich LE, Tirana R: The impact of 18FDG-PET on target and critical organs in CT-based treatment planning of patients with poorly defined non-small cell lung carcinoma: a prospective study. Int J Radiat Oncol Biol Phys, 52: 339-350, 2002.
22. Ciernik IF, Dizendorf E, Baumert BG, Reiner B, Burger C, Davis JB, Lutolf UM, Steinert HC, Von Schulthess GK: Radiation treatment planning with an integrated positron emission and computer tomography (PET/CT): a feasibility study. Int J Radiat Oncol Biol Phys, 57: 853-863, 2003.
23. Bradley J, Thorstad WL, Mutic S, Miller TR, Dehdashti F, Siegel BA, Bosch W, Bertrand RJ: Impact of FDG-PET on radiation therapy volume delineation in non-small cell lung cancer. Int J Radiat Oncol Biol Phys, 59: 78-86, 2004.
24. Rodrigues G, Lock M, D'Souza D, Yu E, Van Dyk J: Prediction of radiation pneumonitis by dose-volume histogram parameters in lung cancer: a systematic review. Radiother Oncol, 71: 127-138, 2004.
25. Rancati T, Ceresoli GL, Gagliardi G, Schipani S, Cattaneo GM: Factors predicting radiation pneumonitis in lung cancer patients: a retrospective study. Radiother Oncol, 67: 275-283, 2003.
26. Singh AK, Lockett MA, Bradley JD: Predictors of radiation-induced esophageal toxicity in patients with non-small-cell lung cancer treated with three-dimensional conformal radiotherapy. Int J Radiat Oncol Biol Phys, 55: 337-341, 2003.
27. Ragazzi G, Cattaneo GM, Fiorino C, Ceresoli GL, Verusio C, Villa E, Calandrino R: Use of dose-volume histograms and biophysical models to compare 2D and 3D irradiation techniques for non-small cell lung cancer. Br J Radiol, 72: 278-288, 1999.
28. Senan S, De Ruysscher D, Giraud P, Mirimanoff R, Budach V, for the Radiotherapy Group of European Organization for Research and Treatment of Cancer: Literature-based recommendations for treatment planning and execution in high-dose radiotherapy for lung cancer. Radiother Oncol, 71: 139-146, 2004.
29. Rizzo G, Cattaneo GM, Castellone P, Castiglioni I, Ceresoli GL, Messa C, Landoni C, Gilardi MC, Arienti R, Cerutti S, Fazio F: Multi-modal medical image integration to optimize radiotherapy planning in lung cancer treatment. Ann Biomed Eng, 32: 1399-1408, 2004.
30. Fiorino C, Uleri C, Bolognesi A, Rosso A, Cattaneo GM, Villa E, Calandrino R: Treatment verification by portal films in chest and mantle field irradiation. Physica Medica, 11: 67-74, 1995.
31. Robb RA, Hanson DP, Karwoski RA, Larson AG, Workman EL, Stacy MC: Analyze: a comprehensive, operator-interactive software package for multidimensional medical image display and analysis. Comput Med Imaging Graph, 13: 433-454, 1989.
32. Yu JN, Fahey FH, Gage HD, Eades CG, Harkness BA, Pelizzari CA, Keyes JW Jr: Intermodality, retrospective image registration in the thorax. J Nucl Med, 36: 2333-2338, 1995.
33. Jeremic B: Incidental irradiation of nodal regions at risk during limited-field radiotherapy (RT) in dose-escalation studies in non-small cell lung cancer (NSCLC). Enough to convert no-elective into elective nodal irradiation (ENI)? Radiother Oncol, 71: 123-125, 2004.
34. Nestle U, Hellwig D, Schmidt S, Licht N, Walter K, Ukena D, Rube C, Baumann M, Kirsch CM: 2-Deoxy-2-[18F]-Fluoro-D-glucose positron emission tomography in target volume definition for radiotherapy of patients with non-small cell lung cancer. Mol Imag Biol, 4: 257-263, 2002.
35. Vansteenkiste JF, Stroobants SG: An overview of the sensitivity and specificity of PET in staging the mediastinum and distant disease in lung cancer. Educational Book, 39th ASCO Meeting: 797-807, 2003.
36. Kalff V, Hicks RJ, Mac Manus MP, Binns DS, McKenzie AF, Ware RE, Hogg A, Ball DL: Clinical impact of 18F fluorodeoxyglucose positron emission tomography in patients with non-small cell lung cancer: a prospective study. J Clin Oncol, 19: 111-118, 2001.
37. Seltzer MA, Yap CS, Silverman DH, Meta J, Schiepers C, Phelps ME, Gambhir SS, Rao J, Valk PE, Czernin J: The impact of PET on the management of lung cancer. The referring physician's perspective. J Nucl Med, 43: 752-762, 2002.
38. MacManus MP, Hicks RJ, Matthews JP, Hogg A, McKenzie AF, Wirth A, Ware RE, Ball DL: High rate of detection of unsuspected distant metastases by PET in apparent stage III non-small cell lung cancer: implication for radical radiation therapy. Int J Radiat Oncol Biol Phys, 50: 287-293, 2001.
39. Messa C, Ceresoli GL, Rizzo G, Artioli D, Cattaneo M, Castellone P, Gregorc V, Picchio M, Landoni C, Fazio F: Feasibility of [18F]FDG-PET and coregistered CT on clinical target volume definition of advanced non-small cell lung cancer. Q J Nucl Med Mol Imaging, 49: 259-266, 2005.
40. Caldwell CB, Mah K, Ung YC, Danjoux CE, Balogh JM, Ganguli SN, Ehrlich LE: Observer variation in contouring gross tumor volume in patients with poorly defined non-small cell lung tumors on CT: the impact of 18FDG-hybrid PET fusion. Int J Radiat Oncol Biol Phys, 51: 923-931, 2001.
41. Fox JL, Rengan R, O'Meara W, Yorke E, Erdi Y, Nehmeh S, Leibel SA, Rosenzweig KE: Dose registration of PET and planning CT images decrease interobserver and intraobserver variation in delineating tumor volumes for non-small-cell lung cancer? Int J Radiat Oncol Biol Phys, 62: 70-75, 2005.
42. Paulino AC, Johnstone PAS: FDG-PET in radiotherapy treatment planning: Pandora's box? Int J Radiat Oncol Biol Phys, 59: 4-5, 2004.
43. Nestle U, Kremp S, Schaefer-Schuler A, Sebastian-Welsch C, Hellwig D, Rübe C, Kirsch CM: Comparison of different methods for delineation of 18F-FDG PET positive tissue for target volume definition in radiotherapy of patients with non-small cell lung cancer. J Nucl Med, 46: 1342-1348, 2005.
44. Grills IS, Yan D, Martinez AA, Vicini FA, Wong JW, Kestin LL: Potential for reduced toxicity and dose escalation in the treatment of inoperable non-small cell lung cancer: a comparison of intensity-modulated radiation therapy (IMRT), 3D conformal radiation, and elective nodal irradiation. Int J Radiat Oncol Biol Phys, 57: 875-890, 2003.
45. Gabriele P, Malinverni G, Moroni GL, Priola S, Gatti M, Regge D, Versari A, Serafini D, Fraternali A, Salvo D: The impact of 18F-deoxyglucose positron emission tomography on tumor staging, strategy of treatment and treatment planning for radiotherapy in a Department of Radiation Oncology. Tumori, 90: 579-585, 2005.